基因页：UHRF1BP1
概括?
| 基因ID | 54887 |
| 象征 | UHRF1BP1 |
| 同义词 | C6orf107|ICBP90|dJ349A12.1 |
| 描述 | UHRF1结合蛋白1 |
| 参考 | HGNC：HGNC：21216|Ensembl：ENSG00000065060|HPRD：12838|Vega：Otthumg0000000014557 |
| 基因类型 | protein-coding |
| 地图位置 | 6p21 |
| Pascal P值 | 0.373 |
| Fetal beta | -0.308 |
| DMG | 2（＃研究） |
| eGene | 尾状基底神经节 小脑半球 小脑 额叶皮质BA9 下丘脑 梭子基底神经节 迈尔斯的顺式和跨性别 |
| 支持 | Ascano FMRP目标 |
数据源中的基因
| 基因集名称 | 基因组方法 | 描述 | Info |
|---|---|---|---|
| 简历：PGCNP | Genome-wide Association Study | GWAS | |
| DMG：JAFFE_2016 | Genome-wide DNA methylation analysis | 该数据集包括与SZ患者相关的2,104个探针/CPG（n = 108），而在Bonferroni调整后的P <0.05时，其中136个对照。 | 2 |
| DMG:Wockner_2014 | Genome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 2 |
| gsma_iie | 基因组扫描荟萃分析（欧洲官方样品） | Psr: 0.04433 |
第一节遗传学和表观遗传学注释
Differentially methylated gene
Differentially methylated gene| 探测 | 染色体 | 位置 | Nearest gene | P (dis) | beta（dis） | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| CG19355881 | 6 | 34759549 | UHRF1BP1 | 1.779E-4 | -0.286 | 0.034 | DMG:Wockner_2014 |
| CG00385620 | 6 | 34759158 | UHRF1BP1 | 5.97E-8 | 0.021 | 1.51E-5 | DMG：JAFFE_2016 |
eQTL annotation
| SNP ID | 染色体 | 位置 | eGene | 基因Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| RS1574259 | CHR2 | 173313452 | UHRF1BP1 | 54887 | 0.17 | 反式 | ||
| RS412392 | 6 | 34549699 | UHRF1BP1 | ENSG0000000065060.12 | 1.452E-11 | 0 | -210158 | gtex_brain_putamen_basal |
| RS1201874 | 6 | 34549810 | UHRF1BP1 | ENSG0000000065060.12 | 1.428E-11 | 0 | -210047 | gtex_brain_putamen_basal |
| RS1201873 | 6 | 34550657 | UHRF1BP1 | ENSG0000000065060.12 | 1.258e-11 | 0 | -209200 | gtex_brain_putamen_basal |
| RS188190 | 6 | 34551086 | UHRF1BP1 | ENSG0000000065060.12 | 1.71e-11 | 0 | -208771 | gtex_brain_putamen_basal |
| RS205286 | 6 | 34551334 | UHRF1BP1 | ENSG0000000065060.12 | 1.683e-11 | 0 | -208523 | gtex_brain_putamen_basal |
| RS205283 | 6 | 34553048 | UHRF1BP1 | ENSG0000000065060.12 | 1.643E-10 | 0 | -206809 | gtex_brain_putamen_basal |
| RS205262 | 6 | 34563164 | UHRF1BP1 | ENSG0000000065060.12 | 1.008e-6 | 0 | -196693 | gtex_brain_putamen_basal |
| RS205260 | 6 | 34563958 | UHRF1BP1 | ENSG0000000065060.12 | 1.566E-11 | 0 | -195899 | gtex_brain_putamen_basal |
| RS205259 | 6 | 34564066 | UHRF1BP1 | ENSG0000000065060.12 | 1.531e-11 | 0 | -195791 | gtex_brain_putamen_basal |
| RS205258 | 6 | 34564243 | UHRF1BP1 | ENSG0000000065060.12 | 1.527e-11 | 0 | -195614 | gtex_brain_putamen_basal |
| RS2814972 | 6 | 34566975 | UHRF1BP1 | ENSG0000000065060.12 | 1.543e-11 | 0 | -192882 | gtex_brain_putamen_basal |
| RS2262245 | 6 | 34567694 | UHRF1BP1 | ENSG0000000065060.12 | 1.576e-11 | 0 | -192163 | gtex_brain_putamen_basal |
| RS200798135 | 6 | 34569481 | UHRF1BP1 | ENSG0000000065060.12 | 4.264E-9 | 0 | -190376 | gtex_brain_putamen_basal |
| rs2235569 | 6 | 34570070 | UHRF1BP1 | ENSG0000000065060.12 | 1.005E-11 | 0 | -189787 | gtex_brain_putamen_basal |
| rs2235568 | 6 | 34570094 | UHRF1BP1 | ENSG0000000065060.12 | 1.006E-11 | 0 | -189763 | gtex_brain_putamen_basal |
| RS2814974 | 6 | 34572028 | UHRF1BP1 | ENSG0000000065060.12 | 1.019e-11 | 0 | -187829 | gtex_brain_putamen_basal |
| RS2814975 | 6 | 34573213 | UHRF1BP1 | ENSG0000000065060.12 | 6.358E-12 | 0 | -186644 | gtex_brain_putamen_basal |
| rs57434246 | 6 | 34575426 | UHRF1BP1 | ENSG0000000065060.12 | 1.03e-11 | 0 | -184431 | gtex_brain_putamen_basal |
| RS2814976 | 6 | 34576237 | UHRF1BP1 | ENSG0000000065060.12 | 1.035e-11 | 0 | -183620 | gtex_brain_putamen_basal |
| RS2814978 | 6 | 3457776 | UHRF1BP1 | ENSG0000000065060.12 | 1.924E-11 | 0 | -182081 | gtex_brain_putamen_basal |
| RS2814979 | 6 | 34578425 | UHRF1BP1 | ENSG0000000065060.12 | 1.614e-11 | 0 | -181432 | gtex_brain_putamen_basal |
| RS2744974 | 6 | 34579431 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -180426 | gtex_brain_putamen_basal |
| RS2744973 | 6 | 34580221 | UHRF1BP1 | ENSG0000000065060.12 | 3.59e-11 | 0 | -179636 | gtex_brain_putamen_basal |
| RS2814981 | 6 | 34581055 | UHRF1BP1 | ENSG0000000065060.12 | 1.604e-11 | 0 | -178802 | gtex_brain_putamen_basal |
| RS4711396 | 6 | 34582220 | UHRF1BP1 | ENSG0000000065060.12 | 1.065E-8 | 0 | -177637 | gtex_brain_putamen_basal |
| RS2263329 | 6 | 34595543 | UHRF1BP1 | ENSG0000000065060.12 | 2.005e-10 | 0 | -164314 | gtex_brain_putamen_basal |
| RS2814984 | 6 | 34597513 | UHRF1BP1 | ENSG0000000065060.12 | 1.627e-11 | 0 | -162344 | gtex_brain_putamen_basal |
| rs398094093 | 6 | 34599738 | UHRF1BP1 | ENSG0000000065060.12 | 1.536e-11 | 0 | -160119 | gtex_brain_putamen_basal |
| RS66760501 | 6 | 34602847 | UHRF1BP1 | ENSG0000000065060.12 | 2.468e-11 | 0 | -157010 | gtex_brain_putamen_basal |
| RS2814987 | 6 | 34605145 | UHRF1BP1 | ENSG0000000065060.12 | 1.73e-11 | 0 | -154712 | gtex_brain_putamen_basal |
| RS2814988 | 6 | 34608480 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -151377年 | gtex_brain_putamen_basal |
| RS9469835 | 6 | 34611001 | UHRF1BP1 | ENSG0000000065060.12 | 1.496E-9 | 0 | -148856 | gtex_brain_putamen_basal |
| RS34094891 | 6 | 34614822 | UHRF1BP1 | ENSG0000000065060.12 | 1.54E-11 | 0 | -145035 | gtex_brain_putamen_basal |
| RS2814991 | 6 | 34615443 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -144414 | gtex_brain_putamen_basal |
| RS2744959 | 6 | 34616654 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -143203 | gtex_brain_putamen_basal |
| RS2814992 | 6 | 34617144 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -142713 | gtex_brain_putamen_basal |
| RS2744958 | 6 | 34618356 | UHRF1BP1 | ENSG0000000065060.12 | 1.172E-8 | 0 | -141501 | gtex_brain_putamen_basal |
| RS2744957 | 6 | 34618516 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -141341 | gtex_brain_putamen_basal |
| RS2814995 | 6 | 34621171 | UHRF1BP1 | ENSG0000000065060.12 | 2.19E-11 | 0 | -138686 | gtex_brain_putamen_basal |
| RS2744949 | 6 | 34633862 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -125995 | gtex_brain_putamen_basal |
| rs2815001 | 6 | 34634353 | UHRF1BP1 | ENSG0000000065060.12 | 1.518e-11 | 0 | -125504 | gtex_brain_putamen_basal |
| rs2815004 | 6 | 34636268 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -123589 | gtex_brain_putamen_basal |
| RS2395598 | 6 | 34640686 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -119171 | gtex_brain_putamen_basal |
| RS2395599 | 6 | 34641415 | UHRF1BP1 | ENSG0000000065060.12 | 1.624e-11 | 0 | -118442 | gtex_brain_putamen_basal |
| RS2744943 | 6 | 34643179 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -116678 | gtex_brain_putamen_basal |
| RS2814942 | 6 | 34644261 | UHRF1BP1 | ENSG0000000065060.12 | 1.835E-11 | 0 | -115596 | gtex_brain_putamen_basal |
| RS6937784 | 6 | 34644276 | UHRF1BP1 | ENSG0000000065060.12 | 1.835E-11 | 0 | -115581 | gtex_brain_putamen_basal |
| RS2744941 | 6 | 34646917 | UHRF1BP1 | ENSG0000000065060.12 | 2.952E-11 | 0 | -112940 | gtex_brain_putamen_basal |
| RS2814945 | 6 | 34647978 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -111879 | gtex_brain_putamen_basal |
| RS2814946 | 6 | 34651180 | UHRF1BP1 | ENSG0000000065060.12 | 2.754e-10 | 0 | -108677 | gtex_brain_putamen_basal |
| RS67229195 | 6 | 34651290 | UHRF1BP1 | ENSG0000000065060.12 | 1.698E-7 | 0 | -108567 | gtex_brain_putamen_basal |
| RS201444562 | 6 | 34651302 | UHRF1BP1 | ENSG0000000065060.12 | 2.406e-11 | 0 | -108555 | gtex_brain_putamen_basal |
| RS2814947 | 6 | 34653268 | UHRF1BP1 | ENSG0000000065060.12 | 2.508E-10 | 0 | -106589 | gtex_brain_putamen_basal |
| RS2744961 | 6 | 34655000 | UHRF1BP1 | ENSG0000000065060.12 | 1.726E-10 | 0 | -104857 | gtex_brain_putamen_basal |
| RS2814949 | 6 | 34656722 | UHRF1BP1 | ENSG0000000065060.12 | 6.1E-11 | 0 | -103135 | gtex_brain_putamen_basal |
| RS2744944 | 6 | 34658080 | UHRF1BP1 | ENSG0000000065060.12 | 1.725E-10 | 0 | -101777 | gtex_brain_putamen_basal |
| RS7771778 | 6 | 34660324 | UHRF1BP1 | ENSG0000000065060.12 | 1.626e-11 | 0 | -99533 | gtex_brain_putamen_basal |
| RS199510489 | 6 | 34661448 | UHRF1BP1 | ENSG0000000065060.12 | 1.429E-6 | 0 | -98409 | gtex_brain_putamen_basal |
| RS3800458 | 6 | 34663487 | UHRF1BP1 | ENSG0000000065060.12 | 1.692E-10 | 0 | -96370 | gtex_brain_putamen_basal |
| RS7742652 | 6 | 34667075 | UHRF1BP1 | ENSG0000000065060.12 | 1.616e-11 | 0 | -92782 | gtex_brain_putamen_basal |
| RS9368830 | 6 | 34668635 | UHRF1BP1 | ENSG0000000065060.12 | 2.332e-12 | 0 | -91222 | gtex_brain_putamen_basal |
| RS201163058 | 6 | 34669134 | UHRF1BP1 | ENSG0000000065060.12 | 5.899e-11 | 0 | -90723 | gtex_brain_putamen_basal |
| RS58655892 | 6 | 34669148 | UHRF1BP1 | ENSG0000000065060.12 | 3.324e-7 | 0 | -90709 | gtex_brain_putamen_basal |
| RS9380454 | 6 | 34669384 | UHRF1BP1 | ENSG0000000065060.12 | 1.643e-11 | 0 | -90473 | gtex_brain_putamen_basal |
| RS7759128 | 6 | 34670395 | UHRF1BP1 | ENSG0000000065060.12 | 2.166E-10 | 0 | -89462 | gtex_brain_putamen_basal |
| rs7741398 | 6 | 34670623 | UHRF1BP1 | ENSG0000000065060.12 | 1.76e-11 | 0 | -89234 | gtex_brain_putamen_basal |
| RS7763987 | 6 | 34670975 | UHRF1BP1 | ENSG0000000065060.12 | 1.617E-11 | 0 | -88882 | gtex_brain_putamen_basal |
| RS9348950 | 6 | 34673678 | UHRF1BP1 | ENSG0000000065060.12 | 1.509E-11 | 0 | -86179 | gtex_brain_putamen_basal |
| RS9357181 | 6 | 34673833 | UHRF1BP1 | ENSG0000000065060.12 | 1.616e-11 | 0 | -86024 | gtex_brain_putamen_basal |
| RS201659735 | 6 | 34677141 | UHRF1BP1 | ENSG0000000065060.12 | 6.415e-8 | 0 | -82716 | gtex_brain_putamen_basal |
| RS149313131 | 6 | 34679433 | UHRF1BP1 | ENSG0000000065060.12 | 9.105e-11 | 0 | -80424 | gtex_brain_putamen_basal |
| RS369969803 | 6 | 34679437 | UHRF1BP1 | ENSG0000000065060.12 | 2.417E-11 | 0 | -80420 | gtex_brain_putamen_basal |
| RS9368832 | 6 | 34679587 | UHRF1BP1 | ENSG0000000065060.12 | 1.619e-11 | 0 | -80270 | gtex_brain_putamen_basal |
| rs9366862 | 6 | 34679935 | UHRF1BP1 | ENSG0000000065060.12 | 9.186e-9 | 0 | -79922 | gtex_brain_putamen_basal |
| RS12201281 | 6 | 34681091 | UHRF1BP1 | ENSG0000000065060.12 | 1.605e-11 | 0 | -78766 | gtex_brain_putamen_basal |
| rs9366863 | 6 | 34688946 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -70911 | gtex_brain_putamen_basal |
| RS10947521 | 6 | 34689377 | UHRF1BP1 | ENSG0000000065060.12 | 1.792E-11 | 0 | -70480 | gtex_brain_putamen_basal |
| RS9380455 | 6 | 34690778 | UHRF1BP1 | ENSG0000000065060.12 | 2.731E-10 | 0 | -69079 | gtex_brain_putamen_basal |
| rs6929567 | 6 | 34692735 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -67122 | gtex_brain_putamen_basal |
| RS10807141 | 6 | 34693111 | UHRF1BP1 | ENSG0000000065060.12 | 8.847e-12 | 0 | -66746 | gtex_brain_putamen_basal |
| rs10738078 | 6 | 34693917 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -65940 | gtex_brain_putamen_basal |
| rs4513788 | 6 | 34694779 | UHRF1BP1 | ENSG0000000065060.12 | 2.099E-11 | 0 | -65078 | gtex_brain_putamen_basal |
| RS2814951 | 6 | 34695081 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -64776 | gtex_brain_putamen_basal |
| RS7758082 | 6 | 34696700 | UHRF1BP1 | ENSG0000000065060.12 | 3.459e-11 | 0 | -63157 | gtex_brain_putamen_basal |
| RS13206387 | 6 | 34696792 | UHRF1BP1 | ENSG0000000065060.12 | 5.522e-11 | 0 | -63065 | gtex_brain_putamen_basal |
| RS2814952 | 6 | 34697379 | UHRF1BP1 | ENSG0000000065060.12 | 8.106E-13 | 0 | -62478 | gtex_brain_putamen_basal |
| RS2814953 | 6 | 34697767 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -62090 | gtex_brain_putamen_basal |
| RS2814955 | 6 | 34698970 | UHRF1BP1 | ENSG0000000065060.12 | 1.061e-11 | 0 | -60887 | gtex_brain_putamen_basal |
| RS2764210 | 6 | 34699049 | UHRF1BP1 | ENSG0000000065060.12 | 3.636E-11 | 0 | -60808 | gtex_brain_putamen_basal |
| RS2814956 | 6 | 34699109 | UHRF1BP1 | ENSG0000000065060.12 | 2.586E-11 | 0 | -60748 | gtex_brain_putamen_basal |
| RS397722291 | 6 | 34701981 | UHRF1BP1 | ENSG0000000065060.12 | 3.762e-11 | 0 | -57876 | gtex_brain_putamen_basal |
| RS2814957 | 6 | 34702689 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -57168 | gtex_brain_putamen_basal |
| RS2814958 | 6 | 34702958 | UHRF1BP1 | ENSG0000000065060.12 | 1.768e-11 | 0 | -56899 | gtex_brain_putamen_basal |
| rs2477507 | 6 | 34703599 | UHRF1BP1 | ENSG0000000065060.12 | 1.725E-11 | 0 | -56258 | gtex_brain_putamen_basal |
| rs2477508 | 6 | 34703695 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -56162 | gtex_brain_putamen_basal |
| RS2764211 | 6 | 34704613 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -55244 | gtex_brain_putamen_basal |
| RS2764197 | 6 | 34705055 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -54802 | gtex_brain_putamen_basal |
| rs2492860 | 6 | 34705530 | UHRF1BP1 | ENSG0000000065060.12 | 5.617E-11 | 0 | -54327 | gtex_brain_putamen_basal |
| RS2814959 | 6 | 34705947 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -53910 | gtex_brain_putamen_basal |
| RS2764198 | 6 | 34706128 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -53729 | gtex_brain_putamen_basal |
| RS6940215 | 6 | 34706358 | UHRF1BP1 | ENSG0000000065060.12 | 2.594E-6 | 0 | -53499 | gtex_brain_putamen_basal |
| RS2814961 | 6 | 34706951 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -52906 | gtex_brain_putamen_basal |
| RS2764201 | 6 | 34708850 | UHRF1BP1 | ENSG0000000065060.12 | 6.337E-9 | 0 | -51007 | gtex_brain_putamen_basal |
| RS2814963 | 6 | 34708908 | UHRF1BP1 | ENSG0000000065060.12 | 1.288E-9 | 0 | -50949 | gtex_brain_putamen_basal |
| rs398110017 | 6 | 34709796 | UHRF1BP1 | ENSG0000000065060.12 | 1.858e-11 | 0 | -50061 | gtex_brain_putamen_basal |
| rs9462006 | 6 | 34710327 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -49530 | gtex_brain_putamen_basal |
| rs2492861 | 6 | 34710934 | UHRF1BP1 | ENSG0000000065060.12 | 1.507e-11 | 0 | -48923 | gtex_brain_putamen_basal |
| rs398001125 | 6 | 34711590 | UHRF1BP1 | ENSG0000000065060.12 | 1.535e-11 | 0 | -48267 | gtex_brain_putamen_basal |
| RS2814966 | 6 | 34712232 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -47625 | gtex_brain_putamen_basal |
| RS2814967 | 6 | 34712838 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -47019 | gtex_brain_putamen_basal |
| RS2764206 | 6 | 34712900 | UHRF1BP1 | ENSG0000000065060.12 | 1.689e-11 | 0 | -46957 | gtex_brain_putamen_basal |
| RS2764207 | 6 | 34712998 | UHRF1BP1 | ENSG0000000065060.12 | 7.086E-11 | 0 | -46859 | gtex_brain_putamen_basal |
| RS2814968 | 6 | 34713138 | UHRF1BP1 | ENSG0000000065060.12 | 7.092E-11 | 0 | -46719 | gtex_brain_putamen_basal |
| RS2814969 | 6 | 34713399 | UHRF1BP1 | ENSG0000000065060.12 | 2.433E-11 | 0 | -46458 | gtex_brain_putamen_basal |
| RS2814970 | 6 | 34713500 | UHRF1BP1 | ENSG0000000065060.12 | 1.69e-11 | 0 | -46357 | gtex_brain_putamen_basal |
| RS2814971 | 6 | 34714209 | UHRF1BP1 | ENSG0000000065060.12 | 1.69e-11 | 0 | -45648 | gtex_brain_putamen_basal |
| RS2764208 | 6 | 34714322 | UHRF1BP1 | ENSG0000000065060.12 | 7.104e-11 | 0 | -45535 | gtex_brain_putamen_basal |
| rs7755982 | 6 | 34715297 | UHRF1BP1 | ENSG0000000065060.12 | 7.122e-11 | 0 | -44560 | gtex_brain_putamen_basal |
| rs7756009 | 6 | 34715395 | UHRF1BP1 | ENSG0000000065060.12 | 7.122e-11 | 0 | -44462 | gtex_brain_putamen_basal |
| rs912716 | 6 | 34715761 | UHRF1BP1 | ENSG0000000065060.12 | 1.691E-11 | 0 | -44096 | gtex_brain_putamen_basal |
| rs3734268 | 6 | 34716028 | UHRF1BP1 | ENSG0000000065060.12 | 7.134e-11 | 0 | -43829 | gtex_brain_putamen_basal |
| rs9462009 | 6 | 34716330 | UHRF1BP1 | ENSG0000000065060.12 | 1.691E-11 | 0 | -43527 | gtex_brain_putamen_basal |
| rs9462010 | 6 | 34716605 | UHRF1BP1 | ENSG0000000065060.12 | 7.179e-11 | 0 | -43252 | gtex_brain_putamen_basal |
| rs9462011 | 6 | 34716985 | UHRF1BP1 | ENSG0000000065060.12 | 7.64e-11 | 0 | -42872 | gtex_brain_putamen_basal |
| rs35839188 | 6 | 34717083 | UHRF1BP1 | ENSG0000000065060.12 | 2.146E-7 | 0 | -42774 | gtex_brain_putamen_basal |
| RS9469856 | 6 | 34717085 | UHRF1BP1 | ENSG0000000065060.12 | 1.476E-7 | 0 | -42772 | gtex_brain_putamen_basal |
| RS59162539 | 6 | 34717783 | UHRF1BP1 | ENSG0000000065060.12 | 8.266e-12 | 0 | -42074 | gtex_brain_putamen_basal |
| RS9296127 | 6 | 34719628 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -40229 | gtex_brain_putamen_basal |
| RS9469857 | 6 | 34719793 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -40064 | gtex_brain_putamen_basal |
| RS9469858 | 6 | 34720211 | UHRF1BP1 | ENSG0000000065060.12 | 2.027E-11 | 0 | -39646 | gtex_brain_putamen_basal |
| rs6929470 | 6 | 34720324 | UHRF1BP1 | ENSG0000000065060.12 | 3.398E-6 | 0 | -39533 | gtex_brain_putamen_basal |
| rs6907244 | 6 | 34720411 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -39446 | gtex_brain_putamen_basal |
| RS6457787 | 6 | 34721041 | UHRF1BP1 | ENSG0000000065060.12 | 3.112E-9 | 0 | -38816 | gtex_brain_putamen_basal |
| RS6457788 | 6 | 34721067 | UHRF1BP1 | ENSG0000000065060.12 | 4.89e-11 | 0 | -38790 | gtex_brain_putamen_basal |
| RS6457789 | 6 | 34721128 | UHRF1BP1 | ENSG0000000065060.12 | 4.89e-11 | 0 | -38729 | gtex_brain_putamen_basal |
| RS7755926 | 6 | 34722574 | UHRF1BP1 | ENSG0000000065060.12 | 1.627e-11 | 0 | -37283 | gtex_brain_putamen_basal |
| rs7756405 | 6 | 34722659 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -37198 | gtex_brain_putamen_basal |
| RS9469859 | 6 | 34722902 | UHRF1BP1 | ENSG0000000065060.12 | 3.813E-11 | 0 | -36955 | gtex_brain_putamen_basal |
| RS28398813 | 6 | 34725658 | UHRF1BP1 | ENSG0000000065060.12 | 3.995E-7 | 0 | -34199 | gtex_brain_putamen_basal |
| RS59247079 | 6 | 34725658 | UHRF1BP1 | ENSG0000000065060.12 | 5.65E-12 | 0 | -34199 | gtex_brain_putamen_basal |
| RS9469861 | 6 | 34726136 | UHRF1BP1 | ENSG0000000065060.12 | 4.986E-11 | 0 | -33721 | gtex_brain_putamen_basal |
| RS13198620 | 6 | 34726361 | UHRF1BP1 | ENSG0000000065060.12 | 3.656e-11 | 0 | -33496 | gtex_brain_putamen_basal |
| RS7341253 | 6 | 34726838 | UHRF1BP1 | ENSG0000000065060.12 | 4.486e-11 | 0 | -33019 | gtex_brain_putamen_basal |
| rs7341267 | 6 | 34727031 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -32826 | gtex_brain_putamen_basal |
| rs7759227 | 6 | 34728230 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -31627 | gtex_brain_putamen_basal |
| RS7341329 | 6 | 34729162 | UHRF1BP1 | ENSG0000000065060.12 | 1.959E-11 | 0 | -30695 | gtex_brain_putamen_basal |
| RS9469862 | 6 | 34729848 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -30009 | gtex_brain_putamen_basal |
| rs11965761 | 6 | 34731225 | UHRF1BP1 | ENSG0000000065060.12 | 4.315E-10 | 0 | -28632 | gtex_brain_putamen_basal |
| RS148024643 | 6 | 34731649 | UHRF1BP1 | ENSG0000000065060.12 | 1.631E-7 | 0 | -28208 | gtex_brain_putamen_basal |
| RS137931729 | 6 | 34731686 | UHRF1BP1 | ENSG0000000065060.12 | 1.89E-10 | 0 | -28171 | gtex_brain_putamen_basal |
| RS7762644 | 6 | 34732145 | UHRF1BP1 | ENSG0000000065060.12 | 2.922e-11 | 0 | -27712 | gtex_brain_putamen_basal |
| RS28675115 | 6 | 34732514 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -27343 | gtex_brain_putamen_basal |
| RS7739766 | 6 | 34733362 | UHRF1BP1 | ENSG0000000065060.12 | 7.601E-11 | 0 | -26495 | gtex_brain_putamen_basal |
| RS7763224 | 6 | 34734239 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -25618 | gtex_brain_putamen_basal |
| RS3798352 | 6 | 34734809 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -25048 | gtex_brain_putamen_basal |
| RS6940395 | 6 | 34736553 | UHRF1BP1 | ENSG0000000065060.12 | 1.058E-10 | 0 | -23304 | gtex_brain_putamen_basal |
| RS7741437 | 6 | 34737553 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -22304 | gtex_brain_putamen_basal |
| rs2038841 | 6 | 34738203 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -21654 | gtex_brain_putamen_basal |
| RS9469863 | 6 | 34739649 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -20208 | gtex_brain_putamen_basal |
| rs9462015 | 6 | 34739726 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -20131 | gtex_brain_putamen_basal |
| RS9394248 | 6 | 34739875 | UHRF1BP1 | ENSG0000000065060.12 | 2.325e-10 | 0 | -19982 | gtex_brain_putamen_basal |
| RS35597448 | 6 | 34741700 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -18157 | gtex_brain_putamen_basal |
| RS1998702 | 6 | 34741917 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -17940 | gtex_brain_putamen_basal |
| RS9469866 | 6 | 34742248 | UHRF1BP1 | ENSG0000000065060.12 | 1.927E-11 | 0 | -17609 | gtex_brain_putamen_basal |
| RS9469867 | 6 | 34742449 | UHRF1BP1 | ENSG0000000065060.12 | 2.131 e-11 | 0 | -17408 | gtex_brain_putamen_basal |
| RS7768189 | 6 | 34742450 | UHRF1BP1 | ENSG0000000065060.12 | 6.364e-12 | 0 | -17407 | gtex_brain_putamen_basal |
| RS6906759 | 6 | 34742990 | UHRF1BP1 | ENSG0000000065060.12 | 1.835E-11 | 0 | -16867 | gtex_brain_putamen_basal |
| RS375038003 | 6 | 34743432 | UHRF1BP1 | ENSG0000000065060.12 | 4.955e-11 | 0 | -16425 | gtex_brain_putamen_basal |
| rs398094094 | 6 | 34743617 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -16240 | gtex_brain_putamen_basal |
| RS144904389 | 6 | 34743865 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -15992 | gtex_brain_putamen_basal |
| rs71000097 | 6 | 34743866 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -15991 | gtex_brain_putamen_basal |
| RS9469868 | 6 | 34744014 | UHRF1BP1 | ENSG0000000065060.12 | 1.021E-9 | 0 | -15843 | gtex_brain_putamen_basal |
| RS9469869 | 6 | 34744134 | UHRF1BP1 | ENSG0000000065060.12 | 5.801E-11 | 0 | -15723 | gtex_brain_putamen_basal |
| RS9469870 | 6 | 34744349 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -15508 | gtex_brain_putamen_basal |
| RS9469871 | 6 | 34745007 | UHRF1BP1 | ENSG0000000065060.12 | 1.78e-11 | 0 | -14850 | gtex_brain_putamen_basal |
| RS9296128 | 6 | 34745682 | UHRF1BP1 | ENSG0000000065060.12 | 1.294E-10 | 0 | -14175 | gtex_brain_putamen_basal |
| RS9469872 | 6 | 34745703 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -14154 | gtex_brain_putamen_basal |
| rs2038840 | 6 | 34746151 | UHRF1BP1 | ENSG0000000065060.12 | 2.121E-10 | 0 | -13706 | gtex_brain_putamen_basal |
| RS11759151 | 6 | 34747603 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -12254 | gtex_brain_putamen_basal |
| rs9462018 | 6 | 34748728 | UHRF1BP1 | ENSG0000000065060.12 | 9.872e-11 | 0 | -11129 | gtex_brain_putamen_basal |
| rs9462019 | 6 | 34748730 | UHRF1BP1 | ENSG0000000065060.12 | 1.16e-10 | 0 | -11127 | gtex_brain_putamen_basal |
| rs35285078 | 6 | 34748893 | UHRF1BP1 | ENSG0000000065060.12 | 2.443E-7 | 0 | -10964 | gtex_brain_putamen_basal |
| RS6900188 | 6 | 34749008 | UHRF1BP1 | ENSG0000000065060.12 | 5.917E-10 | 0 | -10849 | gtex_brain_putamen_basal |
| rs6899938 | 6 | 34749113 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -10744 | gtex_brain_putamen_basal |
| rs6900847 | 6 | 34749532 | UHRF1BP1 | ENSG0000000065060.12 | 3.807E-11 | 0 | -10325 | gtex_brain_putamen_basal |
| rs9689160 | 6 | 34749849 | UHRF1BP1 | ENSG0000000065060.12 | 3.543E-7 | 0 | -10008 | gtex_brain_putamen_basal |
| rs6930036 | 6 | 34750728 | UHRF1BP1 | ENSG0000000065060.12 | 2.9E-10 | 0 | -9129 | gtex_brain_putamen_basal |
| rs9462020 | 6 | 34751265 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -8592 | gtex_brain_putamen_basal |
| RS58843872 | 6 | 34752010 | UHRF1BP1 | ENSG0000000065060.12 | 7.667e-11 | 0 | -7847 | gtex_brain_putamen_basal |
| RS58671447 | 6 | 34752351 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -7506 | gtex_brain_putamen_basal |
| RS9689516 | 6 | 34752678 | UHRF1BP1 | ENSG0000000065060.12 | 8.598E-11 | 0 | -7179 | gtex_brain_putamen_basal |
| rs9689820 | 6 | 34752963 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -6894 | gtex_brain_putamen_basal |
| rs112782669 | 6 | 34753274 | UHRF1BP1 | ENSG0000000065060.12 | 3.543E-7 | 0 | -6583 | gtex_brain_putamen_basal |
| rs200893385 | 6 | 34753277 | UHRF1BP1 | ENSG0000000065060.12 | 3.543E-7 | 0 | -6580 | gtex_brain_putamen_basal |
| rs34493158 | 6 | 34753339 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | -6518 | gtex_brain_putamen_basal |
| RS191486015 | 6 | 34754141 | UHRF1BP1 | ENSG0000000065060.12 | 9.186e-7 | 0 | -5716 | gtex_brain_putamen_basal |
| RS9469878 | 6 | 34756761 | UHRF1BP1 | ENSG0000000065060.12 | 1.888e-9 | 0 | -3096 | gtex_brain_putamen_basal |
| RS9469879 | 6 | 34756909 | UHRF1BP1 | ENSG0000000065060.12 | 8.43e-10 | 0 | -2948 | gtex_brain_putamen_basal |
| RS9469880 | 6 | 34757256 | UHRF1BP1 | ENSG0000000065060.12 | 1.276E-9 | 0 | -2601 | gtex_brain_putamen_basal |
| RS9469882 | 6 | 34757810 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -2047 | gtex_brain_putamen_basal |
| RS9469883 | 6 | 34758627 | UHRF1BP1 | ENSG0000000065060.12 | 5.058e-11 | 0 | -1230 | gtex_brain_putamen_basal |
| rs9462021 | 6 | 34758640 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -1217 | gtex_brain_putamen_basal |
| RS9469884 | 6 | 34758703 | UHRF1BP1 | ENSG0000000065060.12 | 6.051e-11 | 0 | -1154 | gtex_brain_putamen_basal |
| RS9469885 | 6 | 34758716 | UHRF1BP1 | ENSG0000000065060.12 | 1.803e-11 | 0 | -1141 | gtex_brain_putamen_basal |
| RS9469886 | 6 | 34758824 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | -1033 | gtex_brain_putamen_basal |
| RS9469887 | 6 | 34758940 | UHRF1BP1 | ENSG0000000065060.12 | 3.014e-11 | 0 | -917 | gtex_brain_putamen_basal |
| rs13215181 | 6 | 34759881 | UHRF1BP1 | ENSG0000000065060.12 | 1.937E-10 | 0 | 24 | gtex_brain_putamen_basal |
| rs6934662 | 6 | 34759884 | UHRF1BP1 | ENSG0000000065060.12 | 1.731e-11 | 0 | 27 | gtex_brain_putamen_basal |
| RS6457791 | 6 | 34759954 | UHRF1BP1 | ENSG0000000065060.12 | 1.166E-8 | 0 | 97 | gtex_brain_putamen_basal |
| rs7769961 | 6 | 34760162 | UHRF1BP1 | ENSG0000000065060.12 | 5.986e-11 | 0 | 305 | gtex_brain_putamen_basal |
| RS7769820 | 6 | 34760228 | UHRF1BP1 | ENSG0000000065060.12 | 1.238E-11 | 0 | 371 | gtex_brain_putamen_basal |
| rs7752060 | 6 | 34760325 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 468 | gtex_brain_putamen_basal |
| RS7752522 | 6 | 34760583 | UHRF1BP1 | ENSG0000000065060.12 | 4.553e-12 | 0 | 726 | gtex_brain_putamen_basal |
| RS11757370 | 6 | 34760736 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 879 | gtex_brain_putamen_basal |
| rs11755420 | 6 | 34760956 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 1099 | gtex_brain_putamen_basal |
| rs9462022 | 6 | 34761684 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 1827年 | gtex_brain_putamen_basal |
| rs6942040 | 6 | 34761809 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 1952 | gtex_brain_putamen_basal |
| RS71686659 | 6 | 34762004 | UHRF1BP1 | ENSG0000000065060.12 | 5.655e-11 | 0 | 2147 | gtex_brain_putamen_basal |
| RS9469889 | 6 | 34763900 | UHRF1BP1 | ENSG0000000065060.12 | 5.383e-11 | 0 | 4043 | gtex_brain_putamen_basal |
| RS6457792 | 6 | 34764443 | UHRF1BP1 | ENSG0000000065060.12 | 3.011E-7 | 0 | 4586 | gtex_brain_putamen_basal |
| RS6912327 | 6 | 34764922 | UHRF1BP1 | ENSG0000000065060.12 | 4.096E-7 | 0 | 5065 | gtex_brain_putamen_basal |
| RS10947531 | 6 | 34765118 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 5261 | gtex_brain_putamen_basal |
| RS998278 | 6 | 34765584 | UHRF1BP1 | ENSG0000000065060.12 | 4.55e-12 | 0 | 5727 | gtex_brain_putamen_basal |
| RS9469891 | 6 | 34767396 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 7539 | gtex_brain_putamen_basal |
| RS9469892 | 6 | 34769101 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 9244 | gtex_brain_putamen_basal |
| rs9462023 | 6 | 34769410 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 9553 | gtex_brain_putamen_basal |
| RS9469893 | 6 | 34769580 | UHRF1BP1 | ENSG0000000065060.12 | 5.732E-11 | 0 | 9723 | gtex_brain_putamen_basal |
| RS7756949 | 6 | 34770181 | UHRF1BP1 | ENSG0000000065060.12 | 7.886e-12 | 0 | 10324 | gtex_brain_putamen_basal |
| rs6921363 | 6 | 34770820 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 10963 | gtex_brain_putamen_basal |
| RS3798348 | 6 | 34771892 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 12035 | gtex_brain_putamen_basal |
| RS3777752 | 6 | 34772212 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 12355 | gtex_brain_putamen_basal |
| rs9462024 | 6 | 34772793 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 12936 | gtex_brain_putamen_basal |
| RS9296129 | 6 | 34774414 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 14557 | gtex_brain_putamen_basal |
| RS9469894 | 6 | 34774725 | UHRF1BP1 | ENSG0000000065060.12 | 8.1e-11 | 0 | 14868 | gtex_brain_putamen_basal |
| RS9296131 | 6 | 34776361 | UHRF1BP1 | ENSG0000000065060.12 | 1.802e-11 | 0 | 16504 | gtex_brain_putamen_basal |
| RS6905393 | 6 | 34776626 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 16769 | gtex_brain_putamen_basal |
| RS4601124 | 6 | 34776910 | UHRF1BP1 | ENSG0000000065060.12 | 5.658e-11 | 0 | 17053 | gtex_brain_putamen_basal |
| rs34141614 | 6 | 34777031 | UHRF1BP1 | ENSG0000000065060.12 | 6.913e-11 | 0 | 17174 | gtex_brain_putamen_basal |
| rs66506671 | 6 | 34777149 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 17292 | gtex_brain_putamen_basal |
| RS9296132 | 6 | 34777531 | UHRF1BP1 | ENSG0000000065060.12 | 1.624e-11 | 0 | 17674 | gtex_brain_putamen_basal |
| RS9296133 | 6 | 34777533 | UHRF1BP1 | ENSG0000000065060.12 | 3.515E-7 | 0 | 17676 | gtex_brain_putamen_basal |
| rs2038839 | 6 | 34777791 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 17934 | gtex_brain_putamen_basal |
| rs2395606 | 6 | 34778486 | UHRF1BP1 | ENSG0000000065060.12 | 1.37E-11 | 0 | 18629 | gtex_brain_putamen_basal |
| RS7739771 | 6 | 34779801 | UHRF1BP1 | ENSG0000000065060.12 | 5.697e-11 | 0 | 19944 | gtex_brain_putamen_basal |
| RS10947532 | 6 | 34780315 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 20458 | gtex_brain_putamen_basal |
| rs58338619 | 6 | 34782201 | UHRF1BP1 | ENSG0000000065060.12 | 3.513E-7 | 0 | 22344 | gtex_brain_putamen_basal |
| RS1543559 | 6 | 34784104 | UHRF1BP1 | ENSG0000000065060.12 | 4.279e-11 | 0 | 24247 | gtex_brain_putamen_basal |
| RS56924792 | 6 | 34784165 | UHRF1BP1 | ENSG0000000065060.12 | 5.269e-12 | 0 | 24308 | gtex_brain_putamen_basal |
| rs59111782 | 6 | 34784292 | UHRF1BP1 | ENSG0000000065060.12 | 3.598E-11 | 0 | 24435 | gtex_brain_putamen_basal |
| RS1543558 | 6 | 34784371 | UHRF1BP1 | ENSG0000000065060.12 | 1.628E-11 | 0 | 24514 | gtex_brain_putamen_basal |
| rs7776219 | 6 | 34784667 | UHRF1BP1 | ENSG0000000065060.12 | 6.22e-11 | 0 | 24810 | gtex_brain_putamen_basal |
| RS1125341 | 6 | 34786305 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 26448 | gtex_brain_putamen_basal |
| RS1125340 | 6 | 34786408 | UHRF1BP1 | ENSG0000000065060.12 | 5.737e-11 | 0 | 26551 | gtex_brain_putamen_basal |
| rs2395604 | 6 | 34787976 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 28119 | gtex_brain_putamen_basal |
| RS1886574 | 6 | 34788612 | UHRF1BP1 | ENSG0000000065060.12 | 8.548e-11 | 0 | 28755 | gtex_brain_putamen_basal |
| RS7752390 | 6 | 34790624 | UHRF1BP1 | ENSG0000000065060.12 | 1.695e-12 | 0 | 30767 | gtex_brain_putamen_basal |
| rs7774697 | 6 | 34791027 | UHRF1BP1 | ENSG0000000065060.12 | 5.654e-11 | 0 | 31170 | gtex_brain_putamen_basal |
| RS112732340 | 6 | 34791333 | UHRF1BP1 | ENSG0000000065060.12 | 1.844E-11 | 0 | 31476 | gtex_brain_putamen_basal |
| rs6941110 | 6 | 34791334 | UHRF1BP1 | ENSG0000000065060.12 | 1.487E-11 | 0 | 31477 | gtex_brain_putamen_basal |
| RS12177835 | 6 | 34792262 | UHRF1BP1 | ENSG0000000065060.12 | 1.845E-10 | 0 | 32405 | gtex_brain_putamen_basal |
| RS9469899 | 6 | 34793124 | UHRF1BP1 | ENSG0000000065060.12 | 1.016E-8 | 0 | 33267 | gtex_brain_putamen_basal |
| rs9469902 | 6 | 34793768 | UHRF1BP1 | ENSG0000000065060.12 | 5.665E-11 | 0 | 33911 | gtex_brain_putamen_basal |
| rs144022875 | 6 | 34793804 | UHRF1BP1 | ENSG0000000065060.12 | 1.322E-9 | 0 | 33947 | gtex_brain_putamen_basal |
| rs7745097 | 6 | 34794434 | UHRF1BP1 | ENSG0000000065060.12 | 1.626e-11 | 0 | 34577 | gtex_brain_putamen_basal |
| rs11754574 | 6 | 34794961 | UHRF1BP1 | ENSG0000000065060.12 | 5.105e-10 | 0 | 35104 | gtex_brain_putamen_basal |
| RS7768759 | 6 | 34795685 | UHRF1BP1 | ENSG0000000065060.12 | 1.626e-11 | 0 | 35828 | gtex_brain_putamen_basal |
| rs9469904 | 6 | 34796084 | UHRF1BP1 | ENSG0000000065060.12 | 3.513E-7 | 0 | 36227 | gtex_brain_putamen_basal |
| rs13219589 | 6 | 34796783 | UHRF1BP1 | ENSG0000000065060.12 | 1.486E-9 | 0 | 36926 | gtex_brain_putamen_basal |
| rs9462026 | 6 | 34797033 | UHRF1BP1 | ENSG0000000065060.12 | 5.665E-11 | 0 | 37176 | gtex_brain_putamen_basal |
| rs9462027 | 6 | 34797241 | UHRF1BP1 | ENSG0000000065060.12 | 3.513E-7 | 0 | 37384 | gtex_brain_putamen_basal |
| rs9469905 | 6 | 34797747 | UHRF1BP1 | ENSG0000000065060.12 | 3.065e-11 | 0 | 37890 | gtex_brain_putamen_basal |
| RS112283401 | 6 | 34797756 | UHRF1BP1 | ENSG0000000065060.12 | 1.885E-10 | 0 | 37899 | gtex_brain_putamen_basal |
| RS112327514 | 6 | 34798098 | UHRF1BP1 | ENSG0000000065060.12 | 5.665E-11 | 0 | 38241 | gtex_brain_putamen_basal |
| rs9462028 | 6 | 34798265 | UHRF1BP1 | ENSG0000000065060.12 | 1.261E-10 | 0 | 38408 | gtex_brain_putamen_basal |
| RS6457794 | 6 | 34799130 | UHRF1BP1 | ENSG0000000065060.12 | 1.413E-9 | 0 | 39273 | gtex_brain_putamen_basal |
| rs6937132 | 6 | 34799221 | UHRF1BP1 | ENSG0000000065060.12 | 5.655e-11 | 0 | 39364 | gtex_brain_putamen_basal |
| RS6937314 | 6 | 34799308 | UHRF1BP1 | ENSG0000000065060.12 | 5.664e-11 | 0 | 39451 | gtex_brain_putamen_basal |
| RS7739003 | 6 | 34800329 | UHRF1BP1 | ENSG0000000065060.12 | 3.651e-11 | 0 | 40472 | gtex_brain_putamen_basal |
| RS6925623 | 6 | 34800896 | UHRF1BP1 | ENSG0000000065060.12 | 5.664e-11 | 0 | 41039 | gtex_brain_putamen_basal |
| rs6906129 | 6 | 34801160 | UHRF1BP1 | ENSG0000000065060.12 | 1.626e-11 | 0 | 41303 | gtex_brain_putamen_basal |
| rs34657938 | 6 | 34801631 | UHRF1BP1 | ENSG0000000065060.12 | 2.858E-10 | 0 | 41774 | gtex_brain_putamen_basal |
| RS4624858 | 6 | 34802301 | UHRF1BP1 | ENSG0000000065060.12 | 5.664e-11 | 0 | 42444 | gtex_brain_putamen_basal |
| rs2296360 | 6 | 34803558 | UHRF1BP1 | ENSG0000000065060.12 | 5.662e-11 | 0 | 43701 | gtex_brain_putamen_basal |
| rs4259246 | 6 | 34803947 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 44090 | gtex_brain_putamen_basal |
| RS72363955 | 6 | 34807115 | UHRF1BP1 | ENSG0000000065060.12 | 1.573E-9 | 0 | 47258 | gtex_brain_putamen_basal |
| RS13220394 | 6 | 34810172 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 50315 | gtex_brain_putamen_basal |
| RS6919654 | 6 | 34810739 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 50882 | gtex_brain_putamen_basal |
| rs6924898 | 6 | 34811199 | UHRF1BP1 | ENSG0000000065060.12 | 2.004e-11 | 0 | 51342 | gtex_brain_putamen_basal |
| RS200628567 | 6 | 34811688 | UHRF1BP1 | ENSG0000000065060.12 | 1.722e-11 | 0 | 51831 | gtex_brain_putamen_basal |
| RS36111695 | 6 | 34811689 | UHRF1BP1 | ENSG0000000065060.12 | 1.722e-11 | 0 | 51832 | gtex_brain_putamen_basal |
| RS7748203 | 6 | 34812054 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 52197 | gtex_brain_putamen_basal |
| rs9469909 | 6 | 34813077 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 53220 | gtex_brain_putamen_basal |
| RS6457795 | 6 | 34819366 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 59509 | gtex_brain_putamen_basal |
| rs35964461 | 6 | 34820555 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 60698 | gtex_brain_putamen_basal |
| RS6939600 | 6 | 34822176 | UHRF1BP1 | ENSG0000000065060.12 | 1.762e-11 | 0 | 62319 | gtex_brain_putamen_basal |
| RS11755393 | 6 | 34824636 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 64779 | gtex_brain_putamen_basal |
| rs9469914 | 6 | 34827693 | UHRF1BP1 | ENSG0000000065060.12 | 5.838e-11 | 0 | 67836 | gtex_brain_putamen_basal |
| RS6457796 | 6 | 34828553 | UHRF1BP1 | ENSG0000000065060.12 | 1.043E-6 | 0 | 68696 | gtex_brain_putamen_basal |
| rs4282407 | 6 | 34830162 | UHRF1BP1 | ENSG0000000065060.12 | 1.409E-10 | 0 | 70305 | gtex_brain_putamen_basal |
| rs9462030 | 6 | 34831280 | UHRF1BP1 | ENSG0000000065060.12 | 5.598E-11 | 0 | 71423 | gtex_brain_putamen_basal |
| rs9469917 | 6 | 34831369 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 71512 | gtex_brain_putamen_basal |
| rs3734264 | 6 | 34831866 | UHRF1BP1 | ENSG0000000065060.12 | 1.623e-11 | 0 | 72009 | gtex_brain_putamen_basal |
| rs6925764 | 6 | 34832661 | UHRF1BP1 | ENSG0000000065060.12 | 1.339e-11 | 0 | 72804 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
基因ral gene expression (GTEx)
Devlopment期间的基因表达（BrainCloud）
脚注：
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。
时间变化的基因表达（brainspan）
脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。
大脑区域的顶级共表达基因
| Top 10 positively co-expressed genes | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| KLHL25 | 0.90 | 0.88 |
| vash1 | 0.89 | 0.89 |
| ZNF74 | 0.88 | 0.89 |
| TSKU | 0.87 | 0.86 |
| ankrd13b | 0.87 | 0.88 |
| PLXNB2 | 0.87 | 0.88 |
| CD276 | 0.87 | 0.89 |
| MTA1 | 0.87 | 0.89 |
| REC8 | 0.87 | 0.84 |
| ZSWIM4 | 0.87 | 0.88 |
| 前10个负共表达基因 | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| C5orf53 | -0.65 | -0.72 |
| AF347015.27 | -0.64 | -0.80 |
| AF347015.31 | -0.63 | -0.78 |
| HLA-F | -0.62 | -0.66 |
| S100B | -0.62 | -0.75 |
| MT-CO2 | -0.62 | -0.79 |
| AF347015.33 | -0.61 | -0.76 |
| ACOT13 | -0.60 | -0.66 |
| MT-CYB | -0.60 | -0.76 |
| AIFM3 | -0.60 | -0.63 |
V.途径注释
| 路径名 | Pathway size | ＃szgr 2.0基因 | Info |
|---|---|---|---|
| Senese HDAC3靶向DN | 536 | 332 | 该途径中的所有SZGR 2.0基因 |
| EWSR1 FLII融合的Kinsey目标 | 1278 | 748 | 该途径中的所有SZGR 2.0基因 |
| MCBRYAN PUBERTAL BREAST 3 4WK UP | 214 | 144 | 该途径中的所有SZGR 2.0基因 |
| McBryan Pubertal乳房4 5WK DN | 196 | 131 | 该途径中的所有SZGR 2.0基因 |
| McBryan Pubertal乳房5 6WK | 116 | 68 | 该途径中的所有SZGR 2.0基因 |
| McBryan Pubertal乳房6 7WK DN | 79 | 54 | 该途径中的所有SZGR 2.0基因 |
| Mir192和Mir215的Georges目标 | 893 | 528 | 该途径中的所有SZGR 2.0基因 |
| Creighton内分泌疗法抗性2 | 473 | 224 | 该途径中的所有SZGR 2.0基因 |
第六节。microRNA注释
| mirna家族 | 目标位置 | mirna id | miRNA seq | ||
|---|---|---|---|---|---|
| UTR start | UTR end | Match method | |||
| mir-138 | 41 | 48 | 1A，M8 | hsa-miR-138脑 | Agcugguuguguugaauc |
| miR-27 | 5033 | 5039 | 1a | HSA-MIR-27A脑 | UUCACAGUGGCUAAGUUCCGC |
| HSA-MIR-27B脑 | UUCACAGUGGCUAAGUUCUGC | ||||
| mir-30-3p | 5044 | 5050 | 1a | hsa-miR-30a-3p | cuuucagucggauguugcagc |
| hsa-miR-30e-3p | cuuucagucggauguauacagc | ||||
| mir-30-5p | 3614 | 3621 | 1A，M8 | hsa-miR-30a-5p | uguaaaacauccuccuggaag |
| HSA-MIR-30C脑 | uguaaacauccuacucucucucucagc | ||||
| HSA-MIR-30DSZ | uguaaacauccccgacuggaag | ||||
| HSA-MIR-30BSZ | UGUAAACAUCCUACACUCAGCU | ||||
| HSA-MIR-30E-5P | uguaaacauccuugacugga | ||||
| mir-378 | 4783 | 4789 | 1a | hsa-miR-378 | cuccugacuccaggucugugu |
| mir-499 | 4620 | 4627 | 1A，M8 | HSA-MIR-499 | uuaagacuugcagugauguuaa |
| mir-93.hd/291-3p/294/295/302/372/373/520 | 2631 | 2637 | M8 | hsa-miR-93脑 | AAAGUGCUGUUCGUGCAGGUAG |
| HSA-MIR-302A | UAAGUGCUUCCAUGUUUUGGUGA | ||||
| HSA-MIR-302B | UAAGUGCUUCCAUGUUUUAGUAG | ||||
| HSA-MIR-302C | UAAGUGCUUCCAUGUUUCAGUGG | ||||
| HSA-MIR-302D | UAAGUGCUUCCAUGUUUGAGUGU | ||||
| hsa-miR-372 | AAAGUGCUGCGACAUUUGAGCGU | ||||
| hsa-miR-373 | GAAGUGCUUCGAUUUUGGGGUGU | ||||
| HSA-MIR-520E | Aaagugcuuuuuugaggg | ||||
| HSA-MIR-520A | aaagugcuucccuuguggugu | ||||
| HSA-MIR-520B | AAAGUGCUUCCUUUUAGAGGG | ||||
| HSA-MIR-520C | AAAGUGCUUCCUUUUAGAGGGUU | ||||
| HSA-MIR-520D | AAAGUGCUUCUCUUUGGUGGGUU | ||||