基因页：MT2A

Summary？
基因 4502
象征 MT2A
Synonyms MT2
Description 金属硫蛋白2a
Reference MIM：156360|HGNC：HGNC：7406|HPRD：08863|
基因类型 蛋白质编码
Map location 16Q13
Sherlock p-value 0.432
胎儿β -2.438

Gene in Data Sources
基因集名称 Method of gene set Description 信息
简历：PGCNP 全基因组协会研究 GWAS
PMID：cooccur High-throughput literature-search PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias 点击显示详细信息

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达（GTEX）

无法使用

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

前10个积极共表达的基因
Gene 皮尔逊的相关性 斯皮尔曼的相关性
DLD 0.81 0.81
DNAJC7 0.80 0.81
PSMD12 0.80 0.80
SYAP1 0.79 0.77
DNAJC21 0.79 0.80
HDHD2 0.79 0.77
税务1BP1 0.78 0.77
USO1 0.78 0.77
SBDS 0.78 0.79
rabggtb 0.78 0.79
前10个负共表达基因
Gene 皮尔逊的相关性 斯皮尔曼的相关性
Cldn5 -0.51 -0.51
CLEC3B -0.51 -0.56
AF347015.21 -0.50 -0.24
IL32 -0.49 -0.32
ifi27 -0.46 -0.35
AF347015.2 -0.46 -0.27
TMEM88 -0.46 -0.49
Metrn -0.45 -0.38
NDUFA4L2 -0.45 -0.40
HIGD1B -0.44 -0.30

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
PID AP1途径 70 60 All SZGR 2.0 genes in this pathway
REACTOME INTERFERON GAMMA SIGNALING 63 48 All SZGR 2.0 genes in this pathway
Reactome干扰素信号传导 159 116 All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933 616 All SZGR 2.0 genes in this pathway
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM 270 204 All SZGR 2.0 genes in this pathway
Onken Uveal黑色素瘤 783 507 All SZGR 2.0 genes in this pathway
Deurig t细胞促进性白血病DN 320 184 All SZGR 2.0 genes in this pathway
刘cmyb靶向 165 106 All SZGR 2.0 genes in this pathway
乳腺癌腔与基础DN 455 304 All SZGR 2.0 genes in this pathway
Basaki YBX1靶向 290 177 All SZGR 2.0 genes in this pathway
Wang LMO4靶向 372 227 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN 275 168 All SZGR 2.0 genes in this pathway
runx1 runx1t1融合单核细胞的TONKS目标 204 140 All SZGR 2.0 genes in this pathway
Dittmer PTHLH靶向DN 73 51 All SZGR 2.0 genes in this pathway
Gozgit ESR1靶向DN 781 465 All SZGR 2.0 genes in this pathway
贝伦耶诺（Berenjeno）由rhoa转变 8 6 All SZGR 2.0 genes in this pathway
Lindgren膀胱癌簇2A DN 141 84 All SZGR 2.0 genes in this pathway
Markey RB1急性lof 215 137 All SZGR 2.0 genes in this pathway
Graessmann血清剥夺DN的细胞凋亡 234 147 All SZGR 2.0 genes in this pathway
Graessmann对MC和血清剥夺DN的反应 84 54 All SZGR 2.0 genes in this pathway
Berenjeno由Rhoa DN转变 394 258 All SZGR 2.0 genes in this pathway
MCBRYAN发育期乳房6 7周DN 79 54 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL TGFB1 TARGETS DN 62 44 All SZGR 2.0 genes in this pathway
KAN RESPONSE TO ARSENIC TRIOXIDE 123 80 All SZGR 2.0 genes in this pathway
Rodrigues NTN1和DCC目标 35 25 All SZGR 2.0 genes in this pathway
HUMMERICH SKIN CANCER PROGRESSION UP 88 58 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392 251 All SZGR 2.0 genes in this pathway
埃尔南德斯有丝分裂逮捕Docetaxel 2 Up 64 45 All SZGR 2.0 genes in this pathway
SASAKI TARGETS OF TP73 AND TP63 11 7 All SZGR 2.0 genes in this pathway
Martoriati MDM4靶向神经上皮 176 111 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER UP 227 137 All SZGR 2.0 genes in this pathway
Karakas TGFB1信号传导 18 15 All SZGR 2.0 genes in this pathway
Nuytten Nipp1靶向 769 437 All SZGR 2.0 genes in this pathway
Nuytten EZH2靶向 1037 673 All SZGR 2.0 genes in this pathway
Nakayama FRA2目标 43 27 All SZGR 2.0 genes in this pathway
洛佩兹MBD目标 957 597 All SZGR 2.0 genes in this pathway
CAFFAREL RESPONSE TO THC 24HR 3 DN 13 8 All SZGR 2.0 genes in this pathway
Caffarel对THC 24小时5 DN的响应 59 35 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487 286 All SZGR 2.0 genes in this pathway
WU细胞迁移 184 114 All SZGR 2.0 genes in this pathway
PASQUALUCCI LYMPHOMA BY GC STAGE UP 283 177 All SZGR 2.0 genes in this pathway
Benporath Myc Max目标 775 494 All SZGR 2.0 genes in this pathway
Amit EGF响应480 HELA 164 118 All SZGR 2.0 genes in this pathway
ROZANOV MMP14 TARGETS DN 35 22 All SZGR 2.0 genes in this pathway
LE EGR2目标DN 108 84 All SZGR 2.0 genes in this pathway
Houstis Ros 36 29 All SZGR 2.0 genes in this pathway
彭亮氨酸剥夺 142 93 All SZGR 2.0 genes in this pathway
Shepard BMYB Morpholino DN 200 112 All SZGR 2.0 genes in this pathway
Lee Liver Cancer Myc TGFA UP 61 40 All SZGR 2.0 genes in this pathway
Shepard BMYB目标 74 41 All SZGR 2.0 genes in this pathway
Shepard粉碎和燃烧突变体DN 185 111 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER ACOX1 UP 64 40 All SZGR 2.0 genes in this pathway
Lee Liver Cancer Myc DN 63 40 All SZGR 2.0 genes in this pathway
李肝癌电抗 60 42 All SZGR 2.0 genes in this pathway
纳德勒肥胖 61 34 All SZGR 2.0 genes in this pathway
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN 73 47 All SZGR 2.0 genes in this pathway
Galindo对肠毒素的免疫反应 85 67 All SZGR 2.0 genes in this pathway
Nemeth炎症反应LPS 88 64 All SZGR 2.0 genes in this pathway
iglesias e2f目标dn 16 11 All SZGR 2.0 genes in this pathway
Sesto对UV C8的反应 72 56 All SZGR 2.0 genes in this pathway
Schlingemann皮肤致癌作用TPA 42 24 All SZGR 2.0 genes in this pathway
伊万诺娃造血晚期祖先 544 307 All SZGR 2.0 genes in this pathway
糖尿病性肾病 86 48 All SZGR 2.0 genes in this pathway
阿尔茨海默氏症疾病 1691 1088 All SZGR 2.0 genes in this pathway
dazard对UV SCC DN的响应 123 86 All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP 103 69 All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS DN 215 132 All SZGR 2.0 genes in this pathway
大脑衰老 262 186 All SZGR 2.0 genes in this pathway
Zheng对砷的反应 18 14 All SZGR 2.0 genes in this pathway
麦克拉克兰牙齿龋齿DN 245 144 All SZGR 2.0 genes in this pathway
被胰岛素抵抗钝化的sartipy 19 17 All SZGR 2.0 genes in this pathway
BACOLOD RESISTANCE TO ALKYLATING AGENTS UP 26 17 All SZGR 2.0 genes in this pathway
Sasson FSH响应 9 6 All SZGR 2.0 genes in this pathway
约瑟夫对丁酸钠的反应 31 21 All SZGR 2.0 genes in this pathway
MCLACHLAN DENTAL CARIES UP 253 147 All SZGR 2.0 genes in this pathway
durchdewald皮肤致癌 88 47 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 4 307 185 All SZGR 2.0 genes in this pathway
TUOMISTO TUMOR SUPPRESSION BY COL13A1 UP 18 9 All SZGR 2.0 genes in this pathway
FOSTER TOLERANT MACROPHAGE DN 409 268 All SZGR 2.0 genes in this pathway
Heller HDAC靶向 317 208 All SZGR 2.0 genes in this pathway
Heller HDAC靶向被甲基化的沉默 461 298 All SZGR 2.0 genes in this pathway
马丁内斯RB1靶向 673 430 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593 372 All SZGR 2.0 genes in this pathway
Martinez RB1和TP53靶向DN 591 366 All SZGR 2.0 genes in this pathway
MASSARWEH TAMOXIFEN RESISTANCE DN 258 160 All SZGR 2.0 genes in this pathway
Sarrio上皮间质转变 180 114 All SZGR 2.0 genes in this pathway
阿塞维多肝癌DN 540 340 All SZGR 2.0 genes in this pathway
阿塞维多肝肿瘤与正常的邻近组织DN 274 165 All SZGR 2.0 genes in this pathway
Izadpanah干细胞脂肪与骨头 126 92 All SZGR 2.0 genes in this pathway
Zheng胶质母细胞瘤可塑性 250 168 All SZGR 2.0 genes in this pathway
Bochkis foxa2目标 425 261 All SZGR 2.0 genes in this pathway
拉BBE TGFB1 TARGETS DN 108 64 All SZGR 2.0 genes in this pathway
拉BBE TARGETS OF TGFB1 AND WNT3A DN 108 68 All SZGR 2.0 genes in this pathway
西肾上腺皮质肿瘤DN 546 362 All SZGR 2.0 genes in this pathway
Mirlet7a3 DN的Brueckner目标 78 49 All SZGR 2.0 genes in this pathway
Mootha PGC 420 269 All SZGR 2.0 genes in this pathway
路德维切克治疗铁超负荷 7 5 All SZGR 2.0 genes in this pathway
Piontek PKD1靶向 38 24 All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE 346 192 All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE 35D UP 131 79 All SZGR 2.0 genes in this pathway
RUTELLA RESPONSE TO CSF2RB AND IL4 DN 315 201 All SZGR 2.0 genes in this pathway
Rutella对HGF的反应 418 282 All SZGR 2.0 genes in this pathway
Rutella对HGF与CSF2RB和IL4的反应 408 276 All SZGR 2.0 genes in this pathway
甜肺癌克拉斯 491 316 All SZGR 2.0 genes in this pathway
甜Kras致癌签名 89 56 All SZGR 2.0 genes in this pathway
4EBP1和4EBP2的COLINA目标 356 214 All SZGR 2.0 genes in this pathway
Hsiao家政基因 389 245 All SZGR 2.0 genes in this pathway
Meissner NPC HCP带有H3K4ME2 491 319 All SZGR 2.0 genes in this pathway
Fournier腺泡开发2 277 172 All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤PCA3 80 54 All SZGR 2.0 genes in this pathway
Hoshida肝癌亚类S3 266 180 All SZGR 2.0 genes in this pathway
由MYC约束 1103 714 All SZGR 2.0 genes in this pathway
Chicas RB1靶向低血清 100 51 All SZGR 2.0 genes in this pathway
Qi缺氧 140 96 All SZGR 2.0 genes in this pathway
figueroa aml甲基化簇3 170 97 All SZGR 2.0 genes in this pathway
figueroa aml甲基化簇4 112 64 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 6 UP 140 81 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 7 UP 118 68 All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向 682 433 All SZGR 2.0 genes in this pathway
Smad2或Smad3的Koinuma目标 824 528 All SZGR 2.0 genes in this pathway
ERBB2同工4的PEDERSEN转移4 110 66 All SZGR 2.0 genes in this pathway
Guillaumond KLF10靶向 51 39 All SZGR 2.0 genes in this pathway
PECE MAMMARY STEM CELL UP 146 75 All SZGR 2.0 genes in this pathway
Altemeier对LPS具有机械通气的反应 128 81 All SZGR 2.0 genes in this pathway
前列腺癌模型DN中的Acevedo FGFR1靶标 308 187 All SZGR 2.0 genes in this pathway
DURAND STROMA NS UP 162 103 All SZGR 2.0 genes in this pathway
ghandhi直接辐照 110 68 All SZGR 2.0 genes in this pathway