Gene Page:LCK
Summary?
| GeneID | 3932 |
| Symbol | LCK |
| Synonyms | IMD22|LSK|YT16|p56lck|pp58lck |
| Description | LCK proto-oncogene, Src family tyrosine kinase |
| Reference | MIM:153390|HGNC:HGNC:6524|Ensembl:ENSG00000182866|HPRD:01080|Vega:OTTHUMG00000007463 |
| Gene type | protein-coding |
| Map location | 1p34.3 |
| Pascal p-value | 0.207 |
| Fetal beta | 0.136 |
| DMG | 1 (# studies) |
| eGene | Cerebellum Myers' cis & trans |
| Support | G2Cdb.humanPSD G2Cdb.humanPSP |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| DMG:vanEijk_2014 | Genome-wide DNA methylation analysis | This dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250). | 2 |
| PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
Differentially methylated gene
Differentially methylated gene| Probe | Chromosome | Position | Nearest gene | P (dis) | Beta (dis) | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| cg06397510 | 1 | 32403634 | LCK | 0.002 | 4.574 | DMG:vanEijk_2014 | |
| cg21172540 | 1 | 32827840 | LCK | 0.001 | 4.196 | DMG:vanEijk_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs3924767 | chr2 | 228922592 | LCK | 3932 | 0.1 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PPP1R14A | 0.53 | 0.43 |
| TFPT | 0.51 | 0.35 |
| PSMB10 | 0.50 | 0.38 |
| IFI27L2 | 0.49 | 0.39 |
| SELM | 0.49 | 0.35 |
| TMEM141 | 0.49 | 0.36 |
| MYL3 | 0.49 | 0.42 |
| C12orf62 | 0.49 | 0.37 |
| KB-1839H6.1 | 0.48 | 0.37 |
| CHCHD10 | 0.48 | 0.37 |
| 十大负面中的基因 | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PCDHB10 | -0.38 | -0.44 |
| RNF40 | -0.38 | -0.42 |
| SF3B2 | -0.37 | -0.41 |
| ZFP28 | -0.37 | -0.41 |
| CDC2L2 | -0.36 | -0.38 |
| PCDHB6 | -0.36 | -0.39 |
| C16orf88 | -0.36 | -0.40 |
| EWSR1 | -0.36 | -0.44 |
| DHX57 | -0.36 | -0.45 |
| BLMH | -0.36 | -0.42 |
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| ADAM10 | AD10 | CD156c | HsT18717 | MADM | kuz | ADAM metallopeptidase domain 10 | Affinity Capture-Western | BioGRID | 11741929 |
| ADAM15 | MDC15 | ADAM metallopeptidase domain 15 | - | HPRD,BioGRID | 11741929 |
| ARHGAP17 | DKFZp564A1363 | FLJ37567 | FLJ43368 | MGC87805 | MST066 | MST110 | MSTP038 | MSTP066 | MSTP110 | NADRIN | RICH1 | WBP15 | Rho GTPase activating protein 17 | Reconstituted Complex | BioGRID | 11431473 |
| AXL | JTK11 | UFO | AXL receptor tyrosine kinase | - | HPRD,BioGRID | 9178760 |
| BCAR1 | CAS | CAS1 | CASS1 | CRKAS | P130Cas | breast cancer anti-estrogen resistance 1 | - | HPRD,BioGRID | 9020138 |
| CBL | C-CBL | CBL2 | RNF55 | Cas-Br-M (murine) ecotropic retroviral transforming sequence | - | HPRD,BioGRID | 9178909|11741956 |11904433 |
| CCR5 | CC-CKR-5 | CCCKR5 | CD195 | CKR-5 | CKR5 | CMKBR5 | chemokine (C-C motif) receptor 5 | - | HPRD | 11591716 |
| CD2 | SRBC | T11 | CD2 molecule | - | HPRD,BioGRID | 8551220 |
| CD28 | MGC138290 | Tp44 | CD28 molecule | - | HPRD | 10430626 |
| CD38 | T10 | CD38 molecule | - | HPRD | 10636863 |
| CD3E | FLJ18683 | T3E | TCRE | CD3e molecule, epsilon (CD3-TCR complex) | - | HPRD | 11855827 |
| CD4 | CD4mut | CD4 molecule | - | HPRD,BioGRID | 11854499 |
| CD44 | CDW44 | CSPG8 | ECMR-III | HCELL | IN | LHR | MC56 | MDU2 | MDU3 | MGC10468 | MIC4 | MUTCH-I | Pgp1 | CD44 molecule (Indian blood group) | - | HPRD,BioGRID | 8576267 |
| CD48 | BCM1 | BLAST | BLAST1 | MEM-102 | SLAMF2 | hCD48 | mCD48 | CD48 molecule | - | HPRD,BioGRID | 12007789 |
| CD5 | LEU1 | T1 | CD5 molecule | - | HPRD | 7513045 |
| CD55 | CR | CROM | DAF | TC | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | - | HPRD | 1385527 |
| CD8B | CD8B1 | LYT3 | Leu2 | Ly3 | MGC119115 | CD8b molecule | CD8-Beta interacts with Lck. | BIND | 15980863 |
| CDC25C | CDC25 | cell division cycle 25 homolog C (S. pombe) | - | HPRD,BioGRID | 11389730 |
| CTLA4 | CD152 | CELIAC3 | CTLA-4 | GSE | IDDM12 | cytotoxic T-lymphocyte-associated protein 4 | - | HPRD,BioGRID | 9712716 |
| CTNND1 | CAS | CTNND | KIAA0384 | P120CAS | P120CTN | p120 | catenin (cadherin-associated protein), delta 1 | Biochemical Activity | BioGRID | 12835311 |
| CTNND2 | GT24 | NPRAP | catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | - | HPRD | 12835311 |
| DLG1 | DKFZp761P0818 | DKFZp781B0426 | DLGH1 | SAP97 | dJ1061C18.1.1 | hdlg | discs, large homolog 1 (Drosophila) | - | HPRD,BioGRID | 9341123 |
| DNM2 | CMTDI1 | CMTDIB | DI-CMTB | DYN2 | DYNII | dynamin 2 | An unspecified isoform of Dyn2 interacts with Lck. This interaction was modeled on a demonstrated interaction between human Dyn2 and Lck from an unspecified species. | BIND | 15696170 |
| DOK2 | p56DOK | p56dok-2 | docking protein 2, 56kDa | - | HPRD | 10799545 |
| DOK3 | DOKL | FLJ22570 | FLJ39939 | docking protein 3 | - | HPRD | 10733577 |
| FAS | ALPS1A | APO-1 | APT1 | CD95 | FAS1 | FASTM | TNFRSF6 | Fas (TNF receptor superfamily, member 6) | - | HPRD,BioGRID | 8864141 |
| FASLG | APT1LG1 | CD178 | CD95L | FASL | TNFSF6 | Fas ligand (TNF superfamily, member 6) | - | HPRD,BioGRID | 11741599 |
| FCGR3A | CD16 | CD16A | FCG3 | FCGR3 | FCGRIII | FCR-10 | FCRIII | FCRIIIA | IGFR3 | Fc fragment of IgG, low affinity IIIa, receptor (CD16a) | - | HPRD | 8258691 |
| IL2RB | CD122 | P70-75 | interleukin 2 receptor, beta | - | HPRD,BioGRID | 2047859 |
| JAK3 | JAK-3 | JAK3_HUMAN | JAKL | L-JAK | LJAK | Janus kinase 3 (a protein tyrosine kinase, leukocyte) | - | HPRD | 11278738 |
| KHDRBS1 | FLJ34027 | Sam68 | p62 | KH domain containing, RNA binding, signal transduction associated 1 | - | HPRD,BioGRID | 9045636 |
| KHDRBS1 | FLJ34027 | Sam68 | p62 | KH domain containing, RNA binding, signal transduction associated 1 | Lck interacts with Sam68. | BIND | 11278465 |
| KIT | C-Kit | CD117 | PBT | SCFR | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | - | HPRD,BioGRID | 9788619 |
| MS4A1 | B1 | Bp35 | CD20 | LEU-16 | MGC3969 | MS4A2 | S7 | membrane-spanning 4-domains, subfamily A, member 1 | Affinity Capture-Western | BioGRID | 7545683 |
| NEDD9 | CAS-L | CAS2 | CASL | CASS2 | HEF1 | dJ49G10.2 | dJ761I2.1 | neural precursor cell expressed, developmentally down-regulated 9 | - | HPRD,BioGRID | 8879209 |
| NFKBIA | IKBA | MAD-3 | NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | LCK interacts with and phosphorylates NFKBIA (I-kappa-B-alpha). This interaction was modeled on a demonstrated interaction between LCK from an unspecified species and human NFKBIA. | BIND | 14534291 |
| NOTCH1 | TAN1 | hN1 | Notch homolog 1, translocation-associated (Drosophila) | - | HPRD,BioGRID | 14583609 |
| NR2F2 | ARP1 | COUP-TFII | COUPTFB | MGC117452 | SVP40 | TFCOUP2 | nuclear receptor subfamily 2, group F, member 2 | Reconstituted Complex Two-hybrid |
BioGRID | 8910285 |
| PAG1 | CBP | FLJ37858 | MGC138364 | PAG | phosphoprotein associated with glycosphingolipid microdomains 1 | - | HPRD,BioGRID | 10790433 |
| PECAM1 | CD31 | PECAM-1 | platelet/endothelial cell adhesion molecule | - | HPRD,BioGRID | 9624175 |
| PI4KA | FLJ16556 | PI4K-ALPHA | PIK4CA | pi4K230 | phosphatidylinositol 4-kinase, catalytic, alpha | Reconstituted Complex | BioGRID | 8246987 |
| PIK3CA | MGC142161 | MGC142163 | PI3K | p110-alpha | phosphoinositide-3-kinase, catalytic, alpha polypeptide | - | HPRD,BioGRID | 8020561 |
| PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | - | HPRD | 7504174 |
| PIK3R1 | GRB1 | p85 | p85-ALPHA | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | Reconstituted Complex | BioGRID | 8294442 |
| PLCG1 | PLC-II | PLC1 | PLC148 | PLCgamma1 | phospholipase C, gamma 1 | - | HPRD | 1500851 |
| PLD2 | - | phospholipase D2 | - | HPRD | 12697812 |
| PRKCQ | MGC126514 | MGC141919 | PRKCT | nPKC-theta | protein kinase C, theta | Two-hybrid | BioGRID | 10383400 |
| PTK2B | CADTK | CAKB | FADK2 | FAK2 | FRNK | PKB | PTK | PYK2 | RAFTK | PTK2B protein tyrosine kinase 2 beta | - | HPRD,BioGRID | 9091579 |
| PTPN11 | BPTP3 | CFC | MGC14433 | NS1 | PTP-1D | PTP2C | SH-PTP2 | SH-PTP3 | SHP2 | protein tyrosine phosphatase, non-receptor type 11 | - | HPRD | 10617656 |
| PTPN6 | HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1 | 蛋白质酪氨酸磷酸酶,non-receptor类型6 | - | HPRD | 8114715|11294838 |
| PTPN6 | HCP | HCPH | HPTP1C | PTP-1C | SH-PTP1 | SHP-1 | SHP-1L | SHP1 | 蛋白质酪氨酸磷酸酶,non-receptor类型6 | Biochemical Activity in vitro in vivo |
BioGRID | 8114715|10617656 |11294838 |
| PTPRC | B220 | CD45 | CD45R | GP180 | LCA | LY5 | T200 | protein tyrosine phosphatase, receptor type, C | - | HPRD,BioGRID | 8473339|8576115 |
| PXN | FLJ16691 | paxillin | - | HPRD,BioGRID | 9488700 |
| RAF1 | CRAF | NS5 | Raf-1 | c-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 | - | HPRD,BioGRID | 8939988 |
| SH2B3 | CELIAC13 | LNK | SH2B adaptor protein 3 | - | HPRD,BioGRID | 10799879 |
| SIT1 | MGC125908 | MGC125909 | MGC125910 | RP11-331F9.5 | SIT | signaling threshold regulating transmembrane adaptor 1 | - | HPRD,BioGRID | 10209036 |
| SKAP1 | SCAP1 | SKAP55 | src kinase associated phosphoprotein 1 | - | HPRD,BioGRID | 9195899 |
| SQSTM1 | A170 | OSIL | PDB3 | ZIP3 | p60 | p62 | p62B | sequestosome 1 | - | HPRD,BioGRID | 8650207 |
| STAT3 | APRF | FLJ20882 | HIES | MGC16063 | signal transducer and activator of transcription 3 (acute-phase response factor) | - | HPRD | 10825200 |
| SYK | DKFZp313N1010 | FLJ25043 | FLJ37489 | spleen tyrosine kinase | - | HPRD,BioGRID | 7539035 |
| TEK | CD202B | TIE-2 | TIE2 | VMCM | VMCM1 | TEK tyrosine kinase, endothelial | - | HPRD | 7545683 |
| THY1 | CD90 | FLJ33325 | Thy-1 cell surface antigen | - | HPRD,BioGRID | 1351058 |
| TRAT1 | HSPC062 | TCRIM | TRIM | T cell receptor associated transmembrane adaptor 1 | Reconstituted Complex | BioGRID | 10790433 |
| TRPV4 | OTRPC4 | TRP12 | VR-OAC | VRL-2 | VRL2 | VROAC | transient receptor potential cation channel, subfamily V, member 4 | - | HPRD,BioGRID | 12538589 |
| TUB | rd5 | tubby homolog (mouse) | - | HPRD | 10455176 |
| UBE3A | ANCR | AS | E6-AP | EPVE6AP | FLJ26981 | HPVE6A | ubiquitin protein ligase E3A | Reconstituted Complex Two-hybrid |
BioGRID | 10449731 |
| UNC119 | HRG4 | unc-119 homolog (C. elegans) | - | HPRD,BioGRID | 14757743 |
| ZAP70 | FLJ17670 | FLJ17679 | SRK | STD | TZK | ZAP-70 | zeta-chain (TCR) associated protein kinase 70kDa | - | HPRD,BioGRID | 10318843 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY | 137 | 92 | All SZGR 2.0 genes in this pathway |
| KEGG T CELL RECEPTOR SIGNALING PATHWAY | 108 | 89 | All SZGR 2.0 genes in this pathway |
| KEGG PRIMARY IMMUNODEFICIENCY | 35 | 28 | All SZGR 2.0 genes in this pathway |
| BIOCARTA CSK PATHWAY | 24 | 20 | All SZGR 2.0 genes in this pathway |
| BIOCARTA IL2 PATHWAY | 22 | 16 | All SZGR 2.0 genes in this pathway |
| BIOCARTA IL7 PATHWAY | 17 | 14 | All SZGR 2.0 genes in this pathway |
| BIOCARTA TCRA PATHWAY | 13 | 10 | All SZGR 2.0 genes in this pathway |
| BIOCARTA TCR PATHWAY | 49 | 37 | All SZGR 2.0 genes in this pathway |
| BIOCARTA CTLA4 PATHWAY | 21 | 18 | All SZGR 2.0 genes in this pathway |
| ST T CELL SIGNAL TRANSDUCTION | 45 | 33 | All SZGR 2.0 genes in this pathway |
| PID NFKAPPAB ATYPICAL PATHWAY | 17 | 15 | All SZGR 2.0 genes in this pathway |
| PID GLYPICAN 1PATHWAY | 27 | 20 | All SZGR 2.0 genes in this pathway |
| PID TCR PATHWAY | 66 | 51 | All SZGR 2.0 genes in this pathway |
| PID PTP1B PATHWAY | 52 | 40 | All SZGR 2.0 genes in this pathway |
| PID IL12 2PATHWAY | 63 | 54 | All SZGR 2.0 genes in this pathway |
| PID P38 ALPHA BETA PATHWAY | 31 | 25 | All SZGR 2.0 genes in this pathway |
| PID CD8 TCR PATHWAY | 53 | 42 | All SZGR 2.0 genes in this pathway |
| PID TXA2PATHWAY | 57 | 43 | All SZGR 2.0 genes in this pathway |
| PID SHP2 PATHWAY | 58 | 46 | All SZGR 2.0 genes in this pathway |
| PID IL2 1PATHWAY | 55 | 43 | All SZGR 2.0 genes in this pathway |
| PID CXCR4 PATHWAY | 102 | 78 | All SZGR 2.0 genes in this pathway |
| PID PI3KCI PATHWAY | 49 | 40 | All SZGR 2.0 genes in this pathway |
| PID IL2 PI3KPATHWAY | 34 | 27 | All SZGR 2.0 genes in this pathway |
| PID AMB2中性粒细胞ROPHILS PATHWAY | 41 | 32 | All SZGR 2.0 genes in this pathway |
| PID EPHA FWDPATHWAY | 34 | 29 | All SZGR 2.0 genes in this pathway |
| PID PDGFRB PATHWAY | 129 | 103 | All SZGR 2.0 genes in this pathway |
| PID IL2 STAT5 PATHWAY | 30 | 23 | All SZGR 2.0 genes in this pathway |
| PID EPHRINB REV PATHWAY | 30 | 25 | All SZGR 2.0 genes in this pathway |
| PID ALPHA SYNUCLEIN PATHWAY | 33 | 25 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY SCF KIT | 78 | 59 | All SZGR 2.0 genes in this pathway |
| REACTOME REGULATION OF KIT SIGNALING | 17 | 10 | All SZGR 2.0 genes in this pathway |
| REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS | 21 | 12 | All SZGR 2.0 genes in this pathway |
| REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL | 91 | 65 | All SZGR 2.0 genes in this pathway |
| REACTOME PECAM1 INTERACTIONS | 10 | 7 | All SZGR 2.0 genes in this pathway |
| REACTOME TCR SIGNALING | 54 | 46 | All SZGR 2.0 genes in this pathway |
| REACTOME DOWNSTREAM TCR SIGNALING | 37 | 32 | All SZGR 2.0 genes in this pathway |
| REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | 16 | 15 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | 14 | 14 | All SZGR 2.0 genes in this pathway |
| REACTOME GENERATION OF SECOND MESSENGER MOLECULES | 27 | 25 | All SZGR 2.0 genes in this pathway |
| REACTOME GPVI MEDIATED ACTIVATION CASCADE | 31 | 25 | All SZGR 2.0 genes in this pathway |
| REACTOME CD28 CO STIMULATION | 32 | 26 | All SZGR 2.0 genes in this pathway |
| REACTOME CD28 DEPENDENT VAV1 PATHWAY | 11 | 10 | All SZGR 2.0 genes in this pathway |
| REACTOME PD1 SIGNALING | 18 | 14 | All SZGR 2.0 genes in this pathway |
| REACTOME COSTIMULATION BY THE CD28 FAMILY | 63 | 48 | All SZGR 2.0 genes in this pathway |
| REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | 22 | 18 | All SZGR 2.0 genes in this pathway |
| REACTOME CTLA4 INHIBITORY SIGNALING | 21 | 15 | All SZGR 2.0 genes in this pathway |
| REACTOME SIGNALING BY ILS | 107 | 86 | All SZGR 2.0 genes in this pathway |
| REACTOME IL 2 SIGNALING | 41 | 34 | All SZGR 2.0 genes in this pathway |
| REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
| REACTOME HIV INFECTION | 207 | 122 | All SZGR 2.0 genes in this pathway |
| REACTOME HOST INTERACTIONS OF HIV FACTORS | 132 | 81 | All SZGR 2.0 genes in this pathway |
| REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS | 28 | 19 | All SZGR 2.0 genes in this pathway |
| REACTOME IMMUNE SYSTEM | 933 | 616 | All SZGR 2.0 genes in this pathway |
| REACTOME ADAPTIVE IMMUNE SYSTEM | 539 | 350 | All SZGR 2.0 genes in this pathway |
| REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 270 | 204 | All SZGR 2.0 genes in this pathway |
| REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 208 | 138 | All SZGR 2.0 genes in this pathway |
| HOLLMANN APOPTOSIS VIA CD40 UP | 201 | 125 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS UP | 473 | 314 | All SZGR 2.0 genes in this pathway |
| JAATINEN HEMATOPOIETIC STEM CELL DN | 226 | 132 | All SZGR 2.0 genes in this pathway |
| PROVENZANI METASTASIS UP | 194 | 112 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION DN | 234 | 147 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 3 4WK DN | 39 | 27 | All SZGR 2.0 genes in this pathway |
| MCBRYAN PUBERTAL BREAST 6 7WK UP | 197 | 135 | All SZGR 2.0 genes in this pathway |
| MCBRYAN TERMINAL END BUD DN | 7 | 6 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| LINDGREN BLADDER CANCER CLUSTER 2B | 392 | 251 | All SZGR 2.0 genes in this pathway |
| SCHLOSSER SERUM RESPONSE AUGMENTED BY MYC | 108 | 74 | All SZGR 2.0 genes in this pathway |
| FARMER BREAST CANCER CLUSTER 1 | 44 | 23 | All SZGR 2.0 genes in this pathway |
| HATADA METHYLATED IN LUNG CANCER UP | 390 | 236 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA2 PCC NETWORK | 423 | 265 | All SZGR 2.0 genes in this pathway |
| PUJANA CHEK2 PCC NETWORK | 779 | 480 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES 1 | 379 | 235 | All SZGR 2.0 genes in this pathway |
| SHIN B CELL LYMPHOMA CLUSTER 3 | 28 | 23 | All SZGR 2.0 genes in this pathway |
| FERRANDO TAL1 NEIGHBORS | 21 | 15 | All SZGR 2.0 genes in this pathway |
| PENG LEUCINE DEPRIVATION UP | 142 | 93 | All SZGR 2.0 genes in this pathway |
| FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK UP | 87 | 58 | All SZGR 2.0 genes in this pathway |
| PEART HDAC PROLIFERATION CLUSTER DN | 76 | 57 | All SZGR 2.0 genes in this pathway |
| CHIARETTI ACUTE LYMPHOBLASTIC LEUKEMIA ZAP70 | 67 | 33 | All SZGR 2.0 genes in this pathway |
| KUMAR TARGETS OF MLL AF9 FUSION | 405 | 264 | All SZGR 2.0 genes in this pathway |
| SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 | 419 | 273 | All SZGR 2.0 genes in this pathway |
| GAVIN FOXP3 TARGETS CLUSTER P2 | 79 | 55 | All SZGR 2.0 genes in this pathway |
| FOSTER TOLERANT MACROPHAGE DN | 409 | 268 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY 4NQO IN OLD | 13 | 10 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY 4NQO IN WS | 40 | 26 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY GAMMA IN OLD | 31 | 19 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY GAMMA IN WS | 33 | 22 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE NOT BY UV IN WS | 12 | 9 | All SZGR 2.0 genes in this pathway |
| KYNG DNA DAMAGE DN | 195 | 135 | All SZGR 2.0 genes in this pathway |
| KYNG ENVIRONMENTAL STRESS RESPONSE UP | 56 | 41 | All SZGR 2.0 genes in this pathway |
| FINETTI BREAST CANCER KINOME GREEN | 16 | 14 | All SZGR 2.0 genes in this pathway |
| WALLACE PROSTATE CANCER RACE UP | 299 | 167 | All SZGR 2.0 genes in this pathway |
| WORSCHECH TUMOR REJECTION UP | 56 | 32 | All SZGR 2.0 genes in this pathway |
| MITSIADES RESPONSE TO APLIDIN UP | 439 | 257 | All SZGR 2.0 genes in this pathway |
| 乳腺癌萧述三腔的DN | 564 | 326 | All SZGR 2.0 genes in this pathway |
| SMID BREAST CANCER NORMAL LIKE UP | 476 | 285 | All SZGR 2.0 genes in this pathway |
| BHATI G2M ARREST BY 2METHOXYESTRADIOL DN | 127 | 75 | All SZGR 2.0 genes in this pathway |
| QI PLASMACYTOMA UP | 259 | 185 | All SZGR 2.0 genes in this pathway |
| MUELLER PLURINET | 299 | 189 | All SZGR 2.0 genes in this pathway |
| GRESHOCK CANCER COPY NUMBER UP | 323 | 240 | All SZGR 2.0 genes in this pathway |
| VILIMAS NOTCH1 TARGETS UP | 52 | 41 | All SZGR 2.0 genes in this pathway |
| ICHIBA GRAFT VERSUS HOST DISEASE 35D UP | 131 | 79 | All SZGR 2.0 genes in this pathway |
| LEE DIFFERENTIATING T LYMPHOCYTE | 200 | 115 | All SZGR 2.0 genes in this pathway |
| ZHAN LATE DIFFERENTIATION GENES DN | 16 | 10 | All SZGR 2.0 genes in this pathway |
| POOLA INVASIVE BREAST CANCER UP | 288 | 168 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES DN | 210 | 141 | All SZGR 2.0 genes in this pathway |
| GUTIERREZ CHRONIC LYMPHOCYTIC LEUKEMIA DN | 56 | 39 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 AND SATB1 UP | 87 | 52 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |