Gene Page:INPP5B
Summary?
| GeneID | 3633 |
| Symbol | INPP5B |
| Synonyms | 5PTase |
| Description | inositol polyphosphate-5-phosphatase B |
| Reference | MIM:147264|HGNC:HGNC:6077|Ensembl:ENSG00000204084|HPRD:00924|Vega:OTTHUMG00000004436 |
| Gene type | protein-coding |
| Map location | 1p34 |
| Pascal p-value | 0.005 |
| eGene | Caudate basal ganglia Cerebellar Hemisphere 小脑 元 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
某fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ZNF518B | 0.97 | 0.98 |
| PPP2R5E | 0.96 | 0.97 |
| AP001011.3 | 0.96 | 0.96 |
| LATS1 | 0.96 | 0.97 |
| ZMYM2 | 0.96 | 0.97 |
| ANKRD50 | 0.96 | 0.96 |
| SCYL2 | 0.96 | 0.97 |
| USP37 | 0.96 | 0.95 |
| MED13 | 0.96 | 0.96 |
| ZNF699 | 0.95 | 0.96 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| FXYD1 | -0.73 | -0.88 |
| AF347015.31 | -0.72 | -0.86 |
| MT-CO2 | -0.71 | -0.88 |
| AIFM3 | -0.71 | -0.76 |
| TSC22D4 | -0.71 | -0.79 |
| HSD17B14 | -0.70 | -0.79 |
| HLA-F | -0.70 | -0.76 |
| S100B | -0.70 | -0.81 |
| AF347015.33 | -0.70 | -0.83 |
| IFI27 | -0.69 | -0.85 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG INOSITOL PHOSPHATE METABOLISM | 54 | 42 | All SZGR 2.0 genes in this pathway |
| KEGG PHOSPHATIDYLINOSITOL SIGNALING SYSTEM | 76 | 56 | All SZGR 2.0 genes in this pathway |
| SLEBOS HEAD AND NECK CANCER WITH HPV UP | 84 | 43 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN RESPONSE TO MC AND DOXORUBICIN UP | 612 | 367 | All SZGR 2.0 genes in this pathway |
| PEREZ TP53 TARGETS | 1174 | 695 | All SZGR 2.0 genes in this pathway |
| LOPEZ MBD TARGETS | 957 | 597 | All SZGR 2.0 genes in this pathway |
| YE METASTATIC LIVER CANCER | 27 | 13 | All SZGR 2.0 genes in this pathway |
| VARELA ZMPSTE24 TARGETS DN | 38 | 18 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 12HR DN | 101 | 64 | All SZGR 2.0 genes in this pathway |
| MATZUK SPERMATOZOA | 114 | 77 | All SZGR 2.0 genes in this pathway |
| ELLWOOD MYC TARGETS DN | 40 | 27 | All SZGR 2.0 genes in this pathway |
| KESHELAVA MULTIPLE DRUG RESISTANCE | 88 | 56 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 4HR DN | 254 | 158 | All SZGR 2.0 genes in this pathway |
| PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY | 1839 | 928 | All SZGR 2.0 genes in this pathway |