Gene Page:MTTP

Summary?
GeneID 4547
Symbol MTTP
Synonyms ABL|MTP
Description microsomal triglyceride transfer protein
Reference MIM:157147|HGNC:HGNC:7467|Ensembl:ENSG00000138823|HPRD:01144|Vega:OTTHUMG00000131023
Gene type protein-coding
Map location 4q24
Pascal p-value 0.593
Fetal beta 0.269
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search Co-occurance患有精神分裂症keywords: schizophrenia,schizophrenic,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs17107208 chr1 52884681 MTTP 4547 0.06 trans
rs12060661 chr1 218238494 MTTP 4547 0 trans
snp_a-1809764 0 MTTP 4547 0.12 trans
rs10489958 chr1 221202661 MTTP 4547 0.14 trans
rs10196529 chr2 22475979 MTTP 4547 0.14 trans
rs13409526 chr2 22508913 MTTP 4547 0.14 trans
rs12617962 chr2 86513101 MTTP 4547 0.11 trans
rs17023999 chr2 100951590 MTTP 4547 0.08 trans
rs10168656 chr2 146923444 MTTP 4547 0.1 trans
rs7608936 chr2 146933933 MTTP 4547 0.1 trans
rs13387176 chr2 167403516 MTTP 4547 0 trans
rs17613002 chr2 221571132 MTTP 4547 0.07 trans
rs16861747 chr2 221643239 MTTP 4547 0.02 trans
rs16861754 chr2 221643553 MTTP 4547 0.12 trans
rs16861756 chr2 221643602 MTTP 4547 0.04 trans
rs1510514 chr2 239436367 MTTP 4547 4.374E-4 trans
rs179852 chr3 172328734 MTTP 4547 0.01 trans
rs4544747 chr4 179527501 MTTP 4547 0.11 trans
rs3911341 chr5 33328176 MTTP 4547 0.2 trans
rs7709525 chr5 33333510 MTTP 4547 0.06 trans
rs16896739 chr5 66716605 MTTP 4547 0.04 trans
rs6862696 chr5 66724676 MTTP 4547 0.01 trans
rs7734355 chr5 102747929 MTTP 4547 0.02 trans
rs4958094 chr5 133001523 MTTP 4547 0.15 trans
rs9378305 chr6 1703289 MTTP 4547 0.18 trans
rs9503011 chr6 1704149 MTTP 4547 0.18 trans
rs4052671 chr6 24223578 MTTP 4547 0.13 trans
rs17057213 chr6 97459552 MTTP 4547 0.04 trans
rs7748086 chr6 97471138 MTTP 4547 0.04 trans
rs6949211 chr7 11231070 MTTP 4547 0.14 trans
rs17160028 chr7 31292738 MTTP 4547 0 trans
rs920630 chr8 26448752 MTTP 4547 0 trans
rs17055486 chr8 26449410 MTTP 4547 0 trans
rs7001738 chr8 26455799 MTTP 4547 0.05 trans
rs17782229 chr8 33937315 MTTP 4547 0.03 trans
rs2513956 chr8 98838200 MTTP 4547 0.08 trans
snp_a-1838941 0 MTTP 4547 0.06 trans
snp_a-1822068 0 MTTP 4547 0.15 trans
rs538066 chr9 130494956 MTTP 4547 0.12 trans
rs17093688 chr9 137170563 MTTP 4547 0.06 trans
rs16924738 chr10 24712202 MTTP 4547 0.19 trans
rs11005510 chr10 58532988 MTTP 4547 0.01 trans
rs16909905 chr10 58740538 MTTP 4547 0.15 trans
rs17099339 chr10 83832303 MTTP 4547 0.18 trans
rs540477 chr10 100315774 MTTP 4547 0.01 trans
rs628037 chr10 100325514 MTTP 4547 0.03 trans
rs1381549 chr10 100332800 MTTP 4547 0.03 trans
rs10736134 chr10 100344123 MTTP 4547 0.1 trans
rs3866908 chr10 100347967 MTTP 4547 0.07 trans
rs675410 chr10 100350321 MTTP 4547 0.03 trans
rs12244614 chr10 100353615 MTTP 4547 0.03 trans
rs12294434 chr11 12265082 MTTP 4547 0.03 trans
rs2283252 chr11 17520964 MTTP 4547 0.11 trans
rs7941111 chr11 112562626 MTTP 4547 0.1 trans
rs7953173 chr12 44488755 MTTP 4547 0.05 trans
rs17042851 chr12 77469962 MTTP 4547 1.599E-4 trans
rs10732643 chr12 89162114 MTTP 4547 0.06 trans
rs12309615 chr12 98585947 MTTP 4547 0.05 trans
rs7304029 chr12 120295224 MTTP 4547 0.07 trans
rs7988137 chr13 20682078 MTTP 4547 0.16 trans
rs2313862 chr13 20933817 MTTP 4547 0 trans
rs3961328 chr13 25516431 MTTP 4547 0.1 trans
rs954547 chr13 41039976 MTTP 4547 0.11 trans
rs2137842 chr13 61344861 MTTP 4547 0.05 trans
rs17750196 chr15 29741278 MTTP 4547 0.06 trans
rs882396 chr15 37194830 MTTP 4547 0.1 trans
rs2415151 chr15 73723264 MTTP 4547 0.02 trans
rs17650617 chr15 93867698 MTTP 4547 0.08 trans
rs2240690 chr16 2026441 MTTP 4547 0.16 trans
rs9946000 chr18 44296318 MTTP 4547 0 trans
rs16940060 chr18 44348819 MTTP 4547 0 trans
rs6133799 chr20 10086798 MTTP 4547 0.12 trans
rs12556858 chrX 93352570 MTTP 4547 0.02 trans
rs12556892 chrX 93417735 MTTP 4547 0 trans
rs808754 chrX 93438033 MTTP 4547 0 trans
rs5930726 chrX 134658726 MTTP 4547 0.13 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
REACTOME METABOLISM OF LIPIDS AND LIPOPROTEINS 478 302 All SZGR 2.0 genes in this pathway
REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT 46 37 All SZGR 2.0 genes in this pathway
REACTOME LIPOPROTEIN METABOLISM 28 24 All SZGR 2.0 genes in this pathway
REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT 16 15 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367 220 All SZGR 2.0 genes in this pathway
SANSOM APC TARGETS DN 366 238 All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES 244 154 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN 274 165 All SZGR 2.0 genes in this pathway
CADWELL ATG16L1 TARGETS UP 93 56 All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION DN 179 97 All SZGR 2.0 genes in this pathway
WOO LIVER CANCER RECURRENCE DN 80 54 All SZGR 2.0 genes in this pathway
OHGUCHI LIVER HNF4A TARGETS DN 149 85 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B 549 316 All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682 433 All SZGR 2.0 genes in this pathway