基因页：PEX5
概括?
| 基因ID | 5830 |
| Symbol | PEX5 |
| 同义词 | pbd2a | pbd2b | pts1-bp | pts1r | pxr1 | rcdp5 |
| 描述 | peroxisomal biogenesis factor 5 |
| 参考 | MIM:600414|HGNC：HGNC：9719|Ensembl:ENSG00000139197|HPRD:02684|Vega:OTTHUMG00000168175 |
| 基因type | protein-coding |
| 地图位置 | 12p13.31 |
| Pascal P值 | 0.05 |
| Sherlock P值 | 0.112 |
| Fetal beta | -0.319 |
| DMG | 3 (# studies) |
| eGene | 前扣带回皮层BA24 尾状基底神经节 Cortex 额叶皮质BA9 Hippocampus 下丘脑 Nucleus accumbens basal ganglia 梭子基底神经节 迈尔斯的顺式和跨性别 Meta |
| 支持 | Ascano FMRP目标 |
数据源中的基因
| 基因set name | 基因组方法 | 描述 | Info |
|---|---|---|---|
| 简历：PGCNP | 全基因组协会研究 | GWAS | |
| DMG:Jaffe_2016 | 通用电气nome-wide DNA methylation analysis | 该数据集包括与SZ患者相关的2,104个探针/CPG（n = 108），而在Bonferroni调整后的P <0.05时，其中136个对照。 | 3 |
| DMG:Nishioka_2013 | 通用电气nome-wide DNA methylation analysis | The authors investigated the methylation profiles of DNA in peripheral blood cells from 18 patients with first-episode schizophrenia (FESZ) and from 15 normal controls. | 3 |
| DMG:Wockner_2014 | 通用电气nome-wide DNA methylation analysis | This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). | 3 |
| go_annotation | Mapping neuro-related keywords to Gene Ontology annotations | Hits with neuro-related keywords: 2 |
第一节遗传学和表观遗传学注释
差异甲基化基因
差异甲基化基因| 探测 | Chromosome | Position | 最近的基因 | P (dis) | beta（dis） | FDR (dis) | Study |
|---|---|---|---|---|---|---|---|
| CG05236530 | 12 | 7362357 | PEX5 | 5.888E-4 | 0.364 | 0.05 | DMG:Wockner_2014 |
| CG15754084 | 12 | 7343020 | PEX5 | -0.038 | 0.87 | DMG:Nishioka_2013 | |
| cg07748017 | 12 | 7342621 | PEX5 | 5.83E-8 | -0.012 | 1.49E-5 | DMG:Jaffe_2016 |
EQTL注释
| SNP ID | Chromosome | Position | eGene | 基因Entrez ID | PVALUE | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2456470 | CHR15 | 62777955 | PEX5 | 5830 | 0.19 | trans | ||
| RS2053887 | 12 | 7346530 | PEX5 | ENSG00000139197.6 | 1.478E-6 | 0.01 | 5249 | gtex_brain_ba24 |
| RS12830671 | 12 | 7347278 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 5997 | gtex_brain_ba24 |
| rs12820829 | 12 | 7347534 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 6253 | gtex_brain_ba24 |
| RS61917956 | 12 | 7348659 | PEX5 | ENSG00000139197.6 | 4.544e-7 | 0.01 | 7378 | gtex_brain_ba24 |
| rs78613188 | 12 | 7348728 | PEX5 | ENSG00000139197.6 | 9.674E-8 | 0.01 | 7447 | gtex_brain_ba24 |
| RS200498082 | 12 | 7348907 | PEX5 | ENSG00000139197.6 | 1.518E-7 | 0.01 | 7626 | gtex_brain_ba24 |
| RS61917957 | 12 | 7349987 | PEX5 | ENSG00000139197.6 | 7.538e-7 | 0.01 | 8706 | gtex_brain_ba24 |
| rs200609395 | 12 | 7350135 | PEX5 | ENSG00000139197.6 | 7.415e-8 | 0.01 | 8854 | gtex_brain_ba24 |
| RS185073397 | 12 | 7350136 | PEX5 | ENSG00000139197.6 | 5.77E-7 | 0.01 | 8855 | gtex_brain_ba24 |
| RS7139158 | 12 | 7350155 | PEX5 | ENSG00000139197.6 | 1.011E-7 | 0.01 | 8874 | gtex_brain_ba24 |
| rs7962563 | 12 | 7353514 | PEX5 | ENSG00000139197.6 | 8.647E-7 | 0.01 | 12233 | gtex_brain_ba24 |
| rs10743271 | 12 | 7353790 | PEX5 | ENSG00000139197.6 | 1.326E-7 | 0.01 | 12509 | gtex_brain_ba24 |
| rs7315553 | 12 | 7353838 | PEX5 | ENSG00000139197.6 | 8.667E-7 | 0.01 | 12557 | gtex_brain_ba24 |
| rs12825629 | 12 | 7355583 | PEX5 | ENSG00000139197.6 | 8.702E-7 | 0.01 | 14302 | gtex_brain_ba24 |
| RS6486910 | 12 | 7356479 | PEX5 | ENSG00000139197.6 | 3.866e-7 | 0.01 | 15198 | gtex_brain_ba24 |
| RS6486911 | 12 | 7356494 | PEX5 | ENSG00000139197.6 | 3.874E-7 | 0.01 | 15213 | gtex_brain_ba24 |
| rs7970916 | 12 | 7357746 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 16465 | gtex_brain_ba24 |
| rs75912799 | 12 | 7357897 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 16616 | gtex_brain_ba24 |
| rs10161405 | 12 | 7358646 | PEX5 | ENSG00000139197.6 | 3.071E-7 | 0.01 | 17365 | gtex_brain_ba24 |
| rs10161542 | 12 | 7358684 | PEX5 | ENSG00000139197.6 | 3.071E-7 | 0.01 | 17403 | gtex_brain_ba24 |
| RS11044332 | 12 | 7358768 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 17487 | gtex_brain_ba24 |
| RS111408486 | 12 | 7359175 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 17894 | gtex_brain_ba24 |
| rs397737333 | 12 | 7359309 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 18028 | gtex_brain_ba24 |
| RS3825405 | 12 | 7360143 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 18862 | gtex_brain_ba24 |
| rs3816424 | 12 | 7360229 | PEX5 | ENSG00000139197.6 | 1.42E-7 | 0.01 | 18948 | gtex_brain_ba24 |
| RS1057225 | 12 | 7363574 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 22293 | gtex_brain_ba24 |
| rs11448434 | 12 | 7363943 | PEX5 | ENSG00000139197.6 | 1.015E-8 | 0.01 | 22662 | gtex_brain_ba24 |
| rs4329748 | 12 | 7364442 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 23161 | gtex_brain_ba24 |
| rs4492891 | 12 | 7364789 | PEX5 | ENSG00000139197.6 | 1.497E-6 | 0.01 | 23508 | gtex_brain_ba24 |
| RS200081407 | 12 | 7366581 | PEX5 | ENSG00000139197.6 | 8.857E-7 | 0.01 | 25300 | gtex_brain_ba24 |
| RS12228393 | 12 | 7368182 | PEX5 | ENSG00000139197.6 | 8.763E-7 | 0.01 | 26901 | gtex_brain_ba24 |
| RS10161170 | 12 | 7368629 | PEX5 | ENSG00000139197.6 | 1.422E-7 | 0.01 | 27348 | gtex_brain_ba24 |
| rs11044901 | 12 | 7368691 | PEX5 | ENSG00000139197.6 | 1.413E-7 | 0.01 | 27410 | gtex_brain_ba24 |
| rs10161103 | 12 | 7369087 | PEX5 | ENSG00000139197.6 | 1.42E-7 | 0.01 | 27806 | gtex_brain_ba24 |
| RS7969508 | 12 | 7370502 | PEX5 | ENSG00000139197.6 | 1.427E-7 | 0.01 | 29221 | gtex_brain_ba24 |
| RS7969635 | 12 | 7370612 | PEX5 | ENSG00000139197.6 | 1.427E-7 | 0.01 | 29331 | gtex_brain_ba24 |
| rs7969751 | 12 | 7370702 | PEX5 | ENSG00000139197.6 | 1.423E-7 | 0.01 | 29421 | gtex_brain_ba24 |
| RS7962917 | 12 | 7317194 | PEX5 | ENSG00000139197.6 | 1.276E-8 | 0 | -24087 | gtex_brain_putamen_basal |
| RS1450962 | 12 | 7320545 | PEX5 | ENSG00000139197.6 | 2.133E-10 | 0 | -20736 | gtex_brain_putamen_basal |
| rs12828040 | 12 | 7326541 | PEX5 | ENSG00000139197.6 | 1.997E-10 | 0 | -14740 | gtex_brain_putamen_basal |
| RS7310539 | 12 | 7329996 | PEX5 | ENSG00000139197.6 | 2.435E-10 | 0 | -11285 | gtex_brain_putamen_basal |
| RS111377129 | 12 | 7331606 | PEX5 | ENSG00000139197.6 | 1.413E-6 | 0 | -9675 | gtex_brain_putamen_basal |
| RS1839622 | 12 | 7334534 | PEX5 | ENSG00000139197.6 | 2.247E-10 | 0 | -6747 | gtex_brain_putamen_basal |
| RS7973719 | 12 | 7334813 | PEX5 | ENSG00000139197.6 | 6.325e-10 | 0 | -6468 | gtex_brain_putamen_basal |
| RS12828421 | 12 | 7335217 | PEX5 | ENSG00000139197.6 | 2.079E-10 | 0 | -6064 | gtex_brain_putamen_basal |
| RS12816419 | 12 | 7335420 | PEX5 | ENSG00000139197.6 | 6.331E-10 | 0 | -5861 | gtex_brain_putamen_basal |
| RS397742110 | 12 | 7336926 | PEX5 | ENSG00000139197.6 | 5.252E-10 | 0 | -4355 | gtex_brain_putamen_basal |
| rs397851127 | 12 | 7338793 | PEX5 | ENSG00000139197.6 | 9.714e-9 | 0 | -2488 | gtex_brain_putamen_basal |
| RS61917955 | 12 | 7338947 | PEX5 | ENSG00000139197.6 | 1.839E-10 | 0 | -2334 | gtex_brain_putamen_basal |
| RS12227917 | 12 | 7342343 | PEX5 | ENSG00000139197.6 | 2.655E-10 | 0 | 1062 | gtex_brain_putamen_basal |
| rs200807978 | 12 | 7342364 | PEX5 | ENSG00000139197.6 | 3.05E-9 | 0 | 1083 | gtex_brain_putamen_basal |
| rs201786247 | 12 | 7342367 | PEX5 | ENSG00000139197.6 | 1.249E-6 | 0 | 1086 | gtex_brain_putamen_basal |
| rs200032511 | 12 | 7342371 | PEX5 | ENSG00000139197.6 | 6.54e-7 | 0 | 1090 | gtex_brain_putamen_basal |
| rs12424618 | 12 | 7344802 | PEX5 | ENSG00000139197.6 | 1.258E-11 | 0 | 3521 | gtex_brain_putamen_basal |
| RS2053887 | 12 | 7346530 | PEX5 | ENSG00000139197.6 | 4.144e-12 | 0 | 5249 | gtex_brain_putamen_basal |
| RS12830671 | 12 | 7347278 | PEX5 | ENSG00000139197.6 | 2.807E-12 | 0 | 5997 | gtex_brain_putamen_basal |
| rs12820829 | 12 | 7347534 | PEX5 | ENSG00000139197.6 | 2.799E-12 | 0 | 6253 | gtex_brain_putamen_basal |
| RS61917956 | 12 | 7348659 | PEX5 | ENSG00000139197.6 | 3.767e-12 | 0 | 7378 | gtex_brain_putamen_basal |
| rs78613188 | 12 | 7348728 | PEX5 | ENSG00000139197.6 | 1.218e-11 | 0 | 7447 | gtex_brain_putamen_basal |
| RS200897876 | 12 | 7348841 | PEX5 | ENSG00000139197.6 | 1.086E-8 | 0 | 7560 | gtex_brain_putamen_basal |
| rs200264446 | 12 | 7348912 | PEX5 | ENSG00000139197.6 | 2.823e-7 | 0 | 7631 | gtex_brain_putamen_basal |
| rs181450002 | 12 | 7349108 | PEX5 | ENSG00000139197.6 | 1.562E-8 | 0 | 7827 | gtex_brain_putamen_basal |
| rs186088555 | 12 | 7349135 | PEX5 | ENSG00000139197.6 | 3.921E-7 | 0 | 7854 | gtex_brain_putamen_basal |
| rs183222544 | 12 | 7349162 | PEX5 | ENSG00000139197.6 | 1.979E-9 | 0 | 7881 | gtex_brain_putamen_basal |
| RS61917957 | 12 | 7349987 | PEX5 | ENSG00000139197.6 | 2.169E-9 | 0 | 8706 | gtex_brain_putamen_basal |
| RS71067161 | 12 | 7350013 | PEX5 | ENSG00000139197.6 | 7.964E-10 | 0 | 8732 | gtex_brain_putamen_basal |
| RS117028872 | 12 | 7350028 | PEX5 | ENSG00000139197.6 | 1.328E-6 | 0 | 8747 | gtex_brain_putamen_basal |
| RS79081846 | 12 | 7350052 | PEX5 | ENSG00000139197.6 | 9.669E-10 | 0 | 8771 | gtex_brain_putamen_basal |
| rs200609395 | 12 | 7350135 | PEX5 | ENSG00000139197.6 | 3.462E-8 | 0 | 8854 | gtex_brain_putamen_basal |
| RS185073397 | 12 | 7350136 | PEX5 | ENSG00000139197.6 | 5.01E-7 | 0 | 8855 | gtex_brain_putamen_basal |
| RS7139158 | 12 | 7350155 | PEX5 | ENSG00000139197.6 | 2.458e-8 | 0 | 8874 | gtex_brain_putamen_basal |
| RS78964892 | 12 | 7352735 | PEX5 | ENSG00000139197.6 | 6.008平台以及 | 0 | 11454 | gtex_brain_putamen_basal |
| rs138686752 | 12 | 7352903 | PEX5 | ENSG00000139197.6 | 2.405E-12 | 0 | 11622 | gtex_brain_putamen_basal |
| RS7973600 | 12 | 7353351 | PEX5 | ENSG00000139197.6 | 6.853E-14 | 0 | 12070 | gtex_brain_putamen_basal |
| rs7962563 | 12 | 7353514 | PEX5 | ENSG00000139197.6 | 1.329E-13 | 0 | 12233 | gtex_brain_putamen_basal |
| rs10743271 | 12 | 7353790 | PEX5 | ENSG00000139197.6 | 2.402E-10 | 0 | 12509 | gtex_brain_putamen_basal |
| rs7315553 | 12 | 7353838 | PEX5 | ENSG00000139197.6 | 1.455E-13 | 0 | 12557 | gtex_brain_putamen_basal |
| rs12825629 | 12 | 7355583 | PEX5 | ENSG00000139197.6 | 1.005E-13 | 0 | 14302 | gtex_brain_putamen_basal |
| RS6486910 | 12 | 7356479 | PEX5 | ENSG00000139197.6 | 1.906E-13 | 0 | 15198 | gtex_brain_putamen_basal |
| RS6486911 | 12 | 7356494 | PEX5 | ENSG00000139197.6 | 1.904e-13 | 0 | 15213 | gtex_brain_putamen_basal |
| rs372666240 | 12 | 7356574 | PEX5 | ENSG00000139197.6 | 1.163E-6 | 0 | 15293 | gtex_brain_putamen_basal |
| rs7970916 | 12 | 7357746 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 16465 | gtex_brain_putamen_basal |
| rs75912799 | 12 | 7357897 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 16616 | gtex_brain_putamen_basal |
| rs10161405 | 12 | 7358646 | PEX5 | ENSG00000139197.6 | 5.601E-8 | 0 | 17365 | gtex_brain_putamen_basal |
| rs10161542 | 12 | 7358684 | PEX5 | ENSG00000139197.6 | 5.601E-8 | 0 | 17403 | gtex_brain_putamen_basal |
| RS11044332 | 12 | 7358768 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 17487 | gtex_brain_putamen_basal |
| RS111408486 | 12 | 7359175 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 17894 | gtex_brain_putamen_basal |
| rs397737333 | 12 | 7359309 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 18028 | gtex_brain_putamen_basal |
| RS3825405 | 12 | 7360143 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 18862 | gtex_brain_putamen_basal |
| rs3816424 | 12 | 7360229 | PEX5 | ENSG00000139197.6 | 6.524E-10 | 0 | 18948 | gtex_brain_putamen_basal |
| RS1057225 | 12 | 7363574 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 22293 | gtex_brain_putamen_basal |
| rs11448434 | 12 | 7363943 | PEX5 | ENSG00000139197.6 | 1.995E-9 | 0 | 22662 | gtex_brain_putamen_basal |
| rs4329748 | 12 | 7364442 | PEX5 | ENSG00000139197.6 | 1.449E-13 | 0 | 23161 | gtex_brain_putamen_basal |
| RS4512930 | 12 | 7364623 | PEX5 | ENSG00000139197.6 | 2.205E-13 | 0 | 23342 | gtex_brain_putamen_basal |
| rs4492891 | 12 | 7364789 | PEX5 | ENSG00000139197.6 | 1.454e-13 | 0 | 23508 | gtex_brain_putamen_basal |
| RS200081407 | 12 | 7366581 | PEX5 | ENSG00000139197.6 | 1.143E-9 | 0 | 25300 | gtex_brain_putamen_basal |
| RS12228393 | 12 | 7368182 | PEX5 | ENSG00000139197.6 | 2.807E-12 | 0 | 26901 | gtex_brain_putamen_basal |
| RS10161170 | 12 | 7368629 | PEX5 | ENSG00000139197.6 | 6.543E-10 | 0 | 27348 | gtex_brain_putamen_basal |
| rs11044901 | 12 | 7368691 | PEX5 | ENSG00000139197.6 | 6.612E-10 | 0 | 27410 | gtex_brain_putamen_basal |
| rs10161103 | 12 | 7369087 | PEX5 | ENSG00000139197.6 | 6.524E-10 | 0 | 27806 | gtex_brain_putamen_basal |
| RS397830029 | 12 | 7369169 | PEX5 | ENSG00000139197.6 | 1.22E-12 | 0 | 27888 | gtex_brain_putamen_basal |
| RS6487053 | 12 | 7369318 | PEX5 | ENSG00000139197.6 | 1.275e-12 | 0 | 28037 | gtex_brain_putamen_basal |
| RS61919598 | 12 | 7370116 | PEX5 | ENSG00000139197.6 | 5.956E-7 | 0 | 28835 | gtex_brain_putamen_basal |
| RS7969508 | 12 | 7370502 | PEX5 | ENSG00000139197.6 | 7.99e-10 | 0 | 29221 | gtex_brain_putamen_basal |
| RS7969635 | 12 | 7370612 | PEX5 | ENSG00000139197.6 | 7.99e-10 | 0 | 29331 | gtex_brain_putamen_basal |
| rs7969751 | 12 | 7370702 | PEX5 | ENSG00000139197.6 | 8E-10 | 0 | 29421 | gtex_brain_putamen_basal |
| rs72098838 | 12 | 7371483 | PEX5 | ENSG00000139197.6 | 2.216E-7 | 0 | 30202 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
基因ral gene expression (GTEx)
Devlopment期间的基因表达（BrainCloud）
脚注：
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。
基因expression of temporal and spatial changes (BrainSpan)
脚注：
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| 前10个积极共表达的基因 | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| ATAD1 | 0.93 | 0.91 |
| SLC30A9 | 0.92 | 0.91 |
| RAB18 | 0.92 | 0.92 |
| CUL2 | 0.92 | 0.89 |
| STX12 | 0.92 | 0.91 |
| FAM49B | 0.92 | 0.90 |
| USP33 | 0.92 | 0.90 |
| C10orf88 | 0.91 | 0.90 |
| PPP2CA | 0.91 | 0.89 |
| CCDC132 | 0.91 | 0.89 |
| 前10个负共表达基因 | ||
| 基因 | 皮尔逊的相关性 | 斯皮尔曼的相关性 |
| MT-CO2 | -0.74 | -0.68 |
| AF347015.33 | -0.72 | -0.66 |
| AF347015.8 | -0.71 | -0.67 |
| MT-CYB | -0.71 | -0.66 |
| FXYD1 | -0.71 | -0.68 |
| AF347015.2 | -0.71 | -0.65 |
| AF347015.26 | -0.71 | -0.66 |
| higd1b | -0.69 | -0.64 |
| AF347015.31 | -0.69 | -0.65 |
| AF347015.21 | -0.69 | -0.60 |
Section III. Gene Ontology annotation
| Molecular function | 去的术语 | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005515 | protein binding | 新闻学会 | 9653144|10837480 | |
| Biological process | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| 去：0001764 | neuron migration | IEA | neuron (GO term level: 8) | - |
| GO：0021895 | cerebral cortex neuron differentiation | IEA | neuron, Brain (GO term level: 9) | - |
| GO:0000038 | very-long-chain fatty acid metabolic process | IEA | - | |
| 去：0007006 | 线粒体膜组织 | IEA | - | |
| GO:0048468 | 细胞发育 | IEA | - | |
| 去：0007031 | 过氧化物酶体组织 | IEA | - | |
| 去：0007029 | 内质网 | IEA | - | |
| GO:0006635 | 脂肪酸β-氧化 | IEA | - | |
| GO:0015031 | protein transport | IEA | - | |
| GO:0040018 | 多细胞生物生长的阳性调节 | IEA | - | |
| GO：0021795 | cerebral cortex cell migration | IEA | - | |
| GO：0044255 | cellular lipid metabolic process | IEA | - | |
| GO：0050905 | neuromuscular process | IEA | - | |
| 细胞分量 | 去的术语 | Evidence | Neuro keywords | PubMed ID |
| GO:0005737 | 细胞质 | IEA | - | |
| GO:0005777 | 过氧化物酶体 | IEA | - | |
| GO:0005778 | peroxisomal membrane | IEA | - | |
| GO:0016020 | 膜 | IEA | - |
第四节。蛋白质蛋白相互作用注释
| Interactors | Aliases B | Official full name B | Experimental | 资源 | PubMed ID |
|---|---|---|---|---|---|
| ATM | AT1 |ata |ATC |ATD |ATDC |吃饭|DKFZP781A0353 |MGC74674 |Tel1 |Telo1 | 毛细血管炎突变 | - | HPRD，Biogrid | 10567403 |
| 猫 | MGC138422 |MGC138424 | 过氧化氢酶 | 两个杂交 | BioGRID | 10567403 |
| DDO | Dasox |DDO-1 |DDO-2 |FLJ45203 | D-天冬氨酸氧化酶 | - | HPRD，Biogrid | 9820813 |
| HSPA1A | FLJ54303 |FLJ54370 |FLJ54392 |FLJ54408 |FLJ75127 |HSP70-1 |HSP70-1A |HSP70I |HSP72 |HSPA1 | HSPA1B | heat shock 70kDa protein 1A | - | HPRD | 11415446 |
| PDZK1 | CAP70 |夹具|nherf3 |PDZD1 | PDZ domain containing 1 | 两个杂交 | BioGRID | 16189514 |
| PEX10 | MGC1998 |纳尔德|RNF69 | peroxisomal biogenesis factor 10 | - | HPRD，Biogrid | 10837480 |
| PEX12 | PAF-3 | peroxisomal biogenesis factor 12 | PEX12与PEX5相互作用。 | BIND | 12096124 |
| PEX12 | PAF-3 | peroxisomal biogenesis factor 12 | - | HPRD，Biogrid | 10562279|10837480 |
| PEX13 | 纳尔德|ZWS | peroxisomal biogenesis factor 13 | - | HPRD，Biogrid | 8858165|11865044 |
| PEX14 | MGC12767 |napp2 |PEX14P |DJ734G22.2 | peroxisomal biogenesis factor 14 | PEX14interacts with PEX5. | BIND | 12096124 |
| PEX14 | MGC12767 |napp2 |PEX14P |DJ734G22.2 | peroxisomal biogenesis factor 14 | Reconstituted Complex 两个杂交 |
BioGRID | 10212238|10837480 |11865044 |
| PEX14 | MGC12767 |napp2 |PEX14P |DJ734G22.2 | peroxisomal biogenesis factor 14 | - | HPRD | 10212238|11865044 |
| PEX7 | pts2r |RCDP1 |路 | peroxisomal biogenesis factor 7 | - | HPRD，Biogrid | 11546814|11865044 |
| pxmp3 | PAF-1 |PAF1 |PEX2 |PMP3 |PMP35 |RNF72 | 过氧化物酶体膜蛋白3，35KDA | - | HPRD | 10837480 |
| SIRT3 | sir2l3 | Sirtuin（无声交配类型信息法规2同源物）3（S. cerevisiae） | 两个杂交 | BioGRID | 16189514 |
| SNUPN | kpnbl |rnut1 |Snurportin1 | snurportin 1 | 两个杂交 | BioGRID | 16169070 |
V.途径注释
| Pathway name | Pathway size | ＃szgr 2.0基因 | Info |
|---|---|---|---|
| kegg过氧化物酶体 | 78 | 47 | 该途径中的所有SZGR 2.0基因 |
| 家长mtor信号向上 | 567 | 375 | 该途径中的所有SZGR 2.0基因 |
| Onken紫菜叶黑色素瘤DN | 526 | 357 | 该途径中的所有SZGR 2.0基因 |
| Doane对雄激素DN的反应 | 241 | 146 | 该途径中的所有SZGR 2.0基因 |
| LAIHO COLORECTAL CANCER SERRATED DN | 86 | 47 | 该途径中的所有SZGR 2.0基因 |
| Gal白血病干细胞向上 | 133 | 78 | 该途径中的所有SZGR 2.0基因 |
| Rashi对电离辐射5的响应5 | 147 | 89 | 该途径中的所有SZGR 2.0基因 |
| PUJANA BREAST CANCER LIT INT NETWORK | 101 | 73 | 该途径中的所有SZGR 2.0基因 |
| PUJANA BRCA1 PCC NETWORK | 1652 | 1023 | 该途径中的所有SZGR 2.0基因 |
| SCHAEFFER PROSTATE DEVELOPMENT 6HR DN | 514 | 330 | 该途径中的所有SZGR 2.0基因 |
| BYSTRYKH造血干细胞QTL Trans | 882 | 572 | 该途径中的所有SZGR 2.0基因 |
| ZHAN V2 LATE DIFFERENTIATION GENES | 45 | 34 | 该途径中的所有SZGR 2.0基因 |
| Lee Calorie限制肌肉 | 43 | 33 | 该途径中的所有SZGR 2.0基因 |
| KRIGE RESPONSE TO TOSEDOSTAT 6HR DN | 911 | 527 | 该途径中的所有SZGR 2.0基因 |
| KRIGE RESPONSE TO TOSEDOSTAT 24HR DN | 1011 | 592 | 该途径中的所有SZGR 2.0基因 |
| Yoshioka肝癌早期复发 | 40 | 23 | 该途径中的所有SZGR 2.0基因 |
| Acosta增殖独立MYC靶向 | 84 | 51 | 该途径中的所有SZGR 2.0基因 |
| TERAO AOX4靶向HG | 28 | 20 | 该途径中的所有SZGR 2.0基因 |
| GOBERT OLIGODENDROCYTE DIFFERENTIATION DN | 1080 | 713 | 该途径中的所有SZGR 2.0基因 |
| wakabayashi脂肪生成PPARG RXRA绑定8D | 882 | 506 | 该途径中的所有SZGR 2.0基因 |
| wakabayashi脂肪形成PPARG RXRA与H4K20me1标记结合 | 145 | 82 | 该途径中的所有SZGR 2.0基因 |
| Alfano MYC目标 | 239 | 156 | 该途径中的所有SZGR 2.0基因 |
第六节。microRNA注释
| miRNA family | 目标位置 | mirna id | miRNA seq | ||
|---|---|---|---|---|---|
| UTR start | UTR end | Match method | |||
| mir-141/200a | 919 | 926 | 1A,m8 | hsa-miR-141 | UAACACUGUCUGGUAAAGAUGG |
| HSA-MIR-200A | uaacacugucuguguguguaaacgaugu | ||||
| mir-15/16/195/424/497 | 272 | 278 | m8 | hsa-miR-15a脑 | UAGCAGCACAUAAUGGUUUGUG |
| HSA-MIR-16脑 | uagcagcacguaaauauuggcg | ||||
| hsa-miR-15b脑 | uagcagcacaucaugguuaca | ||||
| hsa-miR-195SZ | UAGCAGCACAGAAAUAUUGGC | ||||
| HSA-MIR-424 | Cagcagcaauucauguuuugaa | ||||
| hsa-miR-497 | CAGCAGCACACUGUGGUUUGU | ||||
| mir-29 | 269 | 275 | m8 | hsa-miR-29aSZ | uagcaccaucugaaaucgguu |
| hsa-miR-29bSZ | uagcaccauuugaaaucaguguu | ||||
| hsa-miR-29cSZ | uagcaccauuugaaaucggu | ||||
| mir-31 | 892 | 899 | 1A,m8 | HSA-MIR-31 | AGGCAAGAUGCUGGCAUAGCUG |
| mir-361 | 330 | 336 | m8 | hsa-miR-361脑 | UUAUCAGAAUCUCCAGGGGUAC |