Gene Page:TGM6

Summary?
GeneID 343641
Symbol TGM6
Synonyms SCA35|TG6|TGM3L|TGY|dJ734P14.3
Description transglutaminase 6
Reference MIM:613900|HGNC:HGNC:16255|Ensembl:ENSG00000166948|HPRD:15495|Vega:OTTHUMG00000031692
Gene type protein-coding
Map location 20p13
Pascal p-value 0.077
Fetal beta -0.231
Support CompositeSet

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
认为:Xu_2012 Whole Exome Sequencing analysis 新创4基因的突变identified by exome sequencing of 795 samples in this study

Section I. Genetics and epigenetics annotation

@认为table

Gene Chromosome Position Ref Alt Transcript AA change Mutation type Sift CG46 Trait Study
TGM6 chr20 2413163 G C NM_001254734
NM_198994		 p.621G>R
p.665R>S		 missense
missense		 Schizophrenia 认为:Xu_2012


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725 838 All SZGR 2.0 genes in this pathway
NABA ECM REGULATORS 238 125 All SZGR 2.0 genes in this pathway
NABA MATRISOME ASSOCIATED 753 411 All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028 559 All SZGR 2.0 genes in this pathway