Gene Page:PPP6R3

Summary?
GeneID 55291
Symbol PPP6R3
Synonyms C11orf23|PP6R3|SAP190|SAPL|SAPLa|SAPS3
Description protein phosphatase 6 regulatory subunit 3
Reference MIM:610879|HGNC:HGNC:1173|Ensembl:ENSG00000110075|HPRD:10703|Vega:OTTHUMG00000167596
Gene type protein-coding
Map location 11q13
Pascal p-value 0.003
Sherlock p-value 0.824
Fetal beta 0.584
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs16829545 chr2 151977407 PPP6R3 55291 0.18 trans
rs16894557 chr6 28999825 PPP6R3 55291 0.09 trans
rs7020639 chr9 71907868 PPP6R3 55291 0.11 trans
rs16955618 chr15 29937543 PPP6R3 55291 0.12 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
WANG CLIM2 TARGETS UP 269 146 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED DN 805 505 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN UP 1142 669 All SZGR 2.0 genes in this pathway
MCBRYAN发育期的BREAST 4 5WK DN 196 131 All SZGR 2.0 genes in this pathway
MCBRYAN发育期的BREAST 5 6WK DN 137 97 All SZGR 2.0 genes in this pathway
MCBRYAN发育期的BREAST 6 7WK UP 197 135 All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648 385 All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 11Q12 Q14 AMPLICON 158 93 All SZGR 2.0 genes in this pathway
KENNY CTNNB1 TARGETS DN 52 34 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 473 224 All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA CHEMOTAXIS DN 457 302 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE M G1 148 95 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504 321 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE LATE 1137 655 All SZGR 2.0 genes in this pathway