Gene Page:NSFL1C

Summary?
GeneID 55968
Symbol NSFL1C
Synonyms P47|UBX1|UBXD10|UBXN2C|dJ776F14.1
Description NSFL1 (p97) cofactor (p47)
Reference MIM:606610|HGNC: HGNC: 15912|Ensembl:ENSG00000088833|HPRD:09425|Vega:OTTHUMG00000031665
Gene type protein-coding
Map location 20p13
Pascal p-value 0.018
Sherlock p-value 0.99
eGene Myers' cis & trans
元
Support EXOCYTOSIS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
CompositeSet

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs6131468 chr20 1387686 NSFL1C 55968 0.15 cis
rs4814229 chr20 1388218 NSFL1C 55968 0.16 cis
rs5019244 chr20 1402160 NSFL1C 55968 0.18 cis
rs6042244 chr20 1413091 NSFL1C 55968 0.03 cis
rs6042292 chr20 1419198 NSFL1C 55968 0.03 cis
rs932524 chr20 1420335 NSFL1C 55968 0.01 cis
rs3171292 chr20 1423908 NSFL1C 55968 0.01 cis
rs1499662 chr1 56057848 NSFL1C 55968 0.16 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
RBM41 0.81 0.84
TTC37 0.81 0.83
TIAL1 0.81 0.85
PLEKHA5 0.81 0.83
ZNF655 0.80 0.83
RBL2 0.80 0.82
KIAA0528 0.80 0.82
USP48 0.80 0.82
SENP6 0.80 0.82
KIAA1704 0.79 0.84
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.31 -0.69 -0.71
MT-CO2 -0.67 -0.70
AF347015.21 -0.66 -0.70
HIGD1B -0.65 -0.70
IFI27 -0.65 -0.69
MT-CYB -0.65 -0.67
AF347015.27 -0.65 -0.68
AF347015.8 -0.64 -0.68
AF347015.2 -0.63 -0.67
AF347015.33 -0.61 -0.64

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0008289 lipid binding IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005794 Golgi apparatus IEA -
GO:0005634 nucleus IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
CHARAFE BREAST CANCER LUMINAL VS BASAL DN 455 304 All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418 263 All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278 748 All SZGR 2.0 genes in this pathway
CONCANNON APOPTOSIS BY EPOXOMICIN UP 239 157 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 1781 1082 All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN DN 770 415 All SZGR 2.0 genes in this pathway
OLSSON E2F3 TARGETS UP 28 14 All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584 395 All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP 424 268 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE INCIPIENT DN 165 106 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022 619 All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354 216 All SZGR 2.0 genes in this pathway
GRADE COLON CANCER UP 871 505 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504 321 All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824 528 All SZGR 2.0 genes in this pathway