Gene Page:UGT2B15

Summary?
GeneID 7366
Symbol UGT2B15
Synonyms HLUG4|UDPGT 2B8|UDPGT2B15|UDPGTH3|UGT2B8
Description UDP glucuronosyltransferase family 2 member B15
Reference MIM:600069|HGNC:HGNC:12546|Ensembl:ENSG00000196620|HPRD:07192|Vega:OTTHUMG00000161507
Gene type protein-coding
Map location 4q13
Pascal p-value 0.703
DMG 1 (# studies)

Gene in Data Sources
Gene set name Method of gene set Description Info
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg04016992 4 69537806 UGT2B15 4.741E-4 0.301 0.046 DMG:Wockner_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
LRPAP1 0.74 0.64
AC005512.1 0.72 0.57
TESC 0.72 0.63
ADRA2C 0.70 0.47
HPCA 0.70 0.57
RGS14 0.69 0.65
WNT6 0.69 0.47
GOLT1A 0.68 0.58
TMPRSS6 0.67 0.28
TH 0.67 0.61
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
KIAA1949 -0.28 -0.25
MYCN -0.28 -0.14
SCUBE1 -0.28 -0.34
CSRP2 -0.28 -0.34
TUBB2B -0.28 -0.31
SH2B2 -0.28 -0.38
GJC1 -0.27 -0.26
MPPED1 -0.27 -0.17
ZNF124 -0.27 -0.19
TLE3 -0.27 -0.17

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
KEGG PENTOSE AND GLUCURONATE INTERCONVERSIONS 28 17 All SZGR 2.0 genes in this pathway
KEGG ASCORBATE AND ALDARATE METABOLISM 25 17 All SZGR 2.0 genes in this pathway
KEGG STEROID HORMONE BIOSYNTHESIS 55 30 All SZGR 2.0 genes in this pathway
KEGG STARCH AND SUCROSE METABOLISM 52 33 All SZGR 2.0 genes in this pathway
KEGG RETINOL METABOLISM 64 37 All SZGR 2.0 genes in this pathway
KEGG PORPHYRIN AND CHLOROPHYLL METABOLISM 41 23 All SZGR 2.0 genes in this pathway
KEGG METABOLISM OF XENOBIOTICS BY CYTOCHROME P450 70 44 All SZGR 2.0 genes in this pathway
KEGG DRUG METABOLISM CYTOCHROME P450 72 47 All SZGR 2.0 genes in this pathway
KEGG DRUG METABOLISM OTHER ENZYMES 51 27 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS TOP50 UP 38 27 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367 220 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 MUTATED SIGNATURE 1 UP 276 165 All SZGR 2.0 genes in this pathway
MULLIGHAN NPM1 SIGNATURE 3 UP 341 197 All SZGR 2.0 genes in this pathway
SABATES COLORECTAL ADENOMA DN 291 176 All SZGR 2.0 genes in this pathway
GOZGIT ESR1 TARGETS DN 781 465 All SZGR 2.0 genes in this pathway
GRUETZMANN PANCREATIC CANCER DN 203 134 All SZGR 2.0 genes in this pathway
CEBALLOS TARGETS OF TP53 AND MYC DN 38 31 All SZGR 2.0 genes in this pathway
CERVERA SDHB TARGETS 1 UP 118 66 All SZGR 2.0 genes in this pathway
BECKER TAMOXIFEN RESISTANCE UP 50 36 All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546 351 All SZGR 2.0 genes in this pathway
HSIAO LIVER SPECIFIC GENES 244 154 All SZGR 2.0 genes in this pathway
YEGNASUBRAMANIAN PROSTATE CANCER 128 60 All SZGR 2.0 genes in this pathway
SMID BREAST CANCER BASAL DN 701 446 All SZGR 2.0 genes in this pathway
BOCHKIS FOXA2 TARGETS 425 261 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER SURVIVAL UP 185 112 All SZGR 2.0 genes in this pathway
CHAUHAN RESPONSE TO METHOXYESTRADIOL DN 102 65 All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305 895 All SZGR 2.0 genes in this pathway
COULOUARN TEMPORAL TGFB1 SIGNATURE DN 138 99 All SZGR 2.0 genes in this pathway
YAMASHITA LIVER CANCER STEM CELL DN 76 51 All SZGR 2.0 genes in this pathway
DANG REGULATED BY MYC DN 253 192 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS UP 221 135 All SZGR 2.0 genes in this pathway
HOFFMAN CLOCK TARGETS UP 11 7 All SZGR 2.0 genes in this pathway
VANLOO SP3 TARGETS DN 89 47 All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS DN 109 71 All SZGR 2.0 genes in this pathway
SERVITJA LIVER HNF1A TARGETS DN 157 105 All SZGR 2.0 genes in this pathway
PEDERSEN METASTASIS BY ERBB2 ISOFORM 4 110 66 All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL DN 308 187 All SZGR 2.0 genes in this pathway