Gene Page:ZNF148

Summary?
GeneID 7707
Symbol ZNF148
Synonyms BERF-1|BFCOL1|HT-BETA|ZBP-89|ZFP148|pHZ-52
Description zinc finger protein 148
Reference MIM:601897|HGNC:HGNC:12933|Ensembl:ENSG00000163848|HPRD:03540|Vega:OTTHUMG00000159448
Gene type protein-coding
Map location 3q21
Pascal p-value 0.005
Sherlock p-value 0.501
eGene Meta

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
Expression Meta-analysis of gene expression Pvalue: 1.378

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section III. Gene Ontology annotation

Molecular function 去term Evidence Neuro keywords PubMed ID
GO:0003676 nucleic acid binding IEA -
GO:0003677 DNA binding IEA -
GO:0003704 specific RNA polymerase II transcription factor activity TAS 9685330
GO:0008270 zinc ion binding IEA -
GO:0016563 transcription activator activity TAS 8355710
GO:0046872 metal ion binding IEA -
Biological process 去term Evidence Neuro keywords PubMed ID
GO:0000122 negative regulation of transcription from RNA polymerase II promoter TAS 9685330
GO:0006355 regulation of transcription, DNA-dependent IEA -
GO:0006355 regulation of transcription, DNA-dependent TAS 8355710
GO:0006350 transcription IEA -
GO:0006968 cellular defense response TAS 8355710
Cellular component 去term Evidence Neuro keywords PubMed ID
GO:0005794 Golgi apparatus IDA 18029348
GO:0005622 intracellular IEA -
GO:0005634 nucleus IEA -
GO:0005634 nucleus TAS 8355710
GO:0005665 DNA-directed RNA polymerase II, core complex TAS 8355710
GO:0005730 nucleolus IDA 18029348

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
ONKEN UVEAL MELANOMA DN 526 357 All SZGR 2.0 genes in this pathway
THUM SYSTOLIC HEART FAILURE DN 244 147 All SZGR 2.0 genes in this pathway
WANG CLIM2 TARGETS UP 269 146 All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404 246 All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION UP 119 66 All SZGR 2.0 genes in this pathway
KIM WT1 TARGETS 12HR DN 209 122 All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE DN 485 334 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 1 DN 378 231 All SZGR 2.0 genes in this pathway
LINDGREN BLADDER CANCER CLUSTER 3 UP 329 196 All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 1781 1082 All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584 356 All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE AUGMENTED BY MYC 108 74 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 DN 855 609 All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 COMMON DN 483 336 All SZGR 2.0 genes in this pathway
MARTORIATI MDM4 TARGETS FETAL LIVER DN 514 319 All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584 395 All SZGR 2.0 genes in this pathway
MAGRANGEAS MULTIPLE MYELOMA IGG VS IGA DN 26 16 All SZGR 2.0 genes in this pathway
FLECHNER PBL KIDNEY TRANSPLANT REJECTED VS OK DN 51 35 All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT REJECTED VS OK DN 546 351 All SZGR 2.0 genes in this pathway
HADDAD T LYMPHOCYTE AND NK PROGENITOR UP 78 56 All SZGR 2.0 genes in this pathway
PARK HSC AND MULTIPOTENT PROGENITORS 50 33 All SZGR 2.0 genes in this pathway
MARIADASON RESPONSE TO BUTYRATE CURCUMIN SULINDAC TSA 8 16 7 All SZGR 2.0 genes in this pathway
RAMASWAMY METASTASIS DN 61 47 All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE UP 1691 1088 All SZGR 2.0 genes in this pathway
GERHOLD ADIPOGENESIS DN 64 44 All SZGR 2.0 genes in this pathway
WELCSH BRCA1 TARGETS UP 198 132 All SZGR 2.0 genes in this pathway
DAZARD RESPONSE TO UV NHEK DN 318 220 All SZGR 2.0 genes in this pathway
SESTO RESPONSE TO UV C5 46 36 All SZGR 2.0 genes in this pathway
JI RESPONSE TO FSH UP 74 56 All SZGR 2.0 genes in this pathway
RIGGINS TAMOXIFEN RESISTANCE DN 220 147 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 TARGETS UP 673 430 All SZGR 2.0 genes in this pathway
MARTINEZ TP53 TARGETS DN 593 372 All SZGR 2.0 genes in this pathway
MARTINEZ RB1 AND TP53 TARGETS DN 591 366 All SZGR 2.0 genes in this pathway
ACEVEDO LIVER TUMOR VS NORMAL ADJACENT TISSUE DN 274 165 All SZGR 2.0 genes in this pathway
ZHANG BREAST CANCER PROGENITORS UP 425 253 All SZGR 2.0 genes in this pathway
LEE DIFFERENTIATING T LYMPHOCYTE 200 115 All SZGR 2.0 genes in this pathway
ZHANG TLX TARGETS 36HR DN 185 116 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS UP 221 135 All SZGR 2.0 genes in this pathway
金所有障碍少突细胞数量CORR DN 36 19 All SZGR 2.0 genes in this pathway
LEE BMP2 TARGETS DN 882 538 All SZGR 2.0 genes in this pathway
FEVR CTNNB1 TARGETS DN 553 343 All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824 528 All SZGR 2.0 genes in this pathway
RAO BOUND BY SALL4 227 149 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-1/206 825 831 m8 hsa-miR-1 UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZ UGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613 AGGAAUGUUCCUUCUUUGCC
hsa-miR-1 UGGAAUGUAAAGAAGUAUGUA
hsa-miR-206SZ UGGAAUGUAAGGAAGUGUGUGG
hsa-miR-613 AGGAAUGUUCCUUCUUUGCC
miR-101 4406 4412 1A hsa-miR-101 UACAGUACUGUGAUAACUGAAG
miR-124.1 184 190 m8 hsa-miR-124a UUAAGGCACGCGGUGAAUGCCA
miR-124/506 184 190 1A hsa-miR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
miR-125/351 3311 3317 1A hsa-miR-125bbrain UCCCUGAGACCCUAACUUGUGA
hsa-miR-125abrain UCCCUGAGACCCUUUAACCUGUG
miR-128 2446 2452 1A hsa-miR-128a UCACAGUGAACCGGUCUCUUUU
hsa-miR-128b UCACAGUGAACCGGUCUCUUUC
miR-130/301 388 394 m8 hsa-miR-130abrain CAGUGCAAUGUUAAAAGGGCAU
hsa-miR-301 CAGUGCAAUAGUAUUGUCAAAGC
hsa-miR-130bbrain CAGUGCAAUGAUGAAAGGGCAU
hsa-miR-454-3p UAGUGCAAUAUUGCUUAUAGGGUUU
miR-136 72 78 m8 hsa-miR-136 ACUCCAUUUGUUUUGAUGAUGGA
miR-137 3802 3809 1A,m8 hsa-miR-137 UAUUGCUUAAGAAUACGCGUAG
miR-138 2203 2210 1A,m8 hsa-miR-138brain AGCUGGUGUUGUGAAUC
miR-139 816 822 1A hsa-miR-139brain UCUACAGUGCACGUGUCU
miR-140 505 511 m8 hsa-miR-140brain AGUGGUUUUACCCUAUGGUAG
miR-141/200a 4929 4935 1A hsa-miR-141 UAACACUGUCUGGUAAAGAUGG
hsa-miR-200a UAACACUGUCUGGUAACGAUGU
miR-142-5p 1316 1322 m8 hsa-miR-142-5p CAUAAAGUAGAAAGCACUAC
miR-143 1004 1010 m8 hsa-miR-143brain UGAGAUGAAGCACUGUAGCUCA
miR-144 4405 4412 1A,m8 hsa-miR-144 UACAGUAUAGAUGAUGUACUAG
hsa-miR-144 UACAGUAUAGAUGAUGUACUAG
hsa-miR-144 UACAGUAUAGAUGAUGUACUAG
miR-146 1727 1733 1A hsa-miR-146a UGAGAACUGAAUUCCAUGGGUU
hsa-miR-146bbrain UGAGAACUGAAUUCCAUAGGCU
miR-153 3492 3498 1A hsa-miR-153 UUGCAUAGUCACAAAAGUGA
miR-17-5p/20/93.mr/106/519.d 29 36 1A,m8 hsa-miR-17-5p CAAAGUGCUUACAGUGCAGGUAGU
hsa-miR-20abrain UAAAGUGCUUAUAGUGCAGGUAG
hsa-miR-106a AAAAGUGCUUACAGUGCAGGUAGC
hsa-miR-106bSZ UAAAGUGCUGACAGUGCAGAU
hsa-miR-20bSZ CAAAGUGCUCAUAGUGCAGGUAG
hsa-miR-519d CAAAGUGCCUCCCUUUAGAGUGU
miR-183 530 536 1A hsa-miR-183 UAUGGCACUGGUAGAAUUCACUG
miR-186 2328 2334 1A hsa-miR-186 CAAAGAAUUCUCCUUUUGGGCUU
hsa-miR-186 CAAAGAAUUCUCCUUUUGGGCUU
miR-196 4140 4146 1A hsa-miR-196a UAGGUAGUUUCAUGUUGUUGG
hsa-miR-196b UAGGUAGUUUCCUGUUGUUGG
miR-199 4575 4581 m8 hsa-miR-199a CCCAGUGUUCAGACUACCUGUUC
hsa-miR-199b CCCAGUGUUUAGACUAUCUGUUC
miR-200bc/429 5032 5039 1A,m8 hsa-miR-200b UAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200c UAAUACUGCCGGGUAAUGAUGG
hsa-miR-429 UAAUACUGUCUGGUAAAACCGU
miR-203.1 3858 3865 1A,m8 hsa-miR-203 UGAAAUGUUUAGGACCACUAG
hsa-miR-203 UGAAAUGUUUAGGACCACUAG
hsa-miR-203 UGAAAUGUUUAGGACCACUAG
hsa-miR-203 UGAAAUGUUUAGGACCACUAG
miR-204/211 1739 1746 1A,m8 hsa-miR-204brain UUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211 UUCCCUUUGUCAUCCUUCGCCU
miR-205 4100 4106 1A hsa-miR-205 UCCUUCAUUCCACCGGAGUCUG
miR-208 1356 1362 1A hsa-miR-208 AUAAGACGAGCAAAAAGCUUGU
miR-210 289 295 1A hsa-miR-210 CUGUGCGUGUGACAGCGGCUGA
miR-216 453 459 1A hsa-miR-216 UAAUCUCAGCUGGCAACUGUG
miR-219 3592 3599 1A,m8 hsa-miR-219brain UGAUUGUCCAAACGCAAUUCU
miR-221/222 4615 4621 1A hsa-miR-221brain AGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brain AGCUACAUCUGGCUACUGGGUCUC
miR-223 5750 5756 m8 hsa-miR-223 UGUCAGUUUGUCAAAUACCCC
miR-23 2221 2227 m8 hsa-miR-23abrain AUCACAUUGCCAGGGAUUUCC
hsa-miR-23bbrain AUCACAUUGCCAGGGAUUACC
miR-24 5684 5690 m8 hsa-miR-24SZ UGGCUCAGUUCAGCAGGAACAG
miR-25/32/92/363/367 3494 3500 1A hsa-miR-25brain CAUUGCACUUGUCUCGGUCUGA
hsa-miR-32 UAUUGCACAUUACUAAGUUGC
hsa-miR-92 UAUUGCACUUGUCCCGGCCUG
hsa-miR-367 AAUUGCACUUUAGCAAUGGUGA
hsa-miR-92bSZ UAUUGCACUCGUCCCGGCCUC
miR-26 3227 3234 1A,m8 hsa-miR-26abrain UUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZ UUCAAGUAAUUCAGGAUAGGUU
hsa-miR-26abrain UUCAAGUAAUCCAGGAUAGGC
hsa-miR-26bSZ UUCAAGUAAUUCAGGAUAGGUU
miR-27 2446 2453 1A,m8 hsa-miR-27abrain UUCACAGUGGCUAAGUUCCGC
hsa-miR-27bbrain UUCACAGUGGCUAAGUUCUGC
miR-30-5p 3960 3967 1A,m8 hsa-miR-30a-5p UGUAAACAUCCUCGACUGGAAG
hsa-miR-30cbrain UGUAAACAUCCUACACUCUCAGC
hsa-miR-30dSZ UGUAAACAUCCCCGACUGGAAG
hsa-miR-30bSZ UGUAAACAUCCUACACUCAGCU
hsa-miR-30e-5p UGUAAACAUCCUUGACUGGA
miR-320 1891 1897 m8 hsa-miR-320 AAAAGCUGGGUUGAGAGGGCGAA
miR-323 4528 4534 m8 hsa-miR-323brain GCACAUUACACGGUCGACCUCU
hsa-miR-323brain GCACAUUACACGGUCGACCUCU
miR-330 4533 4540 1A,m8 hsa-miR-330brain GCAAAGCACACGGCCUGCAGAGA
miR-346 2347 2353 m8 hsa-miR-346brain UGUCUGCCCGCAUGCCUGCCUCU
hsa-miR-346brain UGUCUGCCCGCAUGCCUGCCUCU
miR-34b 182 188 m8 hsa-miR-34b UAGGCAGUGUCAUUAGCUGAUUG
miR-361 601 607 m8 hsa-miR-361brain UUAUCAGAAUCUCCAGGGGUAC
hsa-miR-361brain UUAUCAGAAUCUCCAGGGGUAC
miR-365 1148 1154 m8 hsa-miR-365 UAAUGCCCCUAAAAAUCCUUAU
miR-370 396 402 m8 hsa-miR-370brain GCCUGCUGGGGUGGAACCUGG
miR-377 342 349 1A,m8 hsa-miR-377 AUCACACAAAGGCAACUUUUGU
miR-378 3841 3847 1A hsa-miR-378 CUCCUGACUCCAGGUCCUGUGU
miR-384 3389 3395 1A hsa-miR-384 AUUCCUAGAAAUUGUUCAUA
miR-410 4523 4529 1A hsa-miR-410 AAUAUAACACAGAUGGCCUGU
hsa-miR-410 AAUAUAACACAGAUGGCCUGU
miR-448 3492 3498 1A hsa-miR-448 UUGCAUAUGUAGGAUGUCCCAU
miR-493-5p 3741 3748 1A,m8 hsa-miR-493-5p UUGUACAUGGUAGGCUUUCAUU
miR-494 5711 5717 1A hsa-miR-494brain UGAAACAUACACGGGAAACCUCUU
miR-499 1356 1362 1A hsa-miR-499 UUAAGACUUGCAGUGAUGUUUAA
miR-539 948 955 1A,m8 hsa-miR-539 GGAGAAAUUAUCCUUGGUGUGU
hsa-miR-539 GGAGAAAUUAUCCUUGGUGUGU
miR-542-3p 4560 4566 m8 hsa-miR-542-3p UGUGACAGAUUGAUAACUGAAA
miR-543 1334 1340 m8 hsa-miR-543 AAACAUUCGCGGUGCACUUCU
miR-7 3615 3621 m8 hsa-miR-7SZ UGGAAGACUAGUGAUUUUGUUG
miR-93.hd/291-3p/294/295/302/372/373/520 920 927 1A,m8 hsa-miR-93brain AAAGUGCUGUUCGUGCAGGUAG
hsa-miR-302a UAAGUGCUUCCAUGUUUUGGUGA
hsa-miR-302b UAAGUGCUUCCAUGUUUUAGUAG
hsa-miR-302c UAAGUGCUUCCAUGUUUCAGUGG
hsa-miR-302d UAAGUGCUUCCAUGUUUGAGUGU
hsa-miR-372 AAAGUGCUGCGACAUUUGAGCGU
hsa-miR-373 GAAGUGCUUCGAUUUUGGGGUGU
hsa-miR-520e AAAGUGCUUCCUUUUUGAGGG
hsa-miR-520a AAAGUGCUUCCCUUUGGACUGU
hsa-miR-520b AAAGUGCUUCCUUUUAGAGGG
hsa-miR-520c AAAGUGCUUCCUUUUAGAGGGUU
hsa-miR-520d AAAGUGCUUCUCUUUGGUGGGUU