Gene Page:AHI1

Summary?
GeneID 54806
Symbol AHI1
Synonyms AHI-1|JBTS3|ORF1|dJ71N10.1
Description Abelson helper integration site 1
Reference MIM:608894|HGNC:HGNC:21575|Ensembl:ENSG00000135541|HPRD:10597|Vega:OTTHUMG00000015631
Gene type protein-coding
Map location 6q23.3
Pascal p-value 0.055
Sherlock p-value 0.372
Fetal beta -0.912
eGene Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Hippocampus
Nucleus accumbens basal ganglia
Putamen basal ganglia
Myers' cis & trans
Support Ascano FMRP targets

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Association A combined odds ratio method (Sun et al. 2008), association studies 2 Link to SZGene
Literature High-throughput literature-search 与精神分裂症Co-occurance关键词: schizophrenia,schizophrenic,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs10994209 chr10 61877705 AHI1 54806 0.1 trans
rs72556118 6 135623751 AHI1 ENSG00000135541.16 2.718E-6 0 194636 gtex_brain_putamen_basal
rs3833484 6 135623752 AHI1 ENSG00000135541.16 2.717E-6 0 194635 gtex_brain_putamen_basal
rs6928977 6 135626348 AHI1 ENSG00000135541.16 3.766E-6 0 192039 gtex_brain_putamen_basal
rs6935146 6 135627369 AHI1 ENSG00000135541.16 1.501E-6 0 191018 gtex_brain_putamen_basal
rs6918097 6 135635549 AHI1 ENSG00000135541.16 2.313E-6 0 182838 gtex_brain_putamen_basal
rs9321500 6 135641369 AHI1 ENSG00000135541.16 4.072E-6 0 177018 gtex_brain_putamen_basal
rs9321501 6 135641417 AHI1 ENSG00000135541.16 3.35E-6 0 176970 gtex_brain_putamen_basal
rs2064430 6 135642756 AHI1 ENSG00000135541.16 3.35E-6 0 175631 gtex_brain_putamen_basal
rs2064431 6 135645203 AHI1 ENSG00000135541.16 3.357E-6 0 173184 gtex_brain_putamen_basal
rs1012645 6 135645447 AHI1 ENSG00000135541.16 3.355E-6 0 172940 gtex_brain_putamen_basal
rs2179779 6 135649816 AHI1 ENSG00000135541.16 2.74E-6 0 168571 gtex_brain_putamen_basal
rs6570001 6 135651721 AHI1 ENSG00000135541.16 3.386E-7 0 166666 gtex_brain_putamen_basal
rs2614279 6 135653357 AHI1 ENSG00000135541.16 2.82E-6 0 165030 gtex_brain_putamen_basal
rs2614278 6 135653398 AHI1 ENSG00000135541.16 3.505E-6 0 164989 gtex_brain_putamen_basal
rs9321502 6 135656252 AHI1 ENSG00000135541.16 1.321E-6 0 162135 gtex_brain_putamen_basal
rs2746421 6 135661629 AHI1 ENSG00000135541.16 3.515E-6 0 156758 gtex_brain_putamen_basal
rs2746425 6 135664365 AHI1 ENSG00000135541.16 3.517E-6 0 154022 gtex_brain_putamen_basal
rs2746426 6 135666432 AHI1 ENSG00000135541.16 3.696E-6 0 151955 gtex_brain_putamen_basal
rs2746427 6 135669097 AHI1 ENSG00000135541.16 3.522E-6 0 149290 gtex_brain_putamen_basal
rs2746429 6 135673284 AHI1 ENSG00000135541.16 3.349E-6 0 145103 gtex_brain_putamen_basal
rs2746430 6 135673292 AHI1 ENSG00000135541.16 3.876E-6 0 145095 gtex_brain_putamen_basal
rs2614258 6 135677202 AHI1 ENSG00000135541.16 4.141E-7 0 141185 gtex_brain_putamen_basal
rs2614259 6 135677252 AHI1 ENSG00000135541.16 3.352 e-6 0 141135 gtex_brain_putamen_basal
rs2614276 6 135681704 AHI1 ENSG00000135541.16 3.519E-7 0 136683 gtex_brain_putamen_basal
rs7748148 6 135684623 AHI1 ENSG00000135541.16 1.193E-7 0 133764 gtex_brain_putamen_basal
rs2746431 6 135687201 AHI1 ENSG00000135541.16 3.582E-6 0 131186 gtex_brain_putamen_basal
rs2246852 6 135691792 AHI1 ENSG00000135541.16 3.252E-7 0 126595 gtex_brain_putamen_basal
rs6908428 6 135793706 AHI1 ENSG00000135541.16 1.652E-6 0 24681 gtex_brain_putamen_basal
rs12206850 6 135797808 AHI1 ENSG00000135541.16 4.159E-6 0 20579 gtex_brain_putamen_basal
rs11154803 6 135798845 AHI1 ENSG00000135541.16 1.652E-6 0 19542 gtex_brain_putamen_basal
rs4526212 6 135804631 AHI1 ENSG00000135541.16 1.652E-6 0 13756 gtex_brain_putamen_basal
rs9402706 6 135806219 AHI1 ENSG00000135541.16 2.049E-6 0 12168 gtex_brain_putamen_basal
rs7750586 6 135827673 AHI1 ENSG00000135541.16 1.801E-6 0 -9286 gtex_brain_putamen_basal
rs4896153 6 135833463 AHI1 ENSG00000135541.16 2.951E-6 0 -15076 gtex_brain_putamen_basal
rs58761508 6 135835901 AHI1 ENSG00000135541.16 1.804E-6 0 -17514 gtex_brain_putamen_basal
rs9385726 6 135836962 AHI1 ENSG00000135541.16 1.804E-6 0 -18575 gtex_brain_putamen_basal
rs9647635 6 135841056 AHI1 ENSG00000135541.16 1.804E-6 0 -22669 gtex_brain_putamen_basal
rs9399148 6 135844359 AHI1 ENSG00000135541.16 1.804E-6 0 -25972 gtex_brain_putamen_basal
rs200655578 6 135848172 AHI1 ENSG00000135541.16 1.971E-6 0 -29785 gtex_brain_putamen_basal
rs5880258 6 135848175 AHI1 ENSG00000135541.16 1.757E-6 0 -29788 gtex_brain_putamen_basal
rs5880259 6 135867300 AHI1 ENSG00000135541.16 2.077E-6 0 -48913 gtex_brain_putamen_basal
rs11154806 6 135873721 AHI1 ENSG00000135541.16 8.102E-7 0 -55334 gtex_brain_putamen_basal
rs67316642 6 135891670 AHI1 ENSG00000135541.16 1.528E-6 0 -73283 gtex_brain_putamen_basal
rs13208505 6 135893723 AHI1 ENSG00000135541.16 1.815E-6 0 -75336 gtex_brain_putamen_basal
rs761357 6 135902599 AHI1 ENSG00000135541.16 1.72E-6 0 -84212 gtex_brain_putamen_basal
rs4370385 6 135947310 AHI1 ENSG00000135541.16 2.647E-6 0 -128923 gtex_brain_putamen_basal
rs9494308 6 135948804 AHI1 ENSG00000135541.16 1.298E-6 0 -130417 gtex_brain_putamen_basal
rs12211833 6 135950204 AHI1 ENSG00000135541.16 3.677E-6 0 -131817 gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ONKEN UVEAL MELANOMA UP 783 507 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS TOP50 DN 45 26 All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE DN 244 147 All SZGR 2.0 genes in this pathway
BARRIER COLON CANCER RECURRENCE UP 42 28 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 1 UP 276 165 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 2 UP 139 83 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 SIGNATURE 3 UP 341 197 All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781 465 All SZGR 2.0 genes in this pathway
GAUSSMANN MLL AF4 FUSION TARGETS C DN 19 11 All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584 356 All SZGR 2.0 genes in this pathway
HATADA METHYLATED IN LUNG CANCER UP 390 236 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344 180 All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648 385 All SZGR 2.0 genes in this pathway
GALE APL WITH FLT3 MUTATED UP 56 35 All SZGR 2.0 genes in this pathway
ACEVEDO METHYLATED IN LIVER CANCER DN 940 425 All SZGR 2.0 genes in this pathway
LIN NPAS4 TARGETS UP 163 100 All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER DN 238 145 All SZGR 2.0 genes in this pathway
HAN SATB1 TARGETS DN 442 275 All SZGR 2.0 genes in this pathway
POOLA INVASIVE BREAST CANCER UP 288 168 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306 191 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE G2 M 216 124 All SZGR 2.0 genes in this pathway
LIM MAMMARY STEM CELL UP 489 314 All SZGR 2.0 genes in this pathway