Gene Page:SPATA20
Summary?
| GeneID | 64847 |
| Symbol | SPATA20 |
| Synonyms | hel - s - 98 | SSP411 | Tisp78 |
| Description | spermatogenesis associated 20 |
| Reference | MIM:613939|HGNC:HGNC:26125|Ensembl:ENSG00000006282|HPRD:07961|Vega:OTTHUMG00000162162 |
| Gene type | protein-coding |
| Map location | 17q21.33 |
| Pascal p-value | 0.005 |
| Sherlock p-value | 0.677 |
| eGene | Anterior cingulate cortex BA24 Caudate basal ganglia Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans 元 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs2311336 | chr1 | 15144982 | SPATA20 | 64847 | 0.16 | trans | ||
| rs8068726 | 17 | 48593134 | SPATA20 | ENSG00000006282.15 | 5.143E-7 | 0 | -30533 | gtex_brain_ba24 |
| rs28498091 | 17 | 48597114 | SPATA20 | ENSG00000006282.15 | 5.296E-12 | 0 | -26553 | gtex_brain_ba24 |
| rs9913197 | 17 | 48598291 | SPATA20 | ENSG00000006282.15 | 5.296E-12 | 0 | -25376 | gtex_brain_ba24 |
| rs1106730 | 17 | 48602412 | SPATA20 | ENSG00000006282.15 | 5.037E-11 | 0 | -21255 | gtex_brain_ba24 |
| rs2412327 | 17 | 48602840 | SPATA20 | ENSG00000006282.15 | 5.037E-11 | 0 | -20827 | gtex_brain_ba24 |
| rs16949120 | 17 | 48610732 | SPATA20 | ENSG00000006282.15 | 5.004E-11 | 0 | -12935 | gtex_brain_ba24 |
| rs76487714 | 17 | 48611993 | SPATA20 | ENSG00000006282.15 | 7.113E-11 | 0 | -11674 | gtex_brain_ba24 |
| rs111670942 | 17 | 48612315 | SPATA20 | ENSG00000006282.15 | 1.426E-10 | 0 | -11352 | gtex_brain_ba24 |
| rs79723678 | 17 | 48612433 | SPATA20 | ENSG00000006282.15 | 1.643E-10 | 0 | -11234 | gtex_brain_ba24 |
| rs2306001 | 17 | 48615329 | SPATA20 | ENSG00000006282.15 | 1.152E-10 | 0 | -8338 | gtex_brain_ba24 |
| rs111678638 | 17 | 48619272 | SPATA20 | ENSG00000006282.15 | 1.759E-12 | 0 | -4395 | gtex_brain_ba24 |
| rs112657244 | 17 | 48619290 | SPATA20 | ENSG00000006282.15 | 1.759E-12 | 0 | -4377 | gtex_brain_ba24 |
| rs80277878 | 17 | 48624045 | SPATA20 | ENSG00000006282.15 | 1.755E-12 | 0 | 378 | gtex_brain_ba24 |
| rs9890200 | 17 | 48624523 | SPATA20 | ENSG00000006282.15 | 1.368E-11 | 0 | 856 | gtex_brain_ba24 |
| rs76022681 | 17 | 48625223 | SPATA20 | ENSG00000006282.15 | 1.755E-12 | 0 | 1556 | gtex_brain_ba24 |
| rs200637741 | 17 | 48625307 | SPATA20 | ENSG00000006282.15 | 1.734E-12 | 0 | 1640 | gtex_brain_ba24 |
| rs8076470 | 17 | 48625828 | SPATA20 | ENSG00000006282.15 | 5.026E-12 | 0 | 2161 | gtex_brain_ba24 |
| rs8076632 | 17 | 48625928 | SPATA20 | ENSG00000006282.15 | 2.892E-13 | 0 | 2261 | gtex_brain_ba24 |
| rs878619 | 17 | 48633271 | SPATA20 | ENSG00000006282.15 | 7.091E-12 | 0 | 9604 | gtex_brain_ba24 |
| rs6504675 | 17 | 48634357 | SPATA20 | ENSG00000006282.15 | 7.07E-12 | 0 | 10690 | gtex_brain_ba24 |
| rs198535 | 17 | 48635052 | SPATA20 | ENSG00000006282.15 | 1.257E-9 | 0 | 11385 | gtex_brain_ba24 |
| rs989128 | 17 | 48636534 | SPATA20 | ENSG00000006282.15 | 3.49E-13 | 0 | 12867 | gtex_brain_ba24 |
| rs9906084 | 17 | 48637385 | SPATA20 | ENSG00000006282.15 | 2.211E-13 | 0 | 13718 | gtex_brain_ba24 |
| rs1870581 | 17 | 48637667 | SPATA20 | ENSG00000006282.15 | 1.485E-7 | 0 | 14000 | gtex_brain_ba24 |
| rs111418828 | 17 | 48640419 | SPATA20 | ENSG00000006282.15 | 3.535E-8 | 0 | 16752 | gtex_brain_ba24 |
| rs78549188 | 17 | 48640936 | SPATA20 | ENSG00000006282.15 | 1.568E-7 | 0 | 17269 | gtex_brain_ba24 |
| rs78357287 | 17 | 48643104 | SPATA20 | ENSG00000006282.15 | 5.487E-7 | 0 | 19437 | gtex_brain_ba24 |
| rs9904093 | 17 | 48663004 | SPATA20 | ENSG00000006282.15 | 6.553E-7 | 0 | 39337 | gtex_brain_ba24 |
| rs56134783 | 17 | 48595198 | SPATA20 | ENSG00000006282.15 | 5.05E-7 | 0 | -28469 | gtex_brain_putamen_basal |
| rs28498091 | 17 | 48597114 | SPATA20 | ENSG00000006282.15 | 2.475E-8 | 0 | -26553 | gtex_brain_putamen_basal |
| rs9913197 | 17 | 48598291 | SPATA20 | ENSG00000006282.15 | 1.611E-7 | 0 | -25376 | gtex_brain_putamen_basal |
| rs1106730 | 17 | 48602412 | SPATA20 | ENSG00000006282.15 | 2.744E-7 | 0 | -21255 | gtex_brain_putamen_basal |
| rs2412327 | 17 | 48602840 | SPATA20 | ENSG00000006282.15 | 2.744E-7 | 0 | -20827 | gtex_brain_putamen_basal |
| rs16949120 | 17 | 48610732 | SPATA20 | ENSG00000006282.15 | 2.732E-7 | 0 | -12935 | gtex_brain_putamen_basal |
| rs76487714 | 17 | 48611993 | SPATA20 | ENSG00000006282.15 | 8.541E-11 | 0 | -11674 | gtex_brain_putamen_basal |
| rs111670942 | 17 | 48612315 | SPATA20 | ENSG00000006282.15 | 4.725E-9 | 0 | -11352 | gtex_brain_putamen_basal |
| rs79723678 | 17 | 48612433 | SPATA20 | ENSG00000006282.15 | 9.072E-12 | 0 | -11234 | gtex_brain_putamen_basal |
| rs2306001 | 17 | 48615329 | SPATA20 | ENSG00000006282.15 | 3.111E-13 | 0 | -8338 | gtex_brain_putamen_basal |
| rs4794158 | 17 | 48616114 | SPATA20 | ENSG00000006282.15 | 2.216E-7 | 0 | -7553 | gtex_brain_putamen_basal |
| rs2306002 | 17 | 48617829 | SPATA20 | ENSG00000006282.15 | 1.276E-7 | 0 | -5838 | gtex_brain_putamen_basal |
| rs397818672 | 17 | 48617903 | SPATA20 | ENSG00000006282.15 | 1.275E-7 | 0 | -5764 | gtex_brain_putamen_basal |
| rs111678638 | 17 | 48619272 | SPATA20 | ENSG00000006282.15 | 4.73E-14 | 0 | -4395 | gtex_brain_putamen_basal |
| rs112657244 | 17 | 48619290 | SPATA20 | ENSG00000006282.15 | 4.72E-14 | 0 | -4377 | gtex_brain_putamen_basal |
| rs1122634 | 17 | 48621365 | SPATA20 | ENSG00000006282.15 | 1.231E-7 | 0 | -2302 | gtex_brain_putamen_basal |
| rs397856670 | 17 | 48621453 | SPATA20 | ENSG00000006282.15 | 5.489E-8 | 0 | -2214 | gtex_brain_putamen_basal |
| rs80277878 | 17 | 48624045 | SPATA20 | ENSG00000006282.15 | 5.848E-14 | 0 | 378 | gtex_brain_putamen_basal |
| rs9890200 | 17 | 48624523 | SPATA20 | ENSG00000006282.15 | 4.522E-16 | 0 | 856 | gtex_brain_putamen_basal |
| rs76022681 | 17 | 48625223 | SPATA20 | ENSG00000006282.15 | 8.858E-14 | 0 | 1556 | gtex_brain_putamen_basal |
| rs200637741 | 17 | 48625307 | SPATA20 | ENSG00000006282.15 | 9.235E-14 | 0 | 1640 | gtex_brain_putamen_basal |
| rs8076470 | 17 | 48625828 | SPATA20 | ENSG00000006282.15 | 6.655E-13 | 0 | 2161 | gtex_brain_putamen_basal |
| rs8076632 | 17 | 48625928 | SPATA20 | ENSG00000006282.15 | 9.708E-16 | 0 | 2261 | gtex_brain_putamen_basal |
| rs878619 | 17 | 48633271 | SPATA20 | ENSG00000006282.15 | 9.648E-13 | 0 | 9604 | gtex_brain_putamen_basal |
| rs6504675 | 17 | 48634357 | SPATA20 | ENSG00000006282.15 | 1.913E-12 | 0 | 10690 | gtex_brain_putamen_basal |
| rs198535 | 17 | 48635052 | SPATA20 | ENSG00000006282.15 | 3.541E-10 | 0 | 11385 | gtex_brain_putamen_basal |
| rs989128 | 17 | 48636534 | SPATA20 | ENSG00000006282.15 | 2.064E-15 | 0 | 12867 | gtex_brain_putamen_basal |
| rs9906084 | 17 | 48637385 | SPATA20 | ENSG00000006282.15 | 1.55E-15 | 0 | 13718 | gtex_brain_putamen_basal |
| rs1870581 | 17 | 48637667 | SPATA20 | ENSG00000006282.15 | 4.457E-9 | 0 | 14000 | gtex_brain_putamen_basal |
| rs111418828 | 17 | 48640419 | SPATA20 | ENSG00000006282.15 | 9.274E-10 | 0 | 16752 | gtex_brain_putamen_basal |
| rs78549188 | 17 | 48640936 | SPATA20 | ENSG00000006282.15 | 5.273E-9 | 0 | 17269 | gtex_brain_putamen_basal |
| rs78357287 | 17 | 48643104 | SPATA20 | ENSG00000006282.15 | 7.778E-7 | 0 | 19437 | gtex_brain_putamen_basal |
| rs76053544 | 17 | 48659540 | SPATA20 | ENSG00000006282.15 | 8.139E-7 | 0 | 35873 | gtex_brain_putamen_basal |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ONKEN UVEAL MELANOMA UP | 783 | 507 | All SZGR 2.0 genes in this pathway |
| BASAKI YBX1 TARGETS DN | 384 | 230 | All SZGR 2.0 genes in this pathway |
| FARMER BREAST CANCER BASAL VS LULMINAL | 330 | 215 | All SZGR 2.0 genes in this pathway |
| NIKOLSKY BREAST CANCER 17Q21 Q25 AMPLICON | 335 | 181 | All SZGR 2.0 genes in this pathway |
| JIANG HYPOXIA NORMAL | 311 | 205 | All SZGR 2.0 genes in this pathway |
| WEST ADRENOCORTICAL TUMOR DN | 546 | 362 | All SZGR 2.0 genes in this pathway |
| AGUIRRE PANCREATIC CANCER COPY NUMBER UP | 298 | 174 | All SZGR 2.0 genes in this pathway |
| MARTENS TRETINOIN RESPONSE UP | 857 | 456 | All SZGR 2.0 genes in this pathway |
| JOHNSTONE PARVB TARGETS 3 UP | 430 | 288 | All SZGR 2.0 genes in this pathway |