Gene Page:vldlr

Summary？
基因 7436
象征 vldlr
Synonyms CAMRQ1|CARMQ1|CHRMQ1|VLDLRCH
Description 非常低密度脂蛋白受体
Reference MIM：192977|HGNC：HGNC：12698|ENSEMBL：ENSG00000147852|HPRD：01895|Vega：Otthumg0000000019447
基因类型 蛋白质编码
Map location 9p24
Pascal p-value 0.555
Sherlock p-value 0.316
胎儿β 1.542
主持人 Myers' cis & trans
元
Support Ascano FMRP targets

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp Genome-wide Association Study GWAS
PMID：cooccur High-throughput literature-search PubMed中的系统搜索与SCZ关键字共发生的基因。总共包括3027个基因。
Literature High-throughput literature-search 与精神分裂症关键词共同存在：精神分裂症，精神分裂症，精神分裂症 点击显示详细信息
go_annotation 将与神经相关的关键字映射到基因本体论注释 与神经相关的关键字的命中：1
Network Shortest path distance of core genes in the Human protein-protein interaction network Contribution to shortest path in PPI network: 0.8074

Section I. Genetics and epigenetics annotation

@eQTL注释

SNP ID 染色体 位置 主持人 Gene Entrez ID pvalue QVALUE TSS距离 EQTL类型
rs10757235 Chr9 2180535 vldlr 7436 0.19 顺式
RS7875236 Chr9 2185323 vldlr 7436 0.18 顺式

第二节。转录组注释

一般基因表达（GTEX）

Not available

Devlopment期间的基因表达（BrainCloud）

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions


第三节。基因本体论注释

分子功能 去学期 证据 神经关键字 PubMed ID
去：0005041 低密度脂蛋白受体活性 TAS 10380922
GO:0004872 受体活性 IEA -
去：0005509 calcium ion binding IEA -
去：0005319 脂质转运蛋白活性 IEA -
生物过程 去学期 证据 神经关键字 PubMed ID
GO:0007399 nervous system development TAS 神经突（GO期限：5） 10380922
GO:0007165 信号转导 TAS 10380922
去：0008202 类固醇代谢过程 IEA -
去：0008203 胆固醇代谢过程 IEA -
去：0007613 memory TAS 7550352
去：0006629 脂质代谢过程 IEA -
去：0006869 脂质运输 IEA -
去：0006897 内吞作用 IEA -
GO:0045860 蛋白激酶活性的阳性调节 IEA -
Cellular component 去学期 证据 神经关键字 PubMed ID
去：0005624 membrane fraction 艾达 15082773
去：0016020 membrane IEA -
GO：0016021 膜不可或缺 IEA -
GO:0005905 涂层坑 IEA -
去：0005886 plasma membrane TAS 10380922

Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
PID REELIN PATHWAY 29 29 All SZGR 2.0 genes in this pathway
PID LIS1途径 28 22 All SZGR 2.0 genes in this pathway
PID UPA UPAR PATHWAY 42 30 All SZGR 2.0 genes in this pathway
中村肿瘤区周围与中央DN 634 384 All SZGR 2.0 genes in this pathway
Onken Uveal黑色素瘤 783 507 All SZGR 2.0 genes in this pathway
Gary CD5目标 473 314 All SZGR 2.0 genes in this pathway
Horiuchi WTAP靶向 306 188 All SZGR 2.0 genes in this pathway
BASAKI YBX1 TARGETS DN 384 230 All SZGR 2.0 genes in this pathway
VECCHI GASTRIC CANCER EARLY DN 367 220 All SZGR 2.0 genes in this pathway
OSWALD HEMATOPOIETIC STEM CELL IN COLLAGEN GEL DN 275 168 All SZGR 2.0 genes in this pathway
ELVIDGE HYPOXIA UP 171 112 All SZGR 2.0 genes in this pathway
DMOG的Elvidge缺氧 130 85 All SZGR 2.0 genes in this pathway
Elvidge Hif1a靶向​​DN 91 58 All SZGR 2.0 genes in this pathway
Elvidge HIF1A和HIF2A靶向DN 104 72 All SZGR 2.0 genes in this pathway
Gozgit ESR1靶向DN 781 465 All SZGR 2.0 genes in this pathway
ENK UV响应表皮增强 293 179 All SZGR 2.0 genes in this pathway
Gaussmann MLL AF4融合目标E DN 22 12 All SZGR 2.0 genes in this pathway
TAKADA GASTRIC CANCER COPY NUMBER DN 29 15 All SZGR 2.0 genes in this pathway
哈马凋亡通过Trail Up 584 356 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 XPCS DN 88 71 All SZGR 2.0 genes in this pathway
FARMER BREAST CANCER APOCRINE VS LUMINAL 326 213 All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE DN 712 443 All SZGR 2.0 genes in this pathway
Hernandez异常有丝分裂由DOCETACEL 2NM上升 81 57 All SZGR 2.0 genes in this pathway
dacosta ercc3等位基因XPCS vs TTD DN 36 27 All SZGR 2.0 genes in this pathway
Dacosta UV响应通过ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER UP 227 137 All SZGR 2.0 genes in this pathway
SASAI对肿瘤转移的耐药性 50 31 All SZGR 2.0 genes in this pathway
GROSS ELK3 TARGETS DN 32 17 All SZGR 2.0 genes in this pathway
通过ELK3 DN的缺氧总缺氧 156 106 All SZGR 2.0 genes in this pathway
里克曼肿瘤分化了井和DN不良 382 224 All SZGR 2.0 genes in this pathway
里克曼肿瘤分化中等程度与不良 121 71 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP 487 286 All SZGR 2.0 genes in this pathway
Schaeffer Sox9在前列腺开发中的目标 21 19 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
JECHLINGER EPITHELIAL TO MESENCHYMAL TRANSITION UP 71 51 All SZGR 2.0 genes in this pathway
BYSTRYKH HEMATOPOIESIS STEM CELL QTL TRANS 882 572 All SZGR 2.0 genes in this pathway
马纳洛缺氧 207 145 All SZGR 2.0 genes in this pathway
Zhan多发性骨髓瘤CD1 vs CD2 UP 66 47 All SZGR 2.0 genes in this pathway
Li Wilms肿瘤与胎儿肾脏1 182 119 All SZGR 2.0 genes in this pathway
NPM1突变DN的Verhaak AML 246 180 All SZGR 2.0 genes in this pathway
Browne HCMV感染16小时 225 139 All SZGR 2.0 genes in this pathway
HEDENFALK BREAST CANCER HEREDITARY VS SPORADIC 50 32 All SZGR 2.0 genes in this pathway
阿尔茨海默氏病dn 1237 837 All SZGR 2.0 genes in this pathway
Kayo卡路里限制肌肉DN 87 59 All SZGR 2.0 genes in this pathway
伊万诺娃造血干细胞 254 164 All SZGR 2.0 genes in this pathway
Kayo衰老肌肉DN 123 76 All SZGR 2.0 genes in this pathway
GAJATE RESPONSE TO TRABECTEDIN UP 67 45 All SZGR 2.0 genes in this pathway
Hedenfalk乳腺癌BRCA1与BRCA2 163 113 All SZGR 2.0 genes in this pathway
Dazard对UV NHEK DN的反应 318 220 All SZGR 2.0 genes in this pathway
DAZARD UV RESPONSE CLUSTER G6 153 112 All SZGR 2.0 genes in this pathway
RAMPON ENRICHED LEARNING ENVIRONMENT LATE UP 22 16 All SZGR 2.0 genes in this pathway
Wang Smarce1靶向 280 183 All SZGR 2.0 genes in this pathway
Gerhold脂肪形成 49 40 All SZGR 2.0 genes in this pathway
Krige对Tosedostat 6小时的反应 953 554 All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP 783 442 All SZGR 2.0 genes in this pathway
Smid乳腺癌基础 648 398 All SZGR 2.0 genes in this pathway
罗斯白血病与MLL融合 78 49 All SZGR 2.0 genes in this pathway
AGUIRRE PANCREATIC CANCER COPY NUMBER DN 238 145 All SZGR 2.0 genes in this pathway
Han Satb1靶向DN 442 275 All SZGR 2.0 genes in this pathway
Valk AML群集13 30 20 All SZGR 2.0 genes in this pathway
清肝癌子类CTNNB1 UP 176 110 All SZGR 2.0 genes in this pathway
YAGI AML WITH T 8 21 TRANSLOCATION 368 247 All SZGR 2.0 genes in this pathway
由MYC DN监管 253 192 All SZGR 2.0 genes in this pathway
WONG ADULT TISSUE STEM MODULE 721 492 All SZGR 2.0 genes in this pathway
Qi缺氧 140 96 All SZGR 2.0 genes in this pathway
Ohguchi肝HNF4A靶向 44 30 All SZGR 2.0 genes in this pathway
CARD MIR302A TARGETS 77 62 All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS UP 745 475 All SZGR 2.0 genes in this pathway
SERVITJA ISLET HNF1A TARGETS DN 109 71 All SZGR 2.0 genes in this pathway
杨Bcl3靶向 364 236 All SZGR 2.0 genes in this pathway
FORTSCHEGGER PHF8目标了 279 155 All SZGR 2.0 genes in this pathway
农民乳腺癌簇3 16 12 All SZGR 2.0 genes in this pathway

第六节。microRNA注释

mirna家族 Target position miRNA ID mirna seq
UTR开始 UTR结束 匹配方法
mir-101 564 570 1a hsa-miR-101 uacaguacugauaacugaag
miR-135 283 290 1A，M8 HSA-MIR-135A UAUGGCUUUUUAUUCCUAUGUGA
HSA-MIR-135B Uauggcuuuucauuccuaugug
miR-144 564 570 1a HSA-MIR-144 UACAGUAUAGAUGAUGUACUAG
miR-149 64 70 M8 HSA-MIR-149brain Ucuggcuccucuucuucacuccc
miR-17-5p/20/93.mr/106/519.d 386 392 M8 HSA-MIR-17-5P caaagugcuuacugcagguagu
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ caaagugcuugugcagguag
HSA-MIR-519D caaagugccucccuuuagugugu
HSA-MIR-17-5P caaagugcuuacugcagguagu
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ caaagugcuugugcagguag
HSA-MIR-519D caaagugccucccuuuagugugu
miR-182 477 484 1A，M8 HSA-MIR-182 uuuggcaaugguagaacucaca
miR-200bc/429 243 249 M8 hsa-miR-200b UAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200c UAAUACUGCCGGGUAAUGAUGG
hsa-miR-429 UAAUACUGUCUGGUAAAACCGU
mir-219 369 375 1a hsa-miR-219brain UGAUUGUCCAAACGCAAUUCU
miR-26 142 148 M8 HSA-MIR-26Abrain UUCAAGUAAUCCAGGAUAGGC
HSA-MIR-26BSZ UUCAAGUAAUUCAGGAUAGGUU
mir-299-5p 596 602 1a hsa-miR-299-5p ugguuuaccgucccacauacau
mir-326 361 368 1A，M8 hsa-miR-326 CCUCUGGGCCCUUCCUCCAG
mir-376c 402 409 1A，M8 HSA-MIR-376C aacauagaggaaauuccacg
mir-448 265 271 M8 hsa-miR-448 UUGCAUAUGUAGGAUGUCCCAU
miR-496 405 411 1a HSA-MIR-496 Auuacauggccaaucuc
miR-93.hd/291-3p/294/295/302/372/373/520 385 391 M8 HSA-MIR-93brain aaagugcuguucgugcagguag
hsa-miR-302a uaagugcuugcauguuuguga
hsa-miR-302b UAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302c uaagugcuuccauguucagugg
hsa-miR-302d Uaagugcuauguugugugu
HSA-MIR-372 AAAGUGCUGCGACAUUUGAGCGU
HSA-MIR-373 Gaagugcuucgauuuggggugu
HSA-MIR-520E Aaagugcuuuuuugaggg
hsa-miR-520a AAAGUGCUUCCCUUUGGACUGU
hsa-miR-520b aaagugcuuuuuuagaggg
hsa-miR-520c aaagugcuuuuuuaggggug
hsa-miR-520d aaaguguuugugggguggguu
mir-96 478 484 1a HSA-MIR-96brain uuuggcacuagcacauuuuugc