基因页：MCM3
Summary?
| 基因 | 4172 |
| 象征 | MCM3 |
| 同义词 | HCC5|P1-MCM3|P1.h|RLFB |
| 描述 | 微型鲜体维护复杂组件3 |
| 参考 | MIM:602693|HGNC:HGNC:6945|Ensembl：ENSG00000112118|HPRD：04072|Vega：Otthumg0000000014844 |
| Gene type | protein-coding |
| 地图位置 | 6p12 |
| Pascal P值 | 0.194 |
| Sherlock p-value | 0.277 |
| Fetal beta | 0.531 |
| DMG | 2（＃研究） |
| eGene | 尾状基底神经节 皮质 Frontal Cortex BA9 Nucleus accumbens basal ganglia 梭子基底神经节 |
| 支持 | Ascano FMRP目标 |
Gene in Data Sources
| Gene set name | 基因组方法 | 描述 | Info |
|---|---|---|---|
| 简历：PGCNP | 全基因组关联研究 | GWAS | |
| DMG:Montano_2016 | Genome-wide DNA methylation analysis | 该数据集包括CPG与精神分裂症之间的172个复制关联。 | 2 |
| DMG:Nishioka_2013 | Genome-wide DNA methylation analysis | The authors investigated the methylation profiles of DNA in peripheral blood cells from 18 patients with first-episode schizophrenia (FESZ) and from 15 normal controls. | 2 |
| GSMA_IIE | Genome scan meta-analysis (European-ancestry samples) | Psr: 0.04433 | |
| 网络 | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.0069 |
Section I. Genetics and epigenetics annotation
差异甲基化基因
差异甲基化基因| 探测 | Chromosome | Position | 最近的基因 | P (dis) | beta（dis） | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| CG07333545 | 6 | 52170606 | MCM3 | 1.44E-5 | -0.011 | 0.052 | DMG:Montano_2016 |
| CG27638713 | 6 | 52149159 | MCM3 | -0.024 | 0.4 | DMG:Nishioka_2013 |
EQTL注释
| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | PVALUE | qvalue | TSS distance | EQTL类型 |
|---|---|---|---|---|---|---|---|---|
| rs6933615 | 6 | 52264514 | MCM3 | ENSG00000112118.13 | 2.722E-7 | 0 | -114835 | gtex_brain_putamen_basal |
| RS112358192 | 6 | 52277217 | MCM3 | ENSG00000112118.13 | 2.304E-7 | 0 | -127538 | gtex_brain_putamen_basal |
| RS9474218 | 6 | 52277984 | MCM3 | ENSG00000112118.13 | 2.722E-7 | 0 | -128305 | gtex_brain_putamen_basal |
| rs58685840 | 6 | 52285060 | MCM3 | ENSG00000112118.13 | 5.573E-8 | 0 | -135381 | gtex_brain_putamen_basal |
| RS546247 | 6 | 52292881 | MCM3 | ENSG00000112118.13 | 1.515E-8 | 0 | -143202 | gtex_brain_putamen_basal |
| rs67642847 | 6 | 52301785 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -152106 | gtex_brain_putamen_basal |
| RS67736214 | 6 | 52302042 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -152363 | gtex_brain_putamen_basal |
| RS539295 | 6 | 52303048 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -153369 | gtex_brain_putamen_basal |
| rs553329 | 6 | 52306670 | MCM3 | ENSG00000112118.13 | 5.881 e-9 | 0 | -156991 | gtex_brain_putamen_basal |
| rs631603 | 6 | 52314213 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -164534 | gtex_brain_putamen_basal |
| RS642679 | 6 | 52314384 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -164705 | gtex_brain_putamen_basal |
| rs111837113 | 6 | 52315259 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -165580 | gtex_brain_putamen_basal |
| RS59160834 | 6 | 52324249 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -174570 | gtex_brain_putamen_basal |
| RS2104333 | 6 | 52324496 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -174817 | gtex_brain_putamen_basal |
| rs60675996 | 6 | 52324733 | MCM3 | ENSG00000112118.13 | 1.504E-8 | 0 | -175054 | gtex_brain_putamen_basal |
| RS16882561 | 6 | 52329510 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -179831 | gtex_brain_putamen_basal |
| RS66608904 | 6 | 52331777 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -182098 | gtex_brain_putamen_basal |
| RS112649755 | 6 | 52333837 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -184158 | gtex_brain_putamen_basal |
| rs111743208 | 6 | 52336926 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -187247 | gtex_brain_putamen_basal |
| rs616248 | 6 | 52338522 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -188843 | gtex_brain_putamen_basal |
| RS1266787 | 6 | 52343899 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -194220 | gtex_brain_putamen_basal |
| RS515432 | 6 | 52344662 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -194983 | gtex_brain_putamen_basal |
| RS1266789 | 6 | 52346506 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -196827 | gtex_brain_putamen_basal |
| RS55934038 | 6 | 52348455 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -198776 | gtex_brain_putamen_basal |
| rs55953467 | 6 | 52356259 | MCM3 | ENSG00000112118.13 | 1.516E-8 | 0 | -206580 | gtex_brain_putamen_basal |
| RS72925235 | 6 | 52361027 | MCM3 | ENSG00000112118.13 | 1.519E-8 | 0 | -211348 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Devlopment期间的基因表达（BrainCloud）
Footnote:
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26后概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section III. Gene Ontology annotation
| Molecular function | GO term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | - | |
| GO:0003677 | DNA结合 | IEA | - | |
| GO:0003677 | DNA结合 | TAS | 1549468 | |
| GO:0005515 | protein binding | IPI | 12364596|15232106|15654075 |17353931 |
|
| GO:0005524 | ATP结合 | IEA | - | |
| 去：0017111 | 核苷 - 三磷酸酶活性 | IEA | - | |
| 生物过程 | GO term | Evidence | Neuro keywords | PubMed ID |
| 去：0006355 | regulation of transcription, DNA-dependent | IEA | - | |
| 去：0006350 | transcription | IEA | - | |
| 去：0006270 | DNA复制启动 | TAS | 1549468 | |
| 去：0006260 | DNA replication | 经验 | 12791985 | |
| 去：0006260 | DNA replication | IEA | - | |
| 去：0007049 | 细胞周期 | IEA | - | |
| 细胞成分 | GO term | Evidence | Neuro keywords | PubMed ID |
| GO:0005634 | 核 | 艾达 | 18029348 | |
| GO:0005634 | 核 | IEA | - | |
| GO:0005654 | 核质 | 经验 | 10436018|10846177|11095689 |11931757|12045100 |15226314|15707391 |
|
| GO:0005658 | alpha DNA polymerase:primase complex | TAS | 1549468 | |
| GO:0005730 | 核仁 | 艾达 | 18029348 | |
| GO:0005737 | cytoplasm | 艾达 | 18029348 |
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| CCDC5 | FLJ21094 | FLJ40084 | HEI-C | HsT1461 | coiled-coil domain containing 5 (spindle associated) | - | HPRD | 15232106 |
| CDC45L | CDC45 | CDC45L2 | PORC-PI-1 | CDC45 cell division cycle 45-like (S. cerevisiae) | Two-hybrid | BioGRID | 12614612 |
| CDC6 | cdc18l |HSCDC18 |HSCDC6 | cell division cycle 6 homolog (S. cerevisiae) | - | HPRD，Biogrid | 10464337|11046155 |
| CDC7 | cdc7l1 |HSCDC7 |HSK1 |MGC117361 |MGC126237 |MGC126238 |HUCDC7 | cell division cycle 7 homolog (S. cerevisiae) | - | HPRD，Biogrid | 9250678 |
| CDC7 | cdc7l1 |HSCDC7 |HSK1 |MGC117361 |MGC126237 |MGC126238 |HUCDC7 | cell division cycle 7 homolog (S. cerevisiae) | - | HPRD | 9250678|15232106 |
| CDK2 | p33（CDK2） | 依赖细胞周期蛋白的激酶2 | - | HPRD | 15232106 |
| DBF4 | 问|chif |DBF4A |ZDBF1 | DBF4同源物（S. cerevisiae） | - | HPRD，Biogrid | 12614612 |
| ENSA | MGC4319 |MGC78563 |MGC8394 | endosulfine alpha | Affinity Capture-MS | BioGRID | 17353931 |
| MCM10 | CNA43 |DNA43 |MGC126776 |Pro2249 | 微型冰瘤维护复杂组件10 | - | HPRD，Biogrid | 11095689|15232106 |
| MCM2 | BM28 | CCNL1 | CDCL1 | D3S3194 | KIAA0030 | MGC10606 | MITOTIN | cdc19 | 微型鲜体维护复杂组件2 | - | HPRD，Biogrid | 12614612 |
| MCM2 | BM28 | CCNL1 | CDCL1 | D3S3194 | KIAA0030 | MGC10606 | MITOTIN | cdc19 | 微型鲜体维护复杂组件2 | Mcm2 interacts with Mcm3. | BIND | 15236977 |
| MCM2 | BM28 | CCNL1 | CDCL1 | D3S3194 | KIAA0030 | MGC10606 | MITOTIN | cdc19 | 微型鲜体维护复杂组件2 | MCM2与MCM3相互作用。 | BIND | 15236977 |
| MCM3AP | FLJ44336 |FLJ45306 |ganp |KIAA0572 |MAP80 | 微型鲜体维护复杂组件3associated protein | - | HPRD | 9712829|10733502 |11024281|12226073 |
| MCM3AP | FLJ44336 |FLJ45306 |ganp |KIAA0572 |MAP80 | 微型鲜体维护复杂组件3associated protein | Affinity Capture-Western Two-hybrid |
BioGRID | 9712829|10733502 |12226073 |
| MCM5 | cdc46 |MGC5315 |P1-CDC46 | 微型鲜体维护复杂组件5 | - | HPRD，Biogrid | 11248027|12614612 |
| MCM5 | cdc46 |MGC5315 |P1-CDC46 | 微型鲜体维护复杂组件5 | MCM3interacts with MCM5. | BIND | 15236977 |
| MCM5 | cdc46 |MGC5315 |P1-CDC46 | 微型鲜体维护复杂组件5 | Mcm3 interacts with Mcm5. | BIND | 15236977 |
| MCM7 | CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146 | 微型鲜体维护复杂组件7 | MCM3与MCM7相互作用。 | BIND | 15236977 |
| MCM7 | CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146 | 微型鲜体维护复杂组件7 | - | HPRD | 7601140|8631321 |10464337 |
| MCM7 | CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146 | 微型鲜体维护复杂组件7 | Mcm3 interacts with Mcm7. | BIND | 15236977 |
| MCM7 | CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146 | 微型鲜体维护复杂组件7 | Affinity Capture-Western 共同分级 Two-hybrid |
BioGRID | 9099751|10464337 |11779870|12614612 |
| ORC4L | ORC4 |ORC4P | origin recognition complex, subunit 4-like (yeast) | Two-hybrid | BioGRID | 12614612 |
| ORC5L | ORC5 | ORC5P | ORC5T | origin recognition complex, subunit 5-like (yeast) | Two-hybrid | BioGRID | 12614612 |
| PAK2 | PAK65 | PAKgamma | P21蛋白（CDC42/RAC）激活激酶2 | Affinity Capture-MS | BioGRID | 17353931 |
| PNKP | PNK | polynucleotide kinase 3'-phosphatase | Affinity Capture-MS | BioGRID | 17353931 |
| PTP4A3 | PRL-3 | PRL-R | PRL3 | protein tyrosine phosphatase type IVA, member 3 | Affinity Capture-MS | BioGRID | 17353931 |
| RPA2 | repa2 |RPA32 | 复制蛋白A2, 32 kda | Two-hybrid | BioGRID | 12614612 |
| SNCG | BCSG1 |Sr | 突触核蛋白，伽马（乳腺癌特异性蛋白1） | Affinity Capture-MS | BioGRID | 17353931 |
| STAT1 | DKFZp686B04100 | ISGF-3 | STAT91 | signal transducer and activator of transcription 1, 91kDa | - | HPRD | 11248027 |
| WDR8 | FLJ20430 |MGC99569 | WD重复域8 | Affinity Capture-MS | BioGRID | 17353931 |
Section V. Pathway annotation
| Pathway name | Pathway size | ＃SZGR 2.0途径中的基因 | Info |
|---|---|---|---|
| KeGG DNA复制 | 36 | 21 | All SZGR 2.0 genes in this pathway |
| KEGG CELL CYCLE | 128 | 84 | All SZGR 2.0 genes in this pathway |
| Biocarta MCM途径 | 18 | 8 | All SZGR 2.0 genes in this pathway |
| PID E2F途径 | 74 | 48 | All SZGR 2.0 genes in this pathway |
| REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | 31 | 16 | All SZGR 2.0 genes in this pathway |
| REACTOME CELL CYCLE | 421 | 253 | All SZGR 2.0 genes in this pathway |
| REACTOME ORC1 REMOVAL FROM CHROMATIN | 67 | 37 | All SZGR 2.0 genes in this pathway |
| Reactome细胞周期有丝分裂 | 325 | 185 | All SZGR 2.0 genes in this pathway |
| Reactome细胞周期检查点 | 124 | 70 | All SZGR 2.0 genes in this pathway |
| REACTOME M G1 TRANSITION | 81 | 45 | All SZGR 2.0 genes in this pathway |
| Reactome G1 S过渡 | 112 | 63 | All SZGR 2.0 genes in this pathway |
| REACTOME SYNTHESIS OF DNA | 92 | 53 | All SZGR 2.0 genes in this pathway |
| REACTOME MITOTIC G1 G1 S PHASES | 137 | 79 | All SZGR 2.0 genes in this pathway |
| REACTOME MITOTIC M M G1 PHASES | 172 | 98 | All SZGR 2.0 genes in this pathway |
| REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX | 65 | 36 | All SZGR 2.0 genes in this pathway |
| REACTOME DNA REPLICATION | 192 | 110 | All SZGR 2.0 genes in this pathway |
| REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | 38 | 18 | All SZGR 2.0 genes in this pathway |
| Reactome放松DNA | 11 | 6 | All SZGR 2.0 genes in this pathway |
| Reactome G2 M检查点 | 45 | 23 | All SZGR 2.0 genes in this pathway |
| Reactome s阶段 | 109 | 66 | All SZGR 2.0 genes in this pathway |
| 反应组DNA链伸长 | 30 | 18 | All SZGR 2.0 genes in this pathway |
| PYEON HPV阳性肿瘤向上 | 98 | 47 | All SZGR 2.0 genes in this pathway |
| SOTIRIOU BREAST CANCER GRADE 1 VS 3 UP | 151 | 84 | All SZGR 2.0 genes in this pathway |
| Puiffe入侵被腹水抑制 | 82 | 51 | All SZGR 2.0 genes in this pathway |
| casorelli急性寄生虫细胞白血病DN | 663 | 425 | All SZGR 2.0 genes in this pathway |
| DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP | 1382 | 904 | All SZGR 2.0 genes in this pathway |
| BASAKI YBX1 TARGETS UP | 290 | 177 | All SZGR 2.0 genes in this pathway |
| GINESTIER BREAST CANCER 20Q13 AMPLIFICATION DN | 180 | 101 | All SZGR 2.0 genes in this pathway |
| Tien肠益生菌24小时 | 557 | 331 | All SZGR 2.0 genes in this pathway |
| EWSR1 FLII融合的Kinsey靶标 | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| DODD鼻咽癌DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| PROVENZANI METASTASIS UP | 194 | 112 | All SZGR 2.0 genes in this pathway |
| ENK UV RESPONSE KERATINOCYTE UP | 530 | 342 | All SZGR 2.0 genes in this pathway |
| Markey RB1急性LOF DN | 228 | 137 | All SZGR 2.0 genes in this pathway |
| berenjeno由rhoa up转变 | 536 | 340 | All SZGR 2.0 genes in this pathway |
| JOHANSSON GLIOMAGENESIS BY PDGFB UP | 58 | 44 | All SZGR 2.0 genes in this pathway |
| MARKS HDAC TARGETS UP | 23 | 15 | All SZGR 2.0 genes in this pathway |
| Kong E2F3目标 | 97 | 58 | All SZGR 2.0 genes in this pathway |
| Eguchi细胞周期RB1目标 | 23 | 13 | All SZGR 2.0 genes in this pathway |
| RIZ ERYTHROID DIFFERENTIATION | 77 | 51 | All SZGR 2.0 genes in this pathway |
| LI LUNG CANCER | 41 | 30 | All SZGR 2.0 genes in this pathway |
| PATIL LIVER CANCER | 747 | 453 | All SZGR 2.0 genes in this pathway |
| MOHANKUMAR TLX1 TARGETS UP | 414 | 287 | All SZGR 2.0 genes in this pathway |
| GRUETZMANN PANCREATIC CANCER UP | 358 | 245 | All SZGR 2.0 genes in this pathway |
| LIANG HEMATOPOIESIS STEM CELL NUMBER SMALL VS HUGE DN | 33 | 22 | All SZGR 2.0 genes in this pathway |
| PUJANA BREAST CANCER LIT INT NETWORK | 101 | 73 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA2 PCC NETWORK | 423 | 265 | All SZGR 2.0 genes in this pathway |
| PUJANA CHEK2 PCC NETWORK | 779 | 480 | All SZGR 2.0 genes in this pathway |
| 考夫曼黑色素瘤复发 | 61 | 25 | All SZGR 2.0 genes in this pathway |
| BUYTAERT PHOTODYNAMIC THERAPY STRESS DN | 637 | 377 | All SZGR 2.0 genes in this pathway |
| 洛佩兹MBD目标 | 957 | 597 | All SZGR 2.0 genes in this pathway |
| CAFFAREL RESPONSE TO THC DN | 31 | 23 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP | 236 | 139 | All SZGR 2.0 genes in this pathway |
| RICKMAN TUMOR DIFFERENTIATED MODERATELY VS POORLY DN | 15 | 8 | All SZGR 2.0 genes in this pathway |
| Gotzmann上皮到间充质转变 | 69 | 55 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES 1 | 379 | 235 | All SZGR 2.0 genes in this pathway |
| Benporath Myc Max目标 | 775 | 494 | All SZGR 2.0 genes in this pathway |
| BENPORATH PROLIFERATION | 147 | 80 | All SZGR 2.0 genes in this pathway |
| GEORGES CELL CYCLE MIR192 TARGETS | 62 | 46 | All SZGR 2.0 genes in this pathway |
| GEORGES TARGETS OF MIR192 AND MIR215 | 893 | 528 | All SZGR 2.0 genes in this pathway |
| SUNG METASTASIS STROMA DN | 54 | 34 | All SZGR 2.0 genes in this pathway |
| Mori大型BII淋巴细胞向上 | 86 | 49 | All SZGR 2.0 genes in this pathway |
| MORI IMMATURE B LYMPHOCYTE DN | 90 | 55 | All SZGR 2.0 genes in this pathway |
| KAUFFMANN DNA REPLICATION GENES | 147 | 87 | All SZGR 2.0 genes in this pathway |
| GOLUB ALL VS AML UP | 24 | 20 | All SZGR 2.0 genes in this pathway |
| SHEPARD BMYB MORPHOLINO DN | 200 | 112 | All SZGR 2.0 genes in this pathway |
| MANALO缺氧DN | 289 | 166 | All SZGR 2.0 genes in this pathway |
| TARTE PLASMA CELL VS PLASMABLAST DN | 309 | 206 | All SZGR 2.0 genes in this pathway |
| 由E2F绑定的REN | 61 | 40 | All SZGR 2.0 genes in this pathway |
| PEART HDAC增殖集群DN | 76 | 57 | All SZGR 2.0 genes in this pathway |
| Sasaki成人T细胞白血病 | 176 | 122 | All SZGR 2.0 genes in this pathway |
| SANSOM APC TARGETS UP | 126 | 84 | All SZGR 2.0 genes in this pathway |
| MATSUDA NATURAL KILLER DIFFERENTIATION | 475 | 313 | All SZGR 2.0 genes in this pathway |
| Hoxa9和Meis1的赫斯目标 | 65 | 44 | All SZGR 2.0 genes in this pathway |
| YAGI AML FAB MARKERS | 191 | 131 | All SZGR 2.0 genes in this pathway |
| iglesias e2f目标 | 151 | 103 | All SZGR 2.0 genes in this pathway |
| Kamminga Ezh2目标 | 41 | 26 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS EARLY PROGENITOR | 532 | 309 | All SZGR 2.0 genes in this pathway |
| Kaab失败的心脏中庭DN | 141 | 99 | All SZGR 2.0 genes in this pathway |
| RHODES CANCER META SIGNATURE | 64 | 47 | All SZGR 2.0 genes in this pathway |
| RHODES UNDIFFERENTIATED CANCER | 69 | 44 | All SZGR 2.0 genes in this pathway |
| BURTON ADIPOGENESIS 3 | 101 | 64 | All SZGR 2.0 genes in this pathway |
| 布朗HCMV感染18小时 | 178 | 111 | All SZGR 2.0 genes in this pathway |
| IE86 CMV蛋白的歌曲目标 | 60 | 42 | All SZGR 2.0 genes in this pathway |
| CUI TCF21 TARGETS 2 UP | 428 | 266 | All SZGR 2.0 genes in this pathway |
| MARTINEZ RESPONSE TO TRABECTEDIN DN | 271 | 175 | All SZGR 2.0 genes in this pathway |
| BURTON ADIPOGENESIS PEAK AT 16HR | 40 | 24 | All SZGR 2.0 genes in this pathway |
| CREIGHTON ENDOCRINE THERAPY RESISTANCE 1 | 528 | 324 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
| MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |
| SARRIO EPITHELIAL MESENCHYMAL TRANSITION UP | 180 | 114 | All SZGR 2.0 genes in this pathway |
| Fujii YBX1靶向DN | 202 | 132 | All SZGR 2.0 genes in this pathway |
| 阿塞维多肝癌 | 973 | 570 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE UP | 863 | 514 | All SZGR 2.0 genes in this pathway |
| Mir34b和Mir34C的丰田目标 | 463 | 262 | All SZGR 2.0 genes in this pathway |
| ZHENG GLIOBLASTOMA PLASTICITY UP | 250 | 168 | All SZGR 2.0 genes in this pathway |
| GRADE COLON CANCER UP | 871 | 505 | All SZGR 2.0 genes in this pathway |
| GRADE COLON AND RECTAL CANCER UP | 285 | 167 | All SZGR 2.0 genes in this pathway |
| BLUM RESPONSE TO SALIRASIB DN | 342 | 220 | All SZGR 2.0 genes in this pathway |
| MUELLER PLURINET | 299 | 189 | All SZGR 2.0 genes in this pathway |
| Boylan多发性骨髓瘤C | 47 | 29 | All SZGR 2.0 genes in this pathway |
| Frasor对Serm或Fulvestrant DN的响应 | 50 | 29 | All SZGR 2.0 genes in this pathway |
| Goldrath抗原反应 | 346 | 192 | All SZGR 2.0 genes in this pathway |
| Ruiz TNC靶向DN | 142 | 79 | All SZGR 2.0 genes in this pathway |
| Chang Core血清反应 | 212 | 128 | All SZGR 2.0 genes in this pathway |
| ZHANG TLX TARGETS 60HR DN | 277 | 166 | All SZGR 2.0 genes in this pathway |
| 陈代谢综合征网络 | 1210 | 725 | All SZGR 2.0 genes in this pathway |
| CROONQUIST IL6 DEPRIVATION DN | 98 | 69 | All SZGR 2.0 genes in this pathway |
| Croonquist NRAS信号传导DN | 72 | 47 | All SZGR 2.0 genes in this pathway |
| CROONQUIST NRAS VS STROMAL STIMULATION DN | 99 | 65 | All SZGR 2.0 genes in this pathway |
| Ishida E2F目标 | 53 | 27 | All SZGR 2.0 genes in this pathway |
| BOYAULT LIVER CANCER SUBCLASS G23 UP | 52 | 35 | All SZGR 2.0 genes in this pathway |
| KOBAYASHI EGFR SIGNALING 24HR DN | 251 | 151 | All SZGR 2.0 genes in this pathway |
| Fournier Acinar Development 2 | 277 | 172 | All SZGR 2.0 genes in this pathway |
| PYEON CANCER HEAD AND NECK VS CERVICAL UP | 193 | 95 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA UP | 207 | 143 | All SZGR 2.0 genes in this pathway |
| CAIRO HEPATOBLASTOMA CLASSES UP | 605 | 377 | All SZGR 2.0 genes in this pathway |
| DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
| 黄胚胎干细胞核心 | 335 | 193 | All SZGR 2.0 genes in this pathway |
| YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 12 | 79 | 54 | All SZGR 2.0 genes in this pathway |
| WU APOPTOSIS BY CDKN1A VIA TP53 | 55 | 31 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE DN | 841 | 431 | All SZGR 2.0 genes in this pathway |
| 别致的AS RB1 TARGETS SENESCENT | 572 | 352 | All SZGR 2.0 genes in this pathway |
| Chicas RB1靶向低血清 | 100 | 51 | All SZGR 2.0 genes in this pathway |
| 别致的AS RB1 TARGETS GROWING | 243 | 155 | All SZGR 2.0 genes in this pathway |
| Wang对GSK3抑制剂SB216763 DN的响应 | 374 | 217 | All SZGR 2.0 genes in this pathway |
| Dutertre雌二醇反应6小时 | 229 | 149 | All SZGR 2.0 genes in this pathway |
| Dutertre雌二醇反应24小时 | 324 | 193 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 2 DN | 336 | 211 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE LATE | 1137 | 655 | All SZGR 2.0 genes in this pathway |
| LEE BMP2 TARGETS DN | 882 | 538 | All SZGR 2.0 genes in this pathway |
| FEVR CTNNB1 TARGETS DN | 553 | 343 | All SZGR 2.0 genes in this pathway |
| Gobert少突胶质细胞差异化 | 570 | 339 | All SZGR 2.0 genes in this pathway |
| 前列腺癌模型中的Acevedo FGFR1靶标 | 289 | 184 | All SZGR 2.0 genes in this pathway |
| ZHOU CELL CYCLE GENES IN IR RESPONSE 6HR | 85 | 49 | All SZGR 2.0 genes in this pathway |
| ZHOU CELL CYCLE GENES IN IR RESPONSE 24HR | 128 | 73 | All SZGR 2.0 genes in this pathway |