Gene Page:SNX19
Summary?
| GeneID | 399979 |
| Symbol | SNX19 |
| Synonyms | CHET8 |
| Description | sorting nexin 19 |
| Reference | HGNC:HGNC:21532|Ensembl:ENSG00000120451|HPRD:18621|Vega:OTTHUMG00000165663 |
| Gene type | protein-coding |
| 地图上的位置 | 11q25 |
| Pascal p-value | 4.331E-11 |
| Fetal beta | -0.175 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Meta |
Gene in Data Sources
| Gene set name | 基因的方法设置 | Description | Info |
|---|---|---|---|
| CV:GWAScat | Genome-wide Association Studies | This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb. | |
| CV:GWASdb | Genome-wide Association Studies | GWASdb records for schizophrenia | |
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| CV:Ripke_2013 | Genome-wide Association Study | Multi-stage GWAS, Sweden population and PGC2. 24 leading SNPs | |
| DNM:Guipponi_2014 | Whole Exome Sequencing analysis | 49 DNMs were identified by comparing the exome of 53 individuals with sporadic SCZ and of their non-affected parents | |
| LK:YES | Genome-wide Association Study | This data set included 99 genes mapped to the 22 regions. The 24 leading SNPs were also included in CV:Ripke_2013 | |
| PMID:cooccur | High-throughput literature-search | 系统的search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
| Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias | Click to show details |
Section I. Genetics and epigenetics annotation
DNM table
DNM table| Gene | Chromosome | Position | Ref | Alt | Transcript | AA change | Mutation type | Sift | CG46 | Trait | Study |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SNX19 | G | A | NM_014758 | p.E710K | missense | 0.22 | 0.42 | Schizophrenia | DNM:Guipponi_2014 |
eQTL annotation
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs10894268 | 11 | 130717153 | SNX19 | ENSG00000120451.6 | 1.588E-7 | 0 | 69251 | gtex_brain_ba24 |
| rs4366492 | 11 | 130717256 | SNX19 | ENSG00000120451.6 | 2.502E-7 | 0 | 69148 | gtex_brain_ba24 |
| rs1944142 | 11 | 130717440 | SNX19 | ENSG00000120451.6 | 2.943E-7 | 0 | 68964 | gtex_brain_ba24 |
| rs6590512 | 11 | 130717916 | SNX19 | ENSG00000120451.6 | 3.423E-7 | 0 | 68488 | gtex_brain_ba24 |
| rs398018089 | 11 | 130718226 | SNX19 | ENSG00000120451.6 | 3.176 e - | 0 | 68178 | gtex_brain_ba24 |
| rs10791097 | 11 | 130718630 | SNX19 | ENSG00000120451.6 | 2.502E-7 | 0 | 67774 | gtex_brain_ba24 |
| rs10791098 | 11 | 130718711 | SNX19 | ENSG00000120451.6 | 5.727E-7 | 0 | 67693 | gtex_brain_ba24 |
| rs10791099 | 11 | 130718813 | SNX19 | ENSG00000120451.6 | 5.727E-7 | 0 | 67591 | gtex_brain_ba24 |
| rs10750450 | 11 | 130719061 | SNX19 | ENSG00000120451.6 | 5.727E-7 | 0 | 67343 | gtex_brain_ba24 |
| rs67215852 | 11 | 130719075 | SNX19 | ENSG00000120451.6 | 2.514E-7 | 0 | 67329 | gtex_brain_ba24 |
| rs10894269 | 11 | 130722789 | SNX19 | ENSG00000120451.6 | 3.355E-7 | 0 | 63615 | gtex_brain_ba24 |
| rs4936120 | 11 | 130723452 | SNX19 | ENSG00000120451.6 | 3.355E-7 | 0 | 62952 | gtex_brain_ba24 |
| rs735094 | 11 | 130725109 | SNX19 | ENSG00000120451.6 | 1.465E-6 | 0 | 61295 | gtex_brain_ba24 |
| rs146063311 | 11 | 130726309 | SNX19 | ENSG00000120451.6 | 5.842E-7 | 0 | 60095 | gtex_brain_ba24 |
| rs10894270 | 11 | 130727212 | SNX19 | ENSG00000120451.6 | 1.499E-6 | 0 | 59192 | gtex_brain_ba24 |
| rs10894271 | 11 | 130727507 | SNX19 | ENSG00000120451.6 | 1.22E-6 | 0 | 58897 | gtex_brain_ba24 |
| rs78968418 | 11 | 130728056 | SNX19 | ENSG00000120451.6 | 3.355E-7 | 0 | 58348 | gtex_brain_ba24 |
| rs4601795 | 11 | 130729430 | SNX19 | ENSG00000120451.6 | 2.502E-7 | 0 | 56974 | gtex_brain_ba24 |
| rs4622274 | 11 | 130729486 | SNX19 | ENSG00000120451.6 | 1.465E-6 | 0 | 56918 | gtex_brain_ba24 |
| rs12284487 | 11 | 130729705 | SNX19 | ENSG00000120451.6 | 1.465E-6 | 0 | 56699 | gtex_brain_ba24 |
| rs12284540 | 11 | 130729772 | SNX19 | ENSG00000120451.6 | 1.465E-6 | 0 | 56632 | gtex_brain_ba24 |
| rs7116068 | 11 | 130732739 | SNX19 | ENSG00000120451.6 | 1.505E-7 | 0 | 53665 | gtex_brain_ba24 |
| rs7119425 | 11 | 130733185 | SNX19 | ENSG00000120451.6 | 3.199E-7 | 0 | 53219 | gtex_brain_ba24 |
| rs6590515 | 11 | 130733365 | SNX19 | ENSG00000120451.6 | 3.195E-7 | 0 | 53039 | gtex_brain_ba24 |
| rs6590516 | 11 | 130733393 | SNX19 | ENSG00000120451.6 | 3.193E-7 | 0 | 53011 | gtex_brain_ba24 |
| rs6590517 | 11 | 130733505 | SNX19 | ENSG00000120451.6 | 3.186E-7 | 0 | 52899 | gtex_brain_ba24 |
| rs6590518 | 11 | 130733530 | SNX19 | ENSG00000120451.6 | 3.186E-7 | 0 | 52874 | gtex_brain_ba24 |
| rs4936121 | 11 | 130733878 | SNX19 | ENSG00000120451.6 | 2.303E-7 | 0 | 52526 | gtex_brain_ba24 |
| rs4936122 | 11 | 130734264 | SNX19 | ENSG00000120451.6 | 1.512E-7 | 0 | 52140 | gtex_brain_ba24 |
| rs4937580 | 11 | 130734270 | SNX19 | ENSG00000120451.6 | 2.3E-7 | 0 | 52134 | gtex_brain_ba24 |
| rs2282579 | 11 | 130735482 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 50922 | gtex_brain_ba24 |
| rs2282578 | 11 | 130735691 | SNX19 | ENSG00000120451.6 | 1.572E-7 | 0 | 50713 | gtex_brain_ba24 |
| rs4411284 | 11 | 130738568 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 47836 | gtex_brain_ba24 |
| rs10791100 | 11 | 130738946 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 47458 | gtex_brain_ba24 |
| rs10791101 | 11 | 130739133 | SNX19 | ENSG00000120451.6 | 1.61E-7 | 0 | 47271 | gtex_brain_ba24 |
| rs2236711 | 11 | 130739284 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 47120 | gtex_brain_ba24 |
| rs2236717 | 11 | 130739887 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 46517 | gtex_brain_ba24 |
| rs2155358 | 11 | 130740357 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 46047 | gtex_brain_ba24 |
| rs4936123 | 11 | 130740967 | SNX19 | ENSG00000120451.6 | 6.059E-8 | 0 | 45437 | gtex_brain_ba24 |
| rs4937583 | 11 | 130741606 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 44798 | gtex_brain_ba24 |
| rs4937584 | 11 | 130741761 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 44643 | gtex_brain_ba24 |
| rs4937585 | 11 | 130741940 | SNX19 | ENSG00000120451.6 | 2.491E-7 | 0 | 44464 | gtex_brain_ba24 |
| rs10894273 | 11 | 130742155 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 44249 | gtex_brain_ba24 |
| rs1054869 | 11 | 130742630 | SNX19 | ENSG00000120451.6 | 2.329E-7 | 0 | 43774 | gtex_brain_ba24 |
| rs10160281 | 11 | 130742788 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 43616 | gtex_brain_ba24 |
| rs7125622 | 11 | 130743388 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 43016 | gtex_brain_ba24 |
| rs200755497 | 11 | 130743924 | SNX19 | ENSG00000120451.6 | 3.971E-7 | 0 | 42480 | gtex_brain_ba24 |
| rs11414920 | 11 | 130743925 | SNX19 | ENSG00000120451.6 | 2.347E-7 | 0 | 42479 | gtex_brain_ba24 |
| rs12363140 | 11 | 130744268 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 42136 | gtex_brain_ba24 |
| rs61910787 | 11 | 130744473 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41931 | gtex_brain_ba24 |
| rs12361892 | 11 | 130744490 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41914 | gtex_brain_ba24 |
| rs12363163 | 11 | 130744509 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41895 | gtex_brain_ba24 |
| rs11222369 | 11 | 130744670 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41734 | gtex_brain_ba24 |
| rs11222370 | 11 | 130744767 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41637 | gtex_brain_ba24 |
| rs10791102 | 11 | 130744977 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41427 | gtex_brain_ba24 |
| rs7926167 | 11 | 130745045 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 41359 | gtex_brain_ba24 |
| rs7940027 | 11 | 130745591 | SNX19 | ENSG00000120451.6 | 2.349E-7 | 0 | 40813 | gtex_brain_ba24 |
| rs11222371 | 11 | 130745719 | SNX19 | ENSG00000120451.6 | 1.615E-7 | 0 | 40685 | gtex_brain_ba24 |
| rs1050078 | 11 | 130746146 | SNX19 | ENSG00000120451.6 | 1.617E-7 | 0 | 40258 | gtex_brain_ba24 |
| rs1050071 | 11 | 130747231 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 39173 | gtex_brain_ba24 |
| rs6590520 | 11 | 130747386 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 39018 | gtex_brain_ba24 |
| rs3190331 | 11 | 130748131 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 38273 | gtex_brain_ba24 |
| rs12365680 | 11 | 130749059 | SNX19 | ENSG00000120451.6 | 1.617E-7 | 0 | 37345 | gtex_brain_ba24 |
| rs397799290 | 11 | 130749351 | SNX19 | ENSG00000120451.6 | 7.575E-8 | 0 | 37053 | gtex_brain_ba24 |
| rs2155749 | 11 | 130751094 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 35310 | gtex_brain_ba24 |
| rs2155750 | 11 | 130751261 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 35143 | gtex_brain_ba24 |
| rs7942621 | 11 | 130751308 | SNX19 | ENSG00000120451.6 | 2.321E-7 | 0 | 35096 | gtex_brain_ba24 |
| rs876641 | 11 | 130752040 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 34364 | gtex_brain_ba24 |
| rs3829271 | 11 | 130753912 | SNX19 | ENSG00000120451.6 | 4.155E-7 | 0 | 32492 | gtex_brain_ba24 |
| rs7103988 | 11 | 130754591 | SNX19 | ENSG00000120451.6 | 2.732E-7 | 0 | 31813 | gtex_brain_ba24 |
| rs4420278 | 11 | 130754785 | SNX19 | ENSG00000120451.6 | 5.297E-7 | 0 | 31619 | gtex_brain_ba24 |
| rs2155751 | 11 | 130755240 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 31164 | gtex_brain_ba24 |
| rs4457753 | 11 | 130755575 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30829 | gtex_brain_ba24 |
| rs201582106 | 11 | 130755664 | SNX19 | ENSG00000120451.6 | 3.366E-7 | 0 | 30740 | gtex_brain_ba24 |
| rs201248703 | 11 | 130755665 | SNX19 | ENSG00000120451.6 | 4.174E-7 | 0 | 30739 | gtex_brain_ba24 |
| rs4370948 | 11 | 130755700 | SNX19 | ENSG00000120451.6 | 8.99E-8 | 0 | 30704 | gtex_brain_ba24 |
| rs4436551 | 11 | 130755739 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30665 | gtex_brain_ba24 |
| rs4264159 | 11 | 130755784 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30620 | gtex_brain_ba24 |
| rs4456262 | 11 | 130755813 | SNX19 | ENSG00000120451.6 | 8.978 e-8 | 0 | 30591 | gtex_brain_ba24 |
| rs2155752 | 11 | 130755998 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30406 | gtex_brain_ba24 |
| rs4459316 | 11 | 130756176 | SNX19 | ENSG00000120451.6 | 4.874E-7 | 0 | 30228 | gtex_brain_ba24 |
| rs10894275 | 11 | 130756251 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30153 | gtex_brain_ba24 |
| rs1893017 | 11 | 130756253 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 30151 | gtex_brain_ba24 |
| rs1893018 | 11 | 130756632 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 29772 | gtex_brain_ba24 |
| rs1893019 | 11 | 130756664 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 29740 | gtex_brain_ba24 |
| rs10791103 | 11 | 130757161 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 29243 | gtex_brain_ba24 |
| rs7106973 | 11 | 130758113 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 28291 | gtex_brain_ba24 |
| rs7107595 | 11 | 130758556 | SNX19 | ENSG00000120451.6 | 2.348E-7 | 0 | 27848 | gtex_brain_ba24 |
| rs10750454 | 11 | 130764540 | SNX19 | ENSG00000120451.6 | 6.243E-8 | 0 | 21864 | gtex_brain_ba24 |
| rs10894279 | 11 | 130771768 | SNX19 | ENSG00000120451.6 | 1.399E-8 | 0 | 14636 | gtex_brain_ba24 |
| rs3751039 | 11 | 130773076 | SNX19 | ENSG00000120451.6 | 2.572E-8 | 0 | 13328 | gtex_brain_ba24 |
| rs7107568 | 11 | 130779668 | SNX19 | ENSG00000120451.6 | 4.747E-9 | 0 | 6736 | gtex_brain_ba24 |
| rs3751033 | 11 | 130786345 | SNX19 | ENSG00000120451.6 | 1.574E-8 | 0 | 59 | gtex_brain_ba24 |
| rs550355261 | 11 | 130786592 | SNX19 | ENSG00000120451.6 | 3.953E-10 | 0 | -188 | gtex_brain_ba24 |
| rs10894268 | 11 | 130717153 | SNX19 | ENSG00000120451.6 | 1.686E-8 | 0 | 69251 | gtex_brain_putamen_basal |
| rs4366492 | 11 | 130717256 | SNX19 | ENSG00000120451.6 | 2.661E-9 | 0 | 69148 | gtex_brain_putamen_basal |
| rs1944142 | 11 | 130717440 | SNX19 | ENSG00000120451.6 | 1.637E-8 | 0 | 68964 | gtex_brain_putamen_basal |
| rs6590512 | 11 | 130717916 | SNX19 | ENSG00000120451.6 | 1.793E-8 | 0 | 68488 | gtex_brain_putamen_basal |
| rs398018089 | 11 | 130718226 | SNX19 | ENSG00000120451.6 | 1.598E-9 | 0 | 68178 | gtex_brain_putamen_basal |
| rs10791097 | 11 | 130718630 | SNX19 | ENSG00000120451.6 | 2.661E-9 | 0 | 67774 | gtex_brain_putamen_basal |
| rs10791098 | 11 | 130718711 | SNX19 | ENSG00000120451.6 | 2.661E-9 | 0 | 67693 | gtex_brain_putamen_basal |
| rs10791099 | 11 | 130718813 | SNX19 | ENSG00000120451.6 | 2.661E-9 | 0 | 67591 | gtex_brain_putamen_basal |
| rs10750450 | 11 | 130719061 | SNX19 | ENSG00000120451.6 | 2.661E-9 | 0 | 67343 | gtex_brain_putamen_basal |
| rs67215852 | 11 | 130719075 | SNX19 | ENSG00000120451.6 | 1.102E-9 | 0 | 67329 | gtex_brain_putamen_basal |
| rs10894269 | 11 | 130722789 | SNX19 | ENSG00000120451.6 | 9.66E-7 | 0 | 63615 | gtex_brain_putamen_basal |
| rs4936120 | 11 | 130723452 | SNX19 | ENSG00000120451.6 | 9.66E-7 | 0 | 62952 | gtex_brain_putamen_basal |
| rs735094 | 11 | 130725109 | SNX19 | ENSG00000120451.6 | 2.238E-7 | 0 | 61295 | gtex_brain_putamen_basal |
| rs146905120 | 11 | 130726680 | SNX19 | ENSG00000120451.6 | 1.673E-6 | 0 | 59724 | gtex_brain_putamen_basal |
| rs10894271 | 11 | 130727507 | SNX19 | ENSG00000120451.6 | 1.609E-6 | 0 | 58897 | gtex_brain_putamen_basal |
| rs78968418 | 11 | 130728056 | SNX19 | ENSG00000120451.6 | 9.639E-7 | 0 | 58348 | gtex_brain_putamen_basal |
| rs4601795 | 11 | 130729430 | SNX19 | ENSG00000120451.6 | 3.42E-9 | 0 | 56974 | gtex_brain_putamen_basal |
| rs4622274 | 11 | 130729486 | SNX19 | ENSG00000120451.6 | 1.709E-7 | 0 | 56918 | gtex_brain_putamen_basal |
| rs12284487 | 11 | 130729705 | SNX19 | ENSG00000120451.6 | 1.709E-7 | 0 | 56699 | gtex_brain_putamen_basal |
| rs12284540 | 11 | 130729772 | SNX19 | ENSG00000120451.6 | 1.709E-7 | 0 | 56632 | gtex_brain_putamen_basal |
| rs11222358 | 11 | 130730497 | SNX19 | ENSG00000120451.6 | 1.706E-7 | 0 | 55907 | gtex_brain_putamen_basal |
| rs12286234 | 11 | 130730528 | SNX19 | ENSG00000120451.6 | 1.706E-7 | 0 | 55876 | gtex_brain_putamen_basal |
| rs12279359 | 11 | 130730544 | SNX19 | ENSG00000120451.6 | 1.706E-7 | 0 | 55860 | gtex_brain_putamen_basal |
| rs11222359 | 11 | 130730648 | SNX19 | ENSG00000120451.6 | 1.706E-7 | 0 | 55756 | gtex_brain_putamen_basal |
| rs200616753 | 11 | 130730716 | SNX19 | ENSG00000120451.6 | 3.326E-8 | 0 | 55688 | gtex_brain_putamen_basal |
| rs11222360 | 11 | 130730871 | SNX19 | ENSG00000120451.6 | 1.565E-7 | 0 | 55533 | gtex_brain_putamen_basal |
| rs10894272 | 11 | 130731081 | SNX19 | ENSG00000120451.6 | 1.501E-7 | 0 | 55323 | gtex_brain_putamen_basal |
| rs11222361 | 11 | 130731424 | SNX19 | ENSG00000120451.6 | 2.817E-8 | 0 | 54980 | gtex_brain_putamen_basal |
| rs11222362 | 11 | 130731425 | SNX19 | ENSG00000120451.6 | 3.069E-8 | 0 | 54979 | gtex_brain_putamen_basal |
| rs71882374 | 11 | 130731518 | SNX19 | ENSG00000120451.6 | 5.395E-9 | 0 | 54886 | gtex_brain_putamen_basal |
| rs7119425 | 11 | 130733185 | SNX19 | ENSG00000120451.6 | 6.992E-7 | 0 | 53219 | gtex_brain_putamen_basal |
| rs6590515 | 11 | 130733365 | SNX19 | ENSG00000120451.6 | 7.245E-7 | 0 | 53039 | gtex_brain_putamen_basal |
| rs6590516 | 11 | 130733393 | SNX19 | ENSG00000120451.6 | 7.34E-7 | 0 | 53011 | gtex_brain_putamen_basal |
| rs6590517 | 11 | 130733505 | SNX19 | ENSG00000120451.6 | 7.696E-7 | 0 | 52899 | gtex_brain_putamen_basal |
| rs6590518 | 11 | 130733530 | SNX19 | ENSG00000120451.6 | 7.839E-7 | 0 | 52874 | gtex_brain_putamen_basal |
| rs4936121 | 11 | 130733878 | SNX19 | ENSG00000120451.6 | 4.004E-7 | 0 | 52526 | gtex_brain_putamen_basal |
| rs4937580 | 11 | 130734270 | SNX19 | ENSG00000120451.6 | 4.022E-7 | 0 | 52134 | gtex_brain_putamen_basal |
| rs2282579 | 11 | 130735482 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 50922 | gtex_brain_putamen_basal |
| rs4411284 | 11 | 130738568 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 47836 | gtex_brain_putamen_basal |
| rs10791100 | 11 | 130738946 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 47458 | gtex_brain_putamen_basal |
| rs2236711 | 11 | 130739284 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 47120 | gtex_brain_putamen_basal |
| rs2236717 | 11 | 130739887 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 46517 | gtex_brain_putamen_basal |
| rs4937581 | 11 | 130740335 | SNX19 | ENSG00000120451.6 | 4.58E-7 | 0 | 46069 | gtex_brain_putamen_basal |
| rs2155358 | 11 | 130740357 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 46047 | gtex_brain_putamen_basal |
| rs4936123 | 11 | 130740967 | SNX19 | ENSG00000120451.6 | 1.262 e - | 0 | 45437 | gtex_brain_putamen_basal |
| rs4937583 | 11 | 130741606 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 44798 | gtex_brain_putamen_basal |
| rs4937584 | 11 | 130741761 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 44643 | gtex_brain_putamen_basal |
| rs4937585 | 11 | 130741940 | SNX19 | ENSG00000120451.6 | 8.085E-7 | 0 | 44464 | gtex_brain_putamen_basal |
| rs10894273 | 11 | 130742155 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 44249 | gtex_brain_putamen_basal |
| rs1054869 | 11 | 130742630 | SNX19 | ENSG00000120451.6 | 7.402E-7 | 0 | 43774 | gtex_brain_putamen_basal |
| rs10160281 | 11 | 130742788 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 43616 | gtex_brain_putamen_basal |
| rs7125622 | 11 | 130743388 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 43016 | gtex_brain_putamen_basal |
| rs200755497 | 11 | 130743924 | SNX19 | ENSG00000120451.6 | 7.836E-7 | 0 | 42480 | gtex_brain_putamen_basal |
| rs11414920 | 11 | 130743925 | SNX19 | ENSG00000120451.6 | 7.325E-7 | 0 | 42479 | gtex_brain_putamen_basal |
| rs12363140 | 11 | 130744268 | SNX19 | ENSG00000120451.6 | 6.082E-7 | 0 | 42136 | gtex_brain_putamen_basal |
| rs61910787 | 11 | 130744473 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41931 | gtex_brain_putamen_basal |
| rs12361892 | 11 | 130744490 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41914 | gtex_brain_putamen_basal |
| rs12363163 | 11 | 130744509 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41895 | gtex_brain_putamen_basal |
| rs11222369 | 11 | 130744670 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41734 | gtex_brain_putamen_basal |
| rs11222370 | 11 | 130744767 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41637 | gtex_brain_putamen_basal |
| rs10791102 | 11 | 130744977 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41427 | gtex_brain_putamen_basal |
| rs7926167 | 11 | 130745045 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 41359 | gtex_brain_putamen_basal |
| rs7940027 | 11 | 130745591 | SNX19 | ENSG00000120451.6 | 6.158E-7 | 0 | 40813 | gtex_brain_putamen_basal |
| rs1050071 | 11 | 130747231 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 39173 | gtex_brain_putamen_basal |
| rs6590520 | 11 | 130747386 | SNX19 | ENSG00000120451.6 | 7.444E-7 | 0 | 39018 | gtex_brain_putamen_basal |
| rs3190331 | 11 | 130748131 | SNX19 | ENSG00000120451.6 | 4.523E-7 | 0 | 38273 | gtex_brain_putamen_basal |
| rs397799290 | 11 | 130749351 | SNX19 | ENSG00000120451.6 | 1.008E-9 | 0 | 37053 | gtex_brain_putamen_basal |
| rs2155749 | 11 | 130751094 | SNX19 | ENSG00000120451.6 | 1.153E-6 | 0 | 35310 | gtex_brain_putamen_basal |
| rs2155750 | 11 | 130751261 | SNX19 | ENSG00000120451.6 | 1.152E-6 | 0 | 35143 | gtex_brain_putamen_basal |
| rs7942621 | 11 | 130751308 | SNX19 | ENSG00000120451.6 | 1.062E-6 | 0 | 35096 | gtex_brain_putamen_basal |
| rs876641 | 11 | 130752040 | SNX19 | ENSG00000120451.6 | 1.15E-6 | 0 | 34364 | gtex_brain_putamen_basal |
| rs7103988 | 11 | 130754591 | SNX19 | ENSG00000120451.6 | 1.442E-6 | 0 | 31813 | gtex_brain_putamen_basal |
| rs4420278 | 11 | 130754785 | SNX19 | ENSG00000120451.6 | 1.617E-6 | 0 | 31619 | gtex_brain_putamen_basal |
| rs2155751 | 11 | 130755240 | SNX19 | ENSG00000120451.6 | 1.134E-6 | 0 | 31164 | gtex_brain_putamen_basal |
| rs4457753 | 11 | 130755575 | SNX19 | ENSG00000120451.6 | 1.11E-6 | 0 | 30829 | gtex_brain_putamen_basal |
| rs201582106 | 11 | 130755664 | SNX19 | ENSG00000120451.6 | 3.384E-7 | 0 | 30740 | gtex_brain_putamen_basal |
| rs201248703 | 11 | 130755665 | SNX19 | ENSG00000120451.6 | 8.01E-7 | 0 | 30739 | gtex_brain_putamen_basal |
| rs4370948 | 11 | 130755700 | SNX19 | ENSG00000120451.6 | 8.041E-7 | 0 | 30704 | gtex_brain_putamen_basal |
| rs4436551 | 11 | 130755739 | SNX19 | ENSG00000120451.6 | 8.19E-7 | 0 | 30665 | gtex_brain_putamen_basal |
| rs4264159 | 11 | 130755784 | SNX19 | ENSG00000120451.6 | 8.614E-7 | 0 | 30620 | gtex_brain_putamen_basal |
| rs2155752 | 11 | 130755998 | SNX19 | ENSG00000120451.6 | 8.773E-7 | 0 | 30406 | gtex_brain_putamen_basal |
| rs4459316 | 11 | 130756176 | SNX19 | ENSG00000120451.6 | 8.994E-7 | 0 | 30228 | gtex_brain_putamen_basal |
| rs10894275 | 11 | 130756251 | SNX19 | ENSG00000120451.6 | 8.783E-7 | 0 | 30153 | gtex_brain_putamen_basal |
| rs1893017 | 11 | 130756253 | SNX19 | ENSG00000120451.6 | 8.783E-7 | 0 | 30151 | gtex_brain_putamen_basal |
| rs1893018 | 11 | 130756632 | SNX19 | ENSG00000120451.6 | 8.793E-7 | 0 | 29772 | gtex_brain_putamen_basal |
| rs1893019 | 11 | 130756664 | SNX19 | ENSG00000120451.6 | 8.793E-7 | 0 | 29740 | gtex_brain_putamen_basal |
| rs10791103 | 11 | 130757161 | SNX19 | ENSG00000120451.6 | 8.856E-7 | 0 | 29243 | gtex_brain_putamen_basal |
| rs7106973 | 11 | 130758113 | SNX19 | ENSG00000120451.6 | 9.373E-7 | 0 | 28291 | gtex_brain_putamen_basal |
| rs7106995 | 11 | 130758152 | SNX19 | ENSG00000120451.6 | 4.584E-7 | 0 | 28252 | gtex_brain_putamen_basal |
| rs7106684 | 11 | 130758153 | SNX19 | ENSG00000120451.6 | 4.582E-7 | 0 | 28251 | gtex_brain_putamen_basal |
| rs7107595 | 11 | 130758556 | SNX19 | ENSG00000120451.6 | 1E-6 | 0 | 27848 | gtex_brain_putamen_basal |
| rs3751039 | 11 | 130773076 | SNX19 | ENSG00000120451.6 | 4.889E-9 | 0 | 13328 | gtex_brain_putamen_basal |
| rs7107568 | 11 | 130779668 | SNX19 | ENSG00000120451.6 | 4.727E-7 | 0 | 6736 | gtex_brain_putamen_basal |
| rs3751033 | 11 | 130786345 | SNX19 | ENSG00000120451.6 | 1.324E-8 | 0 | 59 | gtex_brain_putamen_basal |
| rs7925214 | 11 | 130794253 | SNX19 | ENSG00000120451.6 | 1.256E-6 | 0 | -7849 | gtex_brain_putamen_basal |
| rs7944782 | 11 | 130795698 | SNX19 | ENSG00000120451.6 | 1.015E-6 | 0 | -9294 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| HOLLMANN APOPTOSIS VIA CD40 UP | 201 | 125 | All SZGR 2.0 genes in this pathway |
| LIU SOX4 TARGETS DN | 309 | 191 | All SZGR 2.0 genes in this pathway |
| OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN | 275 | 168 | All SZGR 2.0 genes in this pathway |
| SENESE HDAC1 TARGETS UP | 457 | 269 | All SZGR 2.0 genes in this pathway |
| LINDGREN BLADDER CANCER CLUSTER 3 DN | 229 | 142 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED MODERATELY VS POORLY UP | 121 | 71 | All SZGR 2.0 genes in this pathway |
| ASTON MAJOR DEPRESSIVE DISORDER DN | 160 | 110 | All SZGR 2.0 genes in this pathway |
| MOREAUX MULTIPLE MYELOMA BY TACI DN | 172 | 107 | All SZGR 2.0 genes in this pathway |
| BAELDE DIABETIC NEPHROPATHY DN | 434 | 302 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 UP | 430 | 288 | All SZGR 2.0 genes in this pathway |