Gene Page:NFX1
Summary?
| GeneID | 4799 |
| Symbol | NFX1 |
| Synonyms | NFX2|TEG-42|Tex42 |
| Description | nuclear transcription factor, X-box binding 1 |
| Reference | MIM: 603255|HGNC:HGNC:7803|Ensembl:ENSG00000086102|HPRD:11936|Vega:OTTHUMG00000019772 |
| Gene type | protein-coding |
| Map location | 9p13.3 |
| Pascal p-value | 0.004 |
| Sherlock p-value | 0.534 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| NME1-NME2 | 0.89 | 0.93 |
| C1QBP | 0.87 | 0.89 |
| CLTA | 0.86 | 0.89 |
| PSMD13 | 0.86 | 0.86 |
| MYL12B | 0.86 | 0.88 |
| DCTN3 | 0.85 | 0.85 |
| PSMA7 | 0.85 | 0.88 |
| COPS6 | 0.85 | 0.87 |
| PSMB3 | 0.84 | 0.87 |
| PSMB5 | 0.84 | 0.88 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.26 | -0.64 | -0.64 |
| AF347015.2 | -0.63 | -0.62 |
| AF347015.15 | -0.61 | -0.60 |
| MT-CYB | -0.61 | -0.60 |
| AF347015.8 | -0.61 | -0.58 |
| AF347015.33 | -0.60 | -0.61 |
| MT-CO2 | -0.59 | -0.55 |
| AF347015.18 | -0.58 | -0.61 |
| AF347015.9 | -0.57 | -0.60 |
| AF347015.27 | -0.56 | -0.58 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 140 | 77 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | 54 | 34 | All SZGR 2.0 genes in this pathway |
| REACTOME RNA POL II TRANSCRIPTION | 105 | 54 | All SZGR 2.0 genes in this pathway |
| REACTOME MRNA PROCESSING | 161 | 86 | All SZGR 2.0 genes in this pathway |
| REACTOME MRNA SPLICING | 111 | 58 | All SZGR 2.0 genes in this pathway |
| REACTOME TRANSCRIPTION | 210 | 127 | All SZGR 2.0 genes in this pathway |
| REACTOME MRNA 3 END PROCESSING | 35 | 18 | All SZGR 2.0 genes in this pathway |
| REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION | 44 | 22 | All SZGR 2.0 genes in this pathway |
| PARENT MTOR SIGNALING UP | 567 | 375 | All SZGR 2.0 genes in this pathway |
| DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA DN | 320 | 184 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| ENK UV RESPONSE EPIDERMIS UP | 293 | 179 | All SZGR 2.0 genes in this pathway |
| GAUSSMANN MLL AF4 FUSION TARGETS G UP | 238 | 135 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO BEXAROTENE UP | 34 | 17 | All SZGR 2.0 genes in this pathway |
| PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | All SZGR 2.0 genes in this pathway |
| PUJANA ATM PCC NETWORK | 1442 | 892 | All SZGR 2.0 genes in this pathway |
| SMITH TERT TARGETS UP | 145 | 91 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 2 DN | 336 | 211 | All SZGR 2.0 genes in this pathway |
| KOINUMA TARGETS OF SMAD2 OR SMAD3 | 824 | 528 | All SZGR 2.0 genes in this pathway |