Gene Page:SALL2

Summary?
GeneID 6297
Symbol SALL2
Synonyms COLB|HSAL2|Sal-2|ZNF795|p150(Sal2)
Description spalt-like transcription factor 2
Reference MIM:602219|HGNC:HGNC:10526|Ensembl:ENSG00000165821|HPRD:03743|Vega:OTTHUMG00000168826
Gene type protein-coding
Map location 14q11.1-q12
Pascal p-value 0.632
DEG p-value DEG:Sanders_2014:DS1_p=0.149:DS1_beta=0.038200:DS2_p=2.94e-03:DS2_beta=0.151:DS2_FDR=3.34e-02
Fetal beta 0.673
eGene 元
Support CompositeSet
Darnell FMRP targets

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DEG:Sanders_2013 Microarray Whole-genome gene expression profiles using microarrays on lymphoblastoid cell lines (LCLs) from 413 cases and 446 controls.
GSMA_I Genome scan meta-analysis Psr: 0.047

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception我们eks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
NTNG1 0.79 0.80
KCNK13 0.79 0.74
SLC17A6 0.79 0.66
TTC39A 0.79 0.66
PTPN3 0.79 0.67
BTBD11 0.78 0.75
PAPPA 0.77 0.41
CIT 0.76 0.74
B3GALTL 0.76 0.72
RGS16 0.76 0.41
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
PLEKHO1 -0.28 -0.29
SIGIRR -0.28 -0.48
WDR86 -0.26 -0.29
IGFBP2 -0.25 -0.30
RPL28 -0.25 -0.44
NEUROD2 -0.25 -0.15
FOXG1B -0.24 -0.14
ISLR2 -0.24 -0.07
SH2D2A -0.24 -0.41
EIF4EBP1 -0.24 -0.34

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0003700 transcription factor activity NAS -
GO:0008270 zinc ion binding IEA -
GO:0046872 metal ion binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006355 regulation of transcription, DNA-dependent NAS -
GO:0006350 transcription IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0005622 intracellular IEA -
GO:0005634 nucleus NAS -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
GAL LEUKEMIC STEM CELL UP 133 78 All SZGR 2.0 genes in this pathway
DELYS THYROID CANCER DN 232 154 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 1 UP 121 71 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 DN 229 142 All SZGR 2.0 genes in this pathway
OUELLET CULTURED OVARIAN CANCER INVASIVE VS LMP UP 69 40 All SZGR 2.0 genes in this pathway
RICKMAN METASTASIS UP 344 180 All SZGR 2.0 genes in this pathway
BENPORATH ES 1 379 235 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
LI WILMS TUMOR VS FETAL KIDNEY 1 DN 163 115 All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE UP 244 165 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 UP 428 266 All SZGR 2.0 genes in this pathway
LABBE WNT3A TARGETS UP 112 71 All SZGR 2.0 genes in this pathway
CONRAD STEM CELL 39 27 All SZGR 2.0 genes in this pathway
LI WILMS TUMOR 27 12 All SZGR 2.0 genes in this pathway
CHIANG LIVER CANCER SUBCLASS PROLIFERATION UP 178 108 All SZGR 2.0 genes in this pathway
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP 682 440 All SZGR 2.0 genes in this pathway
WIERENGA STAT5A TARGETS DN 213 127 All SZGR 2.0 genes in this pathway
DELACROIX RAR BOUND ES 462 273 All SZGR 2.0 genes in this pathway