Gene Page:PSKH1
Summary?
| GeneID | 5681 |
| Symbol | PSKH1 |
| Synonyms | - |
| Description | protein serine kinase H1 |
| Reference | MIM:177015|HGNC:HGNC:9529|运用:ENSG00000159792|HPRD:01511|Vega:OTTHUMG00000137548 |
| Gene type | protein-coding |
| Map location | 16q22.1 |
| Pascal p-value | 2.409E-4 |
| Sherlock p-value | 0.737 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs7396178 | 0 | PSKH1 | 5681 | 0.17 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| PPME1 | 0.91 | 0.88 |
| PSMD1 | 0.90 | 0.87 |
| GRPEL1 | 0.90 | 0.84 |
| GARS | 0.89 | 0.85 |
| SARS | 0.89 | 0.82 |
| PPP2CA | 0.89 | 0.86 |
| RRAGA | 0.88 | 0.83 |
| IMMT | 0.88 | 0.82 |
| RTCD1 | 0.88 | 0.83 |
| DDX1 | 0.88 | 0.83 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.8 | -0.78 | -0.64 |
| AF347015.2 | -0.78 | -0.63 |
| MT-CO2 | -0.77 | -0.62 |
| AF347015.26 | -0.77 | -0.64 |
| AF347015.33 | -0.76 | -0.63 |
| AF347015.21 | -0.76 | -0.60 |
| AF347015.15 | -0.76 | -0.63 |
| MT-CYB | -0.75 | -0.61 |
| AF347015.31 | -0.74 | -0.61 |
| AF347015.18 | -0.73 | -0.67 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| DODD NASOPHARYNGEAL CARCINOMA UP | 1821 | 933 | All SZGR 2.0 genes in this pathway |
| NUYTTEN EZH2 TARGETS UP | 1037 | 673 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| KAYO AGING MUSCLE DN | 123 | 76 | All SZGR 2.0 genes in this pathway |
| IVANOVA HEMATOPOIESIS STEM CELL AND PROGENITOR | 681 | 420 | All SZGR 2.0 genes in this pathway |
| ZHANG BREAST CANCER PROGENITORS DN | 145 | 93 | All SZGR 2.0 genes in this pathway |
| YAGI AML WITH 11Q23 REARRANGED | 351 | 238 | All SZGR 2.0 genes in this pathway |