Gene Page:ZFP64

Summary?
GeneID 55734
Symbol ZFP64
Synonyms ZNF338
Description ZFP64 zinc finger protein
Reference HGNC:HGNC:15940|Ensembl:ENSG00000020256|HPRD:15728|Vega:OTTHUMG00000032756
Gene type protein-coding
Map location 20q13.2
Pascal p-value 0.022
Sherlock p-value 0.908
Fetal beta 0.473
DMG 2 (# studies)
eGene Myers' cis & trans
元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Jaffe_2016 Genome-wide DNA methylation analysis This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 3
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 3

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg07604202 20 50701378 ZFP64 1.55E-5 0.33 0.015 DMG:Wockner_2014
cg26929161 20 50701266 ZFP64 1.66E-5 0.481 0.015 DMG:Wockner_2014
cg00586889 20 50807767 ZFP64 3.13E-8 -0.022 9.51E-6 DMG:Jaffe_2016

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs6021571 chr20 50574626 ZFP64 55734 0.2 cis

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),圣2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
NFE2L1 0.92 0.90
SRPR 0.88 0.86
PRKACA 0.87 0.84
HYOU1 0.87 0.83
MAGEE1 0.86 0.84
PI4K2A 0.86 0.83
CDS2 0.86 0.84
ADARB1 0.86 0.84
SYT11 0.85 0.87
APLP2 0.85 0.82
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.21 -0.59 -0.49
GNG11 -0.53 -0.48
C1orf54 -0.53 -0.51
AL050337.1 -0.51 -0.48
IL32 -0.51 -0.48
C1orf61 -0.50 -0.48
SYCP3 -0.49 -0.48
VAMP5 -0.48 -0.43
AF347015.31 -0.48 -0.43
FAM159B -0.48 -0.53

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ZHOU INFLAMMATORY RESPONSE LIVE DN 384 220 All SZGR 2.0 genes in this pathway
BILBAN B CLL LPL UP 63 39 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS DN 459 276 All SZGR 2.0 genes in this pathway
VANHARANTA UTERINE FIBROID WITH 7Q DELETION UP 67 37 All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 20Q12 Q13 AMPLICON 149 76 All SZGR 2.0 genes in this pathway
NIKOLSKY MUTATED AND AMPLIFIED IN BREAST CANCER 94 60 All SZGR 2.0 genes in this pathway
LIN MELANOMA COPY NUMBER UP 73 53 All SZGR 2.0 genes in this pathway
MITSIADES RESPONSE TO APLIDIN DN 249 165 All SZGR 2.0 genes in this pathway
GUTIERREZ CHRONIC LYMPHOCYTIC LEUKEMIA DN 56 39 All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE MIDDLE 98 56 All SZGR 2.0 genes in this pathway
DELACROIX RAR BOUND ES 462 273 All SZGR 2.0 genes in this pathway
RAO BOUND BY SALL4 ISOFORM B 517 302 All SZGR 2.0 genes in this pathway