SZGR2 - Beplay体育中心

Summary？

GeneID	598
Symbol	BCL2L1
Synonyms	BCL-XL/S\|BCL2L\|BCLX\|Bcl-X\|PPP1R52
Description	Bcl2像1
Reference	MIM：600039\|HGNC:HGNC:992\|Ensembl:ENSG00000171552\|HPRD:02497\|Vega:OTTHUMG00000032192
基因类型	蛋白质编码
Map location	20q11.21
Pascal p-value	0.81
Sherlock p-value	0.98
胎儿β	-0.307

Gene in Data Sources

基因集名称	Method of gene set	Description	信息
PMID：cooccur	High-throughput literature-search	PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature	High-throughput literature-search	与精神分裂症关键词共同存在：精神分裂症，精神分裂症，精神分裂症	点击显示详细信息
GO_Annotation	将与神经相关的关键字映射到基因本体论注释	Hits with neuro-related keywords: 1
Network	Shortest path distance of core genes in the Human protein-protein interaction network	Contribution to shortest path in PPI network: 0.0455

Section I. Genetics and epigenetics annotation

第二节。转录组注释

一般基因表达（GTEX）

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions

第三节。基因本体论注释

Molecular function	去学期	证据	神经关键字	PubMed ID
GO：0042802	identical protein binding	IPI		15131699
Biological process	去学期	证据	神经关键字	PubMed ID
GO：0043524	negative regulation of neuron apoptosis	IEA	神经元（GO期限：9）	-
GO:0001836	release of cytochrome c from mitochondria	IDA		9843949
去：0008634	生存基因产物表达的负调节	TAS		8358789
GO:0009314	response to radiation	IEA		-
GO:0042981	regulation of apoptosis	IEA		-
GO:0045768	positive regulation of anti-apoptosis	IEA		-
GO：0046902	regulation of mitochondrial membrane permeability	IDA		9843949
GO：0051881	regulation of mitochondrial membrane potential	IDA		9843949
Cellular component	去学期	证据	神经关键字	PubMed ID
去：0005634	nucleus	IEA		-
去：0005739	线粒体	IDA		12011449
去：0005739	线粒体	IEA		-
去：0005741	mitochondrial outer membrane	EXP		9727492\|10195903\|10198631 \|11463392
去：0005741	mitochondrial outer membrane	nas		12667443
GO:0016020	membrane	IEA		-
GO:0016021	膜不可或缺	IEA		-
GO:0031965	核膜	IEA		-

Section IV. Protein-protein interaction annotation

Interactors	别名b	官方全名b	实验	Source	PubMed ID
ANTXR1	ATR \| FLJ10601 \| FLJ11298 \| FLJ21776 \| TEM8	anthrax toxin receptor 1	-	HPRD	11574549
APAF1	CED4 \| DKFZp781B1145	apoptotic peptidase activating factor 1	-	HPRD,BioGRID	9488720\|9539746
AVEN	PDCD12	apoptosis, caspase activation inhibitor	-	HPRD,BioGRID	10949025
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	-	HPRD	7834748\|9305851 \|9388232\|11483855 \|11494146\|11583631
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	Bcl-XL interacts with Bad. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bad.	绑定	15721256
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	亲和力捕获 - 韦斯特恩蛋白质肽重构的复合物 Two-hybrid	Biogrid	7834748\|9824152 \|10620799\|11206074 \|11494146\|12115603 \|12137781\|15694340 \|15705582
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	Bad interacts with Bcl-XL.	绑定	15694340
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	-	HPRD	7834748\|11494146 \| 11206074
BAD	BBC2 \| BCL2L8	BCL2相关的细胞死亡激动剂	Bad interacts with Bcl-xL.	绑定	15574335
Bag1	RAP46	BCl2相关的雅典纪	-	HPRD	10467399
BAK1	贝克\|类似bak \|bcl2l7 \|CDN1 \|MGC117255 \|MGC3887	Bcl2-Antagonist/杀手1	-	HPRD,BioGRID	11175750
BAX	BCL2L4	BCL2-associated X protein	Bax interacts with Bcl-XL via its BH3 domain. This interaction was modeled on a demonstrated interaction between mouse Bax and human Bcl-XL.	绑定	11060313
BAX	BCL2L4	BCL2-associated X protein	Bax interacts with Bcl-XL.	绑定	9372935
BAX	BCL2L4	BCL2-associated X protein	Bax interacts with Bcl-xL.	绑定	15574335
BAX	BCL2L4	BCL2-associated X protein	亲和力捕获 - 韦斯特恩蛋白质肽	Biogrid	9824152\|12137781 \|12853473
BBC3	JFY1 \| PUMA	Bcl2结合分量3	PUMA interacts with Bcl-xL.	绑定	15574335
BBC3	JFY1 \| PUMA	Bcl2结合分量3	PUMA与BCL-XL相互作用。	绑定	15694340
BBC3	JFY1 \| PUMA	Bcl2结合分量3	亲和力捕获 - 韦斯特恩	Biogrid	15694340
BBC3	JFY1 \| PUMA	Bcl2结合分量3	BCL-XL与PUMA相互作用。这种相互作用是基于未指定物种和人类PUMA的BCL-XL之间的相互作用进行建模的。	绑定	15721256
BCAP31	6C6-AG \| BAP31 \| CDM \| DXS1357E	B细胞受体相关蛋白31	-	HPRD,BioGRID	9334338
BCL2	Bcl-2	B细胞CLL/淋巴瘤2	-	HPRD	11583631
BCL2	Bcl-2	B细胞CLL/淋巴瘤2	亲和力捕获 - 韦斯特恩蛋白质肽	Biogrid	12137781\|14980220
BCL2L10	BCL-B \| Boo \| Diva \| MGC129810 \| MGC129811	BCL2-like 10 (apoptosis facilitator)	-	HPRD	11278245
BCL2L11	BAM \| BIM \| BIM-alpha6 \| BIM-beta6 \| BIM-beta7 \| BOD \| BimEL \| BimL	BCL2-like 11 (apoptosis facilitator)	-	HPRD	9430630\|10198631 \|11859372\|11859372
BCL2L11	BAM \| BIM \| BIM-alpha6 \| BIM-beta6 \| BIM-beta7 \| BOD \| BimEL \| BimL	BCL2-like 11 (apoptosis facilitator)	BIM与BCL-XL相互作用。	绑定	15694340
BCL2L11	BAM \| BIM \| BIM-alpha6 \| BIM-beta6 \| BIM-beta7 \| BOD \| BimEL \| BimL	BCL2-like 11 (apoptosis facilitator)	亲和力捕获 - 韦斯特恩 FRET	Biogrid	14596824\|15694340
BCL2L11	BAM \| BIM \| BIM-alpha6 \| BIM-beta6 \| BIM-beta7 \| BOD \| BimEL \| BimL	BCL2-like 11 (apoptosis facilitator)	-	HPRD	11859372
BCL2L11	BAM \| BIM \| BIM-alpha6 \| BIM-beta6 \| BIM-beta7 \| BOD \| BimEL \| BimL	BCL2-like 11 (apoptosis facilitator)	Bcl-XL interacts with Bim. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bim.	绑定	15721256
BCl2L14	bclg	BCL2-like 14 (apoptosis facilitator)	-	HPRD,BioGRID	11054413
BCLAF1	BTF \|KIAA0164 \|BK211L9.1	BCl2相关转录因子1	-	HPRD	10330179
BECN1	ATG6 \| VPS30 \| beclin1	beclin 1, autophagy related	-	HPRD,BioGRID	9765397
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	Bid interacts with Bcl-XL.	绑定	15694340
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	蛋白质肽	Biogrid	15694340
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	BCL-XL与BID-EL BH3死亡域的α-螺旋区相互作用。	绑定	15353804
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	BCL-XL与α螺旋的交互the BID BH3 death domain.	绑定	15353804
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	Bcl-XL interacts with Bid. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bid.	绑定	15721256
出价	FP497 \| MGC15319 \| MGC42355	BH3 interacting domain death agonist	Bid interacts with Bcl-xL.	绑定	15574335
比克	BIP1 \| BP4 \| NBK	BCL2相互作用杀手（凋亡诱导）	Bik interacts with Bcl-XL.	绑定	15694340
比克	BIP1 \| BP4 \| NBK	BCL2相互作用杀手（凋亡诱导）	-	HPRD	9525867\|11342619 \|12853473 \| 11342619\|12853473
比克	BIP1 \| BP4 \| NBK	BCL2相互作用杀手（凋亡诱导）	Bcl-XL interacts with Bik. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bik.	绑定	15721256
比克	BIP1 \| BP4 \| NBK	BCL2相互作用杀手（凋亡诱导）	-	HPRD,BioGRID	11342619\|12853473
BLK	MGC10442	B淋巴酪氨酸激酶	重构的复合物	Biogrid	9525867
BMF	FLJ00065	Bcl2 modifying factor	Bmf interacts with Bcl-XL. This interaction was modelled on a demonstrated interaction between mouse Bmf and human Bcl-XL.	绑定	15694340
BMF	FLJ00065	Bcl2 modifying factor	Bcl-XL interacts with Bmf. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bmf.	绑定	15721256
BNIP1	NIP1 \| SEC20 \| TRG-8	BCL2/adenovirus E1B 19kDa interacting protein 1	-	HPRD,BioGRID	10217402
BNIP3	NIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	-	HPRD,BioGRID	10625696
BNIP3L	BNIP3a \| NIX	Bcl2/腺病毒E1B 19KDA相互作用蛋白3类样	-	HPRD,BioGRID	9973195\|10467396\|10467396
BNIPL	BNIP-S \| BNIPL-1 \| BNIPL-2 \| BNIPL1 \| BNIPL2 \| PP753	Bcl2/腺病毒E1B 19KD相互作用的蛋白	重构的复合物 Two-hybrid	Biogrid	9973195\|12901880
CASP2	CASP-2 \|ICH-1L \|ICH-1L/1S \|ICH1 \|nedd2	caspase 2，与凋亡相关的半胱氨酸肽酶	表型抑制	Biogrid	11832478
CASP8	ALPS2B \|cap4 \|弗里斯\|FLJ17672 \|马赫\|MCH5 \|MGC78473	caspase 8, apoptosis-related cysteine peptidase	-	HPRD	11733517
CASP8	ALPS2B \|cap4 \|弗里斯\|FLJ17672 \|马赫\|MCH5 \|MGC78473	caspase 8, apoptosis-related cysteine peptidase	表型抑制	Biogrid	11832478
CASP9	APAF-3 \| APAF3 \| CASPASE-9c \| ICE-LAP6 \| MCH6	caspase 9, apoptosis-related cysteine peptidase	-	HPRD,BioGRID	9539746
CFLAR	现金\|casp8ap1 \|克拉普\|卡斯珀\|火焰\|火焰1 \|火焰1 \|翻转\|i-flice \|MRIT \| c-FLIP \| c-FLIPL \| c-FLIPR \| c-FLIPS	CASP8 and FADD-like apoptosis regulator	-	HPRD,BioGRID	9326610
CFLAR	现金\|casp8ap1 \|克拉普\|卡斯珀\|火焰\|火焰1 \|火焰1 \|翻转\|i-flice \|MRIT \| c-FLIP \| c-FLIPL \| c-FLIPR \| c-FLIPS	CASP8 and FADD-like apoptosis regulator	MRIT-alpha-1 interacts with BclXL. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and BclXL from an unspecified species.	绑定	9326610
cryaa	crya1 \|HSPB4	结晶，alpha a	Halphaa-Crystallin与BCL-XS相互作用。	绑定	14752512
Cryab	CRYA2 \| CTPP2 \| HSPB5	结晶蛋白，alpha b	Halphab-晶状蛋白与BCL-XS相互作用。	绑定	14752512
CYCS	CYC \|HCS	细胞色素C，体细胞	-	HPRD,BioGRID	9192670
dynll1	DLC1 \| DLC8 \| DNCL1 \| DNCLC1 \| LC8 \| LC8a \| MGC126137 \| MGC126138 \| PIN \| hdlc1	Dynein，轻链，LC8型1	亲和力捕获 - 韦斯特恩	Biogrid	10198631
FKBP8	FKBP38 \| FKBPr38	FK506 binding protein 8, 38kDa	-	HPRD,BioGRID	12510191
hrk	DP5 \| HARAKIRI	Harakiri，Bcl2相互作用蛋白（仅包含BH3域）	-	HPRD	9130713\|10075695
hrk	DP5 \| HARAKIRI	Harakiri，Bcl2相互作用蛋白（仅包含BH3域）	Hrk interacts with Bcl-XL.	绑定	15694340
hrk	DP5 \| HARAKIRI	Harakiri，Bcl2相互作用蛋白（仅包含BH3域）	Bcl-XL interacts with Hrk. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Hrk.	绑定	15721256
hrk	DP5 \| HARAKIRI	Harakiri，Bcl2相互作用蛋白（仅包含BH3域）	Hrk interacts with Bcl-XL.	绑定	9130713
hrk	DP5 \| HARAKIRI	Harakiri，Bcl2相互作用蛋白（仅包含BH3域）	-	HPRD,BioGRID	9130713\|10075695
IKZF3	AIO \| AIOLOS \| ZNFN1A3	ikaros家族锌指3（Aiolos）	-	HPRD,BioGRID	11714801
IRS1	HIRS-1	insulin receptor substrate 1	-	HPRD,BioGRID	10679027
IRS2	-	insulin receptor substrate 2	-	HPRD	10679027
MCL1	BCL2L3 \| EAT \| MCL1L \| MCL1S \| MGC104264 \| MGC1839 \| TM	髓样细胞白血病序列1（与BCL2相关）	亲和力捕获 - 韦斯特恩	Biogrid	10837489
MOAP1	MAP-1 \|PNMA4	modulator of apoptosis 1	MAP-1 interacts with Bcl-XL via its amino and carboxy terminal regions.	绑定	11060313
MOAP1	MAP-1 \|PNMA4	modulator of apoptosis 1	-	HPRD,BioGRID	11060313
PMAIP1	APR \| NOXA	phorbol-12-催眠13-乙酸盐诱导的蛋白质1	-	HPRD,BioGRID	10807576
PPP1CA	MGC15877 \| MGC1674 \| PP-1A \| PPP1A	蛋白质磷酸酶1，催化亚基，α同工型	-	HPRD,BioGRID	12115603
PSEN1	AD3 \| FAD \| PS1 \| S182	Presenilin 1	-	HPRD,BioGRID	10446169
PSEN2	AD3L \| AD4 \| PS2 \| STM2	Presenilin 2（阿尔茨海默氏病4）	-	HPRD,BioGRID	10446169
RAD9A	RAD9	RAD9 homolog A (S. pombe)	亲和力捕获 - 韦斯特恩 Two-hybrid	Biogrid	10620799\|16189514
RAF1	克拉夫\|NS5 \|RAF-1 \|C-Raf	v-raf-1 murine leukemia viral oncogene homolog 1	重构的复合物	Biogrid	8929532
RTN1	MGC133250 \| NSP	reticulon 1	NSP-C与BCL-XL相互作用。	绑定	11126360
RTN1	MGC133250 \| NSP	reticulon 1	-	HPRD,BioGRID	11126360
RTN4	Asy \|NI220/250 \|nogo \|nogo-a \|Nogoc \|NSP \|NSP-CL \|NBLA00271 \|NBLA10545 \|nogo-b \| Nogo-C \| RTN-X \| RTN4-A \| RTN4-B1 \| RTN4-B2 \| RTN4-C	reticulon 4	-	HPRD,BioGRID	11126360
RTN4	Asy \|NI220/250 \|nogo \|nogo-a \|Nogoc \|NSP \|NSP-CL \|NBLA00271 \|NBLA10545 \|nogo-b \| Nogo-C \| RTN-X \| RTN4-A \| RTN4-B1 \| RTN4-B2 \| RTN4-C	reticulon 4	RTN-XS interacts with Bcl-XL.	绑定	11126360
SIVA1	CD27BP \| SIVA \| Siva-1 \| Siva-2	SIVA1, apoptosis-inducing factor	-	HPRD	12011449
SNCA	MGC110988 \|NACP \|park1 \|park4 \|PD1	synuclein, alpha (non A4 component of amyloid precursor)	-	HPRD	11742726
SPNS1	FLJ38358 \| HSpin1 \| LAT \| PP2030 \| SPIN1 \| SPINL \| nrs	Spinster同源1（果蝇）	-	HPRD,BioGRID	12815463
TMBIM6	BAXI1 \| BI-1 \| TEGT	包含6个的跨膜bax抑制剂基序	-	HPRD	9660918
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	肿瘤蛋白p53	Bcl-xl interacts with p53.	绑定	14963330
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	肿瘤蛋白p53	-	HPRD	12667443
TPT1	FLJ27337 \| HRF \| TCTP \| p02	tumor protein, translationally-controlled 1	Bcl-xL interacts with TCTP.	绑定	15870695
VDAC1	MGC111064 \|波林\|Porin-31-HL	voltage-dependent anion channel 1	亲和力捕获 - 韦斯特恩重构的复合物	Biogrid	10365962\|10737788 \|12767928\|15637055
VDAC1	MGC111064 \|波林\|Porin-31-HL	voltage-dependent anion channel 1	-	HPRD	10049775\|10365962 \|10737788

Section V. Pathway annotation

路径名	路径大小	# SZGR 2.0 genes in pathway	信息
KEGG APOPTOSIS	88	62	All SZGR 2.0 genes in this pathway
KEGG JAK STAT SIGNALING PATHWAY	155	105	All SZGR 2.0 genes in this pathway
KEGG AMYOTROPHIC LATERAL SCLEROSIS ALS	53	43	All SZGR 2.0 genes in this pathway
癌症中的KEGG途径	328	259	All SZGR 2.0 genes in this pathway
KEGG PANCREATIC CANCER	70	56	All SZGR 2.0 genes in this pathway
KEGG慢性髓细胞性白血病	73	59	All SZGR 2.0 genes in this pathway
KEGG SMALL CELL LUNG CANCER	84	67	All SZGR 2.0 genes in this pathway
BIOCARTA CHEMICAL PATHWAY	22	15	All SZGR 2.0 genes in this pathway
BIOCARTA IL2RB PATHWAY	38	26	All SZGR 2.0 genes in this pathway
Biocarta RAS途径	23	20	All SZGR 2.0 genes in this pathway
Biocarta坏路	26	23	All SZGR 2.0 genes in this pathway
BIOCARTA MITOCHONDRIA PATHWAY	21	15	All SZGR 2.0 genes in this pathway
SIG PIP3在心脏肌周期中发出信号	67	54	All SZGR 2.0 genes in this pathway
SA编程的细胞死亡	12	9	All SZGR 2.0 genes in this pathway
PID IL4 2PATHWAY	65	43	All SZGR 2.0 genes in this pathway
PID CD40通路	31	26	All SZGR 2.0 genes in this pathway
PID NFAT 3PATHWAY	54	47	All SZGR 2.0 genes in this pathway
PID IL2 PI3K途径	34	27	All SZGR 2.0 genes in this pathway
PID P53 DOWNSTREAM PATHWAY	137	94	All SZGR 2.0 genes in this pathway
PID ERBB1 DOWNSTREAM PATHWAY	105	78	All SZGR 2.0 genes in this pathway
PID ATF2 PATHWAY	59	43	All SZGR 2.0 genes in this pathway
PID IL3 PATHWAY	27	19	All SZGR 2.0 genes in this pathway
PID IL6 7 PATHWAY	47	40	All SZGR 2.0 genes in this pathway
PID EPO PATHWAY	34	29	All SZGR 2.0 genes in this pathway
PID IL2 STAT5 PATHWAY	30	23	All SZGR 2.0 genes in this pathway
PID PI3KCI AKT PATHWAY	35	30	All SZGR 2.0 genes in this pathway
REACTOME APOPTOSIS	148	94	All SZGR 2.0 genes in this pathway
Reactome先天免疫系统	279	178	All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM	933	616	All SZGR 2.0 genes in this pathway
反应组炎症	17	12	All SZGR 2.0 genes in this pathway
反应组核苷酸结合结构域富含受体NLR信号通路富含亮氨酸的重复途径	46	33	All SZGR 2.0 genes in this pathway
REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	30	21	All SZGR 2.0 genes in this pathway
PUIFFE INVASION INHIBITED BY ASCITES UP	82	51	All SZGR 2.0 genes in this pathway
迪亚兹慢性巨态性白血病	1382	904	All SZGR 2.0 genes in this pathway
grabarczyk bcl11b目标dn	57	35	All SZGR 2.0 genes in this pathway
NOJIMA SFRP2 TARGETS DN	25	18	All SZGR 2.0 genes in this pathway
WANG CLIM2 TARGETS UP	269	146	All SZGR 2.0 genes in this pathway
Senese HDAC1靶向	457	269	All SZGR 2.0 genes in this pathway
SENESE HDAC1 AND HDAC2 TARGETS UP	238	144	All SZGR 2.0 genes in this pathway
SENESE HDAC3 TARGETS UP	501	327	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE FIMA UP	544	308	All SZGR 2.0 genes in this pathway
ZHOU INFLAMMATORY RESPONSE LPS UP	431	237	All SZGR 2.0 genes in this pathway
Kim WT1靶向DN	459	276	All SZGR 2.0 genes in this pathway
甲状腺癌的甲状腺癌间变性	722	443	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE EPIDERMIS UP	293	179	All SZGR 2.0 genes in this pathway
LAU APOPTOSIS CDKN2A UP	55	40	All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 UP	329	196	All SZGR 2.0 genes in this pathway
BEGUM TARGETS OF PAX3 FOXO1 FUSION DN	45	34	All SZGR 2.0 genes in this pathway
RAMJAUN APOPTOSIS BY TGFB1 VIA SMAD4 DN	8	6	All SZGR 2.0 genes in this pathway
MARKS HDAC TARGETS DN	15	11	All SZGR 2.0 genes in this pathway
GALLUZZI PERMEABILIZE MITOCHONDRIA	43	31	All SZGR 2.0 genes in this pathway
dutta凋亡通过NFKB	33	25	All SZGR 2.0 genes in this pathway
加鲁兹防止线粒体通透性	22	16	All SZGR 2.0 genes in this pathway
SHANK TAL1 TARGETS DN	10	6	All SZGR 2.0 genes in this pathway
Buytaert光动力疗法应力DN	637	377	All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS DN	261	155	All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN	514	330	All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP	487	286	All SZGR 2.0 genes in this pathway
Schaeffer Sox9在前列腺开发中的目标	21	19	All SZGR 2.0 genes in this pathway
AMIT EGF RESPONSE 480 HELA	164	118	All SZGR 2.0 genes in this pathway
AMIT SERUM RESPONSE 240 MCF10A	57	36	All SZGR 2.0 genes in this pathway
PENG LEUCINE DEPRIVATION DN	187	122	All SZGR 2.0 genes in this pathway
Mootha Voxphos	87	51	All SZGR 2.0 genes in this pathway
NEMETH INFLAMMATORY RESPONSE LPS UP	88	64	All SZGR 2.0 genes in this pathway
KANG IMMORTALIZED BY TERT UP	89	61	All SZGR 2.0 genes in this pathway
AFFAR YY1 TARGETS UP	214	133	All SZGR 2.0 genes in this pathway
WU HBX TARGETS 1 DN	23	14	All SZGR 2.0 genes in this pathway
MARIADASON REGULATED BY HISTONE ACETYLATION UP	83	49	All SZGR 2.0 genes in this pathway
WEIGEL OXIDATIVE STRESS BY HNE AND TBH	60	42	All SZGR 2.0 genes in this pathway
VARELA ZMPSTE24 TARGETS UP	40	30	All SZGR 2.0 genes in this pathway
WU HBX目标2向上	23	13	All SZGR 2.0 genes in this pathway
马丁内斯对trabectedin dn的反应	271	175	All SZGR 2.0 genes in this pathway
Sansom APC MYC目标	217	138	All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS DN	292	189	All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS SILENCED BY METHYLATION DN	281	179	All SZGR 2.0 genes in this pathway
MARZEC IL2 SIGNALING UP	115	80	All SZGR 2.0 genes in this pathway
MATZUK精子细胞	72	55	All SZGR 2.0 genes in this pathway
BLUM RESPONSE TO SALIRASIB UP	245	159	All SZGR 2.0 genes in this pathway
冬季缺氧metagene	242	168	All SZGR 2.0 genes in this pathway
MOOTHA HUMAN MITODB 6 2002	429	260	All SZGR 2.0 genes in this pathway
MOOTHA MITOCHONDRIA	447	277	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA D CLUSTER DN	40	26	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C D UP	139	95	All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP	1305	895	All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION	368	247	All SZGR 2.0 genes in this pathway
ZHAN MULTIPLE MYELOMA CD1 DN	45	30	All SZGR 2.0 genes in this pathway
Hirsch细胞转换签名	242	159	All SZGR 2.0 genes in this pathway
QI HYPOXIA TARGETS OF HIF1A AND FOXA2	37	27	All SZGR 2.0 genes in this pathway
ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS DN	116	74	All SZGR 2.0 genes in this pathway
BHAT ESR1不是通过AKT1 DN的目标	88	61	All SZGR 2.0 genes in this pathway
BHAT ESR1通过AKT1 DN目标	82	51	All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 2 UP	140	94	All SZGR 2.0 genes in this pathway
MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP	259	159	All SZGR 2.0 genes in this pathway
Krieg缺氧不是通过KDM3A	770	480	All SZGR 2.0 genes in this pathway
Fortschegger PHF8靶向DN	784	464	All SZGR 2.0 genes in this pathway
BOSCO ALLERGEN INDUCED TH2 ASSOCIATED MODULE	151	86	All SZGR 2.0 genes in this pathway
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF	516	308	All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family	Target position			miRNA ID	mirna seq
miRNA family	UTR开始	UTR结束	匹配方法	miRNA ID	mirna seq
let-7/98	945	952	1A，M8	hsa-let-7a^brain	ugagguaguaguauauaguu
				hsa-let-7b^brain	ugagguaguagguuguguguguu
				hsa-let-7c^brain	UGAGGUAGUAGGUUGUAUGGUU
				hsa-let-7d^brain	AGAGGUAGUAGGUUGCAUAGU
				hsa-let-7e^brain	UGAGGUAGGAGGUUGUAUAGU
				hsa-let-7f^brain	UGAGGUAGUAGAUUGUAUAGUU
				hsa-miR-98^brain	UGAGGUAGUAAGUUGUAUUGUU
				hsa-let-7g^SZ	UGAGGUAGUAGUUUGUACAGU
				hsa-let-7i^brain	ugagguaguugugugugugcugu
miR-133	764	771	1A，M8	hsa-miR-133a	uugguccccuucaaccagcugu
miR-133	764	771	1A，M8	hsa-miR-133b	UUGGUCCCCUUCAACCAGCUA
miR-142-3p	88	94	1A	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
mir-326	791	797	m8	hsa-miR-326	CCUCUGGGCCCUUCCUCCAG
miR-377	1441	1448	1A，M8	HSA-MIR-377	AUCACACAAAGGCAACUUUUGU
miR-491	187	193	1A	HSA-MIR-491^brain	AGUGGGGAACCCUUCCAUGAGGA
miR-495	1233	1239	1A	HSA-MIR-495^brain	Aaacaaacauggugcacuuuuu

SZ：在精神分裂症患者的脑皮质中差异表达的miRNA与使用微阵列进行对照样品进行比较。点击hereto see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Clickhere查看与大脑相关的miRNA列表。

Gene Page:BCL2L1