SZGR2 - Beplay体育中心

Summary?

基因	6303
Symbol	SAT1
同义词	DC21\|KFSD\|KFSDX\|SAT\|SSAT\|SSAT-1
描述	spermidine/spermine N1-acetyltransferase 1
参考	MIM:313020\|HGNC：HGNC：10540\|ENSEMBL：ENSG00000130066\|HPRD:02431\|Vega：Otthumg0000000021256
Gene type	protein-coding
地图位置	XP22.1
Sherlock P值	0.441
Fetal beta	-0.244
支持	Potential synaptic genes

Gene in Data Sources

Gene set name	基因组方法	描述	Info
简历：PGCNP	全基因组协会研究	GWAS
PMID:cooccur	高通量文献搜索	系统的搜索in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
文学	高通量文献搜索	与精神分裂症关键词共同存在：精神分裂症，精神分裂症	Click to show details

部分即遗传学和表观遗传学注释

Section II. Transcriptome annotation

General gene expression (GTEx)

Devlopment期间的基因表达（BrainCloud）

Footnote:
总共绘制了269个时间点，n = 38个胎儿样品（x = 1：38）。每个三角形代表一个时间点。

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
The bar shown representes the lower 25% and upper 25% of the expression distribution.

大脑区域没有共表达基因

第四节。蛋白质蛋白相互作用注释

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
ABCB8	EST328128 \|M-ABC1 \|MABC1	ATP-binding cassette, sub-family B (MDR/TAP), member 8	Two-hybrid	BioGRID	16169070
APLP1	APLP	amyloid beta (A4) precursor-like protein 1	Two-hybrid	BioGRID	16169070
B4GALT3	beta4Gal-T3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3	Two-hybrid	BioGRID	16169070
C14orf1	ERG28 \|Net51	chromosome 14 open reading frame 1	Two-hybrid	BioGRID	16169070
C1orf103	FLJ11269 \|RIF1 \|RP11-96K19.1	chromosome 1 open reading frame 103	Two-hybrid	BioGRID	16169070
C7orf64	DKFZP564O0523 \| DKFZp686D1651 \| HSPC304	染色体7开放阅读框64	Two-hybrid	BioGRID	16169070
C9orf46	AD025 \|FLJ14688 \|FLJ39176 \|MDS030	chromosome 9 open reading frame 46	Two-hybrid	BioGRID	16169070
CCDC44	-	包含44	Two-hybrid	BioGRID	16189514
CCDC90B	MDS011 \| MDS025 \| MGC104239	coiled-coil domain containing 90B	Two-hybrid	BioGRID	16169070
CHD3	Mi-2a \|mi2-alpha \|ZFH	染色体群酶DNA结合蛋白3	Two-hybrid	BioGRID	16169070
COPS6	CSN6 \| MOV34-34KD	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	Two-hybrid	BioGRID	16169070
CRMP1	DPYSL1 \| DRP-1 \| DRP1	折叠蛋白反应介质蛋白1	Two-hybrid	BioGRID	16169070
DGKZ	DAGK5 \| DAGK6 \| DGK-ZETA \| hDGKzeta	diacylglycerol kinase, zeta 104kDa	Two-hybrid	BioGRID	16169070
DNPEP	Aspep \|DAP	aspartyl aminopeptidase	Two-hybrid	BioGRID	16189514
EEF1G	EF1G \|GIG35	eukaryotic translation elongation factor 1 gamma	Two-hybrid	BioGRID	16169070
EPHB6	hep \|MGC129910 \|MGC129911	EPH受体B6	Two-hybrid	BioGRID	16169070
FAM176A	FLJ13391 \| TMEM166	具有序列相似性的家庭176，成员a	Two-hybrid	BioGRID	16169070
FAM86C	FLJ10661 \|FLJ27199 \|MGC45068	family with sequence similarity 86, member C	Two-hybrid	BioGRID	16189514
FTSJ3	EPCS3 \| FLJ20062	FTSJ同源物3（大肠杆菌）	Two-hybrid	BioGRID	16189514
FUNDC2	DC44 \|FLJ33773 \|HCBP6 \|HCC3 \|MGC131676 \|MGC2495 \|PD03104	FUN14 domain containing 2	Two-hybrid	BioGRID	16169070
GBP2	-	鸟烯基结合蛋白2，干扰素诱导	Two-hybrid	BioGRID	16169070
GDF9	-	生长分化因子9	Two-hybrid	BioGRID	16169070
HOXB6	HOX2 \|HOX2B \|Hu-2 \|HOX-2.2	homeobox B6	Two-hybrid	BioGRID	16189514
HOXB9	HOX-2.5 \|HOX2 \|Hox2e	homeobox B9	Two-hybrid	BioGRID	16189514
HSPE1	CPN10 \| GROES \| HSP10	热冲击10KDA蛋白1（伴侣蛋白10）	Two-hybrid	BioGRID	16169070
INO80C	C18orf37 \| FLJ38183 \| IES6 \| hIes6	INO80复合体亚基C	Two-hybrid	BioGRID	16169070
itgb1bp3	MGC126624 \| MIBP \| NRK2	整合素β1结合蛋白3	Two-hybrid	BioGRID	16169070
Kat5	esa1 \|htatip \|htatip1 \|plip \|提示\|TIP60 \|CPLA2	K(lysine) acetyltransferase 5	Two-hybrid	BioGRID	16169070
KCNA4	HBK4 \|HK1 \|HPCN2 \|Hukii \|kcna4l \|kcna8 \|KV1.4 \|PCN2	钾电压门控通道，与振动振动器相关的亚科，成员4	Two-hybrid	BioGRID	16169070
KIAA1377	-	KIAA1377	Two-hybrid	BioGRID	16169070
LNX1	LNX \| MPDZ \| PDZRN2	Numb蛋白X 1的配体	Two-hybrid	BioGRID	16189514
luc7l2	CGI-59 \| CGI-74 \| FLJ10657 \| LUC7B2	Luc7样2（S. cerevisiae）	Two-hybrid	BioGRID	16169070
MED31	3110004H13rik \|CGI-125 \|FLJ27436 \|FLJ36714 \|SOH1	中介复合体亚基31	Two-hybrid	BioGRID	16169070
MYST2	HBO1 \|HBOA \|Kat7	MYST histone acetyltransferase 2	Two-hybrid	BioGRID	16169070
PTN	竖琴\|HBGF8 \|hbnf \|negf1	pleiotrophin	Two-hybrid	BioGRID	16169070
RBM17	MGC14439 \|SPF45	RNA binding motif protein 17	Two-hybrid	BioGRID	16189514
RPLP1	FLJ27448 \|MGC5215 \|P1 \|RPP1	核糖体蛋白，大，P1	Two-hybrid	BioGRID	16169070
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	Two-hybrid	BioGRID	16189514
SAT1	DC21 \| KFSD \| SAT \| SSAT \| SSAT-1	spermidine/spermine N1-acetyltransferase 1	-	HPRD	8670140
SAT2	SSAT2	精子/精子N1-乙酰转移酶家族成员2	Two-hybrid	BioGRID	16189514
SEPHS1	MGC4980 \|SELD \|SPS \|SPS1	硒磷酸合成酶1	Two-hybrid	BioGRID	16169070
setDB1	ESET \| KG1T \| KIAA0067 \| KMT1E	SET domain, bifurcated 1	Two-hybrid	BioGRID	16169070
TCF25	FKSG26 \|Hulp1 \|KIAA1049 \|nulp1 \|Pro2620 \|HKIAA1049	transcription factor 25 (basic helix-loop-helix)	Two-hybrid	BioGRID	16189514
TLE1	ESG \| ESG1 \| GRG1	分裂1（E（SP1）同源物，果蝇）的透明蛋白样增强剂	Two-hybrid	BioGRID	16169070
TMEM66	FLJ22274 \| FOAP-7 \| HSPC035 \| MGC8721 \| XTP3	跨膜蛋白66	Two-hybrid	BioGRID	16169070
TP53	FLJ92943 \| LFS1 \| TRP53 \| p53	tumor protein p53	Two-hybrid	BioGRID	16169070
TSC22D4	THG-1 \| THG1	TSC22域家庭，成员4	Two-hybrid	BioGRID	16189514
TUBB2A	TUBB \| TUBB2 \| dJ40E16.7	tubulin, beta 2A	Two-hybrid	BioGRID	16169070
UNC119	HRG4	UNC-119同源物（秀丽隐杆线虫）	Two-hybrid	BioGRID	16169070
UTP14A	KIAA0266 \| NY-CO-16 \| SDCCAG16 \| dJ537K23.3	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	Two-hybrid	BioGRID	16169070
ZHX1	-	锌的手指和同源蛋白酶1	Two-hybrid	BioGRID	16169070

V.途径注释

Pathway name	Pathway size	＃szgr 2.0基因	Info
Kegg精氨酸和脯氨酸代谢	54	39	All SZGR 2.0 genes in this pathway
PID整合素A9B1途径	25	18	All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	200	136	All SZGR 2.0 genes in this pathway
REACTOME METABOLISM OF POLYAMINES	15	11	All SZGR 2.0 genes in this pathway
KIM对TSA和Decitabine的反应	129	73	All SZGR 2.0 genes in this pathway
FULCHER INFLAMMATORY RESPONSE LECTIN VS LPS DN	463	290	All SZGR 2.0 genes in this pathway
GARY CD5 TARGETS UP	473	314	All SZGR 2.0 genes in this pathway
PUIFFE INVASION INHIBITED BY ASCITES DN	145	91	All SZGR 2.0 genes in this pathway
刘cmyb靶向	165	106	All SZGR 2.0 genes in this pathway
BORCZUK MALIGNANT MESOTHELIOMA DN	104	59	All SZGR 2.0 genes in this pathway
Basaki YBX1靶向DN	384	230	All SZGR 2.0 genes in this pathway
Bilban B Cll LPL DN	42	25	All SZGR 2.0 genes in this pathway
AKL HTLV1感染	27	16	All SZGR 2.0 genes in this pathway
PAPASPYRIDONOS UNSTABLE ATEROSCLEROTIC PLAQUE UP	52	36	All SZGR 2.0 genes in this pathway
UDayakumar Med1靶向DN	240	171	All SZGR 2.0 genes in this pathway
Odonnell TFRC靶向	456	228	All SZGR 2.0 genes in this pathway
MYC和TFRC的Odonnell目标	83	50	All SZGR 2.0 genes in this pathway
Senese HDAC3靶向	501	327	All SZGR 2.0 genes in this pathway
LEE NEURAL CREST STEM CELL DN	118	79	All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR DN	214	133	All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION DN	329	219	All SZGR 2.0 genes in this pathway
Scibetta KDM5B靶向	19	12	All SZGR 2.0 genes in this pathway
埃尔维奇缺氧	171	112	All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA BY DMOG UP	130	85	All SZGR 2.0 genes in this pathway
多德鼻咽癌	1821年	933	All SZGR 2.0 genes in this pathway
Gozgit ESR1靶向DN	781	465	All SZGR 2.0 genes in this pathway
PROVENZANI METASTASIS UP	194	112	All SZGR 2.0 genes in this pathway
MARKEY RB1 ACUTE LOF UP	215	137	All SZGR 2.0 genes in this pathway
环氧化物素的浓凋亡	239	157	All SZGR 2.0 genes in this pathway
甲基化调节的米西亚利亚	126	78	All SZGR 2.0 genes in this pathway
McBryan Pubertal乳房4 5WK	271	175	All SZGR 2.0 genes in this pathway
MCBRYAN PUBERTAL TGFB1 TARGETS UP	169	127	All SZGR 2.0 genes in this pathway
tomida转移DN	18	11	All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 XPC向上	28	16	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 TTD UP	64	39	All SZGR 2.0 genes in this pathway
Schlosser血清反应DN	712	443	All SZGR 2.0 genes in this pathway
XU HGF信令不通过AKT1 6小时	26	15	All SZGR 2.0 genes in this pathway
XU HGF TARGETS REPRESSED BY AKT1 UP	10	7	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 UP	309	199	All SZGR 2.0 genes in this pathway
GROSS HYPOXIA VIA ELK3 DN	156	106	All SZGR 2.0 genes in this pathway
通过ELK3和HIF1A的总缺氧	142	104	All SZGR 2.0 genes in this pathway
NUYTTEN NIPP1 TARGETS UP	769	437	All SZGR 2.0 genes in this pathway
NUYTTEN EZH2 TARGETS UP	1037	673	All SZGR 2.0 genes in this pathway
buytaert光动力疗法压力	811	508	All SZGR 2.0 genes in this pathway
BENPORATH SOX2 TARGETS	734	436	All SZGR 2.0 genes in this pathway
AMIT EGF RESPONSE 120 HELA	69	47	All SZGR 2.0 genes in this pathway
MORI PRE BI LYMPHOCYTE DN	77	49	All SZGR 2.0 genes in this pathway
SHEPARD CRUSH AND BURN MUTANT UP	197	110	All SZGR 2.0 genes in this pathway
ZUCCHI METASTASIS DN	44	29	All SZGR 2.0 genes in this pathway
巴索B淋巴细胞网络	143	96	All SZGR 2.0 genes in this pathway
尼尔森对雄激素的反应	86	61	All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION DN	66	47	All SZGR 2.0 genes in this pathway
FLECHNER PBL KIDNEY TRANSPLANT OK VS DONOR UP	151	100	All SZGR 2.0 genes in this pathway
SANA TNF SIGNALING UP	83	56	All SZGR 2.0 genes in this pathway
Shipp DLBCL与卵泡淋巴瘤	45	30	All SZGR 2.0 genes in this pathway
BROWN MYELOID CELL DEVELOPMENT UP	165	100	All SZGR 2.0 genes in this pathway
松本自然杀手差分	475	313	All SZGR 2.0 genes in this pathway
LEI MYB目标	318	215	All SZGR 2.0 genes in this pathway
NEMETH INFLAMMATORY RESPONSE LPS UP	88	64	All SZGR 2.0 genes in this pathway
GERY CEBP目标	126	90	All SZGR 2.0 genes in this pathway
NPM1的Verhaak AML突变	183	111	All SZGR 2.0 genes in this pathway
Iglesias E2F目标	151	103	All SZGR 2.0 genes in this pathway
TAKAO RESPONSE TO UVB RADIATION UP	86	55	All SZGR 2.0 genes in this pathway
IVANOVA HEMATOPOIESIS LATE PROGENITOR	544	307	All SZGR 2.0 genes in this pathway
外邦紫外线低剂量	27	19	All SZGR 2.0 genes in this pathway
阿尔茨海默氏病dn	1237	837	All SZGR 2.0 genes in this pathway
韦斯顿Vegfa目标6HR	59	38	All SZGR 2.0 genes in this pathway
Ongusaha TP53目标	38	23	All SZGR 2.0 genes in this pathway
HARRIS HYPOXIA	81	64	All SZGR 2.0 genes in this pathway
Kaab心脏中心与心室	249	170	All SZGR 2.0 genes in this pathway
YAMAZAKI TCEB3 TARGETS UP	175	116	All SZGR 2.0 genes in this pathway
马丁内斯对trabectedin的反应	71	49	All SZGR 2.0 genes in this pathway
韦斯顿Vegfa目标12HR	35	23	All SZGR 2.0 genes in this pathway
LINDVALL IMMORTALIZED BY TERT DN	80	56	All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV SCC DN	123	86	All SZGR 2.0 genes in this pathway
韦斯顿Vegfa目标	108	71	All SZGR 2.0 genes in this pathway
LEE AGING NEOCORTEX UP	89	59	All SZGR 2.0 genes in this pathway
外邦紫外线高剂量DN	312	203	All SZGR 2.0 genes in this pathway
MCLACHLAN DENTAL CARIES DN	245	144	All SZGR 2.0 genes in this pathway
GENTILE UV HIGH DOSE UP	25	13	All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE INCIPIENT DN	165	106	All SZGR 2.0 genes in this pathway
GEISS RESPONSE TO DSRNA UP	38	29	All SZGR 2.0 genes in this pathway
KEEN RESPONSE TO ROSIGLITAZONE DN	106	68	All SZGR 2.0 genes in this pathway
JIANG HYPOXIA NORMAL	311	205	All SZGR 2.0 genes in this pathway
韦斯顿·维加法（Weston Vegfa）目标3小时	74	47	All SZGR 2.0 genes in this pathway
JOSEPH RESPONSE TO SODIUM BUTYRATE UP	31	21	All SZGR 2.0 genes in this pathway
麦克拉克兰牙科龋齿	253	147	All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3	720	440	All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 5	482	296	All SZGR 2.0 genes in this pathway
STEARMAN TUMOR FIELD EFFECT UP	36	22	All SZGR 2.0 genes in this pathway
STEARMAN LUNG CANCER EARLY VS LATE DN	61	39	All SZGR 2.0 genes in this pathway
HELLER SILENCED BY METHYLATION UP	282	183	All SZGR 2.0 genes in this pathway
HELLER HDAC TARGETS UP	317	208	All SZGR 2.0 genes in this pathway
Heller HDAC靶向被甲基化的沉默	461	298	All SZGR 2.0 genes in this pathway
MASSARWEH TAMOXIFEN RESISTANCE UP	578	341	All SZGR 2.0 genes in this pathway
Sarrio上皮间质转变DN	154	101	All SZGR 2.0 genes in this pathway
乳腺癌萧述三腔的DN	564	326	All SZGR 2.0 genes in this pathway
BONOME OVARIAN CANCER SURVIVAL OPTIMAL DEBULKING	246	152	All SZGR 2.0 genes in this pathway
LABBE TGFB1 TARGETS UP	102	64	All SZGR 2.0 genes in this pathway
mirlet7a3的Brueckner目标	111	69	All SZGR 2.0 genes in this pathway
PODAR RESPONSE TO ADAPHOSTIN UP	147	98	All SZGR 2.0 genes in this pathway
Chen Hoxa5靶向6小时	10	8	All SZGR 2.0 genes in this pathway
Chen Hoxa5靶向9小时	223	132	All SZGR 2.0 genes in this pathway
康拉德种系干细胞	13	8	All SZGR 2.0 genes in this pathway
WINTER HYPOXIA METAGENE	242	168	All SZGR 2.0 genes in this pathway
MOOTHA PGC	420	269	All SZGR 2.0 genes in this pathway
DAVIES MULTIPLE MYELOMA VS MGUS DN	28	18	All SZGR 2.0 genes in this pathway
Boylan多发性骨髓瘤C簇DN	32	21	All SZGR 2.0 genes in this pathway
BOYLAN MULTIPLE MYELOMA C DN	59	39	All SZGR 2.0 genes in this pathway
TOOKER GEMCITABINE RESISTANCE UP	79	40	All SZGR 2.0 genes in this pathway
RUIZ TNC TARGETS UP	153	107	All SZGR 2.0 genes in this pathway
甜肺癌克拉斯	491	316	All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 36HR UP	221	150	All SZGR 2.0 genes in this pathway
张TLX目标60小时	293	203	All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS UP	108	78	All SZGR 2.0 genes in this pathway
HAN SATB1 TARGETS UP	395	249	All SZGR 2.0 genes in this pathway
LIU VAV3 PROSTATE CARCINOGENESIS UP	89	61	All SZGR 2.0 genes in this pathway
KYNG NORMAL AGING UP	19	11	All SZGR 2.0 genes in this pathway
Kyng Werner综合征	20	10	All SZGR 2.0 genes in this pathway
YAO对孕酮簇1的时间反应1	68	50	All SZGR 2.0 genes in this pathway
MARIADASON RESPONSE TO BUTYRATE CURCUMIN SULINDAC TSA 1	10	7	All SZGR 2.0 genes in this pathway
BAE BRCA1靶向	75	47	All SZGR 2.0 genes in this pathway
Verhaak胶质母细胞瘤间充质	216	130	All SZGR 2.0 genes in this pathway
HIRSCH CELLULAR TRANSFORMATION SIGNATURE UP	242	159	All SZGR 2.0 genes in this pathway
Wang对GSK3抑制剂SB216763的响应向上	397	206	All SZGR 2.0 genes in this pathway
gregory合成致死与伊马替尼	145	83	All SZGR 2.0 genes in this pathway
BRUINS UVC RESPONSE VIA TP53 GROUP B	549	316	All SZGR 2.0 genes in this pathway
DELPUECH FOXO3 TARGETS UP	68	49	All SZGR 2.0 genes in this pathway
Lee BMP2目标	745	475	All SZGR 2.0 genes in this pathway
BILANGES RAPAMYCIN SENSITIVE GENES	39	20	All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3	824	528	All SZGR 2.0 genes in this pathway
CTBP1的Purbey目标不是SATB1 DN	448	282	All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION DN	1080	713	All SZGR 2.0 genes in this pathway
KATSANOU ELAVL1 TARGETS UP	169	105	All SZGR 2.0 genes in this pathway
PEDERSEN METASTASIS BY ERBB2 ISOFORM 4	110	66	All SZGR 2.0 genes in this pathway
HUANG GATA2 TARGETS UP	149	96	All SZGR 2.0 genes in this pathway
DELACROIX RARG BOUND MEF	367	231	All SZGR 2.0 genes in this pathway
DELACROIX RAR TARGETS UP	48	33	All SZGR 2.0 genes in this pathway
GHANDHI BYSTANDER IRRADIATION UP	86	54	All SZGR 2.0 genes in this pathway
Zwang 1类由EGF瞬时诱导	516	308	All SZGR 2.0 genes in this pathway

基因页：SAT1