Gene Page:ACSM3

Summary?
GeneID 6296
Symbol ACSM3
Synonyms SA|SAH
Description acyl-CoA synthetase medium-chain family member 3
Reference MIM:145505|HGNC:HGNC:10522|Ensembl:ENSG00000005187|HPRD:07033|Vega:OTTHUMG00000131552
Gene type protein-coding
Map location 16p13.11
Pascal p-value 0.046

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
GSMA_IIE Genome scan meta-analysis (European-ancestry samples) Psr: 0.01775

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
TRERF1 0.68 0.76
HS6ST2 0.68 0.74
FOXRED2 0.64 0.75
NRXN3 0.64 0.74
ABAT 0.64 0.71
MAGI1 0.64 0.74
TSHZ1 0.63 0.70
SH3RF1 0.63 0.74
AJAP1 0.62 0.67
PCDH1 0.61 0.68
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
C1orf54 -0.39 -0.49
MT-CO2 -0.39 -0.44
AF347015.21 -0.38 -0.45
AL139819.3 -0.37 -0.45
AF347015.31 -0.36 -0.41
NOSTRIN -0.36 -0.40
FXYD1 -0.36 -0.38
S100A13 -0.36 -0.38
HIGD1B -0.36 -0.39
CLEC2B -0.35 -0.44

Section III. Gene Ontology annotation

Molecular function 去后m Evidence Neuro keywords PubMed ID
GO:0000166 nucleotide binding IEA -
GO:0000287 magnesium ion binding IEA -
GO:0005524 ATP binding IEA -
GO:0016874 ligase activity IEA -
GO:0015645 fatty-acid ligase activity IEA -
GO:0047760 butyrate-CoA ligase activity IEA -
Biological process 去后m Evidence Neuro keywords PubMed ID
GO:0008217 regulation of blood pressure NAS 7907320
GO:0008152 metabolic process IEA -
GO:0006633 fatty acid biosynthetic process IEA -
GO:0006629 lipid metabolic process IEA -
Cellular component 去后m Evidence Neuro keywords PubMed ID
GO:0005575 cellular_component ND -
GO:0005739 mitochondrion IEA -
GO:0005759 mitochondrial matrix IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG BUTANOATE新陈代谢 34 20 All SZGR 2.0 genes in this pathway
GAZDA DIAMOND BLACKFAN ANEMIA ERYTHROID DN 493 298 All SZGR 2.0 genes in this pathway
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 DN 175 82 All SZGR 2.0 genes in this pathway
DIAZ CHRONIC MEYLOGENOUS LEUKEMIA UP 1382 904 All SZGR 2.0 genes in this pathway
DOANE RESPONSE TO ANDROGEN UP 184 125 All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS DN 384 230 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL UP 233 161 All SZGR 2.0 genes in this pathway
TAKEDA TARGETS OF NUP98 HOXA9 FUSION 3D UP 182 110 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 1 UP 276 165 All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL BREAST 6 7WK DN 79 54 All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER DN 203 134 All SZGR 2.0 genes in this pathway
LIANG HEMATOPOIESIS STEM CELL NUMBER SMALL VS HUGE DN 33 22 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487 286 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER DENA DN 74 45 All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546 351 All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP 555 346 All SZGR 2.0 genes in this pathway
ROSS AML WITH AML1 ETO FUSION 76 55 All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES 244 154 All SZGR 2.0 genes in this pathway
LI WILMS TUMOR VS FETAL KIDNEY 1 UP 182 119 All SZGR 2.0 genes in this pathway
RIZKI TUMOR INVASIVENESS 3D DN 270 181 All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS 425 261 All SZGR 2.0 genes in this pathway
WEST ADRENOCORTICAL TUMOR UP 294 199 All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS CTNNB1 UP 176 110 All SZGR 2.0 genes in this pathway
HOSHIDA LIVER CANCER SURVIVAL DN 113 76 All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION 368 247 All SZGR 2.0 genes in this pathway
ACOSTA PROLIFERATION INDEPENDENT MYC TARGETS DN 116 74 All SZGR 2.0 genes in this pathway
ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY 1725 838 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-140 58 65 1A,m8 hsa-miR-140brain AGUGGUUUUACCCUAUGGUAG