Gene Page:CAB39

Summary?
GeneID 51719
Symbol CAB39
Synonyms CGI-66|MO25
Description calcium binding protein 39
Reference MIM:612174|HGNC:HGNC:20292|Ensembl:ENSG00000135932|HPRD:10091|Vega:OTTHUMG00000133220
Gene type protein-coding
Map location 2q37.1
Pascal p-value 0.84
Sherlock p-value 0.333
Fetal beta -0.469
DMG 1 (# studies)

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg13313294 2 231646024 CAB39 1.799E-4 -0.334 0.034 DMG:Wockner_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B Experimental Source PubMed ID
BCKDK - branched chain ketoacid dehydrogenase kinase Affinity Capture-MS BioGRID 17353931
CUL2 MGC131970 cullin 2 Affinity Capture-MS BioGRID 17353931
FLJ10213 - hypothetical protein FLJ10213 Affinity Capture-MS BioGRID 17353931
MOBKL3 2C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3 MOB1, Mps One Binder kinase activator-like 3 (yeast) Affinity Capture-MS BioGRID 17353931
PRKAA1 AMPK | AMPKa1 | MGC33776 | MGC57364 protein kinase, AMP-activated, alpha 1 catalytic subunit - HPRD 8910387
RAD51 BRCC5 | HRAD51 | HsRad51 | HsT16930 | RAD51A | RECA RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) Affinity Capture-MS BioGRID 17353931
STK11 LKB1 | PJS serine/threonine kinase 11 Affinity Capture-Western BioGRID 15561763
STK11 LKB1 | PJS serine/threonine kinase 11 - HPRD 14676191
STRADA FLJ90524 | LYK5 | NY-BR-96 | PMSE | STRAD | Stlk STE20-related kinase adaptor alpha - HPRD,BioGRID 14730349|15561763
STRADB ALS2CR2 | CALS-21 | ILPIP | ILPIPA | MGC102916 | PAPK | PRO1038 STE20-related kinase adaptor beta - HPRD 14676191
TIMM13 TIM13 | TIM13B | TIMM13A | TIMM13B | ppv1 translocase of inner mitochondrial membrane 13 homolog (yeast) Affinity Capture-MS BioGRID 17353931
VHL HRCA1 | RCA1 | VHL1 von Hippel-Lindau tumor suppressor Affinity Capture-MS BioGRID 17353931


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG MTOR SIGNALING PATHWAY 52 40 All SZGR 2.0 genes in this pathway
PID LKB1 PATHWAY 47 37 All SZGR 2.0 genes in this pathway
REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE 19 16 All SZGR 2.0 genes in this pathway
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE 87 64 All SZGR 2.0 genes in this pathway
REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 15 13 All SZGR 2.0 genes in this pathway
REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK 18 15 All SZGR 2.0 genes in this pathway
REACTOME PKB MEDIATED EVENTS 29 23 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY INSULIN RECEPTOR 108 72 All SZGR 2.0 genes in this pathway
REACTOME PI3K CASCADE 71 51 All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS UP 473 314 All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 All SZGR 2.0 genes in this pathway
COLDREN GEFITINIB RESISTANCE DN 230 115 All SZGR 2.0 genes in this pathway
JAZAG TGFB1 SIGNALING VIA SMAD4 UP 108 66 All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP 1037 673 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 5 482 296 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022 619 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229 713 All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE BY UV 62 43 All SZGR 2.0 genes in this pathway
KYNG DNA DAMAGE DN 195 135 All SZGR 2.0 genes in this pathway
MASSARWEH TAMOXIFEN RESISTANCE UP 578 341 All SZGR 2.0 genes in this pathway
CHEN HOXA5 TARGETS 9HR UP 223 132 All SZGR 2.0 genes in this pathway
MOOTHA PGC 420 269 All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS UNANNOTATED DN 193 112 All SZGR 2.0 genes in this pathway
MIKKELSEN MCV6 LCP WITH H3K4ME3 162 80 All SZGR 2.0 genes in this pathway
MIKKELSEN MEF LCP WITH H3K4ME3 128 68 All SZGR 2.0 genes in this pathway
MIKKELSEN IPS LCP WITH H3K4ME3 174 100 All SZGR 2.0 genes in this pathway
MIKKELSEN ES LCP WITH H3K4ME3 142 80 All SZGR 2.0 genes in this pathway
MIKKELSEN NPC LCP WITH H3K4ME3 58 34 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 24HR DN 505 328 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137 655 All SZGR 2.0 genes in this pathway
ABDELMOHSEN ELAVL4 TARGETS 16 13 All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF 516 308 All SZGR 2.0 genes in this pathway