Gene Page:PRPH2
Summary?
| GeneID | 5961 |
| Symbol | PRPH2 |
| Synonyms | AOFMD|AVMD|CACD2|DS|MDBS1|PRPH|RDS|RP7|TSPAN22|rd2 |
| Description | peripherin 2 (retinal degeneration, slow) |
| Reference | MIM:179605|HGNC:HGNC:9942|Ensembl:ENSG00000112619|HPRD:01553|Vega:OTTHUMG00000014701 |
| Gene type | protein-coding |
| Map location | 6p21.1 |
| Pascal p-value | 0.006 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS | |
| GSMA_I | Genome scan meta-analysis | Psr: 0.033 | |
| GSMA_IIE | Genome scan meta-analysis (European-ancestry samples) | Psr: 0.04433 |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6938784 | chr6 | 42490521 | PRPH2 | 5961 | 0.04 | cis | ||
| rs17287873 | chr6 | 42572858 | PRPH2 | 5961 | 0.07 | cis | ||
| rs9296394 | chr6 | 42587817 | PRPH2 | 5961 | 1.189E-8 | cis | ||
| rs9367160 | chr6 | 42618489 | PRPH2 | 5961 | 4.752E-9 | cis | ||
| rs6905797 | chr6 | 42642922 | PRPH2 | 5961 | 4.398E-9 | cis | ||
| rs11754813 | chr6 | 42690513 | PRPH2 | 5961 | 0.06 | cis | ||
| rs10515928 | chr2 | 160074898 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs9287785 | chr2 | 160075008 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs10490004 | chr2 | 160076139 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs11903200 | chr2 | 160076308 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs2241023 | chr2 | 160081335 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs10490003 | chr2 | 160082889 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs3815475 | chr2 | 160114314 | PRPH2 | 5961 | 0 | trans | ||
| rs10189317 | chr2 | 160123106 | PRPH2 | 5961 | 8.183E-5 | trans | ||
| rs8179587 | chr2 | 160187588 | PRPH2 | 5961 | 6.512E-6 | trans | ||
| rs3755433 | chr2 | 160269002 | PRPH2 | 5961 | 0 | trans | ||
| rs9296394 | chr6 | 42587817 | PRPH2 | 5961 | 2.833E-6 | trans | ||
| rs9367160 | chr6 | 42618489 | PRPH2 | 5961 | 1.163E-6 | trans | ||
| rs6905797 | chr6 | 42642922 | PRPH2 | 5961 | 1.072E-6 | trans | ||
| rs2460559 | chr10 | 43855479 | PRPH2 | 5961 | 0.03 | trans | ||
| rs987035 | chr13 | 106274330 | PRPH2 | 5961 | 0.02 | trans | ||
| rs16967008 | chr13 | 106287437 | PRPH2 | 5961 | 0.05 | trans | ||
| rs16956956 | chr15 | 72743457 | PRPH2 | 5961 | 0.05 | trans | ||
| rs8038734 | chr15 | 72811401 | PRPH2 | 5961 | 0.17 | trans | ||
| rs373476 | chr16 | 86774323 | PRPH2 | 5961 | 0.16 | trans | ||
| rs728659 | chr18 | 24303971 | PRPH2 | 5961 | 0.19 | trans | ||
| rs9961391 | chr18 | 74036094 | PRPH2 | 5961 | 0.04 | trans | ||
| rs6032025 | chr20 | 43775001 | PRPH2 | 5961 | 0.01 | trans | ||
| rs7767359 | 6 | 42480131 | PRPH2 | ENSG00000112619.6 | 4.808E-8 | 0 | 210181 | gtex_brain_ba24 |
| rs9471875 | 6 | 42480344 | PRPH2 | ENSG00000112619.6 | 3.908E-7 | 0 | 209968 | gtex_brain_ba24 |
| rs7752212 | 6 | 42480932 | PRPH2 | ENSG00000112619.6 | 3.173E-6 | 0 | 209380 | gtex_brain_ba24 |
| rs7752219 | 6 | 42480934 | PRPH2 | ENSG00000112619.6 | 3.166E-6 | 0 | 209378 | gtex_brain_ba24 |
| rs9394903 | 6 | 42486084 | PRPH2 | ENSG00000112619.6 | 3.369E-10 | 0 | 204228 | gtex_brain_ba24 |
| rs6458283 | 6 | 42487163 | PRPH2 | ENSG00000112619.6 | 2.171E-6 | 0 | 203149 | gtex_brain_ba24 |
| rs6919841 | 6 | 42487309 | PRPH2 | ENSG00000112619.6 | 2.162E-6 | 0 | 203003 | gtex_brain_ba24 |
| rs7749835 | 6 | 42489491 | PRPH2 | ENSG00000112619.6 | 2.066E-6 | 0 | 200821 | gtex_brain_ba24 |
| rs6938784 | 6 | 42490522 | PRPH2 | ENSG00000112619.6 | 2E-6 | 0 | 199790 | gtex_brain_ba24 |
| rs59340074 | 6 | 42492167 | PRPH2 | ENSG00000112619.6 | 2.161E-6 | 0 | 198145 | gtex_brain_ba24 |
| rs59491926 | 6 | 42494724 | PRPH2 | ENSG00000112619.6 | 1.508E-6 | 0 | 195588 | gtex_brain_ba24 |
| rs10707503 | 6 | 42497148 | PRPH2 | ENSG00000112619.6 | 2.851E-6 | 0 | 193164 | gtex_brain_ba24 |
| rs9296387 | 6 | 42502314 | PRPH2 | ENSG00000112619.6 | 5.559E-9 | 0 | 187998 | gtex_brain_ba24 |
| rs1810669 | 6 | 42503621 | PRPH2 | ENSG00000112619.6 | 6.895E-9 | 0 | 186691 | gtex_brain_ba24 |
| rs7769374 | 6 | 42504963 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 185349 | gtex_brain_ba24 |
| rs9367151 | 6 | 42505103 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 185209 | gtex_brain_ba24 |
| rs9381188 | 6 | 42505116 | PRPH2 | ENSG00000112619.6 | 5.559E-9 | 0 | 185196 | gtex_brain_ba24 |
| rs9381189 | 6 | 42505139 | PRPH2 | ENSG00000112619.6 | 3.059E-6 | 0 | 185173 | gtex_brain_ba24 |
| rs4711722 | 6 | 42505551 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 184761 | gtex_brain_ba24 |
| rs4711723 | 6 | 42505811 | PRPH2 | ENSG00000112619.6 | 3.608E-6 | 0 | 184501 | gtex_brain_ba24 |
| rs4711724 | 6 | 42506378 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 183934 | gtex_brain_ba24 |
| rs11755553 | 6 | 42506457 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 183855 | gtex_brain_ba24 |
| rs11758022 | 6 | 42506577 | PRPH2 | ENSG00000112619.6 | 5.559E-9 | 0 | 183735 | gtex_brain_ba24 |
| rs9462807 | 6 | 42506864 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 183448 | gtex_brain_ba24 |
| rs9471876 | 6 | 42506889 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 183423 | gtex_brain_ba24 |
| rs9462808 | 6 | 42507004 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 183308 | gtex_brain_ba24 |
| rs9369365 | 6 | 42507445 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 182867 | gtex_brain_ba24 |
| rs9367152 | 6 | 42507556 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 182756 | gtex_brain_ba24 |
| rs6458285 | 6 | 42507839 | PRPH2 | ENSG00000112619.6 | 3.595E-6 | 0 | 182473 | gtex_brain_ba24 |
| rs6458286 | 6 | 42507887 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 182425 | gtex_brain_ba24 |
| rs6458288 | 6 | 42508329 | PRPH2 | ENSG00000112619.6 | 3.032E-6 | 0 | 181983 | gtex_brain_ba24 |
| rs6458289 | 6 | 42508437 | PRPH2 | ENSG00000112619.6 | 3.594E-6 | 0 | 181875 | gtex_brain_ba24 |
| rs7758705 | 6 | 42510251 | PRPH2 | ENSG00000112619.6 | 3.026E-6 | 0 | 180061 | gtex_brain_ba24 |
| rs7758850 | 6 | 42510301 | PRPH2 | ENSG00000112619.6 | 2.748E-6 | 0 | 180011 | gtex_brain_ba24 |
| rs397977027 | 6 | 42511740 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 178572 | gtex_brain_ba24 |
| rs6934696 | 6 | 42512396 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 177916 | gtex_brain_ba24 |
| rs4263587 | 6 | 42513047 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 177265 | gtex_brain_ba24 |
| rs9381191 | 6 | 42513111 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 177201 | gtex_brain_ba24 |
| rs9369369 | 6 | 42513435 | PRPH2 | ENSG00000112619.6 | 4.36E-9 | 0 | 176877 | gtex_brain_ba24 |
| rs6458291 | 6 | 42513779 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 176533 | gtex_brain_ba24 |
| rs7751714 | 6 | 42514332 | PRPH2 | ENSG00000112619.6 | 3.866E-7 | 0 | 175980 | gtex_brain_ba24 |
| rs767160 | 6 | 42514688 | PRPH2 | ENSG00000112619.6 | 3.035E-6 | 0 | 175624 | gtex_brain_ba24 |
| rs9349235 | 6 | 42516718 | PRPH2 | ENSG00000112619.6 | 9.116E-7 | 0 | 173594 | gtex_brain_ba24 |
| rs11759298 | 6 | 42517566 | PRPH2 | ENSG00000112619.6 | 9.116E-7 | 0 | 172746 | gtex_brain_ba24 |
| rs9381192 | 6 | 42518706 | PRPH2 | ENSG00000112619.6 | 5.354E-11 | 0 | 171606 | gtex_brain_ba24 |
| rs55898675 | 6 | 42520396 | PRPH2 | ENSG00000112619.6 | 9.441E-7 | 0 | 169916 | gtex_brain_ba24 |
| rs201247280 | 6 | 42521088 | PRPH2 | ENSG00000112619.6 | 6.3E-8 | 0 | 169224 | gtex_brain_ba24 |
| rs9462809 | 6 | 42521143 | PRPH2 | ENSG00000112619.6 | 9.535E-7 | 0 | 169169 | gtex_brain_ba24 |
| rs6458294 | 6 | 42522412 | PRPH2 | ENSG00000112619.6 | 2.654E-7 | 0 | 167900 | gtex_brain_ba24 |
| rs6458295 | 6 | 42522523 | PRPH2 | ENSG00000112619.6 | 9.691E-7 | 0 | 167789 | gtex_brain_ba24 |
| rs9296388 | 6 | 42524552 | PRPH2 | ENSG00000112619.6 | 4.041E-7 | 0 | 165760 | gtex_brain_ba24 |
| rs9296389 | 6 | 42524937 | PRPH2 | ENSG00000112619.6 | 1E-6 | 0 | 165375 | gtex_brain_ba24 |
| rs9296390 | 6 | 42524963 | PRPH2 | ENSG00000112619.6 | 1E-6 | 0 | 165349 | gtex_brain_ba24 |
| rs6911657 | 6 | 42525949 | PRPH2 | ENSG00000112619.6 | 1.002E-6 | 0 | 164363 | gtex_brain_ba24 |
| rs10085253 | 6 | 42526622 | PRPH2 | ENSG00000112619.6 | 1.008E-6 | 0 | 163690 | gtex_brain_ba24 |
| rs4499930 | 6 | 42527706 | PRPH2 | ENSG00000112619.6 | 9.293E-13 | 0 | 162606 | gtex_brain_ba24 |
| rs9394908 | 6 | 42527902 | PRPH2 | ENSG00000112619.6 | 1.011E-6 | 0 | 162410 | gtex_brain_ba24 |
| rs6909728 | 6 | 42528945 | PRPH2 | ENSG00000112619.6 | 1.013E-6 | 0 | 161367 | gtex_brain_ba24 |
| rs9381194 | 6 | 42530004 | PRPH2 | ENSG00000112619.6 | 1.014E-6 | 0 | 160308 | gtex_brain_ba24 |
| rs6900726 | 6 | 42531650 | PRPH2 | ENSG00000112619.6 | 9.228E-13 | 0 | 158662 | gtex_brain_ba24 |
| rs3749897 | 6 | 42532102 | PRPH2 | ENSG00000112619.6 | 1.014E-6 | 0 | 158210 | gtex_brain_ba24 |
| rs2181331 | 6 | 42534391 | PRPH2 | ENSG00000112619.6 | 2.743E-7 | 0 | 155921 | gtex_brain_ba24 |
| rs7751587 | 6 | 42535129 | PRPH2 | ENSG00000112619.6 | 3.121E-6 | 0 | 155183 | gtex_brain_ba24 |
| rs7762500 | 6 | 42537205 | PRPH2 | ENSG00000112619.6 | 1.01E-6 | 0 | 153107 | gtex_brain_ba24 |
| rs57290849 | 6 | 42540230 | PRPH2 | ENSG00000112619.6 | 1.029E-12 | 0 | 150082 | gtex_brain_ba24 |
| rs6920844 | 6 | 42545638 | PRPH2 | ENSG00000112619.6 | 1.176E-7 | 0 | 144674 | gtex_brain_ba24 |
| rs9462810 | 6 | 42546840 | PRPH2 | ENSG00000112619.6 | 5.314E-8 | 0 | 143472 | gtex_brain_ba24 |
| rs6458297 | 6 | 42547891 | PRPH2 | ENSG00000112619.6 | 8.887E-13 | 0 | 142421 | gtex_brain_ba24 |
| rs2181332 | 6 | 42551232 | PRPH2 | ENSG00000112619.6 | 5.314E-8 | 0 | 139080 | gtex_brain_ba24 |
| rs9394910 | 6 | 42555254 | PRPH2 | ENSG00000112619.6 | 8.882E-13 | 0 | 135058 | gtex_brain_ba24 |
| rs9394911 | 6 | 42562996 | PRPH2 | ENSG00000112619.6 | 2.636E-12 | 0 | 127316 | gtex_brain_ba24 |
| rs6902425 | 6 | 42563346 | PRPH2 | ENSG00000112619.6 | 8.848E-13 | 0 | 126966 | gtex_brain_ba24 |
| rs9369370 | 6 | 42565741 | PRPH2 | ENSG00000112619.6 | 1.023E-6 | 0 | 124571 | gtex_brain_ba24 |
| rs6941663 | 6 | 42566728 | PRPH2 | ENSG00000112619.6 | 1.1E-7 | 0 | 123584 | gtex_brain_ba24 |
| rs11751424 | 6 | 42567119 | PRPH2 | ENSG00000112619.6 | 5.012E-8 | 0 | 123193 | gtex_brain_ba24 |
| rs55679749 | 6 | 42568082 | PRPH2 | ENSG00000112619.6 | 1.022E-6 | 0 | 122230 | gtex_brain_ba24 |
| rs2025249 | 6 | 42568248 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 122064 | gtex_brain_ba24 |
| rs10498753 | 6 | 42571807 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 118505 | gtex_brain_ba24 |
| rs2025250 | 6 | 42572494 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 117818 | gtex_brain_ba24 |
| rs17287873 | 6 | 42572859 | PRPH2 | ENSG00000112619.6 | 1.014E-6 | 0 | 117453 | gtex_brain_ba24 |
| rs57880987 | 6 | 42573152 | PRPH2 | ENSG00000112619.6 | 1.014E-6 | 0 | 117160 | gtex_brain_ba24 |
| rs7745976 | 6 | 42573285 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 117027 | gtex_brain_ba24 |
| rs60649017 | 6 | 42575390 | PRPH2 | ENSG00000112619.6 | 3.263E-12 | 0 | 114922 | gtex_brain_ba24 |
| rs9369372 | 6 | 42575703 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 114609 | gtex_brain_ba24 |
| rs9369373 | 6 | 42575723 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 114589 | gtex_brain_ba24 |
| rs4472340 | 6 | 42580755 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 109557 | gtex_brain_ba24 |
| rs9462812 | 6 | 42581696 | PRPH2 | ENSG00000112619.6 | 9.034E-13 | 0 | 108616 | gtex_brain_ba24 |
| rs10807281 | 6 | 42582541 | PRPH2 | ENSG00000112619.6 | 8.215E-13 | 0 | 107771 | gtex_brain_ba24 |
| rs35018263 | 6 | 42582553 | PRPH2 | ENSG00000112619.6 | 3.026E-12 | 0 | 107759 | gtex_brain_ba24 |
| rs9381203 | 6 | 42583625 | PRPH2 | ENSG00000112619.6 | 9.395E-13 | 0 | 106687 | gtex_brain_ba24 |
| rs6458299 | 6 | 42586058 | PRPH2 | ENSG00000112619.6 | 1.012E-6 | 0 | 104254 | gtex_brain_ba24 |
| rs9296394 | 6 | 42587818 | PRPH2 | ENSG00000112619.6 | 9.395E-13 | 0 | 102494 | gtex_brain_ba24 |
| rs144089110 | 6 | 42588216 | PRPH2 | ENSG00000112619.6 | 1.976E-13 | 0 | 102096 | gtex_brain_ba24 |
| rs6458300 | 6 | 42589262 | PRPH2 | ENSG00000112619.6 | 9.927E-7 | 0 | 101050 | gtex_brain_ba24 |
| rs9369374 | 6 | 42589838 | PRPH2 | ENSG00000112619.6 | 7.963E-7 | 0 | 100474 | gtex_brain_ba24 |
| rs12153987 | 6 | 42589913 | PRPH2 | ENSG00000112619.6 | 9.301E-13 | 0 | 100399 | gtex_brain_ba24 |
| rs9357400 | 6 | 42591128 | PRPH2 | ENSG00000112619.6 | 9.301E-13 | 0 | 99184 | gtex_brain_ba24 |
| rs9349236 | 6 | 42591275 | PRPH2 | ENSG00000112619.6 | 1.43E-12 | 0 | 99037 | gtex_brain_ba24 |
| rs9367157 | 6 | 42591285 | PRPH2 | ENSG00000112619.6 | 1.43E-12 | 0 | 99027 | gtex_brain_ba24 |
| rs70990113 | 6 | 42591881 | PRPH2 | ENSG00000112619.6 | 1.431E-12 | 0 | 98431 | gtex_brain_ba24 |
| rs7743466 | 6 | 42592012 | PRPH2 | ENSG00000112619.6 | 1.932E-13 | 0 | 98300 | gtex_brain_ba24 |
| rs11758160 | 6 | 42593607 | PRPH2 | ENSG00000112619.6 | 9.903E-7 | 0 | 96705 | gtex_brain_ba24 |
| rs4711725 | 6 | 42594053 | PRPH2 | ENSG00000112619.6 | 1.003E-6 | 0 | 96259 | gtex_brain_ba24 |
| rs199997560 | 6 | 42594066 | PRPH2 | ENSG00000112619.6 | 1.881E-13 | 0 | 96246 | gtex_brain_ba24 |
| rs36072475 | 6 | 42594068 | PRPH2 | ENSG00000112619.6 | 1.881E-13 | 0 | 96244 | gtex_brain_ba24 |
| rs12529803 | 6 | 42595047 | PRPH2 | ENSG00000112619.6 | 9.275E-13 | 0 | 95265 | gtex_brain_ba24 |
| rs7741465 | 6 | 42597065 | PRPH2 | ENSG00000112619.6 | 1.019E-6 | 0 | 93247 | gtex_brain_ba24 |
| rs7773898 | 6 | 42599673 | PRPH2 | ENSG00000112619.6 | 3.083E-10 | 0 | 90639 | gtex_brain_ba24 |
| rs7753593 | 6 | 42599704 | PRPH2 | ENSG00000112619.6 | 2.675E-10 | 0 | 90608 | gtex_brain_ba24 |
| rs1884086 | 6 | 42604320 | PRPH2 | ENSG00000112619.6 | 1.759E-6 | 0 | 85992 | gtex_brain_ba24 |
| rs2812674 | 6 | 42607056 | PRPH2 | ENSG00000112619.6 | 1.856E-6 | 0 | 83256 | gtex_brain_ba24 |
| rs7740672 | 6 | 42607331 | PRPH2 | ENSG00000112619.6 | 1.86E-6 | 0 | 82981 | gtex_brain_ba24 |
| rs4521584 | 6 | 42608187 | PRPH2 | ENSG00000112619.6 | 8.494E-13 | 0 | 82125 | gtex_brain_ba24 |
| rs13213476 | 6 | 42608668 | PRPH2 | ENSG00000112619.6 | 8.377E-13 | 0 | 81644 | gtex_brain_ba24 |
| rs13200782 | 6 | 42614780 | PRPH2 | ENSG00000112619.6 | 2.432E-12 | 0 | 75532 | gtex_brain_ba24 |
| rs9471891 | 6 | 42616933 | PRPH2 | ENSG00000112619.6 | 7.261E-13 | 0 | 73379 | gtex_brain_ba24 |
| rs3763234 | 6 | 42617961 | PRPH2 | ENSG00000112619.6 | 7.251E-13 | 0 | 72351 | gtex_brain_ba24 |
| rs9367160 | 6 | 42618490 | PRPH2 | ENSG00000112619.6 | 7.251E-13 | 0 | 71822 | gtex_brain_ba24 |
| rs9462815 | 6 | 42618739 | PRPH2 | ENSG00000112619.6 | 7.242E-13 | 0 | 71573 | gtex_brain_ba24 |
| rs10807282 | 6 | 42622455 | PRPH2 | ENSG00000112619.6 | 7.223E-13 | 0 | 67857 | gtex_brain_ba24 |
| rs2395922 | 6 | 42625386 | PRPH2 | ENSG00000112619.6 | 3.601E-6 | 0 | 64926 | gtex_brain_ba24 |
| rs59876630 | 6 | 42626147 | PRPH2 | ENSG00000112619.6 | 7.093E-13 | 0 | 64165 | gtex_brain_ba24 |
| rs6917033 | 6 | 42627434 | PRPH2 | ENSG00000112619.6 | 3.433E-6 | 0 | 62878 | gtex_brain_ba24 |
| rs3736745 | 6 | 42630107 | PRPH2 | ENSG00000112619.6 | 5.67E-13 | 0 | 60205 | gtex_brain_ba24 |
| rs11392975 | 6 | 42630793 | PRPH2 | ENSG00000112619.6 | 1.468E-12 | 0 | 59519 | gtex_brain_ba24 |
| rs9394913 | 6 | 42632246 | PRPH2 | ENSG00000112619.6 | 5.661E-13 | 0 | 58066 | gtex_brain_ba24 |
| rs926793 | 6 | 42638237 | PRPH2 | ENSG00000112619.6 | 3.115E-6 | 0 | 52075 | gtex_brain_ba24 |
| rs4460209 | 6 | 42638564 | PRPH2 | ENSG00000112619.6 | 3.112E-6 | 0 | 51748 | gtex_brain_ba24 |
| rs6905797 | 6 | 42642923 | PRPH2 | ENSG00000112619.6 | 5.031E-13 | 0 | 47389 | gtex_brain_ba24 |
| rs2038261 | 6 | 42644623 | PRPH2 | ENSG00000112619.6 | 2.804E-6 | 0 | 45689 | gtex_brain_ba24 |
| rs9367161 | 6 | 42653359 | PRPH2 | ENSG00000112619.6 | 5.223E-13 | 0 | 36953 | gtex_brain_ba24 |
| rs13194067 | 6 | 42655088 | PRPH2 | ENSG00000112619.6 | 5.589E-13 | 0 | 35224 | gtex_brain_ba24 |
| rs13193863 | 6 | 42655094 | PRPH2 | ENSG00000112619.6 | 5.582E-13 | 0 | 35218 | gtex_brain_ba24 |
| rs9394917 | 6 | 42660017 | PRPH2 | ENSG00000112619.6 | 5.335E-13 | 0 | 30295 | gtex_brain_ba24 |
| rs34394180 | 6 | 42660885 | PRPH2 | ENSG00000112619.6 | 3.418E-12 | 0 | 29427 | gtex_brain_ba24 |
| rs9349238 | 6 | 42663548 | PRPH2 | ENSG00000112619.6 | 4.805E-12 | 0 | 26764 | gtex_brain_ba24 |
| rs835 | 6 | 42665888 | PRPH2 | ENSG00000112619.6 | 1.225E-13 | 0 | 24424 | gtex_brain_ba24 |
| rs9471896 | 6 | 42667047 | PRPH2 | ENSG00000112619.6 | 2.841E-13 | 0 | 23265 | gtex_brain_ba24 |
| rs2268687 | 6 | 42668932 | PRPH2 | ENSG00000112619.6 | 1.726E-13 | 0 | 21380 | gtex_brain_ba24 |
| rs2268686 | 6 | 42669108 | PRPH2 | ENSG00000112619.6 | 1.689E-13 | 0 | 21204 | gtex_brain_ba24 |
| rs9381211 | 6 | 42670374 | PRPH2 | ENSG00000112619.6 | 1.418E-13 | 0 | 19938 | gtex_brain_ba24 |
| rs9394918 | 6 | 42670450 | PRPH2 | ENSG00000112619.6 | 3.119E-14 | 0 | 19862 | gtex_brain_ba24 |
| rs12333241 | 6 | 42671439 | PRPH2 | ENSG00000112619.6 | 3.18E-14 | 0 | 18873 | gtex_brain_ba24 |
| rs71765744 | 6 | 42671817 | PRPH2 | ENSG00000112619.6 | 8.225E-16 | 0 | 18495 | gtex_brain_ba24 |
| rs200767461 | 6 | 42671860 | PRPH2 | ENSG00000112619.6 | 2.74E-15 | 0 | 18452 | gtex_brain_ba24 |
| rs67162942 | 6 | 42671861 | PRPH2 | ENSG00000112619.6 | 3.22E-15 | 0 | 18451 | gtex_brain_ba24 |
| rs3818087 | 6 | 42672407 | PRPH2 | ENSG00000112619.6 | 2.241E-15 | 0 | 17905 | gtex_brain_ba24 |
| rs3818086 | 6 | 42672416 | PRPH2 | ENSG00000112619.6 | 8.483 e-8 | 0 | 17896 | gtex_brain_ba24 |
| rs34722725 | 6 | 42672434 | PRPH2 | ENSG00000112619.6 | 2.981E-15 | 0 | 17878 | gtex_brain_ba24 |
| rs13214506 | 6 | 42672574 | PRPH2 | ENSG00000112619.6 | 2.993E-15 | 0 | 17738 | gtex_brain_ba24 |
| rs12333110 | 6 | 42673107 | PRPH2 | ENSG00000112619.6 | 2.852E-15 | 0 | 17205 | gtex_brain_ba24 |
| rs9296398 | 6 | 42673678 | PRPH2 | ENSG00000112619.6 | 1.992E-8 | 0 | 16634 | gtex_brain_ba24 |
| rs58035225 | 6 | 42674318 | PRPH2 | ENSG00000112619.6 | 6.695E-8 | 0 | 15994 | gtex_brain_ba24 |
| rs397693759 | 6 | 42674345 | PRPH2 | ENSG00000112619.6 | 1.264E-7 | 0 | 15967 | gtex_brain_ba24 |
| rs67473485 | 6 | 42674631 | PRPH2 | ENSG00000112619.6 | 5.587E-15 | 0 | 15681 | gtex_brain_ba24 |
| rs9357402 | 6 | 42674983 | PRPH2 | ENSG00000112619.6 | 1.321E-7 | 0 | 15329 | gtex_brain_ba24 |
| rs7742623 | 6 | 42676307 | PRPH2 | ENSG00000112619.6 | 3.653E-8 | 0 | 14005 | gtex_brain_ba24 |
| rs9349239 | 6 | 42676480 | PRPH2 | ENSG00000112619.6 | 3.632E-8 | 0 | 13832 | gtex_brain_ba24 |
| rs9369380 | 6 | 42676511 | PRPH2 | ENSG00000112619.6 | 2.859E-8 | 0 | 13801 | gtex_brain_ba24 |
| rs9367162 | 6 | 42676827 | PRPH2 | ENSG00000112619.6 | 6.526E-15 | 0 | 13485 | gtex_brain_ba24 |
| rs9357403 | 6 | 42676932 | PRPH2 | ENSG00000112619.6 | 1.568E-15 | 0 | 13380 | gtex_brain_ba24 |
| rs2268684 | 6 | 42677753 | PRPH2 | ENSG00000112619.6 | 2.022E-7 | 0 | 12559 | gtex_brain_ba24 |
| rs6931385 | 6 | 42677834 | PRPH2 | ENSG00000112619.6 | 3.671E-8 | 0 | 12478 | gtex_brain_ba24 |
| rs6915637 | 6 | 42677875 | PRPH2 | ENSG00000112619.6 | 2.659E-13 | 0 | 12437 | gtex_brain_ba24 |
| rs2268683 | 6 | 42678055 | PRPH2 | ENSG00000112619.6 | 1.884E-8 | 0 | 12257 | gtex_brain_ba24 |
| rs2268682 | 6 | 42678349 | PRPH2 | ENSG00000112619.6 | 1.508E-12 | 0 | 11963 | gtex_brain_ba24 |
| rs3793007 | 6 | 42681495 | PRPH2 | ENSG00000112619.6 | 1.473E-7 | 0 | 8817 | gtex_brain_ba24 |
| rs7769412 | 6 | 42682902 | PRPH2 | ENSG00000112619.6 | 5.135E-8 | 0 | 7410 | gtex_brain_ba24 |
| rs147201691 | 6 | 42684657 | PRPH2 | ENSG00000112619.6 | 3.842E-6 | 0 | 5655 | gtex_brain_ba24 |
| rs6928781 | 6 | 42689411 | PRPH2 | ENSG00000112619.6 | 3.504E-8 | 0 | 901 | gtex_brain_ba24 |
| rs11754813 | 6 | 42690514 | PRPH2 | ENSG00000112619.6 | 1.358E-7 | 0 | -202 | gtex_brain_ba24 |
| rs9296387 | 6 | 42502314 | PRPH2 | ENSG00000112619.6 | 2.68E-6 | 0 | 187998 | gtex_brain_putamen_basal |
| rs9381188 | 6 | 42505116 | PRPH2 | ENSG00000112619.6 | 2.68E-6 | 0 | 185196 | gtex_brain_putamen_basal |
| rs9369369 | 6 | 42513435 | PRPH2 | ENSG00000112619.6 | 2.175E-6 | 0 | 176877 | gtex_brain_putamen_basal |
| rs9381192 | 6 | 42518706 | PRPH2 | ENSG00000112619.6 | 5.861E-7 | 0 | 171606 | gtex_brain_putamen_basal |
| rs201247280 | 6 | 42521088 | PRPH2 | ENSG00000112619.6 | 2.568E-6 | 0 | 169224 | gtex_brain_putamen_basal |
| rs6458294 | 6 | 42522412 | PRPH2 | ENSG00000112619.6 | 9.155E-7 | 0 | 167900 | gtex_brain_putamen_basal |
| rs4499930 | 6 | 42527706 | PRPH2 | ENSG00000112619.6 | 2.814E-7 | 0 | 162606 | gtex_brain_putamen_basal |
| rs6900726 | 6 | 42531650 | PRPH2 | ENSG00000112619.6 | 3.389E-7 | 0 | 158662 | gtex_brain_putamen_basal |
| rs2181331 | 6 | 42534391 | PRPH2 | ENSG00000112619.6 | 5.076E-7 | 0 | 155921 | gtex_brain_putamen_basal |
| rs57290849 | 6 | 42540230 | PRPH2 | ENSG00000112619.6 | 2.136E-7 | 0 | 150082 | gtex_brain_putamen_basal |
| rs6920844 | 6 | 42545638 | PRPH2 | ENSG00000112619.6 | 4.661E-7 | 0 | 144674 | gtex_brain_putamen_basal |
| rs9462810 | 6 | 42546840 | PRPH2 | ENSG00000112619.6 | 2.661E-6 | 0 | 143472 | gtex_brain_putamen_basal |
| rs6458297 | 6 | 42547891 | PRPH2 | ENSG00000112619.6 | 3.343E-7 | 0 | 142421 | gtex_brain_putamen_basal |
| rs2181332 | 6 | 42551232 | PRPH2 | ENSG00000112619.6 | 2.661E-6 | 0 | 139080 | gtex_brain_putamen_basal |
| rs9394910 | 6 | 42555254 | PRPH2 | ENSG00000112619.6 | 3.345E-7 | 0 | 135058 | gtex_brain_putamen_basal |
| rs9394911 | 6 | 42562996 | PRPH2 | ENSG00000112619.6 | 6.115E-7 | 0 | 127316 | gtex_brain_putamen_basal |
| rs6902425 | 6 | 42563346 | PRPH2 | ENSG00000112619.6 | 5.144E-7 | 0 | 126966 | gtex_brain_putamen_basal |
| rs6941663 | 6 | 42566728 | PRPH2 | ENSG00000112619.6 | 4.417E-7 | 0 | 123584 | gtex_brain_putamen_basal |
| rs11751424 | 6 | 42567119 | PRPH2 | ENSG00000112619.6 | 2.549E-6 | 0 | 123193 | gtex_brain_putamen_basal |
| rs71965530 | 6 | 42567356 | PRPH2 | ENSG00000112619.6 | 4.054E-6 | 0 | 122956 | gtex_brain_putamen_basal |
| rs2025249 | 6 | 42568248 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 122064 | gtex_brain_putamen_basal |
| rs10498753 | 6 | 42571807 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 118505 | gtex_brain_putamen_basal |
| rs2025250 | 6 | 42572494 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 117818 | gtex_brain_putamen_basal |
| rs7745976 | 6 | 42573285 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 117027 | gtex_brain_putamen_basal |
| rs60649017 | 6 | 42575390 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 114922 | gtex_brain_putamen_basal |
| rs9369372 | 6 | 42575703 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 114609 | gtex_brain_putamen_basal |
| rs9369373 | 6 | 42575723 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 114589 | gtex_brain_putamen_basal |
| rs4472340 | 6 | 42580755 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 109557 | gtex_brain_putamen_basal |
| rs9462812 | 6 | 42581696 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 108616 | gtex_brain_putamen_basal |
| rs10807281 | 6 | 42582541 | PRPH2 | ENSG00000112619.6 | 3.526E-7 | 0 | 107771 | gtex_brain_putamen_basal |
| rs35018263 | 6 | 42582553 | PRPH2 | ENSG00000112619.6 | 3.528E-7 | 0 | 107759 | gtex_brain_putamen_basal |
| rs9381203 | 6 | 42583625 | PRPH2 | ENSG00000112619.6 | 3.49E-7 | 0 | 106687 | gtex_brain_putamen_basal |
| rs9296394 | 6 | 42587818 | PRPH2 | ENSG00000112619.6 | 3.49E-7 | 0 | 102494 | gtex_brain_putamen_basal |
| rs144089110 | 6 | 42588216 | PRPH2 | ENSG00000112619.6 | 9.222E-7 | 0 | 102096 | gtex_brain_putamen_basal |
| rs12153987 | 6 | 42589913 | PRPH2 | ENSG00000112619.6 | 3.146E-7 | 0 | 100399 | gtex_brain_putamen_basal |
| rs9357400 | 6 | 42591128 | PRPH2 | ENSG00000112619.6 | 3.146E-7 | 0 | 99184 | gtex_brain_putamen_basal |
| rs9349236 | 6 | 42591275 | PRPH2 | ENSG00000112619.6 | 5.363E-7 | 0 | 99037 | gtex_brain_putamen_basal |
| rs9367157 | 6 | 42591285 | PRPH2 | ENSG00000112619.6 | 5.363E-7 | 0 | 99027 | gtex_brain_putamen_basal |
| rs70990113 | 6 | 42591881 | PRPH2 | ENSG00000112619.6 | 5.309E-7 | 0 | 98431 | gtex_brain_putamen_basal |
| rs7743466 | 6 | 42592012 | PRPH2 | ENSG00000112619.6 | 2.056E-6 | 0 | 98300 | gtex_brain_putamen_basal |
| rs199997560 | 6 | 42594066 | PRPH2 | ENSG00000112619.6 | 2.043E-6 | 0 | 96246 | gtex_brain_putamen_basal |
| rs36072475 | 6 | 42594068 | PRPH2 | ENSG00000112619.6 | 2.043E-6 | 0 | 96244 | gtex_brain_putamen_basal |
| rs12529803 | 6 | 42595047 | PRPH2 | ENSG00000112619.6 | 3.412E-7 | 0 | 95265 | gtex_brain_putamen_basal |
| rs7773898 | 6 | 42599673 | PRPH2 | ENSG00000112619.6 | 3.885E-7 | 0 | 90639 | gtex_brain_putamen_basal |
| rs7753593 | 6 | 42599704 | PRPH2 | ENSG00000112619.6 | 3.675E-7 | 0 | 90608 | gtex_brain_putamen_basal |
| rs4521584 | 6 | 42608187 | PRPH2 | ENSG00000112619.6 | 3.373E-7 | 0 | 82125 | gtex_brain_putamen_basal |
| rs13213476 | 6 | 42608668 | PRPH2 | ENSG00000112619.6 | 3.345E-7 | 0 | 81644 | gtex_brain_putamen_basal |
| rs13200782 | 6 | 42614780 | PRPH2 | ENSG00000112619.6 | 2.902E-7 | 0 | 75532 | gtex_brain_putamen_basal |
| rs9471891 | 6 | 42616933 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 73379 | gtex_brain_putamen_basal |
| rs3763234 | 6 | 42617961 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 72351 | gtex_brain_putamen_basal |
| rs9367160 | 6 | 42618490 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 71822 | gtex_brain_putamen_basal |
| rs9462815 | 6 | 42618739 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 71573 | gtex_brain_putamen_basal |
| rs10807282 | 6 | 42622455 | PRPH2 | ENSG00000112619.6 | 9.663E-7 | 0 | 67857 | gtex_brain_putamen_basal |
| rs59876630 | 6 | 42626147 | PRPH2 | ENSG00000112619.6 | 3.305E-7 | 0 | 64165 | gtex_brain_putamen_basal |
| rs3736745 | 6 | 42630107 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 60205 | gtex_brain_putamen_basal |
| rs11392975 | 6 | 42630793 | PRPH2 | ENSG00000112619.6 | 9.343E-8 | 0 | 59519 | gtex_brain_putamen_basal |
| rs9394913 | 6 | 42632246 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 58066 | gtex_brain_putamen_basal |
| rs6905797 | 6 | 42642923 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 47389 | gtex_brain_putamen_basal |
| rs9367161 | 6 | 42653359 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 36953 | gtex_brain_putamen_basal |
| rs13194067 | 6 | 42655088 | PRPH2 | ENSG00000112619.6 | 3.385E-7 | 0 | 35224 | gtex_brain_putamen_basal |
| rs13193863 | 6 | 42655094 | PRPH2 | ENSG00000112619.6 | 3.901E-7 | 0 | 35218 | gtex_brain_putamen_basal |
| rs9394917 | 6 | 42660017 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 30295 | gtex_brain_putamen_basal |
| rs34394180 | 6 | 42660885 | PRPH2 | ENSG00000112619.6 | 3.297E-7 | 0 | 29427 | gtex_brain_putamen_basal |
| rs9349238 | 6 | 42663548 | PRPH2 | ENSG00000112619.6 | 2.605E-7 | 0 | 26764 | gtex_brain_putamen_basal |
| rs835 | 6 | 42665888 | PRPH2 | ENSG00000112619.6 | 3.321E-7 | 0 | 24424 | gtex_brain_putamen_basal |
| rs9471896 | 6 | 42667047 | PRPH2 | ENSG00000112619.6 | 1.004E-6 | 0 | 23265 | gtex_brain_putamen_basal |
| rs2268687 | 6 | 42668932 | PRPH2 | ENSG00000112619.6 | 9.699E-7 | 0 | 21380 | gtex_brain_putamen_basal |
| rs2268686 | 6 | 42669108 | PRPH2 | ENSG00000112619.6 | 9.82E-7 | 0 | 21204 | gtex_brain_putamen_basal |
| rs9381211 | 6 | 42670374 | PRPH2 | ENSG00000112619.6 | 2.849E-6 | 0 | 19938 | gtex_brain_putamen_basal |
| rs9394918 | 6 | 42670450 | PRPH2 | ENSG00000112619.6 | 1.247E-6 | 0 | 19862 | gtex_brain_putamen_basal |
| rs12333241 | 6 | 42671439 | PRPH2 | ENSG00000112619.6 | 1.321E-6 | 0 | 18873 | gtex_brain_putamen_basal |
| rs71765744 | 6 | 42671817 | PRPH2 | ENSG00000112619.6 | 2.987E-6 | 0 | 18495 | gtex_brain_putamen_basal |
| rs200767461 | 6 | 42671860 | PRPH2 | ENSG00000112619.6 | 8.504E-7 | 0 | 18452 | gtex_brain_putamen_basal |
| rs67162942 | 6 | 42671861 | PRPH2 | ENSG00000112619.6 | 1.093E-6 | 0 | 18451 | gtex_brain_putamen_basal |
| rs3818087 | 6 | 42672407 | PRPH2 | ENSG00000112619.6 | 2.82E-7 | 0 | 17905 | gtex_brain_putamen_basal |
| rs34722725 | 6 | 42672434 | PRPH2 | ENSG00000112619.6 | 8.322E-7 | 0 | 17878 | gtex_brain_putamen_basal |
| rs13214506 | 6 | 42672574 | PRPH2 | ENSG00000112619.6 | 8.312E-7 | 0 | 17738 | gtex_brain_putamen_basal |
| rs12333110 | 6 | 42673107 | PRPH2 | ENSG00000112619.6 | 6.255E-7 | 0 | 17205 | gtex_brain_putamen_basal |
| rs67473485 | 6 | 42674631 | PRPH2 | ENSG00000112619.6 | 8.156E-7 | 0 | 15681 | gtex_brain_putamen_basal |
| rs9367162 | 6 | 42676827 | PRPH2 | ENSG00000112619.6 | 6.209E-7 | 0 | 13485 | gtex_brain_putamen_basal |
| rs9357403 | 6 | 42676932 | PRPH2 | ENSG00000112619.6 | 1.857E-6 | 0 | 13380 | gtex_brain_putamen_basal |
| rs6915637 | 6 | 42677875 | PRPH2 | ENSG00000112619.6 | 1.051E-6 | 0 | 12437 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| ATP9B | 0.75 | 0.81 |
| TRMT2B | 0.74 | 0.76 |
| WHAMM | 0.72 | 0.74 |
| WDR42A | 0.72 | 0.76 |
| ABAT | 0.72 | 0.75 |
| PPARD | 0.72 | 0.77 |
| STAT5B | 0.72 | 0.72 |
| NSUN4 | 0.71 | 0.69 |
| FAM82A2 | 0.70 | 0.73 |
| CASP9 | 0.70 | 0.73 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.21 | -0.48 | -0.30 |
| IL32 | -0.40 | -0.30 |
| AF347015.18 | -0.40 | -0.22 |
| MT-CO2 | -0.40 | -0.25 |
| AF347015.31 | -0.39 | -0.26 |
| AF347015.8 | -0.38 | -0.23 |
| AL139819.3 | -0.38 | -0.35 |
| FAM159B | -0.38 | -0.45 |
| MT-CYB | -0.37 | -0.23 |
| AF347015.2 | -0.37 | -0.18 |
Section III. Gene Ontology annotation
| Molecular function | 去term | Evidence | Neuro keywords | PubMed ID |
|---|---|---|---|---|
| GO:0005515 | protein binding | IEA | - | |
| Biological process | 去term | Evidence | Neuro keywords | PubMed ID |
| GO:0007155 | cell adhesion | IEA | - | |
| GO:0007601 | visual perception | TAS | 1749427 | |
| GO:0050896 | response to stimulus | IEA | - | |
| Cellular component | 去term | Evidence | Neuro keywords | PubMed ID |
| GO:0016020 | membrane | IEA | - | |
| GO:0016021 | integral to membrane | TAS | 1749427 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| KEGG AMYOTROPHIC LATERAL SCLEROSIS ALS | 53 | 43 | All SZGR 2.0 genes in this pathway |
| CAIRO LIVER DEVELOPMENT UP | 166 | 105 | All SZGR 2.0 genes in this pathway |
| BROWNE HCMV INFECTION 1HR DN | 222 | 147 | All SZGR 2.0 genes in this pathway |
| PURBEY CTBP1没有SATB1的目标 | 344 | 215 | All SZGR 2.0 genes in this pathway |
| KINNEY DNMT1 METHYLATION TARGETS | 14 | 6 | All SZGR 2.0 genes in this pathway |