基因页：SRSF7

Summary？
基因 6432
象征 SRSF7
Synonyms 9G8|AAG3|SFRS7
Description 丝氨酸/精氨酸富含剪接因子7
Reference MIM：600572|HGNC：HGNC：10789|Ensembl:ENSG00000115875|HPRD：08991|Vega：Otthumg00000102076
基因类型 蛋白质编码
Map location 2P22.1
Pascal P值 0.005
Sherlock p-value 0.232

Gene in Data Sources
基因集名称 Method of gene set Description 信息
简历：PGCNP 全基因组协会研究 GWAS

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达（GTEX）

无法使用

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

大脑区域的顶级共表达基因

前10个积极共表达的基因
Gene 皮尔逊的相关性 斯皮尔曼的相关性
FOXO4 0.84 0.80
TRIM41 0.83 0.80
MAP3K11 0.80 0.78
HDAC11 0.79 0.80
kif1c 0.79 0.78
sema3b 0.78 0.79
TFEB 0.77 0.75
UAP1L1 0.76 0.72
plekhb1 0.76 0.69
Rapgef3 0.76 0.72
前10个负共表达基因
Gene 皮尔逊的相关性 斯皮尔曼的相关性
FRG1 -0.61 -0.67
C11orf57 -0.57 -0.64
POLB -0.55 -0.60
txnl1 -0.55 -0.59
C9orf46 -0.55 -0.62
PFDN4 -0.54 -0.62
PPP2R3C -0.54 -0.59
C7orf38 -0.54 -0.57
Yeats4 -0.53 -0.56
DTWD1 -0.53 -0.54

第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去：0000166 nucleotide binding IEA -
GO:0003723 RNA结合 IEA -
去：0005515 蛋白质结合 IPI 15169763
去：0008270 锌离子结合 IEA -
GO：0046872 metal ion binding IEA -
生物过程 去学期 证据 神经关键字 PubMed ID
去：0000398 核mRNA剪接，通过剪接体 经验 12226669
去：0008380 RNA剪接 艾达 8013463
Cellular component 去学期 证据 神经关键字 PubMed ID
去：0005634 nucleus TAS 8013463

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
KEGG SPLICEOSOME 128 72 All SZGR 2.0 genes in this pathway
含有前mRNA的封顶内含子的反应组处理 140 77 All SZGR 2.0 genes in this pathway
成熟转录本向细胞质的反应组传输 54 34 All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION 105 54 All SZGR 2.0 genes in this pathway
Reactome mRNA处理 161 86 All SZGR 2.0 genes in this pathway
Reactome mRNA剪接 111 58 All SZGR 2.0 genes in this pathway
Reactome mRNA剪接次要途径 45 19 All SZGR 2.0 genes in this pathway
Reactome转录 210 127 All SZGR 2.0 genes in this pathway
Reactome mRNA 3末端处理 35 18 All SZGR 2.0 genes in this pathway
REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION 44 22 All SZGR 2.0 genes in this pathway
Onken Uveal黑色素瘤 783 507 All SZGR 2.0 genes in this pathway
GAZDA钻石黑芬贫血红斑dn 493 298 All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS DN 384 230 All SZGR 2.0 genes in this pathway
Bilban B Cll LPL DN 42 25 All SZGR 2.0 genes in this pathway
Mullighan NPM1突变签名1向上 276 165 All SZGR 2.0 genes in this pathway
Mullighan NPM1突变签名2向上 139 83 All SZGR 2.0 genes in this pathway
Mullighan NPM1签名3 341 197 All SZGR 2.0 genes in this pathway
TIEN INTESTINE PROBIOTICS 24HR UP 557 331 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN 209 122 All SZGR 2.0 genes in this pathway
Mayburd对L663536 DN的反应 56 32 All SZGR 2.0 genes in this pathway
多德鼻咽癌DN 1375 806 All SZGR 2.0 genes in this pathway
ENK UV响应表皮增强 293 179 All SZGR 2.0 genes in this pathway
阿霉素DN的Graessmann凋亡 1781 1082 All SZGR 2.0 genes in this pathway
Graessmann对MC和阿霉素DN的反应 770 415 All SZGR 2.0 genes in this pathway
Kong E2F3目标 97 58 All SZGR 2.0 genes in this pathway
XU HGF信令不通过AKT1 48小时DN 20 12 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3公共DN 483 336 All SZGR 2.0 genes in this pathway
TP53和MYC UP的CEBALLOS目标 21 16 All SZGR 2.0 genes in this pathway
通过ELK3 UP总缺氧 209 139 All SZGR 2.0 genes in this pathway
通过HIF1A的总缺氧 77 49 All SZGR 2.0 genes in this pathway
通过ELK3和HIF1A DN的缺氧总缺氧 103 71 All SZGR 2.0 genes in this pathway
Buytaert光动力疗法应力DN 637 377 All SZGR 2.0 genes in this pathway
带有E盒的WEI MYCN目标 795 478 All SZGR 2.0 genes in this pathway
CAFFAREL RESPONSE TO THC 8HR 5 DN 11 8 All SZGR 2.0 genes in this pathway
里克曼肿瘤区分良好，而不是很差 236 139 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY UP 109 69 All SZGR 2.0 genes in this pathway
Benporath ES 1 379 235 All SZGR 2.0 genes in this pathway
Benporath SOX2目标 734 436 All SZGR 2.0 genes in this pathway
Benporath Myc Max目标 775 494 All SZGR 2.0 genes in this pathway
Benporath循环基因 648 385 All SZGR 2.0 genes in this pathway
肯尼CTNNB1靶向 50 30 All SZGR 2.0 genes in this pathway
SANA TNF信号DN 90 57 All SZGR 2.0 genes in this pathway
Bhattacharya胚胎干细胞 89 60 All SZGR 2.0 genes in this pathway
郭十六进制目标 81 54 All SZGR 2.0 genes in this pathway
棕色髓样细胞发育DN 129 86 All SZGR 2.0 genes in this pathway
Zhan V2晚分化基因 45 34 All SZGR 2.0 genes in this pathway
牙槽横纹肌肉瘤 98 64 All SZGR 2.0 genes in this pathway
PAL PRMT5靶向 203 135 All SZGR 2.0 genes in this pathway
Zhu CMV全部 120 89 All SZGR 2.0 genes in this pathway
Zhu CMV 24小时 93 65 All SZGR 2.0 genes in this pathway
Bild E2F3致癌特征 246 153 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 4 307 185 All SZGR 2.0 genes in this pathway
冥界LER HDAC TARGETS DN 292 189 All SZGR 2.0 genes in this pathway
冥界LER HDAC TARGETS SILENCED BY METHYLATION DN 281 179 All SZGR 2.0 genes in this pathway
Boquest干细胞培养与新鲜 425 298 All SZGR 2.0 genes in this pathway
马洛尼对17AAG DN的回应 79 45 All SZGR 2.0 genes in this pathway
对Salirasib dn的Blum响应 342 220 All SZGR 2.0 genes in this pathway
WANG TUMOR INVASIVENESS UP 374 247 All SZGR 2.0 genes in this pathway
Vantveer乳腺癌ESR1 DN 240 153 All SZGR 2.0 genes in this pathway
LEE DIFFERENTIATING T LYMPHOCYTE 200 115 All SZGR 2.0 genes in this pathway
张TLX目标60小时DN 277 166 All SZGR 2.0 genes in this pathway
ZHAN LATE DIFFERENTIATION GENES UP 33 24 All SZGR 2.0 genes in this pathway
Kobayashi EGFR信令24小时DN 251 151 All SZGR 2.0 genes in this pathway
CAIRO LIVER DEVELOPMENT UP 166 105 All SZGR 2.0 genes in this pathway
KYNG WERNER SYNDROM AND NORMAL AGING UP 93 62 All SZGR 2.0 genes in this pathway
由Myc Up监管 72 53 All SZGR 2.0 genes in this pathway
dang myc的目标 143 100 All SZGR 2.0 genes in this pathway
由MYC约束 1103 714 All SZGR 2.0 genes in this pathway
YAO对孕酮簇2的时间反应2 86 50 All SZGR 2.0 genes in this pathway
惠特菲尔德细胞周期G1 S 147 76 All SZGR 2.0 genes in this pathway
马滕斯三维诺蛋白响应DN 841 431 All SZGR 2.0 genes in this pathway
SMAD1和SMAD5 DN抑制Pangas肿瘤 157 106 All SZGR 2.0 genes in this pathway
Pilon KLF1靶向DN 1972 1213 All SZGR 2.0 genes in this pathway
Lee BMP2靶向DN 882 538 All SZGR 2.0 genes in this pathway
FEVR CTNNB1靶向DN 553 343 All SZGR 2.0 genes in this pathway
KRIEG KDM3A TARGETS NOT HYPOXIA 208 107 All SZGR 2.0 genes in this pathway
山乳房干细胞DN 146 88 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 目标位置 miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
miR-181 165 172 1A，M8 HSA-MIR-181Abrain AACAUUCAACGCUGUCGGUGAGU
HSA-MIR-181BSZ aacauucauugcugucggggg
HSA-MIR-181Cbrain AACAUUCAACCUGUCGGUGAGU
HSA-MIR-181Dbrain aacauucauuguugucggggguggguu
miR-188 51 57 M8 HSA-MIR-188 cucccuugcaugguggggu
mir-299-5p 828 835 1A，M8 hsa-miR-299-5p ugguuuaccgucccacauacau
mir-30-5p 36 43 1A，M8 HSA-MIR-30A-5P uguaaaacauccuccugagaag
hsa-miR-30cbrain UGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZ UGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZ uguaaacauccuaccucucagcu
hsa-miR-30e-5p UGUAAACAUCCUUGACUGGA
mir-320 1464 1470 1a hsa-miR-320 aaaagcugggugagaggggcgaa
hsa-miR-320 aaaagcugggugagaggggcgaa
mir-369-3p 45 51 1a hsa - mir - 369 - 3 - p aauauacaugguugaucuuu
miR-374 45 52 1A，M8 HSA-MIR-374 uuauaauacaAccugauaagug
mir-380-5p 95 101 1a hsa-miR-380-5p UGGUUGACCAUAGAACAUGCGC
hsa-miR-563 AGGUUGACAUACGUUUCCC
miR-384 81 88 1A，M8 HSA-MIR-384 auuccuagaaauuguucaua
miR-488 116 122 1a HSA-MIR-488 cccagauauggcacucucucaa
miR-494 226 232 M8 HSA-MIR-494brain ugaaacauacgggaaaccucuu
mir-505 162 168 1a HSA-MIR-505 gucaacuugcugguuccuc