Gene Page:RTN4

Summary?
GeneID 57142
Symbol RTN4
同义词 ASY|NI220/250|NOGO|NOGO-A|NOGOC|NSP|NSP-CL|Nbla00271|Nbla10545|Nogo-B|Nogo-C|RTN-X|RTN4-A|RTN4-B1|RTN4-B2|RTN4-C
描述 reticulon 4
参考 MIM:604475|HGNC：HGNC：14085|Ensembl:ENSG00000115310|HPRD：07259|Vega:OTTHUMG00000129337
Gene type protein-coding
Map location 2p16.3
Pascal P值 0.014
Sherlock p-value 0.606
Fetal beta -5.336
DMG 2 (# studies)
eGene Anterior cingulate cortex BA24
Caudate basal ganglia
Cerebellar Hemisphere
Cerebellum
Cortex
Frontal Cortex BA9
Hippocampus
Hypothalamus
Nucleus accumbens basal ganglia
梭子基底神经节
Myers' cis & trans
Meta
Support G2Cdb.humanPSD
G2Cdb.humanPSP
COMPOSITESET
Darnell FMRP targets

Gene in Data Sources
Gene set name 基因组方法 描述 Info
简历：PGCNP Genome-wide Association Study GWAS
DMG:Jaffe_2016 Genome-wide DNA methylation analysis This dataset includes 2,104 probes/CpGs associated with SZ patients (n=108) compared to 136 controls at Bonferroni-adjusted P < 0.05. 2
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 2
PMID:cooccur 高通量文献搜索 Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Association 组合的优势比方法（Sun et al. 2008），协会研究 2 Link to SZGene
文学 高通量文献搜索 Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenias Click to show details
GO_Annotation Mapping neuro-related keywords to Gene Ontology annotations Hits with neuro-related keywords: 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg26161045 2 55277080 RTN4 1.634E-4 -0.238 0.033 DMG:Wockner_2014
cg01555122 2 55276516 RTN4 3.67E-9 -0.026 2.35E-6 DMG:Jaffe_2016

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs10994209 chr10 61877705 RTN4 57142 0.17 trans
rs11125553 2 55186928 RTN4 ENSG00000115310.13 1.777E-6 0 152829 gtex_brain_ba24
rs2580764 2 55196956 RTN4 ENSG00000115310.13 1.235E-6 0 142801 gtex_brain_ba24
rs2588510 2 55199248 RTN4 ENSG00000115310.13 1.149E-8 0 140509 gtex_brain_ba24
rs5831331 2 55199557 RTN4 ENSG00000115310.13 1.077E-8 0 140200 gtex_brain_ba24
rs2255112 2 55200800 RTN4 ENSG00000115310.13 1.149E-8 0 138957 gtex_brain_ba24
rs2588521 2 55203931 RTN4 ENSG00000115310.13 1.149E-8 0 135826 gtex_brain_ba24
rs2580765 2 55204028 RTN4 ENSG00000115310.13 1.149E-8 0 135729 gtex_brain_ba24
rs2588514 2 55209177 RTN4 ENSG00000115310.13 8.756E-8 0 130580 gtex_brain_ba24
rs2919129 2 55216545 RTN4 ENSG00000115310.13 1.735E-7 0 123212 gtex_brain_ba24
rs2015919 2 55218026 RTN4 ENSG00000115310.13 4.898E-7 0 121731 gtex_brain_ba24
rs2580772 2 55218805 RTN4 ENSG00000115310.13 3.034E-8 0 120952 gtex_brain_ba24
rs2580773 2 55219989 RTN4 ENSG00000115310.13 1.012E-6 0 119768 gtex_brain_ba24
RS2580776 2 55222132 RTN4 ENSG00000115310.13 1.87E-7 0 117625 gtex_brain_ba24
rs10210840 2 55226009 RTN4 ENSG00000115310.13 1.018E-6 0 113748 gtex_brain_ba24
rs7340476 2 55227346 RTN4 ENSG00000115310.13 2.087E-7 0 112411 gtex_brain_ba24
rs13387751 2 55227375 RTN4 ENSG00000115310.13 2.092E-7 0 112382 gtex_brain_ba24
rs6545466 2 55228392 RTN4 ENSG00000115310.13 8.722E-7 0 111365 gtex_brain_ba24
rs6760429 2 55228499 RTN4 ENSG00000115310.13 2.227E-7 0 111258 gtex_brain_ba24
rs12713284 2 55228861 RTN4 ENSG00000115310.13 2.175E-7 0 110896 gtex_brain_ba24
rs7562292 2 55230219 RTN4 ENSG00000115310.13 1.603E-7 0 109538 gtex_brain_ba24
rs6726158 2 55239202 RTN4 ENSG00000115310.13 8.511E-7 0 100555 gtex_brain_ba24
rs6755468 2 55240026 RTN4 ENSG00000115310.13 1.862E-7 0 99731 gtex_brain_ba24
rs10174838 2 55241216 RTN4 ENSG00000115310.13 8.31E-8 0 98541 gtex_brain_ba24
rs7584430 2 55241686 RTN4 ENSG00000115310.13 1.692E-7 0 98071 gtex_brain_ba24
rs35631428 2 55244438 RTN4 ENSG00000115310.13 1.731E-6 0 95319 gtex_brain_ba24
RS12477711 2 55245177 RTN4 ENSG00000115310.13 2.045E-6 0 94580 gtex_brain_ba24
rs2044291 2 55247954 RTN4 ENSG00000115310.13 2.218E-7 0 91803 gtex_brain_ba24
RS11687609 2 55192280 RTN4 ENSG00000115310.13 3.626E-6 0 147477 gtex_brain_putamen_basal
rs2580764 2 55196956 RTN4 ENSG00000115310.13 5.459E-7 0 142801 gtex_brain_putamen_basal
rs2255393 2 55197882 RTN4 ENSG00000115310.13 6.598E-11 0 141875 gtex_brain_putamen_basal
rs2289747 2 55198385 RTN4 ENSG00000115310.13 4.372E-8 0 141372 gtex_brain_putamen_basal
rs2241959 2 55198399 RTN4 ENSG00000115310.13 4.227E-7 0 141358 gtex_brain_putamen_basal
rs887 2 55199068 RTN4 ENSG00000115310.13 1.656E-8 0 140689 gtex_brain_putamen_basal
rs2588510 2 55199248 RTN4 ENSG00000115310.13 2.626E-9 0 140509 gtex_brain_putamen_basal
rs5831331 2 55199557 RTN4 ENSG00000115310.13 9.963E-10 0 140200 gtex_brain_putamen_basal
rs2255112 2 55200800 RTN4 ENSG00000115310.13 2.626E-9 0 138957 gtex_brain_putamen_basal
rs2588521 2 55203931 RTN4 ENSG00000115310.13 2.626E-9 0 135826 gtex_brain_putamen_basal
rs2580765 2 55204028 RTN4 ENSG00000115310.13 2.626E-9 0 135729 gtex_brain_putamen_basal
rs2588514 2 55209177 RTN4 ENSG00000115310.13 2.502E-7 0 130580 gtex_brain_putamen_basal
rs17418675 2 55210605 RTN4 ENSG00000115310.13 1.874E-6 0 129152 gtex_brain_putamen_basal
RS12464447 2 55212495 RTN4 ENSG00000115310.13 2.489E-6 0 127262 gtex_brain_putamen_basal
rs2919129 2 55216545 RTN4 ENSG00000115310.13 7.281E-8 0 123212 gtex_brain_putamen_basal
rs2015919 2 55218026 RTN4 ENSG00000115310.13 1.153E-7 0 121731 gtex_brain_putamen_basal
rs10496036 2 55218791 RTN4 ENSG00000115310.13 3.343E-6 0 120966 gtex_brain_putamen_basal
rs2580772 2 55218805 RTN4 ENSG00000115310.13 7.281E-8 0 120952 gtex_brain_putamen_basal
rs2580773 2 55219989 RTN4 ENSG00000115310.13 1.721E-7 0 119768 gtex_brain_putamen_basal
rs17046570 2 55220584 RTN4 ENSG00000115310.13 3.343E-6 0 119173 gtex_brain_putamen_basal
RS2580776 2 55222132 RTN4 ENSG00000115310.13 8.517E-8 0 117625 gtex_brain_putamen_basal
rs55659423 2 55222630 RTN4 ENSG00000115310.13 3.55E-6 0 117127 gtex_brain_putamen_basal
rs55698303 2 55222680 RTN4 ENSG00000115310.13 3.337E-6 0 117077 gtex_brain_putamen_basal
rs2588518 2 55223282 RTN4 ENSG00000115310.13 5.4E-8 0 116475 gtex_brain_putamen_basal
rs72795431 2 55225303 RTN4 ENSG00000115310.13 2.648E-6 0 114454 gtex_brain_putamen_basal
rs10210840 2 55226009 RTN4 ENSG00000115310.13 8.612E-7 0 113748 gtex_brain_putamen_basal
rs7340476 2 55227346 RTN4 ENSG00000115310.13 7.466E-8 0 112411 gtex_brain_putamen_basal
rs13387751 2 55227375 RTN4 ENSG00000115310.13 7.469E-8 0 112382 gtex_brain_putamen_basal
rs6545466 2 55228392 RTN4 ENSG00000115310.13 1.058E-7 0 111365 gtex_brain_putamen_basal
rs6760429 2 55228499 RTN4 ENSG00000115310.13 7.515E-8 0 111258 gtex_brain_putamen_basal
rs12713284 2 55228861 RTN4 ENSG00000115310.13 7.677E-8 0 110896 gtex_brain_putamen_basal
rs35826668 2 55229508 RTN4 ENSG00000115310.13 5.384E-7 0 110249 gtex_brain_putamen_basal
rs7562292 2 55230219 RTN4 ENSG00000115310.13 7.354E-8 0 109538 gtex_brain_putamen_basal
rs6726158 2 55239202 RTN4 ENSG00000115310.13 7.889E-7 0 100555 gtex_brain_putamen_basal
rs3806570 2 55239410 RTN4 ENSG00000115310.13 1.015E-7 0 100347 gtex_brain_putamen_basal
rs6755468 2 55240026 RTN4 ENSG00000115310.13 1.045E-7 0 99731 gtex_brain_putamen_basal
rs10174838 2 55241216 RTN4 ENSG00000115310.13 9.382e-8 0 98541 gtex_brain_putamen_basal
rs7584430 2 55241686 RTN4 ENSG00000115310.13 1.139E-8 0 98071 gtex_brain_putamen_basal
rs35631428 2 55244438 RTN4 ENSG00000115310.13 9.794E-7 0 95319 gtex_brain_putamen_basal
rs17046594 2 55244538 RTN4 ENSG00000115310.13 2.188E-6 0 95219 gtex_brain_putamen_basal
RS12477711 2 55245177 RTN4 ENSG00000115310.13 3.339E-8 0 94580 gtex_brain_putamen_basal
rs4672005 2 55246551 RTN4 ENSG00000115310.13 2.484e-7 0 93206 gtex_brain_putamen_basal
rs12464070 2 55247477 RTN4 ENSG00000115310.13 1.33E-7 0 92280 gtex_brain_putamen_basal
rs2044291 2 55247954 RTN4 ENSG00000115310.13 1.258E-7 0 91803 gtex_brain_putamen_basal
rs2902649 2 55248357 RTN4 ENSG00000115310.13 1.342E-7 0 91400 gtex_brain_putamen_basal
rs7570629 2 55255935 RTN4 ENSG00000115310.13 1.04E-6 0 83822 gtex_brain_putamen_basal
rs2968786 2 55264859 RTN4 ENSG00000115310.13 2.075E-6 0 74898 gtex_brain_putamen_basal
rs141145795 2 55265634 RTN4 ENSG00000115310.13 2.152E-6 0 74123 gtex_brain_putamen_basal
rs2968787 2 55265785 RTN4 ENSG00000115310.13 1.757E-7 0 73972 gtex_brain_putamen_basal
RS2972097 2 55267545 RTN4 ENSG00000115310.13 2.143E-6 0 72212 gtex_brain_putamen_basal
rs2860453 2 55270485 RTN4 ENSG00000115310.13 2.113E-7 0 69272 gtex_brain_putamen_basal
RS2920893 2 55270629 RTN4 ENSG00000115310.13 1.678E-7 0 69128 gtex_brain_putamen_basal
rs2920900 2 55280083 RTN4 ENSG00000115310.13 1.184E-6 0 59674 gtex_brain_putamen_basal
rs2968790 2 55280594 RTN4 ENSG00000115310.13 6.018E-8 0 59163 gtex_brain_putamen_basal
rs1822616 2 55283878 RTN4 ENSG00000115310.13 6.838e-8 0 55879 gtex_brain_putamen_basal
rs2968793 2 55285024 RTN4 ENSG00000115310.13 4.883E-8 0 54733 gtex_brain_putamen_basal
rs13011689 2 55287079 RTN4 ENSG00000115310.13 1.085E-7 0 52678 gtex_brain_putamen_basal
rs2968796 2 55287835 RTN4 ENSG00000115310.13 5.102E-8 0 51922 gtex_brain_putamen_basal
rs2968795 2 55287989 RTN4 ENSG00000115310.13 1.083E-7 0 51768 gtex_brain_putamen_basal
rs565402040 2 55289148 RTN4 ENSG00000115310.13 8.566E-7 0 50609 gtex_brain_putamen_basal
rs2968794 2 55290651 RTN4 ENSG00000115310.13 3.313E-7 0 49106 gtex_brain_putamen_basal
rs11674808 2 55291671 RTN4 ENSG00000115310.13 1.418E-7 0 48086 gtex_brain_putamen_basal
RS2972075 2 55292322 RTN4 ENSG00000115310.13 1.328E-7 0 47435 gtex_brain_putamen_basal
RS34557804 2 55294571 RTN4 ENSG00000115310.13 1.313E-7 0 45186 gtex_brain_putamen_basal
RS2972072 2 55295370 RTN4 ENSG00000115310.13 5.686 e-8 0 44387 gtex_brain_putamen_basal
RS2920878 2 55296415 RTN4 ENSG00000115310.13 1.338E-7 0 43342 gtex_brain_putamen_basal
RS2968827 2 55297629 RTN4 ENSG00000115310.13 1.797E-7 0 42128 gtex_brain_putamen_basal
RS2972071 2 55300749 RTN4 ENSG00000115310.13 6.272E-8 0 39008 gtex_brain_putamen_basal
RS2972070 2 55301691 RTN4 ENSG00000115310.13 1.697E-7 0 38066 gtex_brain_putamen_basal
RS2968825 2 55303042 RTN4 ENSG00000115310.13 3.822e-7 0 36715 gtex_brain_putamen_basal
RS2968822 2 55307811 RTN4 ENSG00000115310.13 2.619E-7 0 31946 gtex_brain_putamen_basal
RS2968821 2 55307865 RTN4 ENSG00000115310.13 9.645E-9 0 31892 gtex_brain_putamen_basal
RS2920891 2 55308037 RTN4 ENSG00000115310.13 1.035E-8 0 31720 gtex_brain_putamen_basal
RS2920882 2 55312270 RTN4 ENSG00000115310.13 3.034E-6 0 27487 gtex_brain_putamen_basal
rs2968798 2 55314611 RTN4 ENSG00000115310.13 2.905E-6 0 25146 gtex_brain_putamen_basal
RS2920862 2 55316938 RTN4 ENSG00000115310.13 1.943E-6 0 22819 gtex_brain_putamen_basal
RS2968805 2 55319460 RTN4 ENSG00000115310.13 3.187E-6 0 20297 gtex_brain_putamen_basal
RS2968809 2 55323803 RTN4 ENSG00000115310.13 1.865E-6 0 15954 gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去后m Evidence Neuro keywords PubMed ID
GO:0005515 protein binding IPI 11126360
Biological process 去后m Evidence Neuro keywords PubMed ID
GO:0030517 negative regulation of axon extension IDA Axon（GO术语级别：15） 10667797
GO:0019987 negative regulation of anti-apoptosis IMP 11126360
GO:0042981 regulation of apoptosis NAS 11126360
GO:0030334 regulation of cell migration IDA 15034570
细胞分量 去后m Evidence Neuro keywords PubMed ID
GO:0005789 endoplasmic reticulum membrane IEA -
GO:0005635 nuclear envelope IDA 11126360
GO:0005783 endoplasmic reticulum IEA -
GO:0005783 endoplasmic reticulum NAS 11126360
GO:0016020 membrane IEA -
GO:0016021 integral to membrane IEA -
去：0030176 内质网膜的整体 IDA 10667797

Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B Experimental 资源 PubMed ID
BCL2 Bcl-2 B-cell CLL/lymphoma 2 RTN-XS interacts with Bcl-2. BIND 11126360
BCL2 Bcl-2 B-cell CLL/lymphoma 2 - HPRD,BioGRID 11126360
BCL2L1 BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xS BCL2-like 1 - HPRD,BioGRID 11126360
BCL2L1 BCL-XL/S | BCL2L | BCLX | Bcl-X | DKFZp781P2092 | bcl-xL | bcl-xS BCL2-like 1 RTN-XS与BCl-XL相互作用。 BIND 11126360
CNTNAP1 Caspr |cntnap |nrxn4 |P190 contactin associated protein 1 - HPRD,BioGRID 14592966
Col4a3bp CERT | CERTL | FLJ20597 | GPBP | STARD11 IV型胶原蛋白,α3 (Goodpasture抗原)binding protein Two-hybrid BioGRID 16189514
CRMP1 DPYSL1 | DRP-1 | DRP1 collapsin response mediator protein 1 Two-hybrid BioGRID 16169070
FXR2 FMR1L2 fragile X mental retardation, autosomal homolog 2 Two-hybrid BioGRID 16189514
KCNA1 AEMK | EA1 | HBK1 | HUK1 | KV1.1 | MBK1 | MGC126782 | MGC138385 | MK1 | RBK1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) Affinity Capture-Western BioGRID 14592966
KCNA2 HBK5 | HK4 | HUKIV | KV1.2 | MGC50217 | MK2 | NGK1 | RBK2 potassium voltage-gated channel, shaker-related subfamily, member 2 Affinity Capture-Western BioGRID 14592966
LRCH4 FLJ40101 | FLJ46315 | LRN | LRRN1 | LRRN4 | PP14183 | SAP25 leucine-rich repeats and calponin homology (CH) domain containing 4 Two-hybrid BioGRID 16189514
LRPAP1 A2MRAP | A2RAP | HBP44 | MGC138272 | MRAP | RAP low density lipoprotein receptor-related protein associated protein 1 Two-hybrid BioGRID 16169070
NAPA SNAPA N-乙基马来酰亚胺敏感因子附着蛋白，α Two-hybrid BioGRID 16189514
PLEKHF2 FLJ13187 | PHAFIN2 | ZFYVE18 pleckstrin homology domain containing, family F (with FYVE domain) member 2 Two-hybrid BioGRID 16189514
PRR13 DKFZp564J157 | FLJ23818 | TXR1 proline rich 13 Two-hybrid BioGRID 16169070
rab33a MGC1488 | RabS10 rab33a, member RAS oncogene family Two-hybrid BioGRID 16189514
RTN3 ASYIP | HAP | NSPL2 | NSPLII | RTN3-A1 reticulon 3 Two-hybrid BioGRID 16189514
RTN4IP1 MGC12934 | NIMP reticulon 4 interacting protein 1 - HPRD,BioGRID 12067236
RTN4IP1 MGC12934 | NIMP reticulon 4 interacting protein 1 Nogo-A interacts with NIMP. BIND 12067236
RTN4R NGR | NOGOR reticulon 4 receptor - HPRD 11201742
RTN4R NGR | NOGOR reticulon 4 receptor Nogo-66 interacts with NgR. BIND 15694321
SIRT2 SIR2 | SIR2L | SIR2L2 Sirtuin（无声交配类型信息法规2同源物）2（S。cerevisiae） Affinity Capture-MS BioGRID 17353931
SPG21 ACP33 | BM-019 | GL010 | MASPARDIN | MAST spastic paraplegia 21 (autosomal recessive, Mast syndrome) Two-hybrid BioGRID 16189514
UQCRC1 D3S3191 | QCR1 | UQCR1 ubiquinol-cytochrome c reductase core protein I Nogo-A interacts with UQCRC1. BIND 12067236
UQCRC1 D3S3191 | QCR1 | UQCR1 ubiquinol-cytochrome c reductase core protein I - HPRD,BioGRID 12067236
UQCRC2 QCR2 | UQCR2 ubiquinol-cytochrome c reductase core protein II Nogo-A interacts with UQCRC2. BIND 12067236
UQCRC2 QCR2 | UQCR2 ubiquinol-cytochrome c reductase core protein II - HPRD,BioGRID 12067236


Section V. Pathway annotation

Pathway name Pathway size ＃szgr 2.0基因 Info
PID P75 NTR PATHWAY 69 51 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING BY NGF 217 167 All SZGR 2.0 genes in this pathway
REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING 81 61 All SZGR 2.0 genes in this pathway
WATANABE RECTAL CANCER RADIOTHERAPY RESPONSIVE DN 92 51 All SZGR 2.0 genes in this pathway
BERTUCCI MEDULLARY VS DUCTAL BREAST CANCER DN 169 118 All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 All SZGR 2.0 genes in this pathway
DEURIG T CELL PROLYMPHOCYTIC LEUKEMIA DN 320 184 All SZGR 2.0 genes in this pathway
CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL DN 460 312 All SZGR 2.0 genes in this pathway
LUI THYROID CANCER PAX8 PPARG DN 45 29 All SZGR 2.0 genes in this pathway
LUI THYROID CANCER CLUSTER 3 28 16 All SZGR 2.0 genes in this pathway
LUI TARGETS OF PAX8 PPARG FUSION 34 23 All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE DN 712 443 All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN UP 479 299 All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS DN 848 527 All SZGR 2.0 genes in this pathway
FUJIWARA PARK2 HEPATOCYTE PROLIFERATION DN 8 7 All SZGR 2.0 genes in this pathway
PETRETTO CARDIAC HYPERTROPHY 34 26 All SZGR 2.0 genes in this pathway
SANA RESPONSE TO IFNG DN 85 56 All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546 351 All SZGR 2.0 genes in this pathway
PENG RAPAMYCIN RESPONSE DN 245 154 All SZGR 2.0 genes in this pathway
hemin的addya红斑分化 73 47 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237 837 All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY NO BLOOD DN 150 93 All SZGR 2.0 genes in this pathway
KAAB HEART ATRIUM VS VENTRICLE UP 249 170 All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY DN 145 88 All SZGR 2.0 genes in this pathway
dazard对UV SCC的反应 123 75 All SZGR 2.0 genes in this pathway
LEE METASTASIS AND ALTERNATIVE SPLICING UP 74 51 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS UP 673 430 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS UP 602 364 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS UP 601 369 All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR UP 294 199 All SZGR 2.0 genes in this pathway
MOOTHA PGC 420 269 All SZGR 2.0 genes in this pathway
MILI PSEUDOPODIA CHEMOTAXIS DN 457 302 All SZGR 2.0 genes in this pathway
米利假足型haptotaxis dn 668 419 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS CALB1 CORR UP 548 370 All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824 528 All SZGR 2.0 genes in this pathway
TERAO AOX4 TARGETS SKIN UP 38 27 All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION DN 1080 713 All SZGR 2.0 genes in this pathway
GUILLAUMOND KLF10 TARGETS DN 30 15 All SZGR 2.0 genes in this pathway
rao由SALL4同工型B绑定 517 302 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family 目标位置 mirna id miRNA seq
UTR start UTR end Match method
miR-132/212 509 515 1A hsa-miR-212SZ UAACAGUCUCCAGUCACGGCC
hsa-miR-132脑 UAACAGUCUACAGCCAUGGUCG
miR-153 840 846 1A hsa-miR-153 Uugcauagucacaaaaguga
miR-182 522 528 m8 hsa-miR-182 UUUGGCAAUGGUAGAACUCACA
miR-218 649 655 m8 hsa-miR-218脑 UUGUGCUUGAUCUAACCAUGU
miR-448 840 846 1A hsa-miR-448 uugcauauguaggauguccccau
miR-455 651 657 1A hsa-miR-455 UAUGUGCCUUUGGACUACAUCG
mir-491 594 600 1A hsa-miR-491脑 AGUGGGGAACCCUUCCAUGAGGA