Summary?
GeneID 58485
Symbol TRAPPC1
Synonyms BET5|MUM2
Description trafficking protein particle complex 1
Reference MIM:610969|HGNC:HGNC:19894|Ensembl:ENSG00000170043|HPRD:18219|Vega:OTTHUMG00000108171
Gene type protein-coding
Map location 17p13.1
Pascal p-value 0.013
Sherlock p-value 0.005
Fetal beta -0.567

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
PRDX6 0.85 0.77
RLBP1 0.84 0.70
LGALS3 0.83 0.72
NQO1 0.83 0.79
BAALC 0.81 0.72
GJB6 0.80 0.69
PSMB8 0.80 0.71
SAT1 0.80 0.70
TLCD1 0.80 0.76
NDRG2 0.80 0.74
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
UPF2 -0.64 -0.68
ZNF407 -0.63 -0.71
RTF1 -0.63 -0.71
SUPT6H -0.63 -0.70
BRD4 -0.63 -0.72
NCOR1 -0.62 -0.69
GIGYF2 -0.62 -0.69
ANKRD17 -0.62 -0.67
TCOF1 -0.62 -0.67
C14orf102 -0.62 -0.68

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
CHANDRAN METASTASIS TOP50 DN 45 26 All SZGR 2.0 genes in this pathway
LASTOWSKA神经母细胞瘤拷贝数 181 108 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS DN 261 155 All SZGR 2.0 genes in this pathway
NOUZOVA TRETINOIN AND H4 ACETYLATION 143 85 All SZGR 2.0 genes in this pathway
JIANG HYPOXIA CANCER 83 52 All SZGR 2.0 genes in this pathway
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION UP 64 40 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 UNSTIMULATED 1229 713 All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE 346 192 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306 191 All SZGR 2.0 genes in this pathway
CHICAS RB1 TARGETS CONFLUENT 567 365 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 3 UP 170 97 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 4 UP 112 64 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 6 UP 140 81 All SZGR 2.0 genes in this pathway
FIGUEROA AML METHYLATION CLUSTER 7 UP 118 68 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 2 UP 140 94 All SZGR 2.0 genes in this pathway