Gene Page:CYB5R2

Summary?
GeneID 51700
Symbol CYB5R2
Synonyms B5R.2
Description cytochrome b5 reductase 2
Reference MIM:608342|HGNC:HGNC:24376|Ensembl:ENSG00000166394|HPRD:06435|Vega:OTTHUMG00000165665
Gene type protein-coding
Map location 11p15.4
Pascal p-value 0.59
Sherlock p-value 0.024
Fetal beta -2.142
eGene Cerebellar Hemisphere
Myers' cis & trans
元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs7580088 chr2 171733349 CYB5R2 51700 0.06 trans
rs1894921 chr2 171737414 CYB5R2 51700 0.06 trans
rs4893866 chr2 177363635 CYB5R2 51700 0.05 trans
rs973234 chr3 189840350 CYB5R2 51700 0.15 trans
rs9307467 chr4 120029331 CYB5R2 51700 0.04 trans
rs17152736 chr7 79290748 CYB5R2 51700 0.12 trans
rs6482363 chr10 24368607 CYB5R2 51700 0.06 trans
rs1341055 chr10 112607604 CYB5R2 51700 0.06 trans
rs17109739 chr14 80148280 CYB5R2 51700 0.1 trans
rs17109778 chr14 80170572 CYB5R2 51700 0.14 trans
rs2072968 chr20 39999915 CYB5R2 51700 0.18 trans
rs7276414 chr21 16489575 CYB5R2 51700 0.13 trans
rs7888140 chrX 19825933 CYB5R2 51700 0.07 trans
rs4076909 chrX 71329672 CYB5R2 51700 0.03 trans
rs1857642 chrX 136154060 CYB5R2 51700 0.07 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),圣2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
HOLLMANN APOPTOSIS VIA CD40 DN 267 178 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL DN 198 110 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS LOBULAR NORMAL DN 69 43 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS DUCTAL NORMAL DN 91 53 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST LOBULAR CARCINOMA VS LOBULAR NORMAL UP 94 59 All SZGR 2.0 genes in this pathway
SENESE HDAC1 TARGETS UP 457 269 All SZGR 2.0 genes in this pathway
SENESE HDAC3 TARGETS UP 501 327 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP 293 179 All SZGR 2.0 genes in this pathway
YORDY RECIPROCAL REGULATION BY ETS1 AND SP100 DN 87 48 All SZGR 2.0 genes in this pathway
YANG BREAST CANCER ESR1 DN 25 15 All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS 734 436 All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648 385 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 2 DN 464 276 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 1 DN 169 102 All SZGR 2.0 genes in this pathway
ONDER CDH1 TARGETS 3 DN 59 32 All SZGR 2.0 genes in this pathway
SATO SILENCED BY METHYLATION IN PANCREATIC CANCER 1 419 273 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL UP 648 398 All SZGR 2.0 genes in this pathway
VANTVEER BREAST CANCER ESR1 DN 240 153 All SZGR 2.0 genes in this pathway
MIKKELSEN ES ICP WITH H3K4ME3 718 401 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC ICP WITH H3K4ME3 445 257 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2 182 102 All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP 242 159 All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS SENESCENT 572 352 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8 TARGETS DN 784 464 All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725 838 All SZGR 2.0 genes in this pathway