Gene Page:MAPK1
Summary?
基因 | 5594 |
Symbol | MAPK1 |
Synonyms | ERK|ERK-2|ERK2|ERT1|MAPK2|P42MAPK|PRKM1|PRKM2|p38|p40|p41|p41mapk|p42-MAPK |
Description | 有丝分裂原激活的蛋白激酶1 |
Reference | MIM:176948|HGNC:HGNC:6871|Ensembl:ENSG00000100030|HPRD:01496|Vega:OTTHUMG00000030508 |
Gene type | 蛋白质编码 |
Map location | 22q11.21 |
Pascal p-value | 0.002 |
Sherlock p-value | 0.481 |
胎儿β | -1.658 |
主持人 | Myers' cis & trans |
Support | CANABINOID INTRACELLULAR SIGNAL TRANSDUCTION METABOTROPIC GLUTAMATE RECEPTOR 5-羟色胺 G2CDB.HUMAN_BAYES-COLLINS-HUMAN-PSD-FULL G2Cdb.human_BAYES-COLLINS-MOUSE-PSD-CONSENSUS G2Cdb.human_TAP-PSD-95-CORE G2CDB.HUMANNRC G2Cdb.humanPSD G2Cdb.humanPSP CompositeSet Darnell FMRP targets Potential synaptic genes |
Gene in Data Sources
Gene set name | Method of gene set | Description | 信息 |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
PMID:cooccur | High-throughput literature-search | Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included. | |
GSMA_I | Genome scan meta-analysis | Psr: 0.031 | |
Literature | High-throughput literature-search | Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenias | 点击显示详细信息 |
GO_Annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 1 | |
Network | Shortest path distance of core genes in the Human protein-protein interaction network | Contribution to shortest path in PPI network: 0.1451 |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | 主持人 | Gene Entrez ID | pvalue | QVALUE | TSS距离 | EQTL类型 |
---|---|---|---|---|---|---|---|---|
rs10504300 | chr8 | 60714730 | MAPK1 | 5594 | 0.12 | trans | ||
RS493713 | chr8 | 60882998 | MAPK1 | 5594 | 0.16 | trans |
第二节。转录组注释
一般基因表达(GTEX)
Gene expression during devlopment (BrainCloud)
Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
第三节。基因本体论注释
分子功能 | 去学期 | 证据 | 神经关键字 | PubMed ID |
---|---|---|---|---|
GO:0000166 | nucleotide binding | IEA | - | |
GO:0004707 | MAP激酶活性 | TAS | 10706854 | |
GO:0001784 | 磷酸酪氨酸结合 | IEA | - | |
去:0005515 | 蛋白质结合 | IPI | 9632734|16286470|16291755 |
|
去:0005524 | ATP binding | IEA | - | |
去:0004674 | protein serine/threonine kinase activity | EXP | 16626623 | |
去:0004674 | protein serine/threonine kinase activity | IEA | - | |
GO:0016740 | 转移酶活性 | IEA | - | |
生物过程 | 去学期 | 证据 | 神经关键字 | PubMed ID |
GO:0007268 | synaptic transmission | TAS | 神经元,突触,神经递质(GO期限:6) | 10051431 |
GO:0000165 | MAPKKK cascade | IEA | - | |
去:0006468 | protein amino acid phosphorylation | IEA | - | |
GO:0007265 | Ras protein signal transduction | EXP | 11520933 | |
GO:0006917 | 诱导凋亡 | TAS | 10958679 | |
GO:0009887 | organ morphogenesis | IEA | - | |
GO:0007049 | cell cycle | IEA | - | |
GO:0019858 | 胞嘧啶代谢过程 | IEA | - | |
GO:0006974 | response to DNA damage stimulus | IEA | - | |
GO:0006935 | chemotaxis | TAS | 10706854 | |
GO:0032496 | 对脂多糖的反应 | IEA | - | |
GO:0031663 | lipopolysaccharide-mediated signaling pathway | IEA | - | |
GO:0043330 | response to exogenous dsRNA | IEA | - | |
GO:0044419 | interspecies interaction between organisms | IEA | - | |
GO:0045596 | negative regulation of cell differentiation | IEA | - | |
Cellular component | 去学期 | 证据 | 神经关键字 | PubMed ID |
GO:0005829 | cytosol | EXP | 10066798|10878576 | |
GO:0005856 | 细胞骨架 | IDA | 18029348 | |
GO:0005634 | nucleus | IEA | - | |
GO:0005654 | nucleoplasm | EXP | 9687510|16456541|16626623 |17322878 |
|
去:0005730 | nucleolus | IDA | 18029348 | |
去:0005737 | cytoplasm | IEA | - |
Section IV. Protein-protein interaction annotation
Interactors | Aliases B | Official full name B | 实验 | Source | PubMed ID |
---|---|---|---|---|---|
ADAM17 | CD156b | MGC71942 | TACE | cSVP | ADAM metallopeptidase domain 17 | 亲和力捕获 - 韦斯特恩 生化活动 重构的复合物 |
Biogrid | 12058067 |
ar | AIS | DHTR | HUMARA | KD | NR3C4 | SBMA | SMAX1 | TFM | 雄激素受体 | 重构的复合物 | Biogrid | 10318905 |
ATF2 | CRE-BP1 | CREB2 | HB16 | MGC111558 | TREB7 | activating transcription factor 2 | 生化活动 | Biogrid | 7737129 |
ATP1A1 | MGC3285 | MGC51750 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 生化活动 | Biogrid | 15069082 |
BCL2 | Bcl-2 | B-cell CLL/lymphoma 2 | - | HPRD | 15225643 |
C1QBP | GC1QBP | HABP1 | SF2p32 | gC1Q-R | gC1qR | p32 | complement component 1, q subcomponent binding protein | - | HPRD,BioGRID | 11866440 |
CALCOCO1 | Cocoa | KIAA1536 | PP13275 | calphoglin | calcium binding and coiled-coil domain 1 | KIAA1536 is phosphorylated by MAPK1. This interaction was modeled on a demonstrated interaction between human KIAA1536 and MAPK1 from an unspecified species. | BIND | 15489336 |
CASP9 | APAF-3 | APAF3 | CASPASE-9c | ICE-LAP6 | MCH6 | caspase 9, apoptosis-related cysteine peptidase | - | HPRD,BioGRID | 12792650 |
CEBPB | C/EBP-beta | CRP2 | IL6DBP | LAP | MGC32080 | NF-IL6 | TCF5 | CCAAT/enhancer binding protein (C/EBP), beta | 生化活动 | Biogrid | 11500490 |
DAPK1 | DAPK | DKFZp781I035 | death-associated protein kinase 1 | DAPK interacts with Erk2. | BIND | 15616583 |
DUSP1 | CL100 | HVH1 | MKP-1 | MKP1 | PTPN10 | 双重特异性磷酸酶1 | - | HPRD,BioGRID | 11278799 |
DUSP16 | KIAA1700 | MGC129701 | MGC129702 | MKP-7 | MKP7 | 双重特异性磷酸酶16 | - | HPRD,BioGRID | 11489891 |
DUSP22 | JKAP | JSP1 | MKPX | VHX | dual specificity phosphatase 22 | 亲和力捕获 - 韦斯特恩 生化活动 |
Biogrid | 11346645 |
dusp3 | VHR | 双重特异性磷酸酶3 | - | HPRD,BioGRID | 10224087 |
DUSP4 | HVH2 | MKP-2 | MKP2 | TYP | 双重特异性磷酸酶4 | - | HPRD | 7535768 |
DUSP6 | MKP3 | PYST1 | 双重特异性磷酸酶6 | - | HPRD,BioGRID | 9535927 |
DUSP6 | MKP3 | PYST1 | 双重特异性磷酸酶6 | - | HPRD | 9535927|15269220 |
DYRK1B | MIRK | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B | - | HPRD,BioGRID | 10910078 |
ELK1 | - | ELK1, member of ETS oncogene family | Mapk1 phosphory (p42Mapk)lates Elk1 at Ser383. | BIND | 15782123 |
ELK1 | - | ELK1, member of ETS oncogene family | - | HPRD | 8208531|8586671 |
ELK1 | - | ELK1, member of ETS oncogene family | 生化活动 重构的复合物 |
Biogrid | 8586671|12594221 |
EPOR | MGC138358 | erythropoietin receptor | - | HPRD | 12538595 |
ESR1 | DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 | estrogen receptor 1 | - | HPRD,BioGRID | 12093745 |
FHL2 | AAG11 |Dral |Slim3 | four and a half LIM domains 2 | 亲和力捕获 - 韦斯特恩 重构的复合物 Two-hybrid |
Biogrid | 14729955 |
FHL3 | MGC19547 | MGC23614 | MGC8696 | SLIM2 | four and a half LIM domains 3 | - | HPRD | 14729955 |
GATA4 | MGC126629 | GATA binding protein 4 | 生化活动 | Biogrid | 11585926 |
GMFB | GMF | glia maturation factor, beta | - | HPRD | 8639570 |
HDAC4 | HA6116 | HD4 | HDAC-A | HDACA | KIAA0288 | histone deacetylase 4 | - | HPRD,BioGRID | 11114188 |
HMMR | CD168 |ihabp |MGC119494 |MGC119495 |Rhamm | 透明质酸介导的运动受体(RHAMM) | 亲和力捕获 - 韦斯特恩 | Biogrid | 11403955 |
HSP90AA1 | FLJ31884 | HSP86 | HSP89A | HSP90A | HSP90N | HSPC1 | HSPCA | HSPCAL1 | HSPCAL4 | HSPN | Hsp89 | Hsp90 | LAP2 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | - | HPRD | 11748628 |
IER3 | DIF-2 | DIF2 | GLY96 | IEX-1 | IEX-1L | IEX1 | PRG1 | immediate early response 3 | 生化活动 | Biogrid | 12356731 |
IFNAR1 | AVP | IFN-alpha-REC | IFNAR | IFNBR | IFRC | interferon (alpha, beta and omega) receptor 1 | - | HPRD | 9029147 |
INSR | CD220 | HHF5 | insulin receptor | 亲和力捕获 - 韦斯特恩 | Biogrid | 11409918 |
KLF11 | FKLF | FKLF1 | MODY7 | TIEG2 | Tieg3 | Kruppel-like factor 11 | - | HPRD | 12006497 |
KSR2 | FLJ25965 | kinase suppressor of ras 2 | - | HPRD | 12975377 |
MAP2K1 | MAPKK1 | MEK1 | MKK1 | PRKMK1 | mitogen-activated protein kinase kinase 1 | MEK1 interacts with and phosphorylates ERK2. This interaction is modeled on a demonstrated interaction between human MEK1 and rat ERK2. | BIND | 11134045 |
MAP2K1 | MAPKK1 | MEK1 | MKK1 | PRKMK1 | mitogen-activated protein kinase kinase 1 | 亲和力捕获 - 韦斯特恩 生化活动 重构的复合物 Two-hybrid |
Biogrid | 10757792|11266467 |11279118|11352917 |11823456|12697810 |
MAP2K2 | FLJ26075 | MAPKK2 | MEK2 | MKK2 | PRKMK2 | mitogen-activated protein kinase kinase 2 | MEK2 interacts with ERK2. This interaction is modeled on a demonstrated interaction between human MEK2 and rat ERK2. | BIND | 11134045 |
MAP2K2 | FLJ26075 | MAPKK2 | MEK2 | MKK2 | PRKMK2 | mitogen-activated protein kinase kinase 2 | - | HPRD,BioGRID | 11823456 |
MAP3K1 | MAPKKK1 | MEKK | MEKK1 | 有丝分裂原激活的蛋白激酶激酶激酶1 | 亲和力捕获 - 韦斯特恩 | Biogrid | 10969079 |
MAP3K1 | MAPKKK1 | MEKK | MEKK1 | 有丝分裂原激活的蛋白激酶激酶激酶1 | MEKK1 interacts with ERK2. | BIND | 10969079 |
MAPK14 | CSBP1 | CSBP2 | CSPB1 | EXIP | Mxi2 | PRKM14 | PRKM15 | RK | SAPK2A | p38 | p38ALPHA | 有丝分裂原激活的蛋白激酶14 | - | HPRD,BioGRID | 12697810 |
MAPKAPK2 | MK2 | 有丝分裂原激活的蛋白激酶激活的蛋白激酶2 | 亲和力捕获 - 韦斯特恩 | Biogrid | 15094067 |
MAPKAPK5 | prak | 有丝分裂原激活的蛋白激酶激活的蛋白激酶5 | - | HPRD | 9628874 |
MAPKSP1 | MAP2K1IP1 | MAPBP | MP1 | MAPK scaffold protein 1 | - | HPRD,BioGRID | 11266467 |
MBP | MGC99675 | myelin basic protein | MBPinteracts with MAPK1. This interaction was modeled on a demonstrated interaction between MBP from an unspecified species, and monkey and mouse MAPK1. | BIND | 9792705 |
MKNK1 | MNK1 | MAP kinase interacting serine/threonine kinase 1 | 重构的复合物 Two-hybrid |
Biogrid | 9155017 |
MKNK2 | GPRK7 | MNK2 | MAP kinase interacting serine/threonine kinase 2 | - | HPRD,BioGRID | 9155017 |
MYC | Bhlhe39 |c-myc | v-myc myelocytomatosis viral oncogene homolog (avian) | 生化活动 重构的复合物 |
Biogrid | 7957875|9207092 |15210690 |
NEK2 | HsPK21 | NEK2A | NLK1 | NIMA (never in mitosis gene a)-related kinase 2 | - | HPRD,BioGRID | 15358203 |
PEA15 | HMAT1 | HUMMAT1H | MAT1 | MAT1H | PEA-15 | PED | phosphoprotein enriched in astrocytes 15 | - | HPRD,BioGRID | 11702783 |
PEBP1 | HCNP | PBP | PEBP | RKIP | phosphatidylethanolamine binding protein 1 | - | HPRD,BioGRID | 10757792 |
PECAM1 | CD31 | PECAM-1 | platelet/endothelial cell adhesion molecule | 亲和力捕获 - 韦斯特恩 | Biogrid | 10801826 |
PLAT | DKFZp686I03148 | T-PA | TPA | plasminogen activator, tissue | - | HPRD | 15861134 |
PRKCE | MGC125656 |MGC125657 |PKCE |npkc-epsilon | protein kinase C, epsilon | 亲和力捕获 - 韦斯特恩 | Biogrid | 11350735 |
PTPN5 | FLJ14427 | PTPSTEP | STEP | protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) | 重构的复合物 | Biogrid | 9857190 |
PTPN7 | BPTP-4 | HEPTP | LC-PTP | LPTP | PTPNI | protein tyrosine phosphatase, non-receptor type 7 | - | HPRD,BioGRID | 10206983|10702794 |
PTPRH | FLJ39938 | MGC133058 | MGC133059 | SAP-1 | 蛋白酪氨酸磷酸酶,受体类型,H | - | HPRD | 11278335 |
PTPRR | DKFZp781C1038 | EC-PTP | FLJ34328 | MGC131968 | MGC148170 | PCPTP1 | PTP-SL | PTPBR7 | PTPRQ | 蛋白酪氨酸磷酸酶,受体类型,R | - | HPRD,BioGRID | 9857190 |
RAF1 | 克拉夫|NS5 |RAF-1 |C-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 | 亲和力捕获 - 韦斯特恩 | Biogrid | 11409918 |
RAF1 | 克拉夫|NS5 |RAF-1 |C-Raf | v-raf-1 murine leukemia viral oncogene homolog 1 | RAF-1与ERK2相互作用。这种相互作用是基于未指定物种的人RAF-1和ERK2之间的相互作用建模的。 | BIND | 15664191 |
RB1 | OSRC |RB |P105-RB |PRB |PP110 | retinoblastoma 1 | RB1被MAPK1磷酸化。这种相互作用是基于未指定物种的人类KIAA1536和MAPK1之间的相互作用进行建模的。 | BIND | 15489336 |
RPS6KA1 | HU-1 | MAPKAPK1A | RSK | RSK1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | - | HPRD,BioGRID | 9915826|12594221 |12832467 |
RPS6KA2 | HU-2 | MAPKAPK1C | RSK | RSK3 | S6K-alpha | S6K-alpha2 | p90-RSK3 | pp90RSK3 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | RSK3与ERK2相互作用。这种相互作用是建立在人RSK3和猴子ERK2之间的相互作用上的模型。 | BIND | 9915826 |
RPS6KA2 | HU-2 | MAPKAPK1C | RSK | RSK3 | S6K-alpha | S6K-alpha2 | p90-RSK3 | pp90RSK3 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | - | HPRD,BioGRID | 8939914 |
RPS6KA3 | CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | RSK | RSK2 | S6K-alpha3 | p90-RSK2 | pp90RSK2 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 亲和力捕获 - 韦斯特恩 | Biogrid | 8939914|9915826 |
RPS6KA3 | CLS | HU-3 | ISPK-1 | MAPKAPK1B | MRX19 | RSK | RSK2 | S6K-alpha3 | p90-RSK2 | pp90RSK2 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | - | HPRD | 12832467 |
RPS6KA4 | MSK2 | RSK-B | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | - | HPRD | 9687510 |
RPS6KA5 | MGC1911 | MSK1 | MSPK1 | RLPK | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | Phenotypic Enhancement | Biogrid | 9687510 |
SHC1 | 人体自燃现象FLJ26504 | | SHCA | SHC(SRC同源性2结构域)转化蛋白1 | - | HPRD,BioGRID | 10996427 |
SNCA | MGC110988 | NACP | PARK1 | PARK4 | PD1 | synuclein, alpha (non A4 component of amyloid precursor) | 亲和力捕获 - 韦斯特恩 | Biogrid | 12121974 |
SNCA | MGC110988 | NACP | PARK1 | PARK4 | PD1 | synuclein, alpha (non A4 component of amyloid precursor) | - | HPRD | 11279280 |
SNCG | BCSG1 |Sr | synuclein, gamma (breast cancer-specific protein 1) | 亲和力捕获 - 韦斯特恩 | Biogrid | 12121974 |
SORBS3 | 骗局1 |Scam1 |SH3D4 |葡萄蛋白 | sorbin and SH3 domain containing 3 | 亲和力捕获 - 韦斯特恩 生化活动 |
Biogrid | 15184391 |
SrEBF1 | SrEBP-1c | SREBP1 | bHLHd1 | sterol regulatory element binding transcription factor 1 | 生化活动 | Biogrid | 10627507 |
SrEBF2 | SrEBP2 | bHLHd2 | sterol regulatory element binding transcription factor 2 | - | HPRD,BioGRID | 10627507 |
Stat5A | MGF | STAT5 | signal transducer and activator of transcription 5A | - | HPRD,BioGRID | 10194762|10996427 |
Stat5B | Stat5 | signal transducer and activator of transcription 5B | - | HPRD | 10996427 |
TH | TYH | tyrosine hydroxylase | 生化活动 | Biogrid | 1347949 |
TNFSF11 | CD254 |ODF |OPGL |OPTB2 |rankl |tr |hrankl2 |SODF | tumor necrosis factor (ligand) superfamily, member 11 | - | HPRD | 10635328 |
TNIP1 | ABIN-1 | KIAA0113 | NAF1 | VAN | TNFAIP3相互作用蛋白1 | Naf1-alpha interacts with ERK2. | BIND | 12220502 |
TNIP1 | ABIN-1 | KIAA0113 | NAF1 | VAN | TNFAIP3相互作用蛋白1 | 亲和力捕获 - 韦斯特恩 重构的复合物 Two-hybrid |
Biogrid | 12220502 |
TNKS2 | PARP-5b | PARP-5c | PARP5B | PARP5C | TANK2 | TNKL | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | 生化活动 | Biogrid | 10988299 |
TOB1 | APRO6 | MGC104792 | MGC34446 | PIG49 | TOB | TROB | TROB1 | transducer of ERBB2, 1 | - | HPRD,BioGRID | 12151396 |
TP53 | FLJ92943 | LFS1 | TRP53 | p53 | tumor protein p53 | 亲和力捕获 - 韦斯特恩 | Biogrid | 10958792 |
TPR | - | translocated promoter region (to activated MET oncogene) | - | HPRD,BioGRID | 12594221 |
TSC2 | FLJ43106 | LAM | TSC4 | tuberous sclerosis 2 | 亲和力捕获 - 韦斯特恩 重构的复合物 |
Biogrid | 15851026 |
TSC2 | FLJ43106 | LAM | TSC4 | tuberous sclerosis 2 | Erk2 interacts with TSC2. This interaction was modelled on a demonstrated interaction between Erk2 from an unspecified species and human TSC2. | BIND | 15851026 |
UBR5 | DD5 |EDD |EDD1 |FLJ11310 |hyd |KIAA0896 |MGC57263 | ubiquitin protein ligase E3 component n-recognin 5 | - | HPRD,BioGRID | 12594221 |
VAV1 | VAV | VAV 1鸟嘌呤核苷酸交换因子 | - | HPRD,BioGRID | 8900182|9013873 |
VAV1 | VAV | VAV 1鸟嘌呤核苷酸交换因子 | Vav interacts with ERK2. | BIND | 9013873 |
Section V. Pathway annotation
Pathway name | 路径大小 | # SZGR 2.0 genes in pathway | 信息 |
---|---|---|---|
kegg mapk信号通路 | 267 | 205 | All SZGR 2.0 genes in this pathway |
KEGG ERBB SIGNALING PATHWAY | 87 | 71 | All SZGR 2.0 genes in this pathway |
KEGG趋化因子信号传导途径 | 190 | 128 | All SZGR 2.0 genes in this pathway |
Kegg卵母细胞减数分裂 | 114 | 79 | All SZGR 2.0 genes in this pathway |
kegg mtor信号通路 | 52 | 40 | All SZGR 2.0 genes in this pathway |
KEGG VASCULAR SMOOTH MUSCLE CONTRACTION | 115 | 81 | All SZGR 2.0 genes in this pathway |
KEGG DORSO VENTRAL AXIS FORMATION | 25 | 21 | All SZGR 2.0 genes in this pathway |
KEGG TGF BETA SIGNALING PATHWAY | 86 | 64 | All SZGR 2.0 genes in this pathway |
KEGG AXON GUIDANCE | 129 | 103 | All SZGR 2.0 genes in this pathway |
KEGG VEGF SIGNALING PATHWAY | 76 | 53 | All SZGR 2.0 genes in this pathway |
kegg焦点粘附 | 201 | 138 | All SZGR 2.0 genes in this pathway |
KEGG ADHERENS JUNCTION | 75 | 53 | All SZGR 2.0 genes in this pathway |
KEGG GAP JUNCTION | 90 | 68 | All SZGR 2.0 genes in this pathway |
KEGG TOLL LIKE RECEPTOR SIGNALING PATHWAY | 102 | 88 | All SZGR 2.0 genes in this pathway |
KEGG点头像受体信号通路 | 62 | 47 | All SZGR 2.0 genes in this pathway |
KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY | 137 | 92 | All SZGR 2.0 genes in this pathway |
KEGG T CELL RECEPTOR SIGNALING PATHWAY | 108 | 89 | All SZGR 2.0 genes in this pathway |
KEGG B CELL RECEPTOR SIGNALING PATHWAY | 75 | 56 | All SZGR 2.0 genes in this pathway |
kegg fc epsilon ri信号传导途径 | 79 | 58 | All SZGR 2.0 genes in this pathway |
KEGG FC GAMMA R MEDIATED PHAGOCYTOSIS | 97 | 71 | All SZGR 2.0 genes in this pathway |
KEGG LONG TERM POTENTIATION | 70 | 57 | All SZGR 2.0 genes in this pathway |
KEGG NEUROTROPHIN SIGNALING PATHWAY | 126 | 103 | All SZGR 2.0 genes in this pathway |
KEGG LONG TERM DEPRESSION | 70 | 53 | All SZGR 2.0 genes in this pathway |
KEGG REGULATION OF ACTIN CYTOSKELETON | 216 | 144 | All SZGR 2.0 genes in this pathway |
KEGG INSULIN SIGNALING PATHWAY | 137 | 103 | All SZGR 2.0 genes in this pathway |
KEGG GNRH SIGNALING PATHWAY | 101 | 77 | All SZGR 2.0 genes in this pathway |
KEGG孕酮介导的卵母细胞成熟 | 86 | 59 | All SZGR 2.0 genes in this pathway |
KEGG MELANOGENESIS | 102 | 80 | All SZGR 2.0 genes in this pathway |
KEGG TYPE II DIABETES MELLITUS | 47 | 41 | All SZGR 2.0 genes in this pathway |
KEGG ALDOSTERONE REGULATED SODIUM REABSORPTION | 42 | 29 | All SZGR 2.0 genes in this pathway |
KEGG ALZHEIMERS DISEASE | 169 | 110 | All SZGR 2.0 genes in this pathway |
KEGG PRION DISEASES | 35 | 28 | All SZGR 2.0 genes in this pathway |
KEGG LEISHMANIA INFECTION | 72 | 56 | All SZGR 2.0 genes in this pathway |
KEGG PATHWAYS IN CANCER | 328 | 259 | All SZGR 2.0 genes in this pathway |
KEGG COLORECTAL CANCER | 62 | 47 | All SZGR 2.0 genes in this pathway |
KEGG RENAL CELL CARCINOMA | 70 | 60 | All SZGR 2.0 genes in this pathway |
KEGG PANCREATIC CANCER | 70 | 56 | All SZGR 2.0 genes in this pathway |
KEGG ENDOMETRIAL CANCER | 52 | 45 | All SZGR 2.0 genes in this pathway |
Kegg神经胶质瘤 | 65 | 56 | All SZGR 2.0 genes in this pathway |
KEGG前列腺癌 | 89 | 75 | All SZGR 2.0 genes in this pathway |
KEGG甲状腺癌 | 29 | 26 | All SZGR 2.0 genes in this pathway |
KEGG MELANOMA | 71 | 57 | All SZGR 2.0 genes in this pathway |
Kegg膀胱癌 | 42 | 33 | All SZGR 2.0 genes in this pathway |
KEGG慢性髓细胞性白血病 | 73 | 59 | All SZGR 2.0 genes in this pathway |
Kegg急性髓样白血病 | 60 | 47 | All SZGR 2.0 genes in this pathway |
KEGG NON SMALL CELL LUNG CANCER | 54 | 47 | All SZGR 2.0 genes in this pathway |
BIOCARTA AGR PATHWAY | 36 | 31 | All SZGR 2.0 genes in this pathway |
BIOCARTA AT1R PATHWAY | 36 | 28 | All SZGR 2.0 genes in this pathway |
BIOCARTA SPPA PATHWAY | 22 | 18 | All SZGR 2.0 genes in this pathway |
生物卡丁生物肽途径 | 45 | 35 | All SZGR 2.0 genes in this pathway |
Biocarta CDMAC途径 | 16 | 15 | All SZGR 2.0 genes in this pathway |
Biocarta CCR3途径 | 23 | 21 | All SZGR 2.0 genes in this pathway |
BIOCARTA CERAMIDE PATHWAY | 22 | 16 | All SZGR 2.0 genes in this pathway |
Biocarta CXCR4途径 | 24 | 22 | All SZGR 2.0 genes in this pathway |
Biocarta ECM途径 | 24 | 17 | All SZGR 2.0 genes in this pathway |
BIOCARTA ERK PATHWAY | 28 | 22 | All SZGR 2.0 genes in this pathway |
BIOCARTA FCER1 PATHWAY | 41 | 30 | All SZGR 2.0 genes in this pathway |
BIOCARTA FMLP PATHWAY | 39 | 29 | All SZGR 2.0 genes in this pathway |
Biocarta GH途径 | 28 | 22 | All SZGR 2.0 genes in this pathway |
BIOCARTA MPR PATHWAY | 34 | 28 | All SZGR 2.0 genes in this pathway |
BIOCARTA HCMV PATHWAY | 17 | 16 | All SZGR 2.0 genes in this pathway |
BIOCARTA IL2RB PATHWAY | 38 | 26 | All SZGR 2.0 genes in this pathway |
BIOCARTA RACCYCD PATHWAY | 26 | 23 | All SZGR 2.0 genes in this pathway |
BIOCARTA INTEGRIN PATHWAY | 38 | 29 | All SZGR 2.0 genes in this pathway |
BIOCARTA KERATINOCYTE PATHWAY | 46 | 38 | All SZGR 2.0 genes in this pathway |
Biocarta Pyk2途径 | 31 | 24 | All SZGR 2.0 genes in this pathway |
BIOCARTA MAPK PATHWAY | 87 | 68 | All SZGR 2.0 genes in this pathway |
BIOCARTA MCALPAIN PATHWAY | 25 | 16 | All SZGR 2.0 genes in this pathway |
BIOCARTA PPARA PATHWAY | 58 | 43 | All SZGR 2.0 genes in this pathway |
BIOCARTA IGF1R PATHWAY | 23 | 20 | All SZGR 2.0 genes in this pathway |
BIOCARTA NFAT PATHWAY | 56 | 45 | All SZGR 2.0 genes in this pathway |
BIOCARTA ARENRF2 PATHWAY | 13 | 9 | All SZGR 2.0 genes in this pathway |
Biocarta EDG1途径 | 27 | 24 | All SZGR 2.0 genes in this pathway |
BIOCARTA CDK5 PATHWAY | 11 | 11 | All SZGR 2.0 genes in this pathway |
BIOCARTA PTEN PATHWAY | 18 | 14 | All SZGR 2.0 genes in this pathway |
BIOCARTA BAD PATHWAY | 26 | 23 | All SZGR 2.0 genes in this pathway |
BIOCARTA EIF4 PATHWAY | 24 | 19 | All SZGR 2.0 genes in this pathway |
BIOCARTA HER2 PATHWAY | 22 | 17 | All SZGR 2.0 genes in this pathway |
Biocarta ERK5途径 | 18 | 15 | All SZGR 2.0 genes in this pathway |
BIOCARTA MAL PATHWAY | 19 | 17 | All SZGR 2.0 genes in this pathway |
Biocarta Barr MAPK途径 | 12 | 11 | All SZGR 2.0 genes in this pathway |
BIOCARTA BARRESTIN SRC PATHWAY | 15 | 14 | All SZGR 2.0 genes in this pathway |
BIOCARTA MET PATHWAY | 37 | 30 | All SZGR 2.0 genes in this pathway |
Biocarta Spry途径 | 18 | 15 | All SZGR 2.0 genes in this pathway |
BIOCARTA CREB PATHWAY | 27 | 25 | All SZGR 2.0 genes in this pathway |
BIOCARTA TFF PATHWAY | 21 | 15 | All SZGR 2.0 genes in this pathway |
PC12细胞中的ST分化途径 | 45 | 35 | All SZGR 2.0 genes in this pathway |
SA B细胞受体复合物 | 24 | 20 | All SZGR 2.0 genes in this pathway |
ST ERK1 ERK2 MAPK PATHWAY | 32 | 25 | All SZGR 2.0 genes in this pathway |
SIG CD40PATHWAYMAP | 34 | 28 | All SZGR 2.0 genes in this pathway |
ST GA12 PATHWAY | 23 | 16 | All SZGR 2.0 genes in this pathway |
st g alpha的路径 | 16 | 11 | All SZGR 2.0 genes in this pathway |
ST G ALPHA I PATHWAY | 35 | 29 | All SZGR 2.0 genes in this pathway |
ST P38 MAPK PATHWAY | 37 | 28 | All SZGR 2.0 genes in this pathway |
SIG IL4RECEPTOR IN B LYPHOCYTES | 27 | 23 | All SZGR 2.0 genes in this pathway |
ST颗粒细胞存活途径 | 27 | 23 | All SZGR 2.0 genes in this pathway |
ST ADRENERGIC | 36 | 29 | All SZGR 2.0 genes in this pathway |
ST整合素信号通路 | 82 | 62 | All SZGR 2.0 genes in this pathway |
心肌细胞中的SIG胰岛素受体途径 | 51 | 41 | All SZGR 2.0 genes in this pathway |
ST T CELL SIGNAL TRANSDUCTION | 45 | 33 | All SZGR 2.0 genes in this pathway |
SIG BCR SIGNALING PATHWAY | 46 | 38 | All SZGR 2.0 genes in this pathway |
ST B CELL ANTIGEN RECEPTOR | 40 | 32 | All SZGR 2.0 genes in this pathway |
ST FAS SIGNALING PATHWAY | 65 | 54 | All SZGR 2.0 genes in this pathway |
ST MYOCYTE AD PATHWAY | 27 | 25 | All SZGR 2.0 genes in this pathway |
SA PTEN PATHWAY | 17 | 14 | All SZGR 2.0 genes in this pathway |
PID FCER1 PATHWAY | 62 | 43 | All SZGR 2.0 genes in this pathway |
PID内皮素路径 | 63 | 52 | All SZGR 2.0 genes in this pathway |
PID BCR 5PATHWAY | 65 | 50 | All SZGR 2.0 genes in this pathway |
PID PRL信号事件途径 | 23 | 17 | All SZGR 2.0 genes in this pathway |
PID ERBB4 PATHWAY | 38 | 32 | All SZGR 2.0 genes in this pathway |
PID GMCSF PATHWAY | 37 | 31 | All SZGR 2.0 genes in this pathway |
PID MET PATHWAY | 80 | 60 | All SZGR 2.0 genes in this pathway |
PID S1P S1P3 PATHWAY | 29 | 24 | All SZGR 2.0 genes in this pathway |
PID EPHB FWD途径 | 40 | 38 | All SZGR 2.0 genes in this pathway |
PID AVB3 OPN PATHWAY | 31 | 29 | All SZGR 2.0 genes in this pathway |
PID S1P S1P4 PATHWAY | 14 | 11 | All SZGR 2.0 genes in this pathway |
PID PS1途径 | 46 | 39 | All SZGR 2.0 genes in this pathway |
PID步道路径 | 28 | 20 | All SZGR 2.0 genes in this pathway |
PID CDC42途径 | 70 | 51 | All SZGR 2.0 genes in this pathway |
PID RET路径 | 39 | 29 | All SZGR 2.0 genes in this pathway |
PID血管生成素受体途径 | 50 | 41 | All SZGR 2.0 genes in this pathway |
PID S1P S1P1 PATHWAY | 21 | 18 | All SZGR 2.0 genes in this pathway |
PID TELOMERASE PATHWAY | 68 | 48 | All SZGR 2.0 genes in this pathway |
PID NETRIN PATHWAY | 32 | 27 | All SZGR 2.0 genes in this pathway |
PID REG GR PATHWAY | 82 | 60 | All SZGR 2.0 genes in this pathway |
PID ARF6 DOWNSTREAM PATHWAY | 15 | 14 | All SZGR 2.0 genes in this pathway |
PID MTOR 4PATHWAY | 69 | 55 | All SZGR 2.0 genes in this pathway |
PID IL2 1PATHWAY | 55 | 43 | All SZGR 2.0 genes in this pathway |
PID ERBB1 RECEPTOR PROXIMAL PATHWAY | 35 | 29 | All SZGR 2.0 genes in this pathway |
PID TCR RAS PATHWAY | 14 | 14 | All SZGR 2.0 genes in this pathway |
PID神经酰胺途径 | 48 | 37 | All SZGR 2.0 genes in this pathway |
PID AVB3 INTEGRIN PATHWAY | 75 | 53 | All SZGR 2.0 genes in this pathway |
PID IFNG PATHWAY | 40 | 34 | All SZGR 2.0 genes in this pathway |
PID ERBB1 DOWNSTREAM PATHWAY | 105 | 78 | All SZGR 2.0 genes in this pathway |
PID ATF2 PATHWAY | 59 | 43 | All SZGR 2.0 genes in this pathway |
PID ERBB2 ERBB3 PATHWAY | 44 | 35 | All SZGR 2.0 genes in this pathway |
PID BMP PATHWAY | 42 | 31 | All SZGR 2.0 genes in this pathway |
PID ALK1 PATHWAY | 26 | 21 | All SZGR 2.0 genes in this pathway |
PID PDGFRB PATHWAY | 129 | 103 | All SZGR 2.0 genes in this pathway |
PID TRKR PATHWAY | 62 | 48 | All SZGR 2.0 genes in this pathway |
PID SYNDECAN 1 PATHWAY | 46 | 29 | All SZGR 2.0 genes in this pathway |
PID RETINOIC ACID PATHWAY | 30 | 23 | All SZGR 2.0 genes in this pathway |
PID AR NONGENOMIC PATHWAY | 31 | 27 | All SZGR 2.0 genes in this pathway |
PID CXCR3 PATHWAY | 43 | 34 | All SZGR 2.0 genes in this pathway |
PID VEGFR1 PATHWAY | 26 | 23 | All SZGR 2.0 genes in this pathway |
PID SMAD2 3 Pathway | 17 | 13 | All SZGR 2.0 genes in this pathway |
PID VEGFR1 2 PATHWAY | 69 | 57 | All SZGR 2.0 genes in this pathway |
PID Syndecan 2途径 | 33 | 27 | All SZGR 2.0 genes in this pathway |
PID ANTHRAX PATHWAY | 17 | 15 | All SZGR 2.0 genes in this pathway |
PID S1P S1P2 PATHWAY | 24 | 19 | All SZGR 2.0 genes in this pathway |
PID MAPK TRK PATHWAY | 34 | 31 | All SZGR 2.0 genes in this pathway |
PID CD8 TCR DOWNSTREAM PATHWAY | 65 | 56 | All SZGR 2.0 genes in this pathway |
PID LYMPH ANGIOGENESIS PATHWAY | 25 | 16 | All SZGR 2.0 genes in this pathway |
PID ALPHA SYNUCLEIN PATHWAY | 33 | 25 | All SZGR 2.0 genes in this pathway |
PID FGF PATHWAY | 55 | 37 | All SZGR 2.0 genes in this pathway |
PID FAK PATHWAY | 59 | 45 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALLING BY NGF | 217 | 167 | All SZGR 2.0 genes in this pathway |
SCF套件的Reactome信号传导 | 78 | 59 | All SZGR 2.0 genes in this pathway |
REACTOME DEVELOPMENTAL BIOLOGY | 396 | 292 | All SZGR 2.0 genes in this pathway |
REACTOME SPRY REGULATION OF FGF SIGNALING | 14 | 9 | All SZGR 2.0 genes in this pathway |
REACTOME GROWTH HORMONE RECEPTOR SIGNALING | 24 | 19 | All SZGR 2.0 genes in this pathway |
REACTOME TRIF MEDIATED TLR3 SIGNALING | 74 | 54 | All SZGR 2.0 genes in this pathway |
REACTOME NEGATIVE REGULATION OF FGFR SIGNALING | 37 | 24 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY ERBB4 | 90 | 67 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY ERBB2 | 101 | 78 | All SZGR 2.0 genes in this pathway |
REACTOME GRB2 EVENTS IN ERBB2 SIGNALING | 22 | 20 | All SZGR 2.0 genes in this pathway |
EGFR在癌症中的反应组信号传导 | 109 | 80 | All SZGR 2.0 genes in this pathway |
ERBB4信号中的Reactome SHC1事件 | 20 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME INSULIN RECEPTOR SIGNALLING CASCADE | 87 | 64 | All SZGR 2.0 genes in this pathway |
REACTOME ARMS MEDIATED ACTIVATION | 17 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME PROLONGED ERK ACTIVATION EVENTS | 19 | 18 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALLING TO RAS | 27 | 23 | All SZGR 2.0 genes in this pathway |
REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE | 137 | 105 | All SZGR 2.0 genes in this pathway |
向ERK的Reactome信号传导 | 36 | 30 | All SZGR 2.0 genes in this pathway |
FGFR的Reactome信号传导IN DISEASE | 127 | 88 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALLING TO P38 VIA RIT AND RIN | 15 | 14 | All SZGR 2.0 genes in this pathway |
REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK | 205 | 136 | All SZGR 2.0 genes in this pathway |
REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | 24 | 20 | All SZGR 2.0 genes in this pathway |
REACTOME ERKS ARE INACTIVATED | 12 | 9 | All SZGR 2.0 genes in this pathway |
REACTOME SHC1 EVENTS IN EGFR SIGNALING | 15 | 13 | All SZGR 2.0 genes in this pathway |
REACTOME ERK MAPK TARGETS | 21 | 17 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | 186 | 155 | All SZGR 2.0 genes in this pathway |
REACTOME NEURONAL SYSTEM | 279 | 221 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY GPCR | 920 | 449 | All SZGR 2.0 genes in this pathway |
REACTOME OPIOID SIGNALLING | 78 | 56 | All SZGR 2.0 genes in this pathway |
REACTOME CA DEPENDENT EVENTS | 30 | 23 | All SZGR 2.0 genes in this pathway |
REACTOME NEUROTRANSMITTER RECEPTOR BINDING AND DOWNSTREAM TRANSMISSION IN THE POSTSYNAPTIC CELL | 137 | 110 | All SZGR 2.0 genes in this pathway |
REACTOME PLC BETA MEDIATED EVENTS | 43 | 32 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY PDGF | 122 | 93 | All SZGR 2.0 genes in this pathway |
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | 95 | 76 | All SZGR 2.0 genes in this pathway |
REACTOME AXON GUIDANCE | 251 | 188 | All SZGR 2.0 genes in this pathway |
REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH | 64 | 49 | All SZGR 2.0 genes in this pathway |
REACTOME ACTIVATION OF NMDA RECEPTOR UPON GLUTAMATE BINDING AND POSTSYNAPTIC EVENTS | 37 | 32 | All SZGR 2.0 genes in this pathway |
REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | 27 | 23 | All SZGR 2.0 genes in this pathway |
REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS | 33 | 28 | All SZGR 2.0 genes in this pathway |
REACTOME FRS2 MEDIATED CASCADE | 36 | 27 | All SZGR 2.0 genes in this pathway |
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR | 100 | 74 | All SZGR 2.0 genes in this pathway |
TLR级联反应组MAP激酶激活 | 50 | 37 | All SZGR 2.0 genes in this pathway |
REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | 10 | 8 | All SZGR 2.0 genes in this pathway |
REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | 30 | 24 | All SZGR 2.0 genes in this pathway |
REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS | 32 | 20 | All SZGR 2.0 genes in this pathway |
REACTOME L1CAM INTERACTIONS | 86 | 62 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY ILS | 107 | 86 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNAL TRANSDUCTION BY L1 | 34 | 25 | All SZGR 2.0 genes in this pathway |
REACTOME RECYCLING PATHWAY OF L1 | 27 | 15 | All SZGR 2.0 genes in this pathway |
REACTOME TRAF6 MEDIATED INDUCTION OF NFKB AND MAP KINASES UPON TLR7 8 OR 9 ACTIVATION | 77 | 57 | All SZGR 2.0 genes in this pathway |
REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | 13 | 11 | All SZGR 2.0 genes in this pathway |
REACTOME NFKB AND MAP KINASES ACTIVATION MEDIATED BY TLR4 SIGNALING REPERTOIRE | 72 | 53 | All SZGR 2.0 genes in this pathway |
Reactome IL 2信号传导 | 41 | 34 | All SZGR 2.0 genes in this pathway |
REACTOME SIGNALING BY INSULIN RECEPTOR | 108 | 72 | All SZGR 2.0 genes in this pathway |
REACTOME SOS MEDIATED SIGNALLING | 14 | 13 | All SZGR 2.0 genes in this pathway |
REACTOME HEMOSTASIS | 466 | 331 | All SZGR 2.0 genes in this pathway |
REACTOME RAF MAP KINASE CASCADE | 10 | 10 | All SZGR 2.0 genes in this pathway |
REACTOME SHC MEDIATED SIGNALLING | 15 | 12 | All SZGR 2.0 genes in this pathway |
REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE | 83 | 63 | All SZGR 2.0 genes in this pathway |
REACTOME INNATE IMMUNE SYSTEM | 279 | 178 | All SZGR 2.0 genes in this pathway |
REACTOME ACTIVATED TLR4 SIGNALLING | 93 | 69 | All SZGR 2.0 genes in this pathway |
REACTOME IMMUNE SYSTEM | 933 | 616 | All SZGR 2.0 genes in this pathway |
Reactome收费受体级联 | 118 | 84 | All SZGR 2.0 genes in this pathway |
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM | 270 | 204 | All SZGR 2.0 genes in this pathway |
REACTOME PLATELET ACTIVATION SIGNALING AND AGGREGATION | 208 | 138 | All SZGR 2.0 genes in this pathway |
FGFR的Reactome信号传导 | 112 | 80 | All SZGR 2.0 genes in this pathway |
REACTOME SHC RELATED EVENTS | 17 | 13 | All SZGR 2.0 genes in this pathway |
GAZDA钻石黑芬贫血髓样DN | 38 | 25 | All SZGR 2.0 genes in this pathway |
迪亚兹慢性巨态性白血病 | 1382 | 904 | All SZGR 2.0 genes in this pathway |
SENESE HDAC3 TARGETS DN | 536 | 332 | All SZGR 2.0 genes in this pathway |
Elvidge缺氧DN | 146 | 94 | All SZGR 2.0 genes in this pathway |
Bidus转移 | 214 | 134 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA POORLY DIFFERENTIATED UP | 633 | 376 | All SZGR 2.0 genes in this pathway |
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP | 722 | 443 | All SZGR 2.0 genes in this pathway |
MARTIN INTERACT WITH HDAC | 44 | 31 | All SZGR 2.0 genes in this pathway |
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY DN | 382 | 224 | All SZGR 2.0 genes in this pathway |
AMIT EGF RESPONSE 480 MCF10A | 43 | 26 | All SZGR 2.0 genes in this pathway |
唱歌转移基质 | 110 | 70 | All SZGR 2.0 genes in this pathway |
CHESLER BRAIN D6MIT150 QTL TRANS | 9 | 7 | All SZGR 2.0 genes in this pathway |
tarte浆细胞与Plasmablast DN | 309 | 206 | All SZGR 2.0 genes in this pathway |
MOREAUX MULTIPLE MYELOMA BY TACI UP | 412 | 249 | All SZGR 2.0 genes in this pathway |
TACI UP淋巴细胞的淋巴细胞成熟 | 92 | 58 | All SZGR 2.0 genes in this pathway |
NATSUME RESPONSE TO INTERFERON BETA UP | 71 | 49 | All SZGR 2.0 genes in this pathway |
伊万诺娃造血晚期祖先 | 544 | 307 | All SZGR 2.0 genes in this pathway |
LU AGING BRAIN DN | 153 | 120 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE DN | 1237 | 837 | All SZGR 2.0 genes in this pathway |
BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
HENDRICKS SMARCA4 TARGETS DN | 53 | 34 | All SZGR 2.0 genes in this pathway |
Hedenfalk乳腺癌BRCA1与BRCA2 | 163 | 113 | All SZGR 2.0 genes in this pathway |
Krige对Tosedostat 6小时的反应 | 953 | 554 | All SZGR 2.0 genes in this pathway |
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP | 783 | 442 | All SZGR 2.0 genes in this pathway |
克拉斯的加沙表观遗传沉默 | 26 | 16 | All SZGR 2.0 genes in this pathway |
STEARMAN LUNG CANCER EARLY VS LATE UP | 125 | 89 | All SZGR 2.0 genes in this pathway |
OUILLETTE CLL 13Q14删除 | 74 | 40 | All SZGR 2.0 genes in this pathway |
BHATI G2M ARREST BY 2METHOXYESTRADIOL UP | 125 | 68 | All SZGR 2.0 genes in this pathway |
HUNSBERGER EXERCISE REGULATED GENES | 31 | 26 | All SZGR 2.0 genes in this pathway |
SWEET LUNG CANCER KRAS UP | 491 | 316 | All SZGR 2.0 genes in this pathway |
甜Kras致癌签名 | 89 | 56 | All SZGR 2.0 genes in this pathway |
BOYAULT LIVER CANCER SUBCLASS G23 UP | 52 | 35 | All SZGR 2.0 genes in this pathway |
li诱导了自然杀手DN | 116 | 83 | All SZGR 2.0 genes in this pathway |
Kim所有疾病Calb1 Corr Up | 548 | 370 | All SZGR 2.0 genes in this pathway |
PILON KLF1 TARGETS DN | 1972 | 1213 | All SZGR 2.0 genes in this pathway |
棕熊UVC响应很晚 | 317 | 190 | All SZGR 2.0 genes in this pathway |
IVANOVSKA MIR106B TARGETS | 90 | 56 | All SZGR 2.0 genes in this pathway |
LINSLEY MIR16 TARGETS | 206 | 127 | All SZGR 2.0 genes in this pathway |
PURBEY TARGETS OF CTBP1 NOT SATB1 DN | 448 | 282 | All SZGR 2.0 genes in this pathway |
Krieg缺氧不是通过KDM3A | 770 | 480 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | mirna seq | ||
---|---|---|---|---|---|
UTR开始 | UTR结束 | 匹配方法 | |||
miR-129-5p | 3882 | 3888 | 1A | HSA-MIR-129brain | CUUUUUGCGGUCUGGGCUUGC |
HSA-MIR-129-5p | CUUUUUGCGGUCUGGGCUUGCU | ||||
mir-132/212 | 1379 | 1386 | 1A,m8 | hsa-miR-212SZ | UAACAGUCUCCAGUCACGGCC |
HSA-MIR-132brain | UAACAGUCUACAGCCAUGGUCG | ||||
miR-181 | 3842 | 3848 | m8 | HSA-MIR-181Abrain | AACAUUCAACGCUGUCGGUGAGU |
HSA-MIR-181BSZ | AACAUUCAUUGCUGUCGGUGGG | ||||
HSA-MIR-181Cbrain | AACAUUCAACCUGUCGGUGAGU | ||||
HSA-MIR-181Dbrain | AACAUUCAUUGUUGUCGGUGGGUU | ||||
miR-186 | 3798 | 3804 | m8 | HSA-MIR-186 | CAAAGAAUUCUCCUUUUGGGCUU |
mir-204/211 | 3259 | 3265 | 1A | hsa-miR-204brain | UUCCCUUUGUCAUCCUAUGCCU |
hsa-miR-211 | UUCCCUUUGUCAUCCUUCGCCU | ||||
miR-214 | 1168 | 1174 | 1A | hsa-miR-214brain | ACAGCAGGCACAGACAGGCAG |
miR-217 | 305 | 311 | m8 | hsa-miR-217 | UACUGCAUCAGGAACUGAUUGGAU |
mir-320 | 652 | 658 | m8 | hsa-miR-320 | aaaagcugggugagaggggcgaa |
mir-326 | 184 | 190 | 1A | hsa-miR-326 | CCUCUGGGCCCUUCCUCCAG |
mir-330 | 3194 | 3200 | m8 | hsa-miR-330brain | GCAAAGCACACGGCCUGCAGAGA |
miR-34b | 1594 | 1600 | m8 | hsa-miR-34b | UAGGCAGUGUCAUUAGCUGAUUG |
mir - 409 - 5p | 964 | 970 | 1A | HSA-MIR-409-5P | AGGUUACCCGAGCAACUUUGCA |
miR-493-5p | 1642 | 1648 | m8 | HSA-MIR-493-5p | UUGUACAUGGUAGGCUUUCAUU |
mir-539 | 1530 | 1537 | 1A,m8 | hsa-miR-539 | GGAGAAAUUAUCCUUGGUGUGU |
mir-543 | 3843 | 3849 | m8 | hsa-miR-543 | aaacauucgcggugcacuucu |