Gene Page:PPP1R3A
Summary?
| GeneID | 5506 |
| Symbol | PPP1R3A |
| Synonyms | GM|PP1G|PPP1R3 |
| Description | protein phosphatase 1 regulatory subunit 3A |
| Reference | MIM:600917|HGNC:HGNC:9291|Ensembl:ENSG00000154415|HPRD:02950|Vega:OTTHUMG00000156944 |
| Gene type | protein-coding |
| Map location | 7q31.1 |
| Pascal p-value | 0.024 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PEX19 | 0.90 | 0.90 |
| GDE1 | 0.88 | 0.88 |
| GHITM | 0.86 | 0.89 |
| HCCS | 0.86 | 0.86 |
| MAT2B | 0.86 | 0.88 |
| ATG7 | 0.85 | 0.88 |
| TMX2 | 0.85 | 0.87 |
| PGK1 | 0.85 | 0.84 |
| PKM2 | 0.85 | 0.88 |
| ARL8B | 0.85 | 0.89 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AC010300.1 | -0.45 | -0.47 |
| AC005921.3 | -0.45 | -0.55 |
| AC135724.1 | -0.43 | -0.49 |
| RP9P | -0.42 | -0.46 |
| FAM159B | -0.41 | -0.47 |
| ZNF814 | -0.41 | -0.49 |
| IL3RA | -0.41 | -0.56 |
| AF347015.18 | -0.41 | -0.16 |
| AL022328.1 | -0.40 | -0.42 |
| C10orf108 | -0.38 | -0.35 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG INSULIN SIGNALING PATHWAY | 137 | 103 | All SZGR 2.0 genes in this pathway |
| PID INSULIN GLUCOSE PATHWAY | 26 | 24 | All SZGR 2.0 genes in this pathway |
| MULLIGHAN NPM1 SIGNATURE 3 UP | 341 | 197 | All SZGR 2.0 genes in this pathway |
| SWEET KRAS TARGETS DN | 66 | 39 | All SZGR 2.0 genes in this pathway |
| KAAB HEART ATRIUM VS VENTRICLE DN | 261 | 183 | All SZGR 2.0 genes in this pathway |
| XU GH1 EXOGENOUS TARGETS DN | 120 | 69 | All SZGR 2.0 genes in this pathway |
| MOOTHA GLYCOGEN METABOLISM | 21 | 16 | All SZGR 2.0 genes in this pathway |
| PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |