Gene Page:TAF4

Summary?
GeneID 6874
Symbol TAF4
Synonyms TAF2C|TAF2C1|TAF4A|TAFII130|TAFII135
Description TATA-box binding protein associated factor 4
Reference MIM:601796|HGNC:HGNC:11537|Ensembl:ENSG00000130699|HPRD:11797|Vega:OTTHUMG00000032893
Gene type protein-coding
Map location 20q13.33
Pascal p-value 0.214
Sherlock p-value 0.023
Fetal beta 1.114
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs2068673 chr12 60333402 TAF4 6874 0.02 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
相约: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B Experimental Source PubMed ID
AHR - aryl hydrocarbon receptor AHR interacts with TAF4. BIND 15641800
ATF7 ATFA | MGC57182 activating transcription factor 7 TAF4 interacts ATF7. BIND 15735663
CBX5 HP1 | HP1A chromobox homolog 5 (HP1 alpha homolog, Drosophila) - HPRD,BioGRID 11959914
CREM ICER | MGC111110 | MGC17881 | MGC41893 | hCREM-2 cAMP responsive element modulator - HPRD,BioGRID 10409662
GTF2A1 MGC129969 | MGC129970 | TF2A1 | TFIIA general transcription factor IIA, 1, 19/37kDa - HPRD 11564872
GTF2A2 HsT18745 | TF2A2 | TFIIA general transcription factor IIA, 2, 12kDa - HPRD,BioGRID 11564872
HTT 高清| IT15 huntingtin TAFII130 interacts with htt. BIND 11988536
HTT 高清| IT15 huntingtin - HPRD 11988536
KAT2A GCN5 | GCN5L2 | MGC102791 | PCAF-b | hGCN5 K(lysine) acetyltransferase 2A Affinity Capture-Western BioGRID 11406595
SAP130 FLJ12761 Sin3A-associated protein, 130kDa Affinity Capture-Western BioGRID 11406595
SP1 - Sp1 transcription factor - HPRD,BioGRID 9742090
SUPT3H SPT3 | SPT3L suppressor of Ty 3 homolog (S. cerevisiae) Affinity Capture-Western BioGRID 11406595
TAF1 BA2R | CCG1 | CCGS | DYT3 | KAT4 | N-TAF1 | NSCL2 | OF | P250 | TAF2A | TAFII250 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa - HPRD,BioGRID 11564872
TAF10 TAF2A | TAF2H | TAFII30 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa Affinity Capture-Western BioGRID 11406595
TAF12 TAF2J | TAFII20 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa Far Western BioGRID 11564872
TAF4 FLJ41943 | TAF2C | TAF2C1 | TAF4A | TAFII130 | TAFII135 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa Far Western BioGRID 11564872
TAF5 TAF2D | TAFII100 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa Affinity Capture-Western BioGRID 11406595
TAF8 43 | FLJ32821 | II | TAF | TAFII43 | TBN TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa Far Western BioGRID 11564872
TBP GTF2D | GTF2D1 | MGC117320 | MGC126054 | MGC126055 | SCA17 | TFIID TATA box binding protein Affinity Capture-Western
Co-purification		 BioGRID 9153318|12665565


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG BASAL TRANSCRIPTION FACTORS 36 24 All SZGR 2.0 genes in this pathway
KEGG HUNTINGTONS DISEASE 185 109 All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION 105 54 All SZGR 2.0 genes in this pathway
REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING 41 21 All SZGR 2.0 genes in this pathway
REACTOME TRANSCRIPTION 210 127 All SZGR 2.0 genes in this pathway
REACTOME RNA POL II PRE TRANSCRIPTION EVENTS 61 32 All SZGR 2.0 genes in this pathway
REACTOME HIV INFECTION 207 122 All SZGR 2.0 genes in this pathway
REACTOME HIV LIFE CYCLE 125 69 All SZGR 2.0 genes in this pathway
REACTOME LATE PHASE OF HIV LIFE CYCLE 104 61 All SZGR 2.0 genes in this pathway
NAGY TFTC COMPONENTS HUMAN 19 11 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483 336 All SZGR 2.0 genes in this pathway
PUJANA BRCA1 PCC NETWORK 1652 1023 All SZGR 2.0 genes in this pathway
PUJANA BRCA2 PCC NETWORK 423 265 All SZGR 2.0 genes in this pathway
PUJANA CHEK2 PCC NETWORK 779 480 All SZGR 2.0 genes in this pathway
NIKOLSKY BREAST CANCER 20Q12 Q13 AMPLICON 149 76 All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN 225 163 All SZGR 2.0 genes in this pathway
KAYO AGING MUSCLE DN 123 76 All SZGR 2.0 genes in this pathway
BROWNE HCMV INFECTION 10HR UP 101 69 All SZGR 2.0 genes in this pathway
KRASNOSELSKAYA ILF3 TARGETS DN 46 38 All SZGR 2.0 genes in this pathway
BILD E2F3 ONCOGENIC SIGNATURE 246 153 All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER UP 298 174 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
PURBEY CTBP1没有SATB1的目标 344 215 All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION UP 570 339 All SZGR 2.0 genes in this pathway