SZGR2 - Beplay体育中心

Summary？

GeneID	4176
Symbol	MCM7
Synonyms	cdc47 \| mcm2 \| P1.1-MCM3 \| P1CDC47 \| P85MCM \| PNAS146 \| PPP1R104
描述	minichromosome maintenance complex component 7
Reference	MIM：600592\|HGNC:HGNC:6950\|Ensembl:ENSG00000166508\|HPRD:01154\|Vega:OTTHUMG00000154671
基因类型	蛋白质编码
Map location	7Q21.3-Q22.1
Pascal p-value	0.461
Sherlock p-value	8.163E-4
胎儿β	2.271
DMG	2(# studies)
Support	Ascano FMRP targets

Gene in Data Sources

基因集名称	Method of gene set	描述	信息
DMG：Nishioka_2013	全基因组DNA甲基化分析	作者研究了来自18例第一期精神分裂症（FESZ）和15个正常对照的18例外周血细胞中DNA的甲基化谱。	2
DMG:vanEijk_2014	全基因组DNA甲基化分析	This dataset includes 432 differentially methylated CpG sites corresponding to 391 unique transcripts between schizophrenia patients (n=260) and unaffected controls (n=250).	2
PMID：cooccur	High-throughput literature-search	PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	点击显示详细信息
Network	Shortest path distance of core genes in the Human protein-protein interaction network	PPI网络中最短路径的贡献：0.013

Section I. Genetics and epigenetics annotation

Differentially methylated gene

Probe	染色体	位置	Nearest gene	p（dis）	β(dis)	fdr（dis）	学习
cg26023204	7	99699378	MCM7		-0.02	0.87	DMG：Nishioka_2013
cg13650156	7	99970502	MCM7	2.22E-6	3.895		DMG:vanEijk_2014

第二节。转录组注释

一般基因表达（GTEX）

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
cnpy2	0.86	0.81
COPS6	0.86	0.84
CCDC56	0.86	0.86
myl6	0.86	0.83
CHMP2A	0.86	0.83
PSMA5	0.85	0.83
NHP2	0.85	0.82
SPAG7	0.85	0.85
TOMM5	0.85	0.84
TSTA3	0.84	0.81

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
AF347015.26	-0.62	-0.56
AF347015.8	-0.59	-0.51
AF347015.2	-0.58	-0.51
AF347015.15	-0.58	-0.53
AF347015.18	-0.58	-0.51
mt-cyb	-0.56	-0.52
MT-CO2	-0.56	-0.47
AF347015.33	-0.56	-0.50
AF347015.27	-0.55	-0.52
MT-ATP8	-0.55	-0.52

第三节。基因本体论注释

Molecular function	去学期	证据	神经关键字	PubMed ID
去：0000166	nucleotide binding	IEA		-
去：0003677	DNA binding	TAS		15538388
去：0005515	蛋白质结合	IPI		10518787\|15538388\|16438930
去：0005524	ATP binding	IEA		-
GO:0017111	nucleoside-triphosphatase activity	IEA		-
Biological process	去学期	证据	神经关键字	PubMed ID
GO:0006355	调节转录，DNA依赖性的调节	IEA		-
GO:0006350	转录	IEA		-
GO:0006270	基因复制initiation	IEA		-
GO:0006260	基因复制	EXP		12791985
GO:0006260	基因复制	TAS		8798650
GO:0007049	cell cycle	IEA		-
去：0006974	对DNA损伤刺激的反应	IMP		15538388
GO：0042325	调节磷酸化	IMP		15538388
Cellular component	去学期	证据	神经关键字	PubMed ID
GO:0000785	chromatin	TAS		8798650
去：0005634	nucleus	IEA		-
去：0005654	nucleoplasm	EXP		10436018\|10846177\|11095689 \|11931757\|12045100 \|15226314\|15707391
去：0005737	cytoplasm	IDA		18029348
GO：0042555	MCM complex	IMP		15538388

Section IV. Protein-protein interaction annotation

Interactors	别名b	官方全名b	实验	Source	PubMed ID
ATR	frp1 \|mec1 \|sckl \|SCKL1	ataxia telangiectasia and Rad3 related	亲和力捕获 - 韦斯特恩	Biogrid	15210935
一次旅行	DKFZp762J2115 \| FLJ12343 \| MGC20625 \| MGC21482 \| MGC26740	ATR interacting protein	亲和力捕获 - 韦斯特恩	Biogrid	15210935
CCNH	cak \|p34 \|p37	细胞周期蛋白h	-	HPRD,BioGRID	11056214
CDC45L	CDC45 \| CDC45L2 \| PORC-PI-1	CDC45细胞分裂周期45样（酿酒酵母）	-	HPRD,BioGRID	10518787\|12614612
CDC6	CDC18L \| HsCDC18 \| HsCDC6	细胞分裂周期6同源物（S. cerevisiae）	-	HPRD,BioGRID	10464337\|12614612
CDC7	CDC7L1 \| HsCDC7 \| Hsk1 \| MGC117361 \| MGC126237 \| MGC126238 \| huCDC7	细胞红利ion cycle 7 homolog (S. cerevisiae)	-	HPRD,BioGRID	12614612
CDK7	cak1 \|CDKN7 \|mo15 \|STK1 \|P39MO15	cyclin-dependent kinase 7	-	HPRD,BioGRID	11056214
CNOT8	CAF1 \|加利福尼亚\|pop2 \|HCAF1	CCR4-NOT transcription complex, subunit 8	Affinity Capture-MS	Biogrid	17353931
CRLS1	C20orf155 C \|LS1 \| GCD10 \| dJ967N21.6	cardiolipin synthase 1	-	HPRD	12771218
DBF4	ASK \| CHIF \| DBF4A \| ZDBF1	DBF4 homolog (S. cerevisiae)	-	HPRD,BioGRID	12614612
FHL2	AAG11 \|Dral \|Slim3	four and a half LIM domains 2	-	HPRD,BioGRID	10649446
GIPC1	C19orf3 \| GIPC \| GLUT1CBP \| Hs.6454 \| IIP-1 \| MGC15889 \| MGC3774 \| NIP \| RGS19IP1 \| SEMCAP \| SYNECTIIN \| SYNECTIN \| TIP-2	GIPC PDZ domain containing family, member 1	Affinity Capture-MS	Biogrid	17353931
GSTK1	GST13	谷胱甘肽S-转移酶Kappa 1	Affinity Capture-MS	Biogrid	17353931
HIST3H3	H3.4 \| H3/g \| H3FT \| H3t \| MGC126886 \| MGC126888	histone cluster 3, H3	-	HPRD,BioGRID	8798650
ikbkg	AMCBX1 \| FIP-3 \| FIP3 \| Fip3p \| IKK-gamma \| IP \| IP1 \| IP2 \| IPD2 \| NEMO	B细胞，激酶γ中Kappa光多肽基因增强子的抑制剂	-	HPRD	14743216
mbip	-	MAP3K12 binding inhibitory protein 1	Two-hybrid	Biogrid	16189514
MCM10	CNA43 \| DNA43 \| MGC126776 \| PRO2249	minichromosome maintenance complex component 10	-	HPRD,BioGRID	11095689\|15232106
MCM2	BM28 \| CCNL1 \| CDCL1 \| D3S3194 \| KIAA0030 \| MGC10606 \| MITOTIN \| cdc19	minichromosome maintenance complex component 2	亲和力捕获 - 韦斯特恩 Co-purification in vivo 重构的复合物 Two-hybrid	Biogrid	8798650\|9099751 \|10567526\|10748114 \|12207017\|12614612 \|12694531
MCM2	BM28 \| CCNL1 \| CDCL1 \| D3S3194 \| KIAA0030 \| MGC10606 \| MITOTIN \| cdc19	minichromosome maintenance complex component 2	-	HPRD	8798650\|10567526 \|10748114\|12207017
MCM2	BM28 \| CCNL1 \| CDCL1 \| D3S3194 \| KIAA0030 \| MGC10606 \| MITOTIN \| cdc19	minichromosome maintenance complex component 2	-	HPRD	8798650\|10567526 \|10748114\|12207017\|15232106
MCM3	HCC5 \|MGC1157 \|P1-MCM3 \|p1.h \|RLFB	minichromosome maintenance complex component 3	MCM3 interacts with MCM7.	绑定	15236977
MCM3	HCC5 \|MGC1157 \|P1-MCM3 \|p1.h \|RLFB	minichromosome maintenance complex component 3	-	HPRD	7601140\|8631321 \|10464337
MCM3	HCC5 \|MGC1157 \|P1-MCM3 \|p1.h \|RLFB	minichromosome maintenance complex component 3	MCM3与MCM7相互作用。	绑定	15236977
MCM3	HCC5 \|MGC1157 \|P1-MCM3 \|p1.h \|RLFB	minichromosome maintenance complex component 3	亲和力捕获 - 韦斯特恩 Co-fractionation Two-hybrid	Biogrid	9099751\|10464337 \|11779870\|12614612
MCM4	cdc21 \|cdc54 \|MGC33310 \|P1-CDC21 \|HCDC21	minichromosome maintenance complex component 4	亲和力捕获 - 韦斯特恩 in vivo 重构的复合物	Biogrid	8798650\|9099751 \|10748114\|12207017 \|12694531
MCM4	cdc21 \|cdc54 \|MGC33310 \|P1-CDC21 \|HCDC21	minichromosome maintenance complex component 4	Mcm4 interacts with Mcm7.	绑定	15236977
MCM4	cdc21 \|cdc54 \|MGC33310 \|P1-CDC21 \|HCDC21	minichromosome maintenance complex component 4	-	HPRD	7601140\|8631321 \|8798650\|10567526 \|10748114\|12207017
MCM4	cdc21 \|cdc54 \|MGC33310 \|P1-CDC21 \|HCDC21	minichromosome maintenance complex component 4	MCM4与MCM7相互作用。	绑定	15236977
MCM5	CDC46 \| MGC5315 \| P1-CDC46	minichromosome maintenance complex component 5	亲和力捕获 - 韦斯特恩 Two-hybrid	Biogrid	9099751\|11248027 \|12614612
MCM5	CDC46 \| MGC5315 \| P1-CDC46	minichromosome maintenance complex component 5	-	HPRD	9099751\|12614612
MCM6	MCG40308 \|MIS5 \|P105MCM	minichromosome maintenance complex component 6	-	HPRD	8798650\|10567526 \|10748114\|12207017
MCM6	MCG40308 \|MIS5 \|P105MCM	minichromosome maintenance complex component 6	亲和力捕获 - 韦斯特恩 in vivo 重构的复合物 Two-hybrid	Biogrid	8798650\|9099751 \|10748114\|12207017 \|12614612\|12694531
MCM6	MCG40308 \|MIS5 \|P105MCM	minichromosome maintenance complex component 6	-	HPRD	8798650\|10567526 \|10748114\|12207017\|12694531
MCM7	CDABP0042 \| CDC47 \| MCM2 \| P1.1-MCM3 \| P1CDC47 \| P85MCM \| PNAS-146	minichromosome maintenance complex component 7	Mcm7 interacts with itself.	绑定	15236977
MCM7	CDABP0042 \| CDC47 \| MCM2 \| P1.1-MCM3 \| P1CDC47 \| P85MCM \| PNAS-146	minichromosome maintenance complex component 7	重构的复合物 Two-hybrid	Biogrid	12614612\|12694531
MCM8	C20ORF154 \|MGC119522 \|MGC119523 \|MGC12866 \|MGC4816 \|rec \|DJ967N21.5	minichromosome maintenance complex component 8	-	HPRD,BioGRID	12771218
MNAT1	Mat1 \|RNF66 \|TFB3	Menage A Trois同源物1，细胞周期蛋白H装配因子（Xenopus laevis）	-	HPRD,BioGRID	11056214
我的C	Bhlhe39 \|c-myc	V-myc骨髓质体病毒性癌基因同源物（禽类）	Affinity Capture-MS	Biogrid	17353931
NEK6	SID6-1512	NIMA (never in mitosis gene a)-related kinase 6	Affinity Capture-MS	Biogrid	17353931
NFKBIA	IKBA \| MAD-3 \| NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	-	HPRD	14743216
ORC1L	HSORC1 \| ORC1 \| PARC1	origin recognition complex, subunit 1-like (yeast)	-	HPRD,BioGRID	12614612
ORC2L	ORC2	起源识别综合体，亚基2样（酵母）	-	HPRD,BioGRID	12614612
ORC3L	拉特\|Latheo \|ORC3	起源识别综合体，亚基3式（酵母）	-	HPRD,BioGRID	12614612
ORC5L	ORC5 \|ORC5P \|ORC5T	origin recognition complex, subunit 5-like (yeast)	-	HPRD,BioGRID	12614612
PELO	CGI-17 \| PRO1770	pelota homolog (Drosophila)	Affinity Capture-MS	Biogrid	17353931
RB1	OSRC \|RB \|P105-RB \|PRB \|PP110	retinoblastoma 1	-	HPRD,BioGRID	9566894
RB1	OSRC \|RB \|P105-RB \|PRB \|PP110	retinoblastoma 1	MCM7与RB相互作用。	绑定	9566894
RBL1	CP107 \| MGC40006 \| PRB1 \| p107	视网膜母细胞瘤状1（p107）	-	HPRD,BioGRID	9566894
RBL1	CP107 \| MGC40006 \| PRB1 \| p107	视网膜母细胞瘤状1（p107）	MCM7interacts with p107.	绑定	9566894
RBL2	FLJ26459 \| P130 \| Rb2	视网膜母细胞瘤样2（P130）	-	HPRD,BioGRID	9566894
RBL2	FLJ26459 \| P130 \| Rb2	视网膜母细胞瘤样2（P130）	MCM7interacts with p130.	绑定	9566894
RBM8A	BOV-1A \| BOV-1B \| BOV-1C \| MDS014 \| RBM8 \| RBM8B \| Y14 \| ZNRP \| ZRNP1	RNA binding motif protein 8A	Two-hybrid	Biogrid	16189514
RPA1	HSSB \|repa1 \|RF-A \|RP-A \|RPA70	复制蛋白A1，70KDA	-	HPRD,BioGRID	12614612
Th1L	HSPC130 \|Nelf-C \|Nelf-D \|Th1	Th1-like (Drosophila)	Affinity Capture-MS	Biogrid	17353931
TRAF6	MGC:3310 \| RNF85	TNF receptor-associated factor 6	Affinity Capture-MS	Biogrid	17353931
TREX1	AGS1 \| AGS5 \| CRV \| DKFZp434J0310 \| DRN3 \| HERNS	three prime repair exonuclease 1	-	HPRD	15210935
UBE3A	ancr \|AS \|e6-ap \|epve6ap \|FLJ26981 \|HPVE6A	ubiquitin protein ligase E3A	-	HPRD,BioGRID	9852095

Section V. Pathway annotation

路径名	路径大小	# SZGR 2.0 genes in pathway	信息
KEGG DNA REPLICATION	36	21	All SZGR 2.0 genes in this pathway
kegg细胞周期	128	84	All SZGR 2.0 genes in this pathway
BIOCARTA MCM PATHWAY	18	8	All SZGR 2.0 genes in this pathway
PID ATR途径	39	25	All SZGR 2.0 genes in this pathway
复制前复合物的反应组激活	31	16	All SZGR 2.0 genes in this pathway
反应组细胞周期	421	253	All SZGR 2.0 genes in this pathway
Reactome ORC1从染色质中去除	67	37	All SZGR 2.0 genes in this pathway
反应组细胞周期MITOTIC	325	185	All SZGR 2.0 genes in this pathway
反应组细胞周期CHECKPOINTS	124	70	All SZGR 2.0 genes in this pathway
Reactome M G1过渡	81	45	All SZGR 2.0 genes in this pathway
REACTOME G1 S TRANSITION	112	63	All SZGR 2.0 genes in this pathway
REACTOME SYNTHESIS OF DNA	92	53	All SZGR 2.0 genes in this pathway
Reactome有丝分裂G1 G1 S相	137	79	All SZGR 2.0 genes in this pathway
Reactome有丝分裂M M G1相	172	98	All SZGR 2.0 genes in this pathway
复制前复合物的反应组装	65	36	All SZGR 2.0 genes in this pathway
Reactome DNA复制	192	110	All SZGR 2.0 genes in this pathway
ATR的反应组激活复制应力	38	18	All SZGR 2.0 genes in this pathway
REACTOME UNWINDING OF DNA	11	6	All SZGR 2.0 genes in this pathway
REACTOME G2 M CHECKPOINTS	45	23	All SZGR 2.0 genes in this pathway
REACTOME S PHASE	109	66	All SZGR 2.0 genes in this pathway
REACTOME DNA STRAND ELONGATION	30	18	All SZGR 2.0 genes in this pathway
CASORELLI ACUTE PROMYELOCYTIC LEUKEMIA DN	663	425	All SZGR 2.0 genes in this pathway
deurig t细胞促进性白血病	368	234	All SZGR 2.0 genes in this pathway
HORIUCHI WTAP TARGETS DN	310	188	All SZGR 2.0 genes in this pathway
Basaki YBX1靶向	290	177	All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY UP	430	232	All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP	557	331	All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP	1278	748	All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN	1375	806	All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP	633	376	All SZGR 2.0 genes in this pathway
甲状腺癌的甲状腺癌间变性	722	443	All SZGR 2.0 genes in this pathway
MARKEY RB1 CHRONIC LOF UP	115	78	All SZGR 2.0 genes in this pathway
MARKEY RB1 ACUTE LOF DN	228	137	All SZGR 2.0 genes in this pathway
BERENJENO TRANSFORMED BY RHOA UP	536	340	All SZGR 2.0 genes in this pathway
王食道癌与正常	121	72	All SZGR 2.0 genes in this pathway
KAN RESPONSE TO ARSENIC TRIOXIDE	123	80	All SZGR 2.0 genes in this pathway
EGUCHI CELL CYCLE RB1 TARGETS	23	13	All SZGR 2.0 genes in this pathway
riz红细胞分化	77	51	All SZGR 2.0 genes in this pathway
riz红细胞分化HBZ	41	27	All SZGR 2.0 genes in this pathway
牛津拉拉或拉尔布靶向	48	23	All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC网络	1652	1023	All SZGR 2.0 genes in this pathway
Pujana BRCA2 PCC网络	423	265	All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC网络	779	480	All SZGR 2.0 genes in this pathway
KAUFFMANN MELANOMA RELAPSE UP	61	25	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN	1024	594	All SZGR 2.0 genes in this pathway
LOCKWOOD AMPLIFIED IN LUNG CANCER	214	139	All SZGR 2.0 genes in this pathway
TP53和TP73 DN的SCIAN细胞周期目标	22	14	All SZGR 2.0 genes in this pathway
Benporath ES 1	379	235	All SZGR 2.0 genes in this pathway
Benporath MYC带Ebox的目标	230	156	All SZGR 2.0 genes in this pathway
MORI PRE BI LYMPHOCYTE UP	80	54	All SZGR 2.0 genes in this pathway
MORI LARGE PRE BII LYMPHOCYTE UP	86	49	All SZGR 2.0 genes in this pathway
Mori未成熟B淋巴细胞DN	90	55	All SZGR 2.0 genes in this pathway
MORI EMU MYC LYMPHOMA BY ONSET TIME UP	110	69	All SZGR 2.0 genes in this pathway
KAUFFMANN DNA REPLICATION GENES	147	87	All SZGR 2.0 genes in this pathway
LEE LIVER CANCER CIPROFIBRATE DN	66	43	All SZGR 2.0 genes in this pathway
阿斯顿主要抑郁症DN	160	110	All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS UP	108	75	All SZGR 2.0 genes in this pathway
费尔南德斯（Fernandez）由迈克（Myc）约束	182	116	All SZGR 2.0 genes in this pathway
FLECHNER PBL KIDNEY TRANSPLANT REJECTED VS OK DN	51	35	All SZGR 2.0 genes in this pathway
SHIPP DLBCL VS FOLLICULAR LYMPHOMA UP	45	30	All SZGR 2.0 genes in this pathway
PEART HDAC PROLIFERATION CLUSTER DN	76	57	All SZGR 2.0 genes in this pathway
Sansom APC目标	126	84	All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION	475	313	All SZGR 2.0 genes in this pathway
LEI MYB TARGETS	318	215	All SZGR 2.0 genes in this pathway
Affar YY1靶向DN	234	137	All SZGR 2.0 genes in this pathway
VERNELL RETINOBLASTOMA PATHWAY UP	70	47	All SZGR 2.0 genes in this pathway
HESS TARGETS OF HOXA9 AND MEIS1 UP	65	44	All SZGR 2.0 genes in this pathway
IGLESIAS E2F TARGETS UP	151	103	All SZGR 2.0 genes in this pathway
HEDENFALK BREAST CANCER HEREDITARY VS SPORADIC	50	32	All SZGR 2.0 genes in this pathway
WANG CISPLATIN RESPONSE AND XPC DN	228	146	All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病	1691	1088	All SZGR 2.0 genes in this pathway
伯顿成生成3	101	64	All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO CANTHARIDIN DN	69	46	All SZGR 2.0 genes in this pathway
ZHOU TNF SIGNALING 30MIN	54	36	All SZGR 2.0 genes in this pathway
SONG TARGETS OF IE86 CMV PROTEIN	60	42	All SZGR 2.0 genes in this pathway
CUI TCF21目标2向上	428	266	All SZGR 2.0 genes in this pathway
Hedenfalk乳腺癌BRCA1与BRCA2	163	113	All SZGR 2.0 genes in this pathway
Browne HCMV感染24小时	148	96	All SZGR 2.0 genes in this pathway
BURTON ADIPOGENESIS PEAK AT 16HR	40	24	All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 1	528	324	All SZGR 2.0 genes in this pathway
GAVIN IL2 RESPONSIVE FOXP3 TARGETS UP	19	12	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED	1229	713	All SZGR 2.0 genes in this pathway
由E2F4绑定的Marson未刺激	728	415	All SZGR 2.0 genes in this pathway
Sansom APC MYC目标	217	138	All SZGR 2.0 genes in this pathway
Sansom APC目标需要MYC	210	123	All SZGR 2.0 genes in this pathway
Lee转移和替代剪接	74	51	All SZGR 2.0 genes in this pathway
Sarrio上皮间质转变	180	114	All SZGR 2.0 genes in this pathway
FUJII YBX1 TARGETS DN	202	132	All SZGR 2.0 genes in this pathway
Dairkee Cancer俯卧反应BPA E2	118	65	All SZGR 2.0 genes in this pathway
MOLENAAR TARGETS OF CCND1 AND CDK4 DN	58	25	All SZGR 2.0 genes in this pathway
Smid乳腺癌基础	648	398	All SZGR 2.0 genes in this pathway
WHITEFORD PEDIATRIC CANCER MARKERS	116	63	All SZGR 2.0 genes in this pathway
级结肠癌	871	505	All SZGR 2.0 genes in this pathway
GRADE COLON AND RECTAL CANCER UP	285	167	All SZGR 2.0 genes in this pathway
ERBB2 CDC25A的射线肿瘤发生	104	57	All SZGR 2.0 genes in this pathway
LEE LIVER CANCER SURVIVAL DN	175	103	All SZGR 2.0 genes in this pathway
HELLEBREKERS SILENCED DURING TUMOR ANGIOGENESIS	80	56	All SZGR 2.0 genes in this pathway
FRASOR RESPONSE TO SERM OR FULVESTRANT DN	50	29	All SZGR 2.0 genes in this pathway
RUIZ TNC TARGETS DN	142	79	All SZGR 2.0 genes in this pathway
CHANG CORE SERUM RESPONSE UP	212	128	All SZGR 2.0 genes in this pathway
张TLX目标60小时DN	277	166	All SZGR 2.0 genes in this pathway
Croonquist IL6剥夺DN	98	69	All SZGR 2.0 genes in this pathway
CROONQUIST NRAS SIGNALING DN	72	47	All SZGR 2.0 genes in this pathway
Croonquist NRA与基质刺激DN	99	65	All SZGR 2.0 genes in this pathway
ISHIDA E2F TARGETS	53	27	All SZGR 2.0 genes in this pathway
Kobayashi EGFR信令24小时DN	251	151	All SZGR 2.0 genes in this pathway
FOURNIER ACINAR DEVELOPMENT LATE 2	277	172	All SZGR 2.0 genes in this pathway
CAIRO HEPATOBLASTOMA CLASSES UP	605	377	All SZGR 2.0 genes in this pathway
由MYC约束	1103	714	All SZGR 2.0 genes in this pathway
WONG EMBRYONIC STEM CELL CORE	335	193	All SZGR 2.0 genes in this pathway
CDKN1A通过TP53的WU凋亡	55	31	All SZGR 2.0 genes in this pathway
Chicas RB1靶向衰老	572	352	All SZGR 2.0 genes in this pathway
Chicas RB1目标增长	243	155	All SZGR 2.0 genes in this pathway
WANG RESPONSE TO GSK3 INHIBITOR SB216763 DN	374	217	All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 6HR UP	229	149	All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR UP	324	193	All SZGR 2.0 genes in this pathway
WIERENGA PML INTERACTOME	42	23	All SZGR 2.0 genes in this pathway
BHAT ESR1 TARGETS VIA AKT1 UP	281	183	All SZGR 2.0 genes in this pathway
Lee BMP2靶向DN	882	538	All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向DN	553	343	All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP	570	339	All SZGR 2.0 genes in this pathway
WAKABAYASHI ADIPOGENESIS PPARG RXRA BOUND 8D	882	506	All SZGR 2.0 genes in this pathway
IR响应6小时中的周细胞周期基因	85	49	All SZGR 2.0 genes in this pathway
24小时IR响应中的周细胞周期基因	128	73	All SZGR 2.0 genes in this pathway

Gene Page:MCM7