Gene Page:CRIM1

Summary？
基因 51232
象征 CRIM1
Synonyms Crim-1 | S52
Description 富含半胱氨酸的跨膜BMP调节剂1（类似于Chordin）
Reference MIM：606189|HGNC:HGNC:2359|Ensembl：ENSG00000150938|HPRD：08392|Vega：Otthumg0000000099419
基因类型 蛋白质编码
Map location 2P21
Pascal p-value 0.024
主持人 Cerebellar Hemisphere

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp 全基因组协会研究 GWAS
go_annotation 将与神经相关的关键字映射到基因本体论注释 与神经相关的关键字的命中：1

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达（GTEX）

不可用

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去：0005010 胰岛素样生长因子受体活性 TAS 10642437
GO:0004867 丝氨酸型内肽酶抑制剂活性 国际能源机构 -
去：0005520 insulin-like growth factor binding 国际能源机构 -
GO:0004857 enzyme inhibitor activity 国际能源机构 -
去：0004197 半胱氨酸型内肽酶活性 国际能源机构 -
生物过程 去学期 证据 神经关键字 PubMed ID
GO:0007399 nervous system development TAS 神经突（GO期限：5） 10642437
GO:0001558 细胞生长调节 国际能源机构 -
去：0006508 蛋白水解作用 国际能源机构 -
Cellular component 去学期 证据 神经关键字 PubMed ID
去：0005576 细胞外区域 国际能源机构 -
GO：0016021 膜不可或缺 TAS 10642437
去：0005886 plasma membrane 国际能源机构 -

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
中村肿瘤区周围与中央 285 181 All SZGR 2.0 genes in this pathway
刘前列腺癌DN 481 290 All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS UP 579 346 All SZGR 2.0 genes in this pathway
LIU CMYB TARGETS UP 165 106 All SZGR 2.0 genes in this pathway
刘vmyb的目标 127 78 All SZGR 2.0 genes in this pathway
乳腺癌腔与间充质DN 460 312 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 6HR UP 85 54 All SZGR 2.0 genes in this pathway
PAPASPYRIDONOS UNSTABLE ATEROSCLEROTIC PLAQUE DN 43 29 All SZGR 2.0 genes in this pathway
Senese HDAC3靶向DN 536 332 All SZGR 2.0 genes in this pathway
Tien肠益生菌2小时DN 88 53 All SZGR 2.0 genes in this pathway
Tien肠益生菌6小时DN 167 100 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN 209 122 All SZGR 2.0 genes in this pathway
Jaatinen造血干细胞向上 316 190 All SZGR 2.0 genes in this pathway
Wamunyokoli卵巢癌LMP DN 199 124 All SZGR 2.0 genes in this pathway
hahtola兄弟姐妹Fungoides皮肤 177 113 All SZGR 2.0 genes in this pathway
ENK UV响应角质形成细胞DN 485 334 All SZGR 2.0 genes in this pathway
McBryan Pubertal乳房5 6WK DN 137 97 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK UP 197 135 All SZGR 2.0 genes in this pathway
McBryan Pubertal TGFB1靶向 169 127 All SZGR 2.0 genes in this pathway
Mahadevan伊马替尼抵抗 23 15 All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE DN 712 443 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3公共DN 483 336 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS DN 1024 594 All SZGR 2.0 genes in this pathway
Buytaert光动力疗法应力DN 637 377 All SZGR 2.0 genes in this pathway
洛佩兹MBD目标 957 597 All SZGR 2.0 genes in this pathway
Schaeffer前列腺开发6小时DN 514 330 All SZGR 2.0 genes in this pathway
Benporath SOX2目标 734 436 All SZGR 2.0 genes in this pathway
Petretto心脏肥大 34 26 All SZGR 2.0 genes in this pathway
林被肿瘤微环境沉默 108 73 All SZGR 2.0 genes in this pathway
MATSUDA NATURAL KILLER DIFFERENTIATION 475 313 All SZGR 2.0 genes in this pathway
LEI MYB目标 318 215 All SZGR 2.0 genes in this pathway
Roeth Tert目标DN 8 7 All SZGR 2.0 genes in this pathway
HADDAD B淋巴细胞祖细胞 293 193 All SZGR 2.0 genes in this pathway
Li Wilms肿瘤与胎儿肾脏1 182 119 All SZGR 2.0 genes in this pathway
伊万诺娃造血干细胞长期 302 191 All SZGR 2.0 genes in this pathway
阿尔茨海默氏病dn 1237 837 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
Browne HCMV感染24小时DN 148 102 All SZGR 2.0 genes in this pathway
KANG DOXORUBICIN RESISTANCE DN 19 8 All SZGR 2.0 genes in this pathway
贝尔德糖尿病性肾病DN 434 302 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720 440 All SZGR 2.0 genes in this pathway
coates巨噬细胞M1 vs M2向上 81 52 All SZGR 2.0 genes in this pathway
马丁内斯RB1靶向 673 430 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593 372 All SZGR 2.0 genes in this pathway
Martinez RB1和TP53靶向DN 591 366 All SZGR 2.0 genes in this pathway
OSADA ASCL1靶向DN 24 20 All SZGR 2.0 genes in this pathway
Bernard PPAPDC1B目标DN 58 39 All SZGR 2.0 genes in this pathway
Bredemeyer抹布通过ATM而不是通过NFKB向上发出信号 49 32 All SZGR 2.0 genes in this pathway
Ruiz TNC靶向DN 142 79 All SZGR 2.0 genes in this pathway
Rutella对CSF2RB和IL4的响应 338 225 All SZGR 2.0 genes in this pathway
Rutella对HGF的反应 418 282 All SZGR 2.0 genes in this pathway
Rutella对HGF与CSF2RB和IL4的反应 408 276 All SZGR 2.0 genes in this pathway
Valk AML群集10 33 22 All SZGR 2.0 genes in this pathway
val aml与evi1 25 15 All SZGR 2.0 genes in this pathway
Yagi AML带有Inv 16易位 422 277 All SZGR 2.0 genes in this pathway
开罗肝母细胞瘤 207 143 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway
Hirsch细胞转化特征dn 103 67 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505 328 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 3 DN 918 550 All SZGR 2.0 genes in this pathway
双龙通过TSC2敏感血清 39 25 All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向DN 553 343 All SZGR 2.0 genes in this pathway
ikeda mir1靶向 53 39 All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516 308 All SZGR 2.0 genes in this pathway
NABA ECM糖蛋白 196 99 All SZGR 2.0 genes in this pathway
NABA CORE MATRISOME 275 148 All SZGR 2.0 genes in this pathway
NABA MATRISOME 1028 559 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 Target position miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
mir-1/206 1238 1244 1a hsa-miR-1 UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZ Uggaauguaaggaagugugugg
HSA-MIR-613 AGGAAUGUUCCUUCUUUGCC
miR-145 1574年 1580 1a HSA-MIR-145 guccaguuucccaggaaucccuu
miR-15/16/195/424/497 673 679 M8 HSA-MIR-15Abrain uagcagcacauaugguugug
hsa-miR-16brain UAGCAGCACGUAAAUAUUGGCG
HSA-MIR-15Bbrain UAGCAGCACAUCAUGGUUUACA
HSA-MIR-195SZ uagcagaaaaauauuggc
hsa-miR-424 CAGCAGCAAUUCAUGUUUUGAA
HSA-MIR-497 cagcagcacacuguguuugu
miR-17-5p/20/93.mr/106/519.d 1671 1677 M8 HSA-MIR-17-5P caaagugcuuacugcagguagu
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ caaagugcuugugcagguag
HSA-MIR-519D caaagugccucccuuuagugugu
miR-18 1020 1026 M8 HSA-MIR-18A uaagguggaugugcagaua
HSA-MIR-18B UAAGGUGCAUCUAGUGCAGUUA
miR-181 1189 1196 1A，M8 HSA-MIR-181Abrain AACAUUCAACGCUGUCGGUGAGU
HSA-MIR-181BSZ aacauucauugcugucggggg
HSA-MIR-181Cbrain AACAUUCAACCUGUCGGUGAGU
HSA-MIR-181Dbrain aacauucauuguugucggggguggguu
miR-21 1592年 1598年 M8 hsa-miR-21brain UAGCUUAUCAGACUGAUGUUGA
hsa-miR-590 gagcuuauucauaaaaagugcag
mir-216 1203 1209 M8 hsa-miR-216 uaaucucagcuggcaacugug
mir-223 193 199 M8 hsa-miR-223 ugucuuugucaauacccc
miR-28 1524 1530 M8 hsa-miR-28brain Aaggagcucacagucuauugag
mir-326 388 394 M8 hsa-miR-326 CCUCUGGGCCCUUCCUCCAG
mir-331 833 839 M8 hsa-miR-331brain GCCCCUGGGCCUAUCCUAGAA
mir-335 2270 2276 M8 hsa-miR-335brain UCAAGAGCAAUAACGAAAAAUAUGU
mir-369-3p 1857 1863 1a hsa-miR-369-3p aauauacaugguugaucuuu
hsa-miR-369-3p aauauacaugguugaucuuu
miR-374 962 968 M8 HSA-MIR-374 uuauaauacaAccugauaagug
HSA-MIR-374 uuauaauacaAccugauaagug
mir-410 964 970 1a hsa-miR-410 aauauaacacagauggcugu
miR-495 2010年 2016 1a HSA-MIR-495brain Aaacaaacauggugcacuuuuu
HSA-MIR-495brain Aaacaaacauggugcacuuuuu
mir-505 1186 1192 1a hsa-miR-505 gucaacuugcugguuccuc
hsa-miR-505 gucaacuugcugguuccuc
mir-544 160 166 M8 hsa-miR-544 auucugcauuuuuuagcaagu
mir-9 216 222 M8 hsa-miR-9SZ UCUUUGGUUAUCUAGCUGUAUGA
mir-93.hd/291-3p/294/295/302/372/373/520 1670 1676 M8 HSA-MIR-93brain aaagugcuguucgugcagguag
hsa-miR-302a uaagugcuugcauguuuguga
hsa-miR-302b UAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302c uaagugcuuccauguucagugg
hsa-miR-302d Uaagugcuauguugugugu
HSA-MIR-372 AAAGUGCUGCGACAUUUGAGCGU
HSA-MIR-373 Gaagugcuucgauuuggggugu
HSA-MIR-520E Aaagugcuuuuuugaggg
hsa-miR-520a AAAGUGCUUCCCUUUGGACUGU
hsa-miR-520b aaagugcuuuuuuagaggg
hsa-miR-520c aaagugcuuuuuuaggggug
hsa-miR-520d aaaguguuugugggguggguu