SZGR2 - Beplay体育中心

Summary？

基因	4790
Symbol	NFKB1
Synonyms	CVID12\|EBP-1\|KBF1\|NF-kB1\|NF-kappa-B\|NF-kappaB\|NFKB-p105\|NFKB-p50\|NFkappaB\|p105\|p50
Description	B细胞中Kappa光多肽基因增强子的核因子1
Reference	MIM：164011\|HGNC:HGNC:7794\|Ensembl:ENSG00000109320\|HPRD：01238\|Vega:OTTHUMG00000161080
Gene type	蛋白质编码
Map location	4Q24
Pascal p-value	0.113
Sherlock p-value	0.112
胎儿β	-0.303
Support	Ascano FMRP targets

Gene in Data Sources

Gene set name	Method of gene set	Description	信息
CV:GWAScat	Genome-wide Association Studies	该数据集包括与精神分裂症相关的560个SNP。总共将486个基因映射到50kb内的这些SNP。
CV:GWASdb	Genome-wide Association Studies	GWASdb records for schizophrenia
CV:PGCnp	Genome-wide Association Study	GWAS
PMID：cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias	点击显示详细信息
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 0.0798

Section I. Genetics and epigenetics annotation

第二节。转录组注释

一般基因表达（GTEX）

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

前10个积极共表达的基因
Gene	Pearson's Correlation	Spearman's Correlation
OLIG1	0.82	0.89
OLIG2	0.81	0.86
SOX10	0.75	0.87
HEPACAM	0.71	0.81
ZCCHC24	0.71	0.81
NFATC1	0.70	0.67
CHAD	0.70	0.77
SLC12A4	0.69	0.63
PRR5L	0.69	0.65
CD82	0.68	0.72

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
STMN1	-0.45	-0.56
STMN2	-0.44	-0.55
MAPK8	-0.44	-0.52
POLB	-0.44	-0.59
ZNF551	-0.44	-0.52
ZNF286	-0.44	-0.49
PPP3CC	-0.43	-0.54
AC004017.1	-0.43	-0.50
Med19	-0.43	-0.56
FRG1	-0.43	-0.61

第三节。基因本体论注释

分子功能	去学期	证据	神经关键字	PubMed ID
GO:0003700	transcription factor activity	TAS		10928981
去：0005515	蛋白质结合	IPI		8196632\|11526476\|14624448 \|16108830\|16306601
生物过程	去学期	证据	神经关键字	PubMed ID
GO:0006355	调节转录，DNA依赖性的调节	IEA		-
GO:0006366	transcription from RNA polymerase II promoter	TAS		1992489
GO:0007165	信号转导	IEA		-
GO:0006954	炎症反应	TAS		1992489
GO:0006916	anti-apoptosis	TAS		10811897
GO:0006915	apoptosis	IEA		-
GO:0045941	positive regulation of transcription	NAS		8096091
Cellular component	去学期	证据	神经关键字	PubMed ID
GO:0005829	cytosol	EXP		10723127
GO:0005634	nucleus	IDA		11819787
GO:0005654	nucleoplasm	EXP		10723127
去：0005737	cytoplasm	IDA		11819787

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	实验	Source	PubMed ID
ar	AIS \| DHTR \| HUMARA \| KD \| NR3C4 \| SBMA \| SMAX1 \| TFM	雄激素受体	-	HPRD	8798655
ATF3	-	activating transcription factor 3	-	HPRD	7692236
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	p50 interacts with BCL-3. This interaction was modelled on a demonstrated interaction between p50 from an unspecified species and human BCL-3.	BIND	15469820
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	-	HPRD	10362352
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	亲和力捕获 - 韦斯特恩 Co-localization 共纯化重构的复合物	Biogrid	8428580\|10469655 \|14678988
BCL3	BCL4 \| D19S37	B-cell CLL/lymphoma 3	NFKB1(p50) interacts with BCL3.	BIND	15829968
BIRC3	AIP1 \|API2 \|CIAP2 \|haip1 \|hiap1 \|MALT2 \|mihc \|RNF49	baculoviral IAP repeat-containing 3	The cIAP-2 promoter interacts with p50.	BIND	15494311
BRCA1	BRCAI \| BRCC1 \| IRIS \| PSCP \| RNF53	乳腺癌1，早发	-	HPRD	12700228
BTRC	beta-trcp \|fbw1a \|fbxw1 \|fbxw1a \|FWD1 \|MGC4643 \|BTRCP \|BTRCP1 \|betatrcp	beta-transducin repeat containing	亲和力捕获 - 韦斯特恩	Biogrid	11158290
CD82	4F9 \| C33 \| GR15 \| IA4 \| KAI1 \| R2 \| SAR2 \| ST6 \| TSPAN27	CD82 molecule	NFKB1(p50) interacts with the CD82 (KAI1) promoter.	BIND	15829968
CDK9	C-2k \| CDC2L4 \| CTK1 \| PITALRE \| TAK	cyclin-dependent kinase 9	-	HPRD	12173051
CEBPB	C/EBP-beta \| CRP2 \| IL6DBP \| LAP \| MGC32080 \| NF-IL6 \| TCF5	CCAAT/enhancer binding protein (C/EBP), beta	-	HPRD,BioGRID	1518839
CHUK	IKBKA \| IKK-alpha \| IKK1 \| IKKA \| NFKBIKA \| TCF16	保守的螺旋环螺旋无处不在激酶	-	HPRD,BioGRID	10469655
COPB2	beta'-cop	coatomer protein complex, subunit beta 2 (beta prime)	Affinity Capture-MS	Biogrid	14743216
CTNNB1	CTNNB \| DKFZp686D02253 \| FLJ25606 \| FLJ37923	catenin (cadherin-associated protein), beta 1, 88kDa	NFKB1(p50) interacts with CTNNB1 (beta-catenin).	BIND	15829968
DSP	DPI \| DPII	脱莫普拉金	-	HPRD	14743216
E2F1	E2F-1 \|RBAP1 \|rbbp3 \|rbp3	E2F transcription factor 1	重构的复合物	Biogrid	9368006
ELF1	-	E74-like factor 1 (ets domain transcription factor)	-	HPRD,BioGRID	7862168
ELF3	EPR-1 \| ERT \| ESE-1 \| ESX	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	-	HPRD,BioGRID	11036073
ETS1	ETS-1 \| EWSR2 \| FLJ10768	V-ETS红细胞增生病毒E26癌基因同源1（Avian）	-	HPRD	9094628
fos	AP-1 \|c-fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	-	HPRD	9468519
G3BP2	-	GTPase activating protein (SH3 domain) binding protein 2	-	HPRD	10969074
GSK3B	-	糖原合酶激酶3β	-	HPRD,BioGRID	11425860
HDAC1	DKFZP686H12203 \|gon-10 \|HD1 \|RPD3 \|RPD3L1	histone deacetylase 1	-	HPRD,BioGRID	11931769
HMGA2	BABL \| HMGI-C \| HMGIC \| LIPO \| STQTL9	high mobility group AT-hook 2	-	HPRD,BioGRID	12693954
HMGB1	DKFZP686A04236 \|HMG1 \|HMG3 \|SBP-1	高机动性组框1	-	HPRD,BioGRID	12604365
HNRNPM	DKFZP547H118 \|HNRNPM4 \|HNRPM \|HNRPM4 \|htgr1 \|Nagr1	heterogeneous nuclear ribonucleoprotein M	-	HPRD	14743216
HSPA8	HSC54 \| HSC70 \| HSC71 \| HSP71 \| HSP73 \| HSPA10 \| LAP1 \| MGC131511 \| MGC29929 \| NIP71	heat shock 70kDa protein 8	-	HPRD	14743216
ikbkb	FLJ40509 \| IKK-beta \| IKK2 \| IKKB \| MGC131801 \| NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	-	HPRD	10469655 \| 11158290
ikbkb	FLJ40509 \| IKK-beta \| IKK2 \| IKKB \| MGC131801 \| NFKBIKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	亲和力捕获 - 韦斯特恩生化活动	Biogrid	10469655\|11158290
ikbkg	AMCBX1 \| FIP-3 \| FIP3 \| Fip3p \| IKK-gamma \| IP \| IP1 \| IP2 \| IPD2 \| NEMO	B细胞，激酶γ中Kappa光多肽基因增强子的抑制剂	Affinity Capture-MS	Biogrid	14743216
IL2RA	CD25 \|IDDM10 \|IL2R \|TCGFR	interleukin 2 receptor, alpha	体外 in vivo	Biogrid	2497520
IL8	CXCL8 \| GCP-1 \| GCP1 \| LECT \| LUCT \| LYNAP \| MDNCF \| MONAP \| NAF \| NAP-1 \| NAP1	interleukin 8	The IL-8 promoter interacts with p50.	BIND	15494311
IRF1	IRF-1 \| MAR	interferon regulatory factor 1	-	HPRD	8746784
IRF2	DKFZp686F0244 \| IRF-2	interferon regulatory factor 2	-	HPRD,BioGRID	8550813
ITGB3BP	CENP-R \| CENPR \| HSU37139 \| NRIF3 \| TAP20	integrin beta 3 binding protein (beta3-endonexin)	-	HPRD,BioGRID	12244126
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K（赖氨酸）乙酰转移酶5	HTATIP（TIP60）与NFKB1（p50）相互作用。	BIND	15829968
KLF5	BTEB2 \| CKLF \| IKLF	Kruppel样因子5（肠）	-	HPRD,BioGRID	14573617
KPNA3	IPOA4 \| SRP1gamma \| SRP4 \| hSRP1	karyopherin alpha 3 (importin alpha 4)	Affinity Capture-MS	Biogrid	14743216
LYL1	bHLHa18	lymphoblastic leukemia derived sequence 1	体外 in vivo Two-hybrid	Biogrid	10023675
MAP3K7IP2	FLJ21885 \| KIAA0733 \| TAB2	有丝分裂原激活的蛋白激酶激酶激酶7相互作用蛋白2	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	12150997
MAP3K8	COT \| EST \| ESTF \| FLJ10486 \| TPL2 \| Tpl-2 \| c-COT	有丝分裂原激活的蛋白激酶激酶激酶8	-	HPRD,BioGRID	9950430
MEN1	MEAI \| SCG2	多内分泌肿瘤I	-	HPRD,BioGRID	11526476
MRCL3	MLCB \| MRLC3	myosin regulatory light chain MRCL3	-	HPRD	14743216
MTPN	FLJ31098 \| FLJ99857 \| GCDP \| V-1	myotrophin	-	HPRD,BioGRID	11971907
myl6	ESMLC \|LC17-GI \|LC17-nm \|LC17A \|LC17B \|MLC1SM \|MLC3NM \|MLC3SM	myosin, light chain 6, alkali, smooth muscle and non-muscle	-	HPRD	14743216
NCF1C	SH3PXD1C	中性粒细胞胞质因子1c假基因	-	HPRD	12618429
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	核受体共激活因子1	SRC-1与P50相互作用。这种相互作用是基于未指定物种的人类SRC-1和P50之间的相互作用建模的。	BIND	9556555
NCOA1	F-SRC-1 \| KAT13A \| MGC129719 \| MGC129720 \| NCoA-1 \| RIP160 \| SRC-1 \| SRC1 \| bHLHe42	核受体共激活因子1	-	HPRD,BioGRID	9556555
NCOA6	AIB3 \| ANTP \| ASC2 \| HOX1.1 \| HOXA7 \| KIAA0181 \| NRC \| PRIP \| RAP250 \| TRBP	核受体共激活因子6	重构的复合物	Biogrid	10847592
NCOR1	KIAA1047 \| MGC104216 \| N-CoR \| TRAC1 \| hCIT529I10 \| hN-CoR	核受体共抑制剂1	亲和力捕获 - 韦斯特恩	Biogrid	12150997
NCOR2	CTG26 \| SMRT \| SMRTE \| SMRTE-tau \| TNRC14 \| TRAC-1 \| TRAC1	核受体共抑制剂2	-	HPRD	10777532
NFKB1	DKFZP686C01211 \|EBP-1 \|kbf1 \|MGC54151 \|nf-kappa-b \|NFKB-P105 \|NFKB-P50 \|P105	B细胞中Kappa光多肽基因增强子的核因子1	Affinity Capture-MS 亲和力捕获 - 韦斯特恩 Co-localization 重构的复合物	Biogrid	8428580\|14743216
NFKB1	DKFZP686C01211 \|EBP-1 \|kbf1 \|MGC54151 \|nf-kappa-b \|NFKB-P105 \|NFKB-P50 \|P105	B细胞中Kappa光多肽基因增强子的核因子1	NFKB1(p50) forms a homodimer.	BIND	15735750
NFKB1	DKFZP686C01211 \|EBP-1 \|kbf1 \|MGC54151 \|nf-kappa-b \|NFKB-P105 \|NFKB-P50 \|P105	B细胞中Kappa光多肽基因增强子的核因子1	p50 interacts with p50. This interaction was modelled on a demonstrated interaction between p50 and p50 both from an unspecified species.	BIND	9556555
NFKB2	Lyt-10 \|Lyt10	B细胞2（P49/P100）中Kappa光多肽基因增强子的核因子	Affinity Capture-MS	Biogrid	14743216
nfkbiA	ikba \|Mad-3 \|nfkbi	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	-	HPRD,BioGRID	9738011
nfkbiA	ikba \|Mad-3 \|nfkbi	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	p50 associates with I-kappa-B-alpha.	BIND	9135156
nfkbiE	ikbe	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	-	HPRD	9223487
nfkbiE	ikbe	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	亲和力捕获 - 韦斯特恩重构的复合物 Two-hybrid	Biogrid	9315679
nfkbiZ	FLJ30225 \|FLJ34463 \|ikbz \|inap \|邮件	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	亲和力捕获 - 韦斯特恩	Biogrid	11356851
nkrf	ITBA4 \| NRF	NFKB repressing factor	重构的复合物	Biogrid	10562553
NOTCH1	TAN1 \| hN1	Notch同源1，易位相关（果蝇）	-	HPRD,BioGRID	8642313\|11418662
NR3C1	GCCR \|GCR \|gr \|grl	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	-	HPRD,BioGRID	7823959\|8290595
PARP1	ADPRT \| ADPRT1 \| PARP \| PARP-1 \| PPOL \| pADPRT-1	poly (ADP-ribose) polymerase 1	-	HPRD	11590148
PPP4C	PP4 \| PPH3 \| PPX	protein phosphatase 4 (formerly X), catalytic subunit	-	HPRD,BioGRID	9837938
REL	C-Rel	V-REL网状内皮症病毒性癌基因同源物（Avian）	Affinity Capture-MS	Biogrid	14743216
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis病毒致癌基因相同器官A (avian)	Affinity Capture-MS 重构的复合物	Biogrid	8798655\|14743216
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis病毒致癌基因相同器官A (avian)	NFKB1(p50) interacts with RELA (p65).	BIND	15735750
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis病毒致癌基因相同器官A (avian)	p50 interacts with p65. This interaction was modeled on a demonstrated interaction between mouse p50 and mouse p65.	BIND	9738011
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis病毒致癌基因相同器官A (avian)	-	HPRD	8649779
RELB	I-REL \| IREL	v-rel reticuloendotheliosis病毒致癌基因相同器官B	Affinity Capture-MS	Biogrid	14743216
RSF1	HBXAP \| RSF-1 \| XAP8 \| p325	remodeling and spacing factor 1	-	HPRD,BioGRID	15242768
ruvbl2	CGI-46 \| ECP51 \| INO80J \| REPTIN \| RVB2 \| TIH2 \| TIP48 \| TIP49B	RuvB-like 2 (E. coli)	-	HPRD	14743216
ruvbl2	CGI-46 \| ECP51 \| INO80J \| REPTIN \| RVB2 \| TIH2 \| TIP48 \| TIP49B	RuvB-like 2 (E. coli)	NFKB1(p50) interacts with RUVBL2 (reptin).	BIND	15829968
RXRA	FLJ00280 \| FLJ00318 \| FLJ16020 \| FLJ16733 \| MGC102720 \| NR2B1	类维生素X受体，α	-	HPRD,BioGRID	10075655
SP1	-	Sp1 transcription factor	重构的复合物	Biogrid	7933095
SPAG9	FLJ13450 \| FLJ14006 \| FLJ26141 \| FLJ34602 \| HLC4 \|JLP \| KIAA0516 \| MGC117291 \| MGC14967 \| MGC74461 \| PHET \| PIG6	sperm associated antigen 9	-	HPRD,BioGRID	14743216
SPAG9	FLJ13450 \| FLJ14006 \| FLJ26141 \| FLJ34602 \| HLC4 \|JLP \| KIAA0516 \| MGC117291 \| MGC14967 \| MGC74461 \| PHET \| PIG6	sperm associated antigen 9	NFKB1(NF-kB1/p105) interacts with an unspecified isoform of SPAG9 (JLP).	BIND	14743216
SPI1	OF \| PU.1 \| SFPI1 \| SPI-1 \| SPI-A	脾脏焦点形成病毒（SFFV）前病毒整合Oncogene SPI1	-	HPRD	9094628
Stat3	APRF \|FLJ20882 \|hies \|MGC16063	转录3的信号换能器和激活因子（急性相反应因子）	-	HPRD,BioGRID	12057007
Stat6	D12S1644 \| IL-4-STAT \| STAT6B \| STAT6C	转录6，白介素4的信号换能器和激活剂诱导	-	HPRD,BioGRID	9584180
TBK1	FLJ11330 \| NAK \| T2K	TANK-binding kinase 1	Affinity Capture-MS	Biogrid	14743216
TNFSF11	CD254 \|ODF \|OPGL \|OPTB2 \|rankl \|tr \|hrankl2 \|SODF	tumor necrosis factor (ligand) superfamily, member 11	-	HPRD	10635328
TNIP2	Abin-2 \|Abin2 \|flip1 \|klip \|MGC4289	TNFAIP3相互作用蛋白2	-	HPRD,BioGRID	14743216\|15169888
TNIP3	ABIN-3 \| FLJ21162 \| LIND	TNFAIP3相互作用蛋白3	Affinity Capture-MS	Biogrid	14743216
TP53BP1	53BP1 \| FLJ41424 \| MGC138366 \| p202	tumor protein p53 binding protein 1	亲和力捕获 - 韦斯特恩	Biogrid	10646849
TPR	-	translocated promoter region (to activated MET oncogene)	-	HPRD	14743216
TRIP4	HsT17391	thyroid hormone receptor interactor 4	-	HPRD	12077347
TSC22D3	DIP \| DKFZp313A1123 \| DSIPI \| GILZ \| TSC-22R \| hDIP	TSC22 domain family, member 3	-	HPRD,BioGRID	11468175
tuba3c	TUBA2 \| bA408E5.3	tubulin, alpha 3c	-	HPRD	14743216
TUBB2B	DKFZP566F223 \|FLJ98847 \|MGC8685 \|tubb-paralog \|BA506K6.1	微管蛋白，β2B	-	HPRD	14743216
TUBB6	HST1601 \|MGC132410 \|MGC4083 \|tubb-5	微管蛋白，β6	-	HPRD	14743216
TXN	DKFZp686B1993 \| MGC61975 \| TRX \| TRX1	thioredoxin	-	HPRD,BioGRID	7788295
UBE2K	DKFZp564C1216 \| DKFZp686J24237 \| E2-25K \| HIP2 \| HYPG \| LIG	泛素结合酶E2K（UBC1同源物，酵母）	-	HPRD	9535861
UNC5CL	MGC34763 \| ZUD	UNC-5同源性C（秀丽隐杆线虫）类似	-	HPRD,BioGRID	14769797

Section V. Pathway annotation

Pathway name	路径大小	# SZGR 2.0 genes in pathway	信息
kegg mapk信号通路	267	205	All SZGR 2.0 genes in this pathway
KEGG趋化因子信号传导途径	190	128	All SZGR 2.0 genes in this pathway
KEGG APOPTOSIS	88	62	All SZGR 2.0 genes in this pathway
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY	102	88	All SZGR 2.0 genes in this pathway
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY	62	47	All SZGR 2.0 genes in this pathway
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY	71	51	All SZGR 2.0 genes in this pathway
KEGG胞质DNA传感通道	56	44	All SZGR 2.0 genes in this pathway
KEGG T CELL RECEPTOR SIGNALING PATHWAY	108	89	All SZGR 2.0 genes in this pathway
KEGG B CELL RECEPTOR SIGNALING PATHWAY	75	56	All SZGR 2.0 genes in this pathway
KEGG NEUROTROPHIN SIGNALING PATHWAY	126	103	All SZGR 2.0 genes in this pathway
KEGG ADIPOCYTOKINE SIGNALING PATHWAY	67	57	All SZGR 2.0 genes in this pathway
KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION	68	44	All SZGR 2.0 genes in this pathway
KEGG LEISHMANIA INFECTION	72	56	All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER	328	259	All SZGR 2.0 genes in this pathway
KEGG PANCREATIC CANCER	70	56	All SZGR 2.0 genes in this pathway
KEGG前列腺癌	89	75	All SZGR 2.0 genes in this pathway
KEGG慢性髓细胞性白血病	73	59	All SZGR 2.0 genes in this pathway
Kegg急性髓样白血病	60	47	All SZGR 2.0 genes in this pathway
小细胞肺癌	84	67	All SZGR 2.0 genes in this pathway
BIOCARTA RELA PATHWAY	16	12	All SZGR 2.0 genes in this pathway
Biocarta Akt途径	22	16	All SZGR 2.0 genes in this pathway
BIOCARTA ATM PATHWAY	20	16	All SZGR 2.0 genes in this pathway
BIOCARTA RANKL PATHWAY	14	13	All SZGR 2.0 genes in this pathway
Biocarta CDMAC途径	16	15	All SZGR 2.0 genes in this pathway
Biocarta CD40途径	15	13	All SZGR 2.0 genes in this pathway
BIOCARTA CERAMIDE PATHWAY	22	16	All SZGR 2.0 genes in this pathway
BIOCARTA TID PATHWAY	19	15	All SZGR 2.0 genes in this pathway
BIOCARTA GCR PATHWAY	22	17	All SZGR 2.0 genes in this pathway
Biocarta CXCR4途径	24	22	All SZGR 2.0 genes in this pathway
Biocarta RNA途径	10	9	All SZGR 2.0 genes in this pathway
BIOCARTA EPONFKB PATHWAY	11	11	All SZGR 2.0 genes in this pathway
BIOCARTA FMLP PATHWAY	39	29	All SZGR 2.0 genes in this pathway
BIOCARTA FREE PATHWAY	10	7	All SZGR 2.0 genes in this pathway
BIOCARTA HIVNEF PATHWAY	58	43	All SZGR 2.0 genes in this pathway
BIOCARTA HCMV PATHWAY	17	16	All SZGR 2.0 genes in this pathway
BIOCARTA GSK3 PATHWAY	27	26	All SZGR 2.0 genes in this pathway
BIOCARTA DEATH PATHWAY	33	24	All SZGR 2.0 genes in this pathway
BIOCARTA RACCYCD PATHWAY	26	23	All SZGR 2.0 genes in this pathway
BIOCARTA KERATINOCYTE PATHWAY	46	38	All SZGR 2.0 genes in this pathway
BIOCARTA MAPK PATHWAY	87	68	All SZGR 2.0 genes in this pathway
Biocarta VIP途径	29	26	All SZGR 2.0 genes in this pathway
Biocarta NTHI途径	24	20	All SZGR 2.0 genes in this pathway
BIOCARTA NFKB PATHWAY	23	19	All SZGR 2.0 genes in this pathway
BIOCARTA RAS PATHWAY	23	20	All SZGR 2.0 genes in this pathway
Biocarta Cardiacegf途径	18	16	All SZGR 2.0 genes in this pathway
BIOCARTA IL1R PATHWAY	33	29	All SZGR 2.0 genes in this pathway
BIOCARTA TCR PATHWAY	49	37	All SZGR 2.0 genes in this pathway
BIOCARTA TALL1 PATHWAY	15	15	All SZGR 2.0 genes in this pathway
BIOCARTA 41BB PATHWAY	17	15	All SZGR 2.0 genes in this pathway
BIOCARTA STRESS PATHWAY	25	18	All SZGR 2.0 genes in this pathway
BIOCARTA TNFR2 PATHWAY	18	15	All SZGR 2.0 genes in this pathway
Biocarta收费途径	37	31	All SZGR 2.0 genes in this pathway
ST肿瘤坏死因子途径	29	20	All SZGR 2.0 genes in this pathway
ST ERK1 ERK2 MAPK PATHWAY	32	25	All SZGR 2.0 genes in this pathway
SIG CD40PATHWAYMAP	34	28	All SZGR 2.0 genes in this pathway
ST P38 MAPK PATHWAY	37	28	All SZGR 2.0 genes in this pathway
ST GAQ PATHWAY	28	22	All SZGR 2.0 genes in this pathway
ST GA13 PATHWAY	37	32	All SZGR 2.0 genes in this pathway
ST T CELL SIGNAL TRANSDUCTION	45	33	All SZGR 2.0 genes in this pathway
ST B CELL ANTIGEN RECEPTOR	40	32	All SZGR 2.0 genes in this pathway
ST FAS SIGNALING PATHWAY	65	54	All SZGR 2.0 genes in this pathway
PID FCER1 PATHWAY	62	43	All SZGR 2.0 genes in this pathway
PID BCR 5PATHWAY	65	50	All SZGR 2.0 genes in this pathway
PID LYSOPHOSPHOLIPID PATHWAY	66	53	All SZGR 2.0 genes in this pathway
pid nfkappab非典型途径	17	15	All SZGR 2.0 genes in this pathway
PID NFKAPPAB CANONICAL PATHWAY	23	20	All SZGR 2.0 genes in this pathway
PID CD40 PATHWAY	31	26	All SZGR 2.0 genes in this pathway
PID IL12 2PATHWAY	63	54	All SZGR 2.0 genes in this pathway
PID AVB3 OPN PATHWAY	31	29	All SZGR 2.0 genes in this pathway
PID血管生成素受体途径	50	41	All SZGR 2.0 genes in this pathway
PID HDAC CLASSI PATHWAY	66	50	All SZGR 2.0 genes in this pathway
PID端粒酶途径	68	48	All SZGR 2.0 genes in this pathway
PID IL1 PATHWAY	34	28	All SZGR 2.0 genes in this pathway
PID REG GR PATHWAY	82	60	All SZGR 2.0 genes in this pathway
PID TNF PATHWAY	46	33	All SZGR 2.0 genes in this pathway
PID IL2 PI3K PATHWAY	34	27	All SZGR 2.0 genes in this pathway
PID神经酰胺途径	48	37	All SZGR 2.0 genes in this pathway
PID AMB2 NEUTROPHILS PATHWAY	41	32	All SZGR 2.0 genes in this pathway
PID IL23 PATHWAY	37	30	All SZGR 2.0 genes in this pathway
PID HIV NEF PATHWAY	35	26	All SZGR 2.0 genes in this pathway
PID EPO PATHWAY	34	29	All SZGR 2.0 genes in this pathway
WATANABE RECTAL CANCER RADIOTHERAPY RESPONSIVE UP	108	67	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP	485	293	All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病	1382	904	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP	544	308	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP	431	237	All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS UP	214	155	All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN	209	122	All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN	1781	1082	All SZGR 2.0 genes in this pathway
NUNODA RESPONSE TO DASATINIB IMATINIB UP	29	20	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 XPCS DN	88	71	All SZGR 2.0 genes in this pathway
Gilmore Core NFKB途径	14	10	All SZGR 2.0 genes in this pathway
SCHEIDEREIT IKK TARGETS	18	15	All SZGR 2.0 genes in this pathway
LI LUNG CANCER	41	30	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN	855	609	All SZGR 2.0 genes in this pathway
dirmeier LMP1响应迟到	57	41	All SZGR 2.0 genes in this pathway
YAN ESCAPE FROM ANOIKIS	24	19	All SZGR 2.0 genes in this pathway
TSAI RESPONSE TO IONIZING RADIATION	149	101	All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN	584	395	All SZGR 2.0 genes in this pathway
Pujana ATM PCC网络	1442	892	All SZGR 2.0 genes in this pathway
SHIN B CELL LYMPHOMA CLUSTER 3	28	23	All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP	223	140	All SZGR 2.0 genes in this pathway
Mori前BI淋巴细胞DN	77	49	All SZGR 2.0 genes in this pathway
BYSTRYKH造血细胞和脑QTL Trans	185	114	All SZGR 2.0 genes in this pathway
SMITH TERT TARGETS UP	145	91	All SZGR 2.0 genes in this pathway
tarte浆细胞与B淋巴细胞DN	38	25	All SZGR 2.0 genes in this pathway
BYSTROEM CORRELATED WITH IL5 UP	51	30	All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS	882	572	All SZGR 2.0 genes in this pathway
MAGRANGEAS MULTIPLE MYELOMA IGLL VS IGLK UP	42	24	All SZGR 2.0 genes in this pathway
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN	85	67	All SZGR 2.0 genes in this pathway
NEMETH INFLAMMATORY RESPONSE LPS UP	88	64	All SZGR 2.0 genes in this pathway
亚伯拉罕ALPC与多发性骨髓瘤	26	22	All SZGR 2.0 genes in this pathway
皮肤上的theilgaard中性粒细胞	77	52	All SZGR 2.0 genes in this pathway
RADMACHER AML PROGNOSIS	78	52	All SZGR 2.0 genes in this pathway
Iyengar对脂肪细胞因子的反应	10	8	All SZGR 2.0 genes in this pathway
NATSUME RESPONSE TO INTERFERON BETA UP	71	49	All SZGR 2.0 genes in this pathway
WEIGEL OXIDATIVE STRESS RESPONSE	35	28	All SZGR 2.0 genes in this pathway
周TNF信号4小时	54	36	All SZGR 2.0 genes in this pathway
HARRIS HYPOXIA	81	64	All SZGR 2.0 genes in this pathway
PAL PRMT5 TARGETS UP	203	135	All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP	1691	1088	All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE DN	123	76	All SZGR 2.0 genes in this pathway
ZHU CMV ALL UP	120	89	All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV NHEK DN	318	220	All SZGR 2.0 genes in this pathway
ZHU CMV 24 HR UP	93	65	All SZGR 2.0 genes in this pathway
DAZARD UV RESPONSE CLUSTER G6	153	112	All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED	1229	713	All SZGR 2.0 genes in this pathway
尼古斯基在乳腺癌中过度连接	22	19	All SZGR 2.0 genes in this pathway
fosTER TOLERANT MACROPHAGE DN	409	268	All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN	354	216	All SZGR 2.0 genes in this pathway
GAURNIER PSMD4 TARGETS	73	55	All SZGR 2.0 genes in this pathway
WINTER HYPOXIA METAGENE	242	168	All SZGR 2.0 genes in this pathway
LINDSTEDT DENDRITIC CELL MATURATION B	53	36	All SZGR 2.0 genes in this pathway
Hinata NFKB靶向角质形成细胞	91	63	All SZGR 2.0 genes in this pathway
HINATA NFKB TARGETS FIBROBLAST UP	84	60	All SZGR 2.0 genes in this pathway
COLINA TARGETS OF 4EBP1 AND 4EBP2	356	214	All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION	368	247	All SZGR 2.0 genes in this pathway
WORSCHECH TUMOR EVASION AND TOLEROGENICITY UP	30	19	All SZGR 2.0 genes in this pathway
DANG BOUND BY MYC	1103	714	All SZGR 2.0 genes in this pathway
tian tnf通过NFKB信令	28	21	All SZGR 2.0 genes in this pathway
LI INDUCED T TO NATURAL KILLER UP	307	182	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN	1972	1213	All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3	824	528	All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE NOT VIA P38	337	236	All SZGR 2.0 genes in this pathway
ROESSLER LIVER CANCER METASTASIS UP	107	72	All SZGR 2.0 genes in this pathway
ZWANG CLASS 3 TRANSIENTLY INDUCED BY EGF	222	159	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	mirna seq
miRNA family	UTR开始	UTR结束	匹配方法	miRNA ID	mirna seq
miR-30-3p	562	568	1A	HSA-MIR-30A-3P	CUUUCAGUCGGAUGUUUGCAGC
miR-30-3p	562	568	1A	HSA-MIR-30E-3P	CUUUCAGUCGGAUGUUUACAGC
mir-323	480	486	m8	hsa-miR-323^brain	GCACAUUACACGGUCGACCUCU
mir-9	29	35	m8	hsa-miR-9^SZ	UCUUUGGUUAUCUAGCUGUAUGA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Clickhereto see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Clickhere查看与大脑相关的miRNA列表。

Gene Page:NFKB1