Gene Page:ATF3

年代ummary？
基因 467
象征 ATF3
年代ynonyms -
Description activating transcription factor 3
Reference MIM:603148|HGNC：HGNC：785|ENSEMBL：ENSG00000162772|HPRD：04395|Vega：Otthumg0000000036747
基因类型 蛋白质编码
Map location 1q32.3
胎儿β -2.398
DMG 1(# studies)
主持人 Myers' cis & trans

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp Genome-wide Association Study GWAS
DMG：JAFFE_2016 全基因组DNA甲基化分析 该数据集包括与SZ患者相关的2,104个探针/CPG（n = 108），而在Bonferroni调整后的P <0.05时，其中136个对照。 1
PMID：cooccur High-throughput literature-search PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature High-throughput literature-search Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias 点击显示详细信息

年代ection I. Genetics and epigenetics annotation

@差异甲基化基因

Probe 染色体 位置 最近的基因 p（dis） Beta (dis) fdr（dis） 学习
cg03900353 1 212732456 ATF3 1.84e-10 -0.037 5.29E-7 DMG：JAFFE_2016

@eQTL annotation

SNP ID 染色体 位置 主持人 Gene Entrez ID pvalue QVALUE TSS距离 EQTL类型
rs1507047 CHR16 50932778 ATF3 467 0.1 反式

第二节。转录组注释

一般基因表达（GTEX）

Not available

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions


年代ection V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
PID SMAD2 3核途径 82 63 All SZGR 2.0 genes in this pathway
PID P53 DOWNSTREAM PATHWAY 137 94 All SZGR 2.0 genes in this pathway
PID ATF2 PATHWAY 59 43 All SZGR 2.0 genes in this pathway
PID AP1 PATHWAY 70 60 All SZGR 2.0 genes in this pathway
Reactome糖尿病途径 133 91 All SZGR 2.0 genes in this pathway
Reactome Perk调控基因表达 29 14 All SZGR 2.0 genes in this pathway
REACTOME ACTIVATION OF GENES BY ATF4 26 12 All SZGR 2.0 genes in this pathway
REACTOME UNFOLDED PROTEIN RESPONSE 80 51 All SZGR 2.0 genes in this pathway
KIM RESPONSE TO TSA AND DECITABINE UP 129 73 All SZGR 2.0 genes in this pathway
Zerbini对Sulindac的反应 9 6 All SZGR 2.0 genes in this pathway
ZHONG RESPONSE TO AZACITIDINE AND TSA UP 183 119 All SZGR 2.0 genes in this pathway
turashvili乳房正常导管与小叶 68 40 All SZGR 2.0 genes in this pathway
turashvili乳房导管癌与导管正常DN 198 110 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN 69 43 All SZGR 2.0 genes in this pathway
HOOI ST7靶向 94 57 All SZGR 2.0 genes in this pathway
deurig t细胞促进性白血病 368 234 All SZGR 2.0 genes in this pathway
Horiuchi WTAP靶向 306 188 All SZGR 2.0 genes in this pathway
胶原蛋白凝胶中的Oswald造血干细胞 233 161 All SZGR 2.0 genes in this pathway
Gargalovic对氧化磷脂的反应蓝色 136 80 All SZGR 2.0 genes in this pathway
UDayakumar Med1靶向DN 240 171 All SZGR 2.0 genes in this pathway
年代ENESE HDAC3 TARGETS UP 501 327 All SZGR 2.0 genes in this pathway
Tien肠益生菌24小时DN 214 133 All SZGR 2.0 genes in this pathway
Nagashima NRG1信号向上发出 176 123 All SZGR 2.0 genes in this pathway
Nagashima EGF信号向上 58 40 All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA UP 171 112 All SZGR 2.0 genes in this pathway
DMOG的Elvidge缺氧 130 85 All SZGR 2.0 genes in this pathway
HAHTOLA MYCOSIS FUNGOIDES CD4 UP 64 46 All SZGR 2.0 genes in this pathway
ENK UV响应表皮DN 508 354 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE UP 530 342 All SZGR 2.0 genes in this pathway
chiaradonna肿瘤转化Kras DN 142 95 All SZGR 2.0 genes in this pathway
berenjeno岩石信号不是通过Rhoa Up 29 21 All SZGR 2.0 genes in this pathway
VANHARANTA UTERINE FIBROID DN 67 45 All SZGR 2.0 genes in this pathway
CONCANNON APOPTOSIS BY EPOXOMICIN UP 239 157 All SZGR 2.0 genes in this pathway
阿霉素的Graessmann凋亡 1142 669 All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS A DN 90 61 All SZGR 2.0 genes in this pathway
MISSIAGLIA REGULATED BY METHYLATION UP 126 78 All SZGR 2.0 genes in this pathway
王食道癌与正常 121 72 All SZGR 2.0 genes in this pathway
KAN RESPONSE TO ARSENIC TRIOXIDE 123 80 All SZGR 2.0 genes in this pathway
MAHADEVAN RESPONSE TO MP470 DN 19 11 All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 1 45 27 All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 2 127 92 All SZGR 2.0 genes in this pathway
Dauer Stat3靶向 49 35 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 UP 309 199 All SZGR 2.0 genes in this pathway
Amundson对砷的回应 217 143 All SZGR 2.0 genes in this pathway
Borlak肝癌EGF UP 57 41 All SZGR 2.0 genes in this pathway
王HCP前列腺癌 111 69 All SZGR 2.0 genes in this pathway
Gruetzmann胰腺癌 358 245 All SZGR 2.0 genes in this pathway
WATTEL AUTONOMOUS THYROID ADENOMA DN 55 29 All SZGR 2.0 genes in this pathway
Sheth肝癌与TXNIP损失PAM2 153 102 All SZGR 2.0 genes in this pathway
通过ELK3 DN的缺氧总缺氧 156 106 All SZGR 2.0 genes in this pathway
通过HIF1A DN的缺氧总缺氧 110 78 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 AND HIF1A UP 142 104 All SZGR 2.0 genes in this pathway
Nuytten Nipp1靶向 769 437 All SZGR 2.0 genes in this pathway
Nuytten EZH2靶向 1037 673 All SZGR 2.0 genes in this pathway
buytaert光动力疗法压力 811 508 All SZGR 2.0 genes in this pathway
年代CIAN INVERSED TARGETS OF TP53 AND TP73 DN 31 23 All SZGR 2.0 genes in this pathway
阿米特延迟了早期基因 18 15 All SZGR 2.0 genes in this pathway
Benporath SOX2目标 734 436 All SZGR 2.0 genes in this pathway
Benporath Suz12目标 1038 678 All SZGR 2.0 genes in this pathway
Benporath EED目标 1062 725 All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway
Benporath PRC2目标 652 441 All SZGR 2.0 genes in this pathway
Amit EGF响应40 HELA 42 29 All SZGR 2.0 genes in this pathway
AMIT SERUM RESPONSE 40 MCF10A 32 21 All SZGR 2.0 genes in this pathway
张IKK抑制剂和肿瘤坏死因子 223 140 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 UP 140 85 All SZGR 2.0 genes in this pathway
Shepard粉碎和燃烧突变体 197 110 All SZGR 2.0 genes in this pathway
史密斯·泰特（Smith Tert） 145 91 All SZGR 2.0 genes in this pathway
KANNAN TP53 TARGETS UP 58 40 All SZGR 2.0 genes in this pathway
Jechlinger上皮到间充质转变DN 66 47 All SZGR 2.0 genes in this pathway
LE EGR2 TARGETS UP 108 75 All SZGR 2.0 genes in this pathway
ADDYA ERYTHROID DIFFERENTIATION BY HEMIN 73 47 All SZGR 2.0 genes in this pathway
Nemeth炎症反应LPS 88 64 All SZGR 2.0 genes in this pathway
ZHAN MULTIPLE MYELOMA UP 64 46 All SZGR 2.0 genes in this pathway
GERY CEBP TARGETS 126 90 All SZGR 2.0 genes in this pathway
量缺氧 98 71 All SZGR 2.0 genes in this pathway
Iyengar对脂肪细胞因子的反应 10 8 All SZGR 2.0 genes in this pathway
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP 314 201 All SZGR 2.0 genes in this pathway
马丁内斯对trabectedin的反应 71 49 All SZGR 2.0 genes in this pathway
布朗HCMV感染48小时 180 125 All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP 103 69 All SZGR 2.0 genes in this pathway
GAJATE RESPONSE TO TRABECTEDIN UP 67 45 All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV NHEK UP 244 151 All SZGR 2.0 genes in this pathway
GENTILE UV HIGH DOSE DN 312 203 All SZGR 2.0 genes in this pathway
外邦紫外线高剂量 25 13 All SZGR 2.0 genes in this pathway
盖斯对dsrna的响应 38 29 All SZGR 2.0 genes in this pathway
敏锐的回应罗格列酮DN 106 68 All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV SCC UP 123 75 All SZGR 2.0 genes in this pathway
Varela ZMPSTE24目标 40 30 All SZGR 2.0 genes in this pathway
年代ATO SILENCED BY DEACETYLATION IN PANCREATIC CANCER 50 30 All SZGR 2.0 genes in this pathway
Sesto对UV C3的反应 20 15 All SZGR 2.0 genes in this pathway
LEE AGING MUSCLE UP 45 33 All SZGR 2.0 genes in this pathway
DAZARD UV RESPONSE CLUSTER G2 30 18 All SZGR 2.0 genes in this pathway
磷酸氨基酸剥夺 29 20 All SZGR 2.0 genes in this pathway
Krige对Tosedostat 6小时的反应 953 554 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783 442 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON UP 77 47 All SZGR 2.0 genes in this pathway
海勒被甲基化DN沉默 105 67 All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS DN 292 189 All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION DN 281 179 All SZGR 2.0 genes in this pathway
Martinez RB1靶向DN 543 317 All SZGR 2.0 genes in this pathway
Martinez TP53靶向 602 364 All SZGR 2.0 genes in this pathway
Martinez RB1和TP53靶向 601 369 All SZGR 2.0 genes in this pathway
年代ARRIO EPITHELIAL MESENCHYMAL TRANSITION DN 154 101 All SZGR 2.0 genes in this pathway
OSADA ASCL1靶向 46 30 All SZGR 2.0 genes in this pathway
SAGIV CD24目标DN 46 26 All SZGR 2.0 genes in this pathway
Boquest干细胞培养与新鲜 425 298 All SZGR 2.0 genes in this pathway
CHO NR4A1 TARGETS 33 22 All SZGR 2.0 genes in this pathway
podar对Apaphostin的反应 147 98 All SZGR 2.0 genes in this pathway
Chen Hoxa5靶向9小时 223 132 All SZGR 2.0 genes in this pathway
对Salirasib的反应 245 159 All SZGR 2.0 genes in this pathway
CCND1 MYC的王肿瘤转化 21 14 All SZGR 2.0 genes in this pathway
法拉利对fenretinide的反应 22 16 All SZGR 2.0 genes in this pathway
Lindstedt树突状细胞成熟C 69 49 All SZGR 2.0 genes in this pathway
Hofmann骨髓增生综合征低风险 22 15 All SZGR 2.0 genes in this pathway
CHEN METABOLIC SYNDROM NETWORK 1210 725 All SZGR 2.0 genes in this pathway
骨髓瘤与成熟B淋巴细胞中的Shaffer IRF4靶标 101 76 All SZGR 2.0 genes in this pathway
浆细胞与成熟B淋巴细胞中的Shaffer IRF4靶标 67 51 All SZGR 2.0 genes in this pathway
Meissner Brain HCP带有H3K4ME3和H3K27ME3 1069 729 All SZGR 2.0 genes in this pathway
Valk AML群集1 28 19 All SZGR 2.0 genes in this pathway
Jison Sickle细胞疾病 181 106 All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤PCA3 80 54 All SZGR 2.0 genes in this pathway
Uzonyi对白三烯和凝血酶的反应 37 26 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway
钱德兰转移DN 306 191 All SZGR 2.0 genes in this pathway
YAO对孕酮簇5的时间反应5 30 22 All SZGR 2.0 genes in this pathway
中村脂肪形成晚期 104 67 All SZGR 2.0 genes in this pathway
dazard UV响应集群G28 20 11 All SZGR 2.0 genes in this pathway
Browne HCMV感染2小时 39 30 All SZGR 2.0 genes in this pathway
年代UBTIL PROGESTIN TARGETS 36 25 All SZGR 2.0 genes in this pathway
BHAT ESR1 TARGETS VIA AKT1 UP 281 183 All SZGR 2.0 genes in this pathway
Bruins通过TP53组A的UVC响应 898 516 All SZGR 2.0 genes in this pathway
Dalessio TSA响应 29 16 All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS UP 682 433 All SZGR 2.0 genes in this pathway
Smad2或Smad3的Koinuma目标 824 528 All SZGR 2.0 genes in this pathway
Gobert少突胶质细胞分化DN 1080 713 All SZGR 2.0 genes in this pathway
Servitja Islet HNF1A靶向 163 111 All SZGR 2.0 genes in this pathway
Delacroix Rar Bound ES 462 273 All SZGR 2.0 genes in this pathway
phong TNF靶向 63 43 All SZGR 2.0 genes in this pathway
通过p38完成的phong TNF响应 227 151 All SZGR 2.0 genes in this pathway
Altemeier对LPS具有机械通气的反应 128 81 All SZGR 2.0 genes in this pathway
Smirnov对IR 2小时的回应 53 33 All SZGR 2.0 genes in this pathway
年代MIRNOV RESPONSE TO IR 6HR UP 166 97 All SZGR 2.0 genes in this pathway
WARTERS红外响应5GY 47 23 All SZGR 2.0 genes in this pathway
Zwang 3类由EGF瞬时诱导 222 159 All SZGR 2.0 genes in this pathway