Gene Page:ARHGEF38

Summary?
GeneID 54848
Symbol ARHGEF38
Synonyms -
Description Rho guanine nucleotide exchange factor 38
Reference HGNC:HGNC:25968|Ensembl:ENSG00000236699|HPRD:08613|Vega:OTTHUMG00000154752
Gene type protein-coding
Map location 4q24
Pascal p-value 0.136
Fetal beta 0.373
Support CompositeSet

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWAScat Genome-wide Association Studies This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:PGCnp Genome-wide Association Study GWAS
认为:Xu_2012 Whole Exome Sequencing analysis 新创4基因的突变identified by exome sequencing of 795 samples in this study

Section I. Genetics and epigenetics annotation

@认为table

Gene Chromosome Position Ref Alt Transcript AA change Mutation type Sift CG46 Trait Study
ARHGEF38 chr4 106510442 G T NM_001242729
NM_017700		 p.78E>D
p.78E>D		 missense
missense		 Schizophrenia 认为:Xu_2012


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
BENPORATH ES WITH H3K27ME3 1118 744 All SZGR 2.0 genes in this pathway