Gene Page:USP31

Summary?
GeneID 57478
Symbol USP31
Synonyms -
Description ubiquitin specific peptidase 31
Reference HGNC:HGNC:20060|Ensembl:ENSG00000103404|HPRD:15634|Vega:OTTHUMG00000094793
Gene type protein-coding
Map location 16p12.2
Pascal p-value 0.011
Fetal beta 0.628
eGene 元

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:GWASdb Genome-wide Association Studies GWASdb records for schizophrenia
CV:PGCnp Genome-wide Association Study GWAS
GSMA_IIE Genome scan meta-analysis (European-ancestry samples) Psr: 0.01775

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function GO term Evidence Neuro keywords PubMed ID
GO:0004221 泛素thiolesterase activity IEA -
GO:0008234 cysteine-type peptidase activity IEA -
GO:0008233 peptidase activity IEA -
Biological process GO term Evidence Neuro keywords PubMed ID
GO:0006511 ubiquitin-dependent protein catabolic process IEA -
Cellular component GO term Evidence Neuro keywords PubMed ID
GO:0005737 cytoplasm IDA 18029348

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
LIU SOX4 TARGETS UP 137 94 All SZGR 2.0 genes in this pathway
TURASHVILI BREAST DUCTAL CARCINOMA VS DUCTAL NORMAL DN 198 110 All SZGR 2.0 genes in this pathway
LIU TARGETS OF VMYB VS CMYB DN 43 30 All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278 748 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA DN 1375 806 All SZGR 2.0 genes in this pathway
RODRIGUES THYROID CARCINOMA ANAPLASTIC UP 722 443 All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY NO BLOOD UP 222 139 All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP 487 303 All SZGR 2.0 genes in this pathway
CHANG IMMORTALIZED BY HPV31 UP 84 55 All SZGR 2.0 genes in this pathway
DOUGLAS BMI1 TARGETS UP 566 371 All SZGR 2.0 genes in this pathway
DUTERTRE ESTRADIOL RESPONSE 6HR UP 229 149 All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882 538 All SZGR 2.0 genes in this pathway
KRIEG HYPOXIA NOT VIA KDM3A 770 480 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-101 4515 4521 1A hsa-miR-101 UACAGUACUGUGAUAACUGAAG
miR-134 796 802 m8 hsa-miR-134brain UGUGACUGGUUGACCAGAGGG
miR-135 210 216 1A hsa-miR-135a UAUGGCUUUUUAUUCCUAUGUGA
hsa-miR-135b UAUGGCUUUUCAUUCCUAUGUG
miR-144 4514 4521 1A,m8 hsa-miR-144 UACAGUAUAGAUGAUGUACUAG
miR-145 239 246 1A,m8 hsa-miR-145 GUCCAGUUUUCCCAGGAAUCCCUU
miR-15/16/195/424/497 1689 1696 1A,m8 hsa-miR-15abrain UAGCAGCACAUAAUGGUUUGUG
hsa-miR-16brain UAGCAGCACGUAAAUAUUGGCG
hsa-miR-15bbrain UAGCAGCACAUCAUGGUUUACA
hsa-miR-195SZ UAGCAGCACAGAAAUAUUGGC
hsa-miR-424 CAGCAGCAAUUCAUGUUUUGAA
hsa-miR-497 CAGCAGCACACUGUGGUUUGU
miR-17-5p/20/93.mr/106/519.d 510 516 m8 hsa-miR-17-5p CAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ CAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519d CAAAGUGCCUCCCUUUAGAGUGU
hsa-miR-17-5p CAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ CAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519d CAAAGUGCCUCCCUUUAGAGUGU
miR-218 3898 3904 m8 hsa-miR-218brain UUGUGCUUGAUCUAACCAUGU
miR-23 5632 5639 1A,m8 hsa-miR-23abrain AUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrain AUCACAUUGCCAGGGAUUACC
miR-24* 215 221 1A hsa-miR-189 GUGCCUACUGAGCUGAUAUCAGU
miR-29 6026 6032 1A hsa-miR-29aSZ UAGCACCAUCUGAAAUCGGUU
hsa-miR-29bSZ UAGCACCAUUUGAAAUCAGUGUU
hsa-miR-29cSZ UAGCACCAUUUGAAAUCGGU
miR-323 5632 5638 1A hsa-miR-323brain GCACAUUACACGGUCGACCUCU
miR-34/449 5128 5135 1A,m8 hsa-miR-34abrain UGGCAGUGUCUUAGCUGGUUGUU
hsa-miR-34c AGGCAGUGUAGUUAGCUGAUUGC
hsa-miR-449 UGGCAGUGUAUUGUUAGCUGGU
hsa-miR-449b AGGCAGUGUAUUGUUAGCUGGC
miR-378 2462 2468 1A hsa-miR-378 CUCCUGACUCCAGGUCCUGUGU
miR-494 561 567 m8 hsa-miR-494brain UGAAACAUACACGGGAAACCUCUU
miR-503 1690 1696 1A hsa-miR-503 UAGCAGCGGGAACAGUUCUGCAG
miR-505 4489 4495 1A hsa-miR-505 GUCAACACUUGCUGGUUUCCUC
miR-539 564 570 1A hsa-miR-539 GGAGAAAUUAUCCUUGGUGUGU
miR-9 65 71 m8 hsa-miR-9SZ UCUUUGGUUAUCUAGCUGUAUGA