Gene Page:NFKBIA

Summary？
基因 4792
Symbol NFKBIA
Synonyms IKBA|MAD-3|NFKBI
Description NFKB inhibitor alpha
Reference MIM：164008|HGNC：HGNC：7797|Ensembl：ENSG00000100906|HPRD：01235|Vega：Otthumg00000140220
Gene type 蛋白质编码
Map location 14q13
Pascal p-value 0.001
Sherlock p-value 0.469
胎儿β -0.267
主持人 Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description 信息
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
Network Shortest path distance of core genes in the Human protein-protein interaction network Contribution to shortest path in PPI network: 0.1501

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position 主持人 Gene Entrez ID pvalue QVALUE TSS距离 EQTL类型
rs1346726 chr8 27335218 NFKBIA 4792 0.05 trans

第二节。转录组注释

一般基因表达（GTEX）

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
GO:0008139 核定位序列结合 IPI 1493333
GO：0031625 ubiquitin protein ligase binding IPI 9859996
GO:0051059 NF-kappab结合 IPI 7739562
GO:0042802 identical protein binding IPI 16951195
生物过程 去学期 证据 神经关键字 PubMed ID
去：0000060 蛋白质进口到核，易位 IEA -
去：0007253 cytoplasmic sequestering of NF-kappaB NAS -
GO:0006915 apoptosis TAS 10747850
GO:0042345 regulation of NF-kappaB import into nucleus NAS 3140380
GO:0042127 regulation of cell proliferation IEA -
GO:0032496 对脂多糖的反应 IEA -
GO：0031663 lipopolysaccharide-mediated signaling pathway IEA -
GO:0043392 DNA结合的负调控 NAS 3140380
GO:0043330 response to exogenous dsRNA IEA -
GO：0032495 response to muramyl dipeptide IEA -
GO:0045638 negative regulation of myeloid cell differentiation IEA -
GO:0045746 negative regulation of Notch signaling pathway IEA -
GO:0044419 interspecies interaction between organisms IEA -
Cellular component 去学期 证据 神经关键字 PubMed ID
GO:0005829 cytosol EXP 10723127
GO:0005829 cytosol IEA -
GO:0005634 nucleus 艾达 7679069
去：0005737 cytoplasm 艾达 3140380

Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B 实验 Source PubMed ID
ARRB1 ARB1 |arr1 arrestin, beta 1 Beta-arr1与I-Kappa-B-Alpha相互作用，以防止I-Kappa-B-Alpha的磷酸化和降解。 BIND 15125834
ARRB2 ARB2 | ARR2 | BARR2 | DKFZp686L0365 arrestin, beta 2 The amino terminus of Beta-Arr2 interacts with the carboxy terminus of I-kappa-B-alpha to prevent I-kappa-B-alpha phosphorylation and degradation. BIND 15125834
BARD1 - BRCA1 associated RING domain 1 Two-hybrid Biogrid 10362352
BTRC beta-trcp |fbw1a |fbxw1 |fbxw1a |FWD1 |MGC4643 |BTRCP |BTRCP1 |betatrcp beta-transducin repeat containing - HPRD,BioGRID 9990853
BTRC beta-trcp |fbw1a |fbxw1 |fbxw1a |FWD1 |MGC4643 |BTRCP |BTRCP1 |betatrcp beta-transducin repeat containing H-BETA-TRCP与磷酸化的I-Kappa-B-Alpha相互作用并促进泛素化。这种相互作用是基于未指定物种的人β-TRCP（H-Beta-TRCP）和I-Kappa-B-Alpha之间的相互作用进行建模的。 BIND 9990853
CAPN1 CANP | CANP1 | CANPL1 | muCANP | muCL 钙蛋白酶1，（mu/i）大亚基 - HPRD,BioGRID 10521480
CHUK IKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16 保守的螺旋环螺旋无处不在激酶 生化活动
重构的复合物		 Biogrid 9252186|9751059
CHUK IKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16 保守的螺旋环螺旋无处不在激酶 ikk-alpha磷酸化I-kappa-b-alpha。 BIND 9346485
CHUK IKBKA | IKK-alpha | IKK1 | IKKA | NFKBIKA | TCF16 保守的螺旋环螺旋无处不在激酶 ikk-alpha磷酸化I-kappa-b-alpha。这种相互作用是基于未指定物种的人类IKK-Alpha和I-Kappa-B-Alpha之间的相互作用进行建模的。 BIND 15782119
COMMD1 C2orf5 |MGC27155 |Murr1 包含1的铜代谢（MURR1）结构域 亲和力捕获 - 韦斯特恩 Biogrid 14685242
COMMD1 C2orf5 |MGC27155 |Murr1 包含1的铜代谢（MURR1）结构域 Murr1 interacts with I-kappaB-alpha BIND 14685242
dynll1 DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1 dynein, light chain, LC8-type 1 - HPRD,BioGRID 9372968
dynll1 DLC1 | DLC8 | DNCL1 | DNCLC1 | LC8 | LC8a | MGC126137 | MGC126138 | PIN | hdlc1 dynein, light chain, LC8-type 1 I-Kappa-B-Alpha与DLC-1相互作用。 BIND 9372968
ELP3 FLJ10422 | KAT9 伸长protein 3 homolog (S. cerevisiae) - HPRD 14743216
ERC1 Cast2 | ELKS | KIAA1081 | MGC12974 | RAB6IP2 ELKS/RAB6-interacting/CAST family member 1 麋鹿与i-kappa-b-alpha互动。 BIND 15218148
FBXW11 BTRC2 | BTRCP2 | FBW1B | FBXW1B | Fbw11 | Hos | KIAA0696 F-box和WD重复域包含11 - HPRD,BioGRID 10644755
G3BP2 - GTPase activating protein (SH3 domain) binding protein 2 - HPRD,BioGRID 10969074
HDAC1 DKFZP686H12203 |gon-10 |HD1 |RPD3 |RPD3L1 histone deacetylase 1 HDAC1 interacts with I-kappa-B-alpha. BIND 12972430
HDAC3 HD3 | RPD3 | RPD3-2 histone deacetylase 3 HDAC3与I-Kappa-B-Alpha相互作用。 BIND 12972430
HNRNPA1 HNRPA1 | MGC102835 heterogeneous nuclear ribonucleoprotein A1 亲和力捕获 - 韦斯特恩
重构的复合物		 Biogrid 11313474
hnrnpab ABBP1 | FLJ40338 | HNRPAB heterogeneous nuclear ribonucleoprotein A/B - HPRD 11313474
HOXB7 HHO.C1 | HOX2 | HOX2C | Hox-2.3 homeobox B7 - HPRD,BioGRID 10026139
HSPA8 HSC54 | HSC70 | HSC71 | HSP71 | HSP73 | HSPA10 | LAP1 | MGC131511 | MGC29929 | NIP71 heat shock 70kDa protein 8 - HPRD 14743216
IKBKAP DKFZp781H1425 | DYS | ELP1 | FD | FLJ12497 | IKAP | IKI3 | TOT1 B细胞中Kappa光多肽基因增强子的抑制剂，激酶复合物相关蛋白 重构的复合物 Biogrid 9751059
ikbkb FLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta Ikk-beta与I-Kappa-B-Alpha相互作用并磷酸化。 BIND 9346485
ikbkb FLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta Ikk-beta与I-Kappa-B-Alpha相互作用并磷酸化。这种相互作用是基于未指定物种的Ikk-beta和I-kappa-b-alpha之间的相互作用进行建模的。 BIND 15808510
ikbkb FLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 重构的复合物 Biogrid 9751059|9891086
ikbkb FLJ40509 | IKK-beta | IKK2 | IKKB | MGC131801 | NFKBIKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta IKK-beta phosphorylates I-kappa-Ba. This interaction was modelled on a demonstrated interaction between IKK-beta from unknown species and I-kappa-Ba from unknown species. BIND 15084260
LCK yt16 |p56lck |pp58lck lymphocyte-specific protein tyrosine kinase LCK interacts with and phosphorylates NFKBIA (I-kappa-B-alpha). This interaction was modeled on a demonstrated interaction between LCK from an unspecified species and human NFKBIA. BIND 14534291
MAP3K14 FTDCR1B | HS | HSNIK | NIK mitogen-activated protein kinase kinase kinase 14 重构的复合物 Biogrid 9751059
MCM7 CDABP0042 | CDC47 | MCM2 | P1.1-MCM3 | P1CDC47 | P85MCM | PNAS-146 微型鲜体维护复杂组件7 - HPRD 14743216
Med19 DT2P1G7 |LCMR1 mediator complex subunit 19 Two-hybrid Biogrid 16169070
NCOR2 CTG26 | SMRT | SMRTE | SMRTE-tau | TNRC14 | TRAC-1 | TRAC1 核受体共抑制剂2 亲和力捕获 - 韦斯特恩 Biogrid 12589049
NFKB1 DKFZP686C01211 |EBP-1 |kbf1 |MGC54151 |nf-kappa-b |NFKB-P105 |NFKB-P50 |P105 B细胞中Kappa光多肽基因增强子的核因子1 - HPRD,BioGRID 9738011
NFKB1 DKFZP686C01211 |EBP-1 |kbf1 |MGC54151 |nf-kappa-b |NFKB-P105 |NFKB-P50 |P105 B细胞中Kappa光多肽基因增强子的核因子1 p50 associates with I-kappa-B-alpha. BIND 9135156
PIK3R1 GRB1 | p85 | p85-ALPHA 磷酸肌醇3-激酶，调节亚基1（alpha） - HPRD,BioGRID 9892650
PIR - pirin (iron-binding nuclear protein) Two-hybrid Biogrid 10362352
POM121 DKFZp586G1822 | DKFZp586P2220 | FLJ41820 | KIAA0618 | MGC3792 | POM121A POM121 membrane glycoprotein (rat) Two-hybrid Biogrid 16189514
PTPN13 DKFZP686J1497 |FAP-1 |PNP1 |PTP-BAS |ptp-bl |ptp1e |ptpl1 |ptple protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) - HPRD,BioGRID 9882613
REL C-Rel V-REL网状内皮症病毒性癌基因同源物（Avian） 亲和力捕获 - 韦斯特恩 Biogrid 10706725
RELA MGC131774 | NFKB3 | p65 v-rel reticuloendotheliosis viral oncogene homolog A (avian) 亲和力捕获 - 韦斯特恩
重构的复合物		 Biogrid 8139561|9738011
|9751059|9990853
|11313474|11533489
|12419806
RELA MGC131774 | NFKB3 | p65 v-rel reticuloendotheliosis viral oncogene homolog A (avian) I-kappa-B-alpha interacts with NF-kappa-B-p65. BIND 15125834
RELA MGC131774 | NFKB3 | p65 v-rel reticuloendotheliosis viral oncogene homolog A (avian) RelA, the p65 subunit of the NF-kappaB complex, interacts with I-kappaB-alpha BIND 14685242
RPS27L - ribosomal protein S27-like - HPRD 14743216
RPS6KA1 HU-1 | MAPKAPK1A | RSK | RSK1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 - HPRD,BioGRID 9214631
SUMO4 IDDM5 | SMT3H4 | SUMO-4 | dJ281H8.4 SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae) - HPRD,BioGRID 15247916
TIMM50 MGC102733 | TIM50 | TIM50L translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) - HPRD 14743216
TNFSF11 CD254 |ODF |OPGL |OPTB2 |rankl |tr |hrankl2 |SODF tumor necrosis factor (ligand) superfamily, member 11 - HPRD 10635328
TP53 FLJ92943 | LFS1 | TRP53 | p53 tumor protein p53 - HPRD,BioGRID 11799106
tuba1b K-Alpha-1 tubulin, alpha 1b - HPRD 9372968
tuba3c TUBA2 | bA408E5.3 tubulin, alpha 3c - HPRD 9372968
ube2e3 ubch9 |UBCM2 ubiquitin-conjugating酶E2E 3 (UBC4/5同族体, yeast) - HPRD,BioGRID 9409737
VCP IBMPFD | MGC131997 | MGC148092 | MGC8560 | TERA | p97 valosin-containing protein - HPRD,BioGRID 9452483


Section V. Pathway annotation

Pathway name 路径大小 # SZGR 2.0 genes in pathway 信息
KEGG趋化因子信号传导途径 190 128 All SZGR 2.0 genes in this pathway
KEGG APOPTOSIS 88 62 All SZGR 2.0 genes in this pathway
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY 102 88 All SZGR 2.0 genes in this pathway
KEGG NOD LIKE RECEPTOR SIGNALING PATHWAY 62 47 All SZGR 2.0 genes in this pathway
KEGG RIG I LIKE RECEPTOR SIGNALING PATHWAY 71 51 All SZGR 2.0 genes in this pathway
kegg胞质DNA感应途径 56 44 All SZGR 2.0 genes in this pathway
KEGG T CELL RECEPTOR SIGNALING PATHWAY 108 89 All SZGR 2.0 genes in this pathway
KEGG B CELL RECEPTOR SIGNALING PATHWAY 75 56 All SZGR 2.0 genes in this pathway
KEGG NEUROTROPHIN SIGNALING PATHWAY 126 103 All SZGR 2.0 genes in this pathway
KEGG ADIPOCYTOKINE SIGNALING PATHWAY 67 57 All SZGR 2.0 genes in this pathway
KEGG EPITHELIAL CELL SIGNALING IN HELICOBACTER PYLORI INFECTION 68 44 All SZGR 2.0 genes in this pathway
KEGG LEISHMANIA INFECTION 72 56 All SZGR 2.0 genes in this pathway
KEGG PATHWAYS IN CANCER 328 259 All SZGR 2.0 genes in this pathway
KEGG前列腺癌 89 75 All SZGR 2.0 genes in this pathway
KEGG慢性髓细胞性白血病 73 59 All SZGR 2.0 genes in this pathway
小细胞肺癌 84 67 All SZGR 2.0 genes in this pathway
BIOCARTA RELA PATHWAY 16 12 All SZGR 2.0 genes in this pathway
Biocarta Akt途径 22 16 All SZGR 2.0 genes in this pathway
BIOCARTA ATM PATHWAY 20 16 All SZGR 2.0 genes in this pathway
Biocarta CDMAC途径 16 15 All SZGR 2.0 genes in this pathway
Biocarta CD40途径 15 13 All SZGR 2.0 genes in this pathway
BIOCARTA TID PATHWAY 19 15 All SZGR 2.0 genes in this pathway
Biocarta RNA途径 10 9 All SZGR 2.0 genes in this pathway
BIOCARTA EPONFKB PATHWAY 11 11 All SZGR 2.0 genes in this pathway
BIOCARTA FMLP PATHWAY 39 29 All SZGR 2.0 genes in this pathway
BIOCARTA HIVNEF PATHWAY 58 43 All SZGR 2.0 genes in this pathway
BIOCARTA DEATH PATHWAY 33 24 All SZGR 2.0 genes in this pathway
BIOCARTA RACCYCD PATHWAY 26 23 All SZGR 2.0 genes in this pathway
BIOCARTA KERATINOCYTE PATHWAY 46 38 All SZGR 2.0 genes in this pathway
BIOCARTA MAPK PATHWAY 87 68 All SZGR 2.0 genes in this pathway
BIOCARTA PPARA PATHWAY 58 43 All SZGR 2.0 genes in this pathway
Biocarta VIP途径 29 26 All SZGR 2.0 genes in this pathway
Biocarta NTHI途径 24 20 All SZGR 2.0 genes in this pathway
BIOCARTA NFKB PATHWAY 23 19 All SZGR 2.0 genes in this pathway
BIOCARTA IL1R PATHWAY 33 29 All SZGR 2.0 genes in this pathway
BIOCARTA TCR PATHWAY 49 37 All SZGR 2.0 genes in this pathway
BIOCARTA 41BB PATHWAY 17 15 All SZGR 2.0 genes in this pathway
BIOCARTA STRESS PATHWAY 25 18 All SZGR 2.0 genes in this pathway
BIOCARTA TNFR2 PATHWAY 18 15 All SZGR 2.0 genes in this pathway
Biocarta收费途径 37 31 All SZGR 2.0 genes in this pathway
ST肿瘤坏死因子途径 29 20 All SZGR 2.0 genes in this pathway
SIG CD40PATHWAYMAP 34 28 All SZGR 2.0 genes in this pathway
ST GAQ PATHWAY 28 22 All SZGR 2.0 genes in this pathway
ST GA13 PATHWAY 37 32 All SZGR 2.0 genes in this pathway
ST T CELL SIGNAL TRANSDUCTION 45 33 All SZGR 2.0 genes in this pathway
ST B CELL ANTIGEN RECEPTOR 40 32 All SZGR 2.0 genes in this pathway
ST FAS SIGNALING PATHWAY 65 54 All SZGR 2.0 genes in this pathway
PID BCR 5PATHWAY 65 50 All SZGR 2.0 genes in this pathway
PID LYSOPHOSPHOLIPID PATHWAY 66 53 All SZGR 2.0 genes in this pathway
pid nfkappab非典型途径 17 15 All SZGR 2.0 genes in this pathway
PID NFKAPPAB CANONICAL PATHWAY 23 20 All SZGR 2.0 genes in this pathway
PID CD40 PATHWAY 31 26 All SZGR 2.0 genes in this pathway
PID AVB3 OPN PATHWAY 31 29 All SZGR 2.0 genes in this pathway
PID HDAC CLASSI PATHWAY 66 50 All SZGR 2.0 genes in this pathway
PID神经酰胺途径 48 37 All SZGR 2.0 genes in this pathway
PID IL23 PATHWAY 37 30 All SZGR 2.0 genes in this pathway
PID HIV NEF PATHWAY 35 26 All SZGR 2.0 genes in this pathway
PID AURORA A PATHWAY 31 20 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING BY NGF 217 167 All SZGR 2.0 genes in this pathway
REACTOME TRIF MEDIATED TLR3 SIGNALING 74 54 All SZGR 2.0 genes in this pathway
REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI 18 15 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR 97 66 All SZGR 2.0 genes in this pathway
REACTOME ACTIVATION OF NF KAPPAB IN B CELLS 64 43 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 126 90 All SZGR 2.0 genes in this pathway
Reactome TCR信号传导 54 46 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM TCR SIGNALING 37 32 All SZGR 2.0 genes in this pathway
REACTOME P75NTR SIGNALS VIA NFKB 14 10 All SZGR 2.0 genes in this pathway
REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL 11 8 All SZGR 2.0 genes in this pathway
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 81 61 All SZGR 2.0 genes in this pathway
REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX 23 17 All SZGR 2.0 genes in this pathway
REACTOME TRAF6 MEDIATED NFKB ACTIVATION 21 17 All SZGR 2.0 genes in this pathway
NFKB REACTOME TRAF6介导的诱导和地图KINASES UPON TLR7 8 OR 9 ACTIVATION 77 57 All SZGR 2.0 genes in this pathway
REACTOME NFKB AND MAP KINASES ACTIVATION MEDIATED BY TLR4 SIGNALING REPERTOIRE 72 53 All SZGR 2.0 genes in this pathway
REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS 73 57 All SZGR 2.0 genes in this pathway
REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE 83 63 All SZGR 2.0 genes in this pathway
REACTOME INNATE IMMUNE SYSTEM 279 178 All SZGR 2.0 genes in this pathway
REACTOME ACTIVATED TLR4 SIGNALLING 93 69 All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933 616 All SZGR 2.0 genes in this pathway
Reactome收费受体级联 118 84 All SZGR 2.0 genes in this pathway
Reactome适应性免疫系统 539 350 All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA UP 294 178 All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS UP 473 314 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LIVE UP 485 293 All SZGR 2.0 genes in this pathway
Casorelli急性临时细胞白血病 177 110 All SZGR 2.0 genes in this pathway
Basaki YBX1靶向 290 177 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP 233 161 All SZGR 2.0 genes in this pathway
SENESE HDAC1 TARGETS UP 457 269 All SZGR 2.0 genes in this pathway
SENESE HDAC3 TARGETS UP 501 327 All SZGR 2.0 genes in this pathway
Hummel Burkitts淋巴瘤DN 15 10 All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP 544 308 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS UP 214 155 All SZGR 2.0 genes in this pathway
甲状腺癌的Rodrigues分化不佳的DN 805 505 All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 48HR UP 128 95 All SZGR 2.0 genes in this pathway
KOKKINAKIS METHIONINE DEPRIVATION 96HR DN 75 50 All SZGR 2.0 genes in this pathway
lau凋亡CDKN2A UP 55 40 All SZGR 2.0 genes in this pathway
CHIARADONNA NEOPLASTIC TRANSFORMATION KRAS UP 126 72 All SZGR 2.0 genes in this pathway
berenjeno由Rhoa Up Troment 536 340 All SZGR 2.0 genes in this pathway
NUNODA RESPONSE TO DASATINIB IMATINIB UP 29 20 All SZGR 2.0 genes in this pathway
Olsson E2F3靶向DN 49 33 All SZGR 2.0 genes in this pathway
Gilmore Core NFKB途径 14 10 All SZGR 2.0 genes in this pathway
SCHEIDEREIT IKK TARGETS 18 15 All SZGR 2.0 genes in this pathway
RASHI RESPONSE TO IONIZING RADIATION 2 127 92 All SZGR 2.0 genes in this pathway
RASHI NFKB1 TARGETS 19 18 All SZGR 2.0 genes in this pathway
MARTIN INTERACT WITH HDAC 44 31 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 2B 392 251 All SZGR 2.0 genes in this pathway
DIRMEIER LMP1 RESPONSE EARLY 66 48 All SZGR 2.0 genes in this pathway
TSAI RESPONSE TO IONIZING RADIATION 149 101 All SZGR 2.0 genes in this pathway
Pujana乳腺癌点燃int网络 101 73 All SZGR 2.0 genes in this pathway
通过ELK3 DN的缺氧总缺氧 156 106 All SZGR 2.0 genes in this pathway
通过HIF1A DN的缺氧总缺氧 110 78 All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 AND HIF1A UP 142 104 All SZGR 2.0 genes in this pathway
Nuytten EZH2靶向 1037 673 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 All SZGR 2.0 genes in this pathway
洛佩兹MBD目标 957 597 All SZGR 2.0 genes in this pathway
LOCKWOOD AMPLIFIED IN LUNG CANCER 214 139 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487 286 All SZGR 2.0 genes in this pathway
Koyama Sema3b靶向DN 411 249 All SZGR 2.0 genes in this pathway
gotzmann上皮到间充质过渡dn 206 136 All SZGR 2.0 genes in this pathway
SHIN B CELL LYMPHOMA CLUSTER 8 36 28 All SZGR 2.0 genes in this pathway
ZHANG RESPONSE TO IKK INHIBITOR AND TNF UP 223 140 All SZGR 2.0 genes in this pathway
ZUCCHI METASTASIS DN 44 29 All SZGR 2.0 genes in this pathway
TARTE PLASMA CELL VS PLASMABLAST UP 398 262 All SZGR 2.0 genes in this pathway
YAGI AML RELAPSE PROGNOSIS 35 24 All SZGR 2.0 genes in this pathway
Golub所有vs AML DN 24 14 All SZGR 2.0 genes in this pathway
sana tnf发出信号 83 56 All SZGR 2.0 genes in this pathway
GALINDO IMMUNE RESPONSE TO ENTEROTOXIN 85 67 All SZGR 2.0 genes in this pathway
NEMETH INFLAMMATORY RESPONSE LPS UP 88 64 All SZGR 2.0 genes in this pathway
LENAOUR DENDRITIC CELL MATURATION DN 128 90 All SZGR 2.0 genes in this pathway
VERHAAK AML WITH NPM1 MUTATED UP 183 111 All SZGR 2.0 genes in this pathway
YAGI AML SURVIVAL 129 87 All SZGR 2.0 genes in this pathway
IGLESIAS E2F TARGETS UP 151 103 All SZGR 2.0 genes in this pathway
MUNSHI MULTIPLE MYELOMA UP 81 52 All SZGR 2.0 genes in this pathway
BASSO CD40 SIGNALING UP 101 76 All SZGR 2.0 genes in this pathway
DEBIASI APOPTOSIS BY REOVIRUS INFECTION UP 314 201 All SZGR 2.0 genes in this pathway
LEE CALORIE RESTRICTION NEOCORTEX UP 83 66 All SZGR 2.0 genes in this pathway
HU基因毒素作用直接与间接4小时 37 22 All SZGR 2.0 genes in this pathway
周TNF信号4小时 54 36 All SZGR 2.0 genes in this pathway
麦克道尔急性肺损伤 45 29 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
卫星对干扰素βdn的响应 52 33 All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS STEM CELL 254 164 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
CHEN LVAD SUPPORT OF FAILING HEART UP 103 69 All SZGR 2.0 genes in this pathway
大脑衰老 262 186 All SZGR 2.0 genes in this pathway
ZHU CMV ALL UP 120 89 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 18HR UP 178 111 All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C0 107 72 All SZGR 2.0 genes in this pathway
周TNF信号30分钟 54 36 All SZGR 2.0 genes in this pathway
GEISS RESPONSE TO DSRNA UP 38 29 All SZGR 2.0 genes in this pathway
ZHU CMV 24 HR UP 93 65 All SZGR 2.0 genes in this pathway
江缺氧正常 311 205 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 24HR UP 148 96 All SZGR 2.0 genes in this pathway
HILLION HMGA1 TARGETS 90 71 All SZGR 2.0 genes in this pathway
HILLION HMGA1B TARGETS 92 68 All SZGR 2.0 genes in this pathway
SARRIO EPITHELIAL MESENCHYMAL TRANSITION DN 154 101 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER CANCER DN 540 340 All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN UP 439 257 All SZGR 2.0 genes in this pathway
BOQUEST STEM CELL CULTURED VS FRESH UP 425 298 All SZGR 2.0 genes in this pathway
CHEN HOXA5 TARGETS 9HR UP 223 132 All SZGR 2.0 genes in this pathway
QI PLASMACYTOMA UP 259 185 All SZGR 2.0 genes in this pathway
BLUM RESPONSE TO SALIRASIB UP 245 159 All SZGR 2.0 genes in this pathway
WANG TUMOR INVASIVENESS UP 374 247 All SZGR 2.0 genes in this pathway
VILIMAS NOTCH1 TARGETS UP 52 41 All SZGR 2.0 genes in this pathway
SEKI INFLAMMATORY RESPONSE LPS UP 77 56 All SZGR 2.0 genes in this pathway
ICHIBA GRAFT VERSUS HOST DISEASE D7 UP 107 67 All SZGR 2.0 genes in this pathway
LINDSTEDT DENDRITIC CELL MATURATION B 53 36 All SZGR 2.0 genes in this pathway
马歇尔病毒感染反应dn 29 21 All SZGR 2.0 genes in this pathway
SWEET LUNG CANCER KRAS DN 435 289 All SZGR 2.0 genes in this pathway
Hinata NFKB靶向角质形成细胞 91 63 All SZGR 2.0 genes in this pathway
HINATA NFKB TARGETS FIBROBLAST UP 84 60 All SZGR 2.0 genes in this pathway
SHEDDEN LUNG CANCER GOOD SURVIVAL A4 196 124 All SZGR 2.0 genes in this pathway
Hsiao家政基因 389 245 All SZGR 2.0 genes in this pathway
CROONQUIST STROMAL STIMULATION UP 60 42 All SZGR 2.0 genes in this pathway
CROONQUIST NRAS VS STROMAL STIMULATION DN 99 65 All SZGR 2.0 genes in this pathway
COULOUARN TEMPORAL TGFB1 SIGNATURE DN 138 99 All SZGR 2.0 genes in this pathway
Schoen NFKB信号 34 26 All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SUBCLASS S3 266 180 All SZGR 2.0 genes in this pathway
开罗肝母细胞瘤课程DN 210 141 All SZGR 2.0 genes in this pathway
DORN腺病毒感染12小时DN 33 25 All SZGR 2.0 genes in this pathway
DORN ADENOVIRUS INFECTION 24HR DN 43 32 All SZGR 2.0 genes in this pathway
DORN ADENOVIRUS INFECTION 32HR DN 39 28 All SZGR 2.0 genes in this pathway
DORN ADENOVIRUS INFECTION 48HR DN 40 29 All SZGR 2.0 genes in this pathway
tian tnf通过NFKB信令 28 21 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway
YAO TEMPORAL RESPONSE TO PROGESTERONE CLUSTER 3 15 7 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 2HR UP 39 30 All SZGR 2.0 genes in this pathway
Johnstone Parvb目标3 430 288 All SZGR 2.0 genes in this pathway
WANG TNF TARGETS 24 17 All SZGR 2.0 genes in this pathway
KASLER HDAC7 TARGETS 2 DN 32 23 All SZGR 2.0 genes in this pathway
Krieg缺氧不是通过KDM3A 770 480 All SZGR 2.0 genes in this pathway
PHONG TNF TARGETS UP 63 43 All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE NOT VIA P38 337 236 All SZGR 2.0 genes in this pathway
Altemeier对LPS具有机械通气的反应 128 81 All SZGR 2.0 genes in this pathway
Zwang仅通过第一egf脉冲瞬时向上 1839 928 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
miR-381 27 34 1A,m8 HSA-MIR-381 UAUACAAGGGCAAGCUCUCUGU
miR-493-5p 37 43 1A HSA-MIR-493-5p UUGUACAUGGUAGGCUUUCAUU