SZGR2 - Beplay体育中心

概括?

基因	6872
象征	TAF1
Synonyms	BA2R \| CCG1 \| CCGS \| DYT3 \| DYT3/TAF1 \| KAT4 \| MRXS33 \| N-TAF1 \| NSCL2 \| NSCL2 \| of \| P250 \| TAF（II）250 \| TAF2A \| TAFII-250 \| TAFII-250 \| TAFIII250 \| TAFII250 \| XDP
Description	TATA-box binding protein associated factor 1
Reference	MIM:313650\|HGNC:HGNC:11535\|ENSEMBL：ENSG00000147133\|HPRD:02436\|Vega:OTTHUMG00000022723
Gene type	protein-coding
Map location	XQ13.1
Fetal beta	0.676
Support	Ascano FMRP targets

数据源中的基因

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	系统搜索PubMed的基因共现ring with SCZ keywords. A total of 3027 genes were included.
文学	High-throughput literature-search	与精神分裂症关键词共同存在：精神分裂症，精神分裂症	Click to show details

第一节遗传学和表观遗传学注释

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

脚注：
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

大脑区域没有共表达基因

第四节。蛋白质蛋白相互作用注释

互动者	Aliases B	Official full name B	Experimental	资源	PubMed ID
ASF1A	CGI-98 \| CIA \| DKFZp547E2110 \| HSPC146	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	-	HPRD	12093919
ASF1A	CGI-98 \| CIA \| DKFZp547E2110 \| HSPC146	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	CIA interacts with TAFII250.	BIND	12093919
ASF1B	CIA-II \| FLJ10604	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	-	HPRD	12842904
BAX	BCl2L4	BCL2-associated X protein	TAF1（TAFII250）与BAX启动子相互作用。	BIND	15710329
CCNA2	CCN1 \|CCNA	细胞周期蛋白A2	-	HPRD,BioGRID	9660973
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	TAFII250 interacts with Cyclin D1. This interaction was modelled on a demonstrated interaction between TAFII250 from human and Cyclin D1 from mouse.	BIND	11126356
CCND1	BCL1 \| D11S287E \| PRAD1 \| U21B31	cyclin D1	-	HPRD,BioGRID	9926939\|11126356
EDF1	EDF-1 \|MBF1 \|MGC9058	endothelial differentiation-related factor 1	-	HPRD	12040021
ewsR1	ews	Ewing sarcoma breakpoint region 1	-	HPRD	9488465
FOS	AP-1 \|c-fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	-	HPRD,BioGRID	8065335
GTF2A1	MGC129969 \| MGC129970 \| TF2A1 \| TFIIA	通用转录因子IIA，1，19/37KDA	-	HPRD,BioGRID	11278496
GTF2B	TF2B \| TFIIB	general transcription factor IIB	-	HPRD	1876184
GTF2E1	FE \| TF2E1 \| TFIIE-A	通用转录因子IIE，多肽1，α56KDA	Reconstituted Complex	BioGRID	7926747
GTF2F1	BTF4 \| RAP74 \| TF2F1 \| TFIIF	general transcription factor IIF, polypeptide 1, 74kDa	Biochemical Activity in vitro in vivo Reconstituted Complex	BioGRID	7590250\|8625415 \|9482861\|9660973 \|9858607
GTF2F1	BTF4 \| RAP74 \| TF2F1 \| TFIIF	general transcription factor IIF, polypeptide 1, 74kDa	-	HPRD	7590250\|8625415 \|9660973\|10428810
Hist3H3	H3.4 \|H3/g \|H3FT \|H3T \|MGC126886 \|MGC126888	组蛋白簇3，H3	-	HPRD	8980232
HMGB1	DKFZP686A04236 \|HMG1 \|HMG3 \|SBP-1	high-mobility group box 1	-	HPRD	9880542
HSF1	HSTF1	heat shock transcription factor 1	-	HPRD	11005381
JUN	AP-1 \|AP1 \| c-Jun	Jun Oncogene	-	HPRD,BioGRID	11316804
MDM2	HDMX \| MGC71221 \| hdm2	Mdm2 p53 binding protein homolog (mouse)	-	HPRD,BioGRID	9388200
MSX1	HOX7 \|HYD1	msh homeobox 1	-	HPRD,BioGRID	8700832
PAX6	AN \| AN2 \| D11S812E \| MGC17209 \| MGDA \| WAGR	配对框6	Affinity Capture-Western	BioGRID	10359315
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	TAFII250 interacts with Rb.	BIND	11126356
RB1	OSRC \| RB \| p105-Rb \| pRb \| pp110	retinoblastoma 1	-	HPRD,BioGRID	7724524\|9242374 \|9858607
RBL1	CP107 \| MGC40006 \| PRB1 \| p107	retinoblastoma-like 1 (p107)	-	HPRD,BioGRID	9242374
RBL2	FLJ26459 \|P130 \|RB2	retinoblastoma-like 2 (p130)	-	HPRD,BioGRID	9242374
RELA	MGC131774 \| NFKB3 \| p65	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	-	HPRD,BioGRID	9584164
SUB1	MGC102747 \| P15 \| PC4 \| p14	Sub1同源物（S. cerevisiae）	-	HPRD	9482861
TAF1	BA2R \| CCG1 \| CCGS \| DYT3 \| KAT4 \| N-TAF1 \| NSCL2 \| OF \| P250 \| TAF2A \| TAFII250	TAF1RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	-	HPRD	8650542
TAF10	taf2A \| TAF2H \| TAFII30	TAF10 RNA聚合酶II，TATA盒结合蛋白（TBP）相关因子，30KDA	-	HPRD	7923369
TAF15	Npl3 \| RBP56 \| TAF2N \| TAFII68 \| hTAFII68	TAF15RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	-	HPRD	8663456\|9488465
taf2	CIF150 \| TAF2B \| TAFII150	TAF2 RNA聚合酶II，TATA盒结合蛋白（TBP）相关因子，150KDA	-	HPRD,BioGRID	10469661
TAF4	FLJ41943 \| TAF2C \| TAF2C1 \| TAF4A \| TAFII130 \| TAFII135	TAF4RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	-	HPRD,BioGRID	11564872
taf4b	taf2c2 \|TAFII105	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	taf4b(hTAF4b) interacts with an uspecified isoform of TAF1 (hTAF1).	BIND	15601843
TAF5	taf2d \|TAFII100	TAF5 RNA聚合酶II，TATA盒结合蛋白（TBP）相关因子，100KDA	-	HPRD,BioGRID	9045704
TAF6	DKFZp781E21155 \| MGC:8964 \| TAF2E \| TAFII70 \| TAFII80 \| TAFII85	TAF6RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa	-	HPRD,BioGRID	7667268
TAF7	taf2F \| TAFII55	TAF7RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	-	HPRD,BioGRID	11592977
TAF7L	FLJ23157 \|taf2q \|DJ738A13.1	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa	两个杂交	BioGRID	12665565
TAF8	43 \| FLJ32821 \| II \| TAF \| TAFII43 \| TBN	TAF8RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa	-	HPRD	14580349
TBP	gtf2d \|GTF2D1 \|MGC117320 \|MGC126054 \|MGC126055 \|SCA17 \|tfiid	塔塔盒结合蛋白	-	HPRD,BioGRID	7680771
TP53	FLJ92943 \|LFS1 \|trp53 \|p53	tumor protein p53	-	HPRD	7809597
TP53	FLJ92943 \|LFS1 \|trp53 \|p53	tumor protein p53	Affinity Capture-Western	BioGRID	10359315
UBTF	NOR-90 \| UBF	upstream binding transcription factor, RNA polymerase I	-	HPRD,BioGRID	12498690

V.途径注释

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG BASAL TRANSCRIPTION FACTORS	36	24	该途径中的所有SZGR 2.0基因
BIOCARTA P53HYPOXIA PATHWAY	23	21	该途径中的所有SZGR 2.0基因
PID RB 1 Pathway	65	46	该途径中的所有SZGR 2.0基因
Reactome RNA Pol II转录	105	54	该途径中的所有SZGR 2.0基因
Reactome RNA Pol II转录PRE INITIATION AND PROMOTER OPENING	41	21	该途径中的所有SZGR 2.0基因
REACTOME TRANSCRIPTION	210	127	该途径中的所有SZGR 2.0基因
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS	61	32	该途径中的所有SZGR 2.0基因
REACTOME HIV INFECTION	207	122	该途径中的所有SZGR 2.0基因
Reactome HIV生命周期	125	69	该途径中的所有SZGR 2.0基因
REACTOME LATE PHASE OF HIV LIFE CYCLE	104	61	该途径中的所有SZGR 2.0基因
GARY CD5 TARGETS UP	473	314	该途径中的所有SZGR 2.0基因
王攀登目标	269	146	该途径中的所有SZGR 2.0基因
ginestier乳腺癌20q13扩增	119	66	该途径中的所有SZGR 2.0基因
ODONNELL METASTASIS UP	82	58	该途径中的所有SZGR 2.0基因
GRUETZMANN PANCREATIC CANCER DN	203	134	该途径中的所有SZGR 2.0基因
Pujana ATM PCC网络	1442	892	该途径中的所有SZGR 2.0基因
Schaeffer前列腺开发6小时DN	514	330	该途径中的所有SZGR 2.0基因
TARTE PLASMA CELL VS PLASMABLAST UP	398	262	该途径中的所有SZGR 2.0基因
HOFMANN CELL LYMPHOMA DN	39	29	该途径中的所有SZGR 2.0基因
YAGI AML SURVIVAL	129	87	该途径中的所有SZGR 2.0基因
BROWNE HCMV INFECTION 48HR DN	504	323	该途径中的所有SZGR 2.0基因
HEDENFALK BREAST CANCER BRCA1 VS BRCA2	163	113	该途径中的所有SZGR 2.0基因
在胰腺癌中被甲基化沉默的Sato 1	419	273	该途径中的所有SZGR 2.0基因
FIRESTEIN PROLIFERATION	175	125	该途径中的所有SZGR 2.0基因
Yagi AML带有Inv 16易位	422	277	该途径中的所有SZGR 2.0基因
GABRIELY MIR21 TARGETS	289	187	该途径中的所有SZGR 2.0基因
Bruins通过TP53组D的UVC响应	280	158	该途径中的所有SZGR 2.0基因

Gene Page:TAF1