Gene Page:CCAR1
Summary?
| GeneID | 55749 |
| Symbol | CCAR1 |
| Synonyms | - |
| Description | cell division cycle and apoptosis regulator 1 |
| Reference | MIM:612569|HGNC:HGNC:24236|Ensembl:ENSG00000060339|HPRD:10811|Vega:OTTHUMG00000018361 |
| Gene type | protein-coding |
| Map location | 10q21.3 |
| Pascal p-value | 0.008 |
| Sherlock p-value | 0.119 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs1257190 | chr2 | 135001594 | CCAR1 | 55749 | 0.09 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PPP2R5D | 0.90 | 0.88 |
| ACAD8 | 0.90 | 0.88 |
| BSDC1 | 0.89 | 0.86 |
| L3MBTL2 | 0.89 | 0.86 |
| MARS | 0.89 | 0.85 |
| MAEA | 0.88 | 0.86 |
| AAMP | 0.88 | 0.85 |
| CARKD | 0.88 | 0.85 |
| CLPTM1L | 0.88 | 0.85 |
| PSMD2 | 0.87 | 0.85 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.80 | -0.77 |
| AF347015.31 | -0.79 | -0.76 |
| MT-CO2 | -0.79 | -0.74 |
| AF347015.8 | -0.79 | -0.75 |
| AF347015.27 | -0.77 | -0.76 |
| MT-CYB | -0.76 | -0.73 |
| AF347015.33 | -0.76 | -0.73 |
| AF347015.2 | -0.76 | -0.70 |
| AF347015.15 | -0.74 | -0.72 |
| AF347015.26 | -0.72 | -0.68 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA | 140 | 77 | All SZGR 2.0 genes in this pathway |
| REACTOME MRNA PROCESSING | 161 | 86 | All SZGR 2.0 genes in this pathway |
| REACTOME MRNA SPLICING | 111 | 58 | All SZGR 2.0 genes in this pathway |
| GARY CD5 TARGETS DN | 431 | 263 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| GAUSSMANN MLL AF4 FUSION TARGETS C UP | 170 | 114 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES 1 | 379 | 235 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL | 254 | 164 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| 瑞士POSTRADIATION肿瘤逃避UP | 393 | 244 | All SZGR 2.0 genes in this pathway |
| ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR UP | 174 | 96 | All SZGR 2.0 genes in this pathway |
| ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN | 274 | 165 | All SZGR 2.0 genes in this pathway |
| KAMMINGA SENESCENCE | 41 | 26 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 DN | 918 | 550 | All SZGR 2.0 genes in this pathway |