SZGR2 - Beplay体育中心

Summary？

GeneID	367
Symbol	ar
Synonyms	AIS\|AR8\|DHTR\|HUMARA\|HYSP1\|KD\|NR3C4\|SBMA\|SMAX1\|TFM
Description	雄激素受体
Reference	MIM:313700\|HGNC:HGNC:644\|Ensembl:ENSG00000169083\|HPRD:02437\|Vega：Otthumg00000021740
Gene type	蛋白质编码
Map location	Xq12
胎儿β	-0.408

Gene in Data Sources

Gene set name	Method of gene set	Description	信息
CV:PGCnp	Genome-wide Association Study	GWAS
PMID：cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Association	A combined odds ratio method (Sun et al. 2008），协会研究	1	Link to SZGene
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizotypy,schizophrenias,schizotypal	点击显示详细信息
GO_Annotation	Mapping neuro-related keywords to Gene Ontology annotations	Hits with neuro-related keywords: 1
Network	短est path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 0.1813

Section I. Genetics and epigenetics annotation

第二节。转录组注释

一般基因表达（GTEX）

Gene expression during devlopment (BrainCloud)

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

第三节。基因本体论注释

分子功能	去学期	证据	神经关键字	PubMed ID
去：0005102	receptor binding	IPI	Neurotransmitter (GO term level: 4)	11875111
GO:0004872	receptor activity	IEA		-
去：0004882	雄激素受体activity	IEA		-
去：0004882	雄激素受体activity	NAS		10075738
去：0004882	雄激素受体activity	TAS		15572661
GO:0003700	transcription factor activity	IDA		15572661
GO:0003700	transcription factor activity	IEA		-
GO:0005496	steroid binding	IEA		-
GO:0005497	雄激素结合	NAS		10075738
GO:0008270	zinc ion binding	IEA		-
GO:0046872	metal ion binding	IEA		-
GO:0043565	sequence-specific DNA binding	IEA		-
GO:0046983	protein dimerization activity	NAS		10075738
Biological process	去学期	证据	神经关键字	PubMed ID
GO:0001701	in utero embryonic development	IEA		-
GO:0006355	调节转录，DNA依赖性的调节	IEA		-
GO:0006350	transcription	IEA		-
GO:0016049	cell growth	NAS		15572661
GO:0007267	细胞细胞信号传导	TAS		10835690
GO:0007165	信号转导	TAS		10835690
GO:0008283	cell proliferation	NAS		10075738
GO:0008584	male gonad development	IEA		-
GO:0007548	sex differentiation	NAS		10075738
GO:0006810	transport	TAS		10835690
GO:0030850	prostate gland development	NAS		10075738
GO:0019102	male somatic sex determination	IEA		-
GO：0030521	雄激素受体信号通路	IEA		-
Cellular component	去学期	证据	神经关键字	PubMed ID
GO:0005634	nucleus	IDA		15572661
GO:0005634	nucleus	IEA		-
去：0005737	细胞质	IDA		15572661

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	实验	资源	PubMed ID
AES	AES-1 \| AES-2 \| ESP1 \| GRG \| GRG5 \| TLE5	amino-terminal enhancer of split	-	HPRD,BioGRID	11416139
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	Akt磷酸化AR。	BIND	11404460\|12621049
AKT1	AKT \| MGC99656 \| PKB \| PKB-ALPHA \| PRKBA \| RAC \| RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	11404460
ar	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	雄激素受体	生化活动共晶结构 Protein-peptide Two-hybrid	Biogrid	11504717\|12612084 \|12682292\|14593076 \|14729952\|14966121 \|14966297\|15062556 \|15256534\|15525515
BAG1	RAP46	BCL2-associated athanogene	-	HPRD,BioGRID	11278763
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	breast cancer 1, early onset	-	HPRD,BioGRID	11016951\|11085509
CALM1	CALML2 \| CAMI \| DD132 \| PHKD	calmodulin 1 (phosphorylase kinase, delta)	亲和力捕获 - 韦斯特恩 Co-localization 重构的复合物	Biogrid	14695896
CALR	CRT \| FLJ26680 \| RO \| SSA \| cC1qR	calreticulin	-	HPRD,BioGRID	8107809
CASP1	ICE \| IL1BC \| P45	caspase 1，与凋亡相关的半胱氨酸肽酶（白介素1，β，转化酶）	雄激素受体与caspase 1相互作用。这种相互作用是基于未指定物种的人类雄激素受体和caspase 1的相互作用建模的。	BIND	9535906
CASP3	CPP32 \|CPP32B \|SCA-1	caspase 3, apoptosis-related cysteine peptidase	雄激素受体与caspase3相互作用。这种相互作用是基于未指定物种的人类雄激素受体和caspase 3之间的相互作用建模的。	BIND	9535906
CASP7	CMH-1 \| ICE-LAP3 \| MCH3	caspase 7, apoptosis-related cysteine peptidase	雄激素受体与caspase 7相互作用。	BIND	9535906
CASP8	ALPS2B \|cap4 \|弗里斯\|FLJ17672 \|马赫\|MCH5 \|MGC78473	caspase 8, apoptosis-related cysteine peptidase	雄激素受体与caspase 8相互作用。	BIND	9535906
CAV1	cav \|MSTP085 \|VIP21	小窝蛋白1，小窝蛋白，22KDA	-	HPRD,BioGRID	11278309
CAV1	cav \|MSTP085 \|VIP21	小窝蛋白1，小窝蛋白，22KDA	Caveolin-1 interacts with AR.	BIND	11278309
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	-	HPRD,BioGRID	10344732
CCNE1	CCNE	cyclin E1	-	HPRD,BioGRID	10953010
CCNH	CAK \| p34 \| p37	cyclin H	重构的复合物	Biogrid	10734072
cdc25b	-	cell division cycle 25 homolog B (S. pombe)	-	HPRD,BioGRID	12569365
CDC37	P50CDC37	cell division cycle 37 homolog (S. cerevisiae)	-	HPRD,BioGRID	11085988
CDK7	cak1 \|CDKN7 \|mo15 \|STK1 \|P39MO15	cyclin-dependent kinase 7	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	10734072
CDK9	C-2k \| CDC2L4 \| CTK1 \| PITALRE \| TAK	cyclin-dependent kinase 9	-	HPRD,BioGRID	11266437
CEBPA	C/EBP-Alpha \|CEBP	CCAAT/enhancer binding protein (C/EBP), alpha	重构的复合物	Biogrid	9817600
CEBPB	C/EBP-beta \| CRP2 \| IL6DBP \| LAP \| MGC32080 \| NF-IL6 \| TCF5	CCAAT /增强子结合蛋白(C / EBP),β	重构的复合物	Biogrid	9817600
COX5B	COXVB	cytochrome c oxidase subunit Vb	-	HPRD,BioGRID	11719263
克雷布	CBP \| KAT3A \| RSTS	CREB结合蛋白	-	HPRD,BioGRID	9482849
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	-	HPRD,BioGRID	11916967
DAP3	DAP-3 \|DKFZP686G12159 \|MGC126058 \|MGC126059 \|MRP-S29 \|MRPS29 \|BMRP-10	死亡相关蛋白3	-	HPRD,BioGRID	10903152
daxx	Bing2 \|DAP6 \|EAP1 \|MGC126245 \|MGC126246	death-domain associated protein	亲和力捕获 - 韦斯特恩重构的复合物 Two-hybrid	Biogrid	15572661
DCC	CRC18 \| CRCR1	deleted in colorectal carcinoma	亲和力捕获 - 韦斯特恩重构的复合物 Two-hybrid	Biogrid	12864730
efcab6	DJBP \|FLJ23588 \|HSCBCIP1 \|KIAA1672 \|DJ185D5.1	EF-hand calcium binding domain 6	-	HPRD,BioGRID	12612053
egfr	ERBB \| ERBB1 \| HER1 \| PIG61 \| mENA	表皮生长因子受体（红细胞性白血病病毒（V-ERB-B）癌基因同源物，鸟类）	亲和力捕获 - 韦斯特恩 Co-localization	Biogrid	15288768\|15305378
ESR1	DKFZp686N23123 \| ER \| ESR \| ESRA \| Era \| NR3A1	雌激素受体1	-	HPRD,BioGRID	12389206
ETV5	ERM	ets variant 5	重构的复合物	Biogrid	8798622
ETV5	ERM	ets variant 5	-	HPRD	11509567
FGF8	AIGF \| HBGF-8 \| MGC149376	成纤维细胞生长因子8（雄激素诱导）	arinteracts with FGF8 promoter.	BIND	12140757
FHL2	AAG11 \|Dral \|Slim3	four and a half LIM domains 2	-	HPRD,BioGRID	10654935
flna	ABP-280 \| ABPX \| DKFZp434P031 \| FLN \| FLN1 \| FMD \| MNS \| NHBP \| OPD \| OPD1 \| OPD2	filamin A, alpha (actin binding protein 280)	-	HPRD,BioGRID	12682292
FOXA1	HNF3A \| MGC33105 \| TCF3A	forkhead box A1	-	HPRD,BioGRID	12750453
FOXO1	FKH1 \| FKHR \| FOXO1A	forkhead box O1	-	HPRD,BioGRID	12482965
GAPDH	G3PD \| GAPD \| MGC88685	3-磷酸甘油醛脱氢酶	-	HPRD,BioGRID	8872471
GNB2L1	GNB2-RS1 \|H12.3 \|HLC-7 \|PIG21 \|机架1	鸟嘌呤核苷酸结合蛋白（G蛋白），β多肽2类样1	-	HPRD,BioGRID	12958311
GRIP1	GRIP	glutamate receptor interacting protein 1	Two-hybrid	Biogrid	10607837
GSK3A	DKFZp686D0638	glycogen synthase kinase 3 alpha	亲和力捕获 - 韦斯特恩	Biogrid	15361837
GSK3B	-	糖原合酶激酶3β	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	15178691
GSN	DKFZp313L0718	gelsolin (amyloidosis, Finnish type)	-	HPRD,BioGRID	12941811
GTF2F1	BTF4 \| RAP74 \| TF2F1 \| TFIIF	通用转录因子IIF，多肽1，74KDA	-	HPRD,BioGRID	9238003
GTF2F2	BTF4 \| RAP30 \| TF2F2 \| TFIIF	general transcription factor IIF, polypeptide 2, 30kDa	-	HPRD,BioGRID	9238003
GTF2H1	BTF2 \|TFB1 \|tfiih	general transcription factor IIH, polypeptide 1, 62kDa	-	HPRD,BioGRID	10734072\|11266437
HDAC1	DKFZp686H12203 \| GON-10 \| HD1 \| RPD3 \| RPD3L1	histone deacetylase 1	-	HPRD,BioGRID	11994312
HDAC3	HD3 \| RPD3 \| RPD3-2	histone deacetylase 3	重构的复合物	Biogrid	12943985
HDAC4	HA6116 \| HD4 \| HDAC-A \| HDACA \| KIAA0288	histone deacetylase 4	重构的复合物	Biogrid	12943985
HMGB1	DKFZp686A04236 \| HMG1 \| HMG3 \| SBP-1	高机动性组框1	-	HPRD,BioGRID	9671457
HMGB2	HMG2	高机动性组框2	重构的复合物	Biogrid	9671457
HNF4A	FLJ39654 \| HNF4 \| HNF4a7 \| HNF4a8 \| HNF4a9 \| MODY \| MODY1 \| NR2A1 \| NR2A21 \| TCF \| TCF14	肝细胞核因子4，α	Co-localization	Biogrid	12944908
HSP90AA1	FLJ31884 \| HSP86 \| HSP89A \| HSP90A \| HSP90N \| HSPC1 \| HSPCA \| HSPCAL1 \| HSPCAL4 \| HSPN \| Hsp89 \| Hsp90 \| LAP2	heat shock protein 90kDa alpha (cytosolic), class A member 1	-	HPRD,BioGRID	1525041
HSPA1A	FLJ54303 \| FLJ54370 \| FLJ54392 \| FLJ54408 \| FLJ75127 \| HSP70-1 \| HSP70-1A \| HSP70I \| HSP72 \| HSPA1 \| HSPA1B	heat shock 70kDa protein 1A	亲和力捕获 - 韦斯特恩	Biogrid	1540595
IDE	FLJ35968 \| INSULYSIN	胰岛素降解酶	-	HPRD	8051160
IL6st	CD130 \| CDw130 \| GP130 \| GP130-RAPS \| IL6R-beta	interleukin 6 signal transducer (gp130, oncostatin M receptor)	亲和力捕获 - 韦斯特恩	Biogrid	15129430
六月	AP-1 \|AP1 \|C-Jun	jun oncogene	-	HPRD,BioGRID	8798722\|9211894
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K（赖氨酸）乙酰转移酶5	生化活动 Two-hybrid	Biogrid	11994312
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K（赖氨酸）乙酰转移酶5	-	HPRD	10364196
KLK2	klk2a2 \|MGC12201 \|HK2	kallikrein-related peptidase 2	arinteracts with p-KLK-2.	BIND	15542435
KLK3	APS \|KLK2A1 \|PSA \|HK3	kallikrein-related peptidase 3	AR与P-PSA相互作用。	BIND	15542435
MAGEA11	MAGE-11 \| MAGE11 \| MAGEA-11 \| MGC10511	melanoma antigen family A, 11	亲和力捕获 - 韦斯特恩 Co-localization 重构的复合物 Two-hybrid	Biogrid	15684378
MAPK1	ERK \| ERK2 \| ERT1 \| MAPK2 \| P42MAPK \| PRKM1 \| PRKM2 \| p38 \| p40 \| p41 \| p41mapk	有丝分裂原激活的蛋白激酶1	重构的复合物	Biogrid	10318905
MDM2	HDMX \| MGC71221 \| hdm2	Mdm2 p53 binding protein homolog (mouse)	-	HPRD	12145204
MED1	CRSP1 \| CRSP200 \| DRIP205 \| DRIP230 \| MGC71488 \| PBP \| PPARBP \| PPARGBP \| RB18A \| TRAP220 \| TRIP2	mediator complex subunit 1	-	HPRD,BioGRID	12218053
Med14	CRSP150 \| CRSP2 \| CSRP \| CXorf4 \| DRIP150 \| EXLM1 \| MGC104513 \| RGR1 \| TRAP170	mediator complex subunit 14	-	HPRD,BioGRID	12218053
mybbp1a	FLJ37886 \| P160 \| PAP2	MYB binding protein (P160) 1a	-	HPRD	11779876
MYST2	HBO1 \| HBOA \| KAT7	MYST histone acetyltransferase 2	-	HPRD,BioGRID	10930412
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	核受体共激活因子1	SRC-1a interacts with AR.	BIND	10454563
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	核受体共激活因子1	-	HPRD,BioGRID	10567563
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	核受体共激活因子1	SRC-1e interacts with AR.	BIND	10454563
NCOA2	grip1 \|kat13c \|MGC138808 \|NCOA-2 \|tif2	核受体共激活因子2	亲和力捕获 - 韦斯特恩 Protein-peptide 重构的复合物 Two-hybrid	Biogrid	12612084\|12810069 \|14593076\|14966121
NCOA2	grip1 \|kat13c \|MGC138808 \|NCOA-2 \|tif2	核受体共激活因子2	GRIP1 interacts with AR. This interaction was modeled on a demonstrated interaction between mouse GRIP1 and human AR.	BIND	10454563
NCOA2	grip1 \|kat13c \|MGC138808 \|NCOA-2 \|tif2	核受体共激活因子2	-	HPRD	9717843
NCOA2	grip1 \|kat13c \|MGC138808 \|NCOA-2 \|tif2	核受体共激活因子2	-	HPRD	9717843\|12588987
NCOA3	ACTR \| AIB-1 \| AIB1 \| CAGH16 \| CTG26 \| KAT13B \| MGC141848 \| RAC3 \| SRC3 \| TNRC14 \| TNRC16 \| TRAM-1 \| pCIP	核受体共激活因子3	-	HPRD,BioGRID	10965917
NCOA4	arA70 \| DKFZp762E1112 \| ELE1 \| PTC3 \| RFG	核受体共激活因子4	-	HPRD	8643607\|9892017 \|10517667\|11818501
NCOA4	arA70 \| DKFZp762E1112 \| ELE1 \| PTC3 \| RFG	核受体共激活因子4	Far Western Protein-peptide 重构的复合物 Two-hybrid	Biogrid	8643607\|9636157 \|9892017\|10318905 \|10517667\|11404460 \|11779876\|11818501 \|12612084\|14966297
NCOA6	AIB3 \| ANTP \| ASC2 \| HOX1.1 \| HOXA7 \| KIAA0181 \| NRC \| PRIP \| RAP250 \| TRBP	核受体共激活因子6	亲和力捕获 - 韦斯特恩 Two-hybrid	Biogrid	14645241
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	核受体共抑制剂1	-	HPRD,BioGRID	12089345
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	核受体共抑制剂2	亲和力捕获 - 韦斯特恩 Co-localization 重构的复合物 Two-hybrid	Biogrid	11923464\|12441355 \|14593076
NFKB1	DKFZP686C01211 \|EBP-1 \|kbf1 \|MGC54151 \|nf-kappa-b \|NFKB-P105 \|NFKB-P50 \|P105	B细胞中Kappa光多肽基因增强子的核因子1	-	HPRD	8798655
NISCH	FLJ14425 \|FLJ40413 \|FLJ90519 \|I-1 \|iras \|KIAA0975	Nischarin	-	HPRD,BioGRID	15028622
NONO	NMT55 \| NRB54 \| P54 \| P54NRB	non-POU domain containing, octamer-binding	-	HPRD,BioGRID	12810069
NR0B1	AHC \| AHCH \| AHX \| DAX-1 \| DAX1 \| DSS \| GTD \| HHG \| NROB1	nuclear receptor subfamily 0, group B, member 1	-	HPRD,BioGRID	11875111
NR0B2	FLJ17090 \| SHP \| SHP1	nuclear receptor subfamily 0, group B, member 2	-	HPRD,BioGRID	11735420
NR2C1	TR2	nuclear receptor subfamily 2, group C, member 1	-	HPRD,BioGRID	12949936
NR2C2	tak1 \|tr2r1 \|tr4 \|htak1	核受体亚科2,C组,成员2	-	HPRD,BioGRID	10611280
NR3C1	GCCR \|GCR \|gr \|grl	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-	HPRD,BioGRID	9162033
NSD1	arA267 \| DKFZp666C163 \| FLJ10684 \| FLJ22263 \| FLJ44628 \| KMT3B \| SOTOS \| STO	核受体结合集合域蛋白1	-	HPRD	11509567
NSD1	arA267 \| DKFZp666C163 \| FLJ10684 \| FLJ22263 \| FLJ44628 \| KMT3B \| SOTOS \| STO	核受体结合集合域蛋白1	-	HPRD,BioGRID	11266437\|11509567
PA2G4	EBP1 \| HG4-1 \| p38-2G4	proliferation-associated 2G4, 38kDa	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	12165860
PA2G4	EBP1 \| HG4-1 \| p38-2G4	proliferation-associated 2G4, 38kDa	-	HPRD	9565586
PAK6	PAK5	p21 protein (Cdc42/Rac)-activated kinase 6	-	HPRD,BioGRID	11278661
PATZ1	MAZR \| PATZ \| RIAZ \| ZBTB19 \| ZNF278 \| ZSG \| dJ400N23	POZ (BTB) and AT hook containing zinc finger 1	亲和力捕获 - 韦斯特恩	Biogrid	11719514
PELP1	HMX3 \| MNAR \| P160	脯氨酸，谷氨酸和富含亮氨酸蛋白1	-	HPRD,BioGRID	12415108
PIAS1	DDXBP1 \| GBP \| GU/RH-II \| MGC141878 \| MGC141879 \| ZMIZ3	protein inhibitor of activated STAT, 1	-	HPRD	11877418
PIAS1	DDXBP1 \| GBP \| GU/RH-II \| MGC141878 \| MGC141879 \| ZMIZ3	protein inhibitor of activated STAT, 1	Two-hybrid	Biogrid	11117529
PIAS2	MGC102682 \| MIZ1 \| PIASX \| PIASX-ALPHA \| PIASX-BETA \| SIZ2 \| ZMIZ4 \| miz	protein inhibitor of activated STAT, 2	重构的复合物 Two-hybrid	Biogrid	9920921\|11117529
PIAS3	FLJ14651 \|Zmiz5	protein inhibitor of activated STAT, 3	Two-hybrid	Biogrid	11117529
PIAS4	FLJ12419 \|MGC35296 \|Piasy \|piasg \|ZMIZ6	protein inhibitor of activated STAT, 4	-	HPRD,BioGRID	11439351
PNRC1	B4-2 \| PNAS-145 \| PROL2 \| PRR2 \| RP11-63L7.5	proline-rich nuclear receptor coactivator 1	-	HPRD	10428808
PNRC2	FLJ20312 \| MGC99541	proline-rich nuclear receptor coactivator 2	-	HPRD	10894149
POU2F1	OCT1 \| OTF1	POU class 2 homeobox 1	-	HPRD,BioGRID	10480874
POU2F2	OCT2 \| OTF2 \| Oct-2	POU class 2 homeobox 2	重构的复合物	Biogrid	10480874
PRKDC	DNA-PKcs \| DNAPK \| DNPK1 \| HYRC \| HYRC1 \| XRCC7 \| p350	protein kinase, DNA-activated, catalytic polypeptide	Affinity Capture-MS	Biogrid	15640154
PRMT1	ANM1 \| HCP1 \| HRMT1L2 \| IR1B4	protein arginine methyltransferase 1	重构的复合物	Biogrid	11050077
PRPF6	ANT-1 \| C20orf14 \| TOM \| U5-102K \| hPrp6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	-	HPRD,BioGRID	12039962
PSPC1	DKFZp566B1447 \| FLJ10955 \| PSP1	paraspeckle component 1	Affinity Capture-MS	Biogrid	12810069
PTEN	10q23del \| BZS \| MGC11227 \| MHAM \| MMAC1 \| PTEN1 \| TEP1	磷酸酶和长素同源物	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	15205473
RAC3	-	与RAS相关的C3肉毒纤维毒素底物3（RHO家族，小GTP结合蛋白RAC3）	-	HPRD	11747336
RAD9A	RAD9	RAD9 homolog A (S. pombe)	Two-hybrid	Biogrid	14966297
RAF1	克拉夫\|NS5 \|RAF-1 \|C-Raf	v-raf-1 murine leukemia viral oncogene homolog 1	-	HPRD,BioGRID	8349631
RAN	arA24 \| Gsp1 \| TC4	RAN，RAS成员Ras Oncogene家族	-	HPRD,BioGRID	10400640
RANBP9	RANBPM	RAN binding protein 9	-	HPRD,BioGRID	12361945
RB1	OSRC \|RB \|P105-RB \|PRB \|PP110	retinoblastoma 1	RB与AR相互作用。	BIND	9675141
RB1	OSRC \|RB \|P105-RB \|PRB \|PP110	retinoblastoma 1	-	HPRD,BioGRID	9675141
RCHY1	arNIP \| CHIMP \| DKFZp586C1620 \| PIRH2 \| PRO1996 \| RNF199 \| ZNF363 \| hARNIP	ring finger and CHY zinc finger domain containing 1	-	HPRD,BioGRID	12200228
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	-	HPRD	8798655
RNF14	arA54 \| FLJ26004 \| HFB30 \| HRIHFB2038 \| TRIAD2	环手指蛋白14	-	HPRD,BioGRID	10085091
RNF4	Res4-26 \|鼻烟	环手指蛋白4	-	HPRD,BioGRID	9710597\|10617653 \|11719514
SART3	DSAP1 \| KIAA0156 \| MGC138188 \| P100 \| RP11-13G14 \| TIP110 \| p110 \| p110(nrb)	squamous cell carcinoma antigen recognized by T cells 3	-	HPRD,BioGRID	15031286
SELENBP1	FLJ13813 \| LPSB \| SP56 \| hSBP \| hSP56	selenium binding protein 1	亲和力捕获 - 韦斯特恩	Biogrid	1540595
SLC25A4	AAC1 \| ANT \| ANT1 \| PEO2 \| PEO3 \| T1	溶质载体家族25（线粒体载体；腺嘌呤核苷酸转运剂），成员4	-	HPRD	12039962
SMAD3	DKFZp586N0721 \| DKFZp686J10186 \| HSPC193 \| HsT17436 \| JV15-2 \| MADH3 \| MGC60396	SMAD family member 3	-	HPRD,BioGRID	11280774
SMAD4	DPC4 \| JIP \| MADH4	SMAD family member 4	-	HPRD,BioGRID	12226080
SMARCA4	BAF190 \| BRG1 \| FLJ39786 \| SNF2 \| SNF2-BETA \| SNF2L4 \| SNF2LB \| SWI2 \| hSNF2b	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	亲和力捕获 - 韦斯特恩	Biogrid	14966121
SMARCC1	BAF155 \|cracc1 \|RSC8 \|srg3 \|SWI3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	亲和力捕获 - 韦斯特恩	Biogrid	14966121
SP1	-	Sp1 transcription factor	亲和力捕获 - 韦斯特恩	Biogrid	15661808
SPDEF	PDEF \|RP11-375E1__A.3 \|BA375E1.3	SAM pointed domain containing ets transcription factor	-	HPRD,BioGRID	10625666
SRC	ASV \| SRC1 \| c-SRC \| p60-Src	V-SRC肉瘤（Schmidt-Ruppin A-2）病毒癌基因同源物（Avian）	亲和力捕获 - 韦斯特恩 Two-hybrid	Biogrid	11032808\|15027889 \|15466214
SRY	TDF \| TDY	sex determining region Y	-	HPRD,BioGRID	11585838
Stat3	APRF \| FLJ20882 \| HIES \| MGC16063	转录3的信号换能器和激活因子（急性相反应因子）	-	HPRD,BioGRID	11751884
SVIL	DKFZp686A17191	Supervillin	-	HPRD,BioGRID	11792840
TBP	GTF2D \| GTF2D1 \| MGC117320 \| MGC126054 \| MGC126055 \| SCA17 \| TFIID	TATA box binding protein	重构的复合物	Biogrid	9238003
TCF4	E2-2 \| ITF2 \| MGC149723 \| MGC149724 \|甲状旁腺素\| SEF2\|SEF2-1 \| SEF2-1A \| SEF2-1B \| bHLHb19	transcription factor 4	-	HPRD,BioGRID	12799378
TDG	-	胸腺氨酸-DNA糖基酶	重构的复合物	Biogrid	12874288
TGFB1I1	arA55 \| HIC-5 \| HIC5 \| TSC-5	转化生长因子β1诱导的转录本1	-	HPRD	11155740
TGFB1I1	arA55 \| HIC-5 \| HIC5 \| TSC-5	转化生长因子β1诱导的转录本1	The carboxy terminus of ARA55 interacts with the carboxy terminus AR to enhance transcriptional activity.	BIND	10075738
TGFB1I1	arA55 \| HIC-5 \| HIC5 \| TSC-5	转化生长因子β1诱导的转录本1	亲和力捕获 - 韦斯特恩 Protein-peptide 重构的复合物 Two-hybrid	Biogrid	11779876\|11856738
TMF1	arA160	TATA element modulatory factor 1	Far Western 重构的复合物 Two-hybrid	Biogrid	10428808
TMF1	arA160	TATA element modulatory factor 1	-	HPRD	12165860
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	生化活动表型抑制	Biogrid	11504717
TRIM24	PTC6 \|RNF82 \|TF1A \|tif1 \|tif1a \|tif1alpha \|HTIF1	tripartite motif-containing 24	-	HPRD,BioGRID	9115274
TSG101	TSG10 \| VPS23	tumor susceptibility gene 101	-	HPRD,BioGRID	10508170
UBE2I	C358B7.1 \| P18 \| UBC9	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	亲和力捕获 - 韦斯特恩 Phenotypic Enhancement Two-hybrid	Biogrid	10383460
UBE2I	C358B7.1 \| P18 \| UBC9	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	-	HPRD	8798622
UXT	arT-27	ubiquitously-expressed transcript	-	HPRD,BioGRID	11854421
XRCC5	FLJ39089 \| KARP-1 \| KARP1 \| KU80 \| KUB2 \| Ku86 \| NFIV	X射线修复补充中国仓鼠细胞5（双链破裂的重新加入）中的缺陷修复	重构的复合物	Biogrid	15640154
XRCC6	CTC75 \| CTCBF \| G22P1 \| KU70 \| ML8 \| TLAA	X-ray repair complementing defective repair in Chinese hamster cells 6	亲和力捕获 - 韦斯特恩	Biogrid	15640154
YWHAQ	14-3-3 \| 1C5 \| HS1	酪氨酸3-单加氧酶/色氨酸5-单加氧酶激活蛋白，theta多肽	重构的复合物	Biogrid	11266503
ZMIZ1	FLJ13541 \| KIAA1224 \| MIZ \| RAI17 \| Zimp10 \| hZIMP10	zinc finger, MIZ-type containing 1	-	HPRD,BioGRID	14609956

Section V. Pathway annotation

Pathway name	路径大小	# SZGR 2.0 genes in pathway	信息
Kegg卵母细胞减数分裂	114	79	All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER	328	259	All SZGR 2.0 genes in this pathway
KEGG PROSTATE CANCER	89	75	All SZGR 2.0 genes in this pathway
ST ADRENERGIC	36	29	All SZGR 2.0 genes in this pathway
PID SMAD2 3核途径	82	63	All SZGR 2.0 genes in this pathway
PID AR PATHWAY	61	46	All SZGR 2.0 genes in this pathway
PID AR TF PATHWAY	53	38	All SZGR 2.0 genes in this pathway
PID AR NONGENOMIC PATHWAY	31	27	All SZGR 2.0 genes in this pathway
PID BETA CATENIN NUC PATHWAY	80	60	All SZGR 2.0 genes in this pathway
PID HNF3A PATHWAY	44	29	All SZGR 2.0 genes in this pathway
PID HES HEY PATHWAY	48	39	All SZGR 2.0 genes in this pathway
REACTOME GENERIC TRANSCRIPTION PATHWAY	352	181	All SZGR 2.0 genes in this pathway
REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	49	36	All SZGR 2.0 genes in this pathway
CHEMNITZ RESPONSE TO PROSTAGLANDIN E2 DN	391	222	All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS TOP50 UP	38	27	All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS BASAL UP	380	215	All SZGR 2.0 genes in this pathway
多恩乳腺癌课程	72	38	All SZGR 2.0 genes in this pathway
DOANE BREAST CANCER ESR1 UP	112	72	All SZGR 2.0 genes in this pathway
甲状腺癌的Rodrigues分化不佳的DN	805	505	All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN	781	465	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP	293	179	All SZGR 2.0 genes in this pathway
CHEBOTAEV GR TARGETS DN	120	73	All SZGR 2.0 genes in this pathway
OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP DN	35	20	All SZGR 2.0 genes in this pathway
RIZ ERYTHROID DIFFERENTIATION 12HR	43	35	All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 3	48	31	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS LUMINAL	326	213	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS BASAL	330	217	All SZGR 2.0 genes in this pathway
农民乳腺癌基础与仙女	330	215	All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER CLUSTER 7	20	11	All SZGR 2.0 genes in this pathway
LIEN BREAST CARCINOMA METAPLASTIC VS DUCTAL DN	114	58	All SZGR 2.0 genes in this pathway
Mohankumar TLX1靶向	414	287	All SZGR 2.0 genes in this pathway
YANG BREAST CANCER ESR1 LASER UP	34	25	All SZGR 2.0 genes in this pathway
Pujana乳腺癌点燃int网络	101	73	All SZGR 2.0 genes in this pathway
KHETCHOUMIAN TRIM24 TARGETS DN	8	7	All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN	428	306	All SZGR 2.0 genes in this pathway
CHANG IMMORTALIZED BY HPV31 DN	65	45	All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE UP	244	165	All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 48HR DN	504	323	All SZGR 2.0 genes in this pathway
Zhu CMV 8小时DN	53	40	All SZGR 2.0 genes in this pathway
ZHU CMV ALL DN	128	93	All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 UP	428	266	All SZGR 2.0 genes in this pathway
Mahajan对IL1A的回应	81	52	All SZGR 2.0 genes in this pathway
霍林引用1个目标1 dn	37	22	All SZGR 2.0 genes in this pathway
LEIN MEDULLA MARKERS	81	48	All SZGR 2.0 genes in this pathway
GAVIN FOXP3 TARGETS CLUSTER P6	91	44	All SZGR 2.0 genes in this pathway
Massarweh tamoxifen抗性	578	341	All SZGR 2.0 genes in this pathway
Ouyang前列腺癌标记	19	16	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER RELAPSE IN BRAIN DN	85	58	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER ERBB2 UP	147	83	All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN	701	446	All SZGR 2.0 genes in this pathway
Izadpanah干细胞脂肪与骨DN	108	68	All SZGR 2.0 genes in this pathway
MATZUK MALE REPRODUCTION SERTOLI	28	23	All SZGR 2.0 genes in this pathway
李肝癌的生存	185	112	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 UP	176	110	All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN	179	97	All SZGR 2.0 genes in this pathway
Hoshida肝癌生存DN	113	76	All SZGR 2.0 genes in this pathway
YAGI AML WITH INV 16 TRANSLOCATION	422	277	All SZGR 2.0 genes in this pathway
LI PROSTATE CANCER EPIGENETIC	30	22	All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES DN	210	141	All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS UP	221	135	All SZGR 2.0 genes in this pathway
PANGAS TUMOR SUPPRESSION BY SMAD1 AND SMAD5 UP	134	85	All SZGR 2.0 genes in this pathway
SUBTIL PROGESTIN TARGETS	36	25	All SZGR 2.0 genes in this pathway
CHANGOLKAR H2AFY TARGETS DN	40	26	All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS UP	745	475	All SZGR 2.0 genes in this pathway
WANG MLL TARGETS	289	188	All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 1ST EGF PULSE ONLY	1839	928	All SZGR 2.0 genes in this pathway
ZWANG EGF INTERVAL DN	214	124	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	mirna seq
miRNA family	UTR开始	UTR结束	匹配方法	miRNA ID	mirna seq
miR-130/301	71	77	1A	hsa-miR-130a^brain	CAGUGCAAUGUUAAAAGGGCAU
				hsa-miR-301	cagugcaauaugucaaagc
				hsa-miR-130b^brain	CAGUGCAAUGAUGAAAGGGCAU
				hsa-miR-454-3p	UAGUGCAAUAUUGCUUAUAGGGUUU
mir-493-5p	113	119	m8	HSA-MIR-493-5p	UUGUACAUGGUAGGCUUUCAUU

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click这里to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click这里查看与大脑相关的miRNA列表。

Gene Page:ar