SZGR2 - Beplay体育中心

概括?

基因	7917
象征	BAG6
Synonyms	BAG-6\|BAT3\|D6S52E\|G3
Description	BCL2 associated athanogene 6
Reference	MIM：142590\|HGNC:HGNC:13919\|Ensembl:ENSG00000204463\|HPRD:00808\|Vega:OTTHUMG00000031171
Gene type	protein-coding
Map location	6p21.3
Pascal p-value	1E-12
Sherlock P值	1
eGene	Caudate basal ganglia Cerebellar Hemisphere Cerebellum 皮质额叶皮质BA9 迈尔斯的顺式和跨性别元

数据源中的基因

Gene set name	Method of gene set	Description	Info
CV:PGCnp	Genome-wide Association Study	GWAS

第一节遗传学和表观遗传学注释

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	pvalue	qvalue	TSS distance	EQTL类型
RS16836102	chr4	4716366	BAG6	7917		0.07		trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression of temporal and spatial changes (BrainSpan)

脚注：
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions

Section III. Gene Ontology annotation

分子功能	去的术语	Evidence	Neuro keywords	PubMed ID
GO:0005515	protein binding	新闻学会		14667819\|15231747\|17353931
生物过程	去的术语	Evidence	Neuro keywords	PubMed ID
去：0006464	蛋白质改性过程	IEA		-
Cellular component	去的术语	Evidence	Neuro keywords	PubMed ID
GO:0005634	nucleus	IEA		-

第四节。蛋白质蛋白相互作用注释

互动者	Aliases B	Official full name B	Experimental	资源	PubMed ID
ARPC3	ARC21 \| p21-Arc	actin related protein 2/3 complex, subunit 3, 21kDa	两个杂交	BioGRID	16169070
B2M	-	beta-2-microglobulin	两个杂交	BioGRID	16169070
C19orf10	EUROIMAGE1875335 \| IL25 \| IL27 \| IL27w \| R33729_1 \| SF20	chromosome 19 open reading frame 10	两个杂交	BioGRID	16169070
CDK4	CMM3 \| MGC14458 \| PSK-J3	cyclin-dependent kinase 4	两个杂交	BioGRID	16169070
CHN2	arhgap3 \|BCH \|MGC138360 \|RHOGAP3	Chimerin（Chimaerin）2	两个杂交	BioGRID	16169070
CSTF2	CstF-64	切割刺激因子，3'Pre-RNA，亚基2，64KDA	两个杂交	BioGRID	16169070
CTSB	APPS \| CPSB	cathepsin B	两个杂交	BioGRID	16169070
CTSE	CATE	cathepsin E	两个杂交	BioGRID	16169070
DNAJB11	ABBP-2 \|abbp2 \|DJ9 \|EDJ \|ERDJ3 \|ERJ3 \|hedj \|Pro1080 \|UNQ537 \|HDJ9	DNAJ（HSP40）同源物，亚家族B，成员11	两个杂交	BioGRID	16169070
DPT	TRAMP	dermatopontin	两个杂交	BioGRID	16169070
EDN1	ET1 \| HDLCQ7	endothelin 1	两个杂交	BioGRID	16169070
EFEMP2	FBLN4 \| MBP1 \| UPH1	含EGF的纤维蛋白样细胞外基质蛋白2	两个杂交	BioGRID	16189514
FAM173A	C16orf24 \|MGC2494	family with sequence similarity 173, member A	两个杂交	BioGRID	16169070
FKBP2	FKBP-13 \|PPIASE	FK506 binding protein 2, 13kDa	两个杂交	BioGRID	16169070
HSPA1A	FLJ54303 \| FLJ54370 \| FLJ54392 \| FLJ54408 \| FLJ75127 \| HSP70-1 \| HSP70-1A \| HSP70I \| HSP72 \| HSPA1 \| HSPA1B	热休克70KDA蛋白1A	in vivo	BioGRID	11230127
IER3	DIF-2 \| DIF2 \| GLY96 \| IEX-1 \| IEX-1L \| IEX1 \| PRG1	immediate early response 3	IEX-1的未指定同工型与BAT3相互作用。	BIND	15451437
IGFBP5	IBP5	胰岛素样生长因子结合蛋白5	两个杂交	BioGRID	16169070
IKBKAP	DKFZp781H1425 \| DYS \| ELP1 \| FD \| FLJ12497 \| IKAP \| IKI3 \| TOT1	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	两个杂交	BioGRID	16169070
immt	DKFZp779P1653 \| HMP \| MGC111146 \| P87 \| P87/89 \| P89 \| PIG4 \| PIG52	inner membrane protein, mitochondrial (mitofilin)	两个杂交	BioGRID	16169070
IQCG	DKFZP434B227 \|FLJ11667 \|FLJ23571 \|FLJ37775	IQ motif containing G	两个杂交	BioGRID	16169070
KLHL12	C3IP1 \|dkir \|FLJ27152	kelch-like 12 (Drosophila)	两个杂交	BioGRID	16189514
MAGED1	DLXIN-1 \| NRAGE	melanoma antigen family D, 1	亲和力捕获ms	BioGRID	17353931
NBL1	D1S1733E \| DAN \| DAND1 \| MGC8972 \| NB \| NO3	神经母细胞瘤，抑制肿瘤性1	-	HPRD,BioGRID	10390159
ndufa6	B14 \|CI-B14 \|lyrm6 \|NADHB14	NADH脱氢酶（泛氨基酮）1α子复合物，6，14KDA	两个杂交	BioGRID	16169070
NOMO1	Nomo \| PM5	NODAL modulator 1	两个杂交	BioGRID	16169070
PELP1	HMX3 \|mnar \|P160	proline, glutamate and leucine rich protein 1	两个杂交	BioGRID	16169070
PPAP2C	LPP2 \| PAP-2c \| PAP2-g	磷脂酸磷酸酶2C型	两个杂交	BioGRID	16169070
PPP4C	PP4 \| PPH3 \| PPX	protein phosphatase 4 (formerly X), catalytic subunit	亲和力捕获ms	BioGRID	17353931
PRG2	lppr3 \|LPR3 \|PRG-2	plasticity-related gene 2	两个杂交	BioGRID	16169070
PRNP	ASCR \| CD230 \| CJD \| GSS \| MGC26679 \| PRIP \| PrP \| PrP27-30 \| PrP33-35C \| PrPc \| prion	prion protein	两个杂交	BioGRID	16169070
PTH	PTH1	parathyroid hormone	两个杂交	BioGRID	16169070
RAB8A	MEL \| RAB8	RAB8A, member RAS oncogene family	两个杂交	BioGRID	16169070
RCN2	E6BP \| ERC-55 \| ERC55 \| TCBP49	reticulocalbin 2, EF-hand calcium binding domain	两个杂交	BioGRID	16169070
REG1B	PSPS2 \| REGH \| REGI-BETA \| REGL	regenerating islet-derived 1 beta	两个杂交	BioGRID	16169070
RNF126	FLJ20552 \| MGC1022 \| MGC14317	ring finger protein 126	-	HPRD	14667819
S100A4	18a2 \|42a \|capl \|FSP1 \|MTS1 \|p9ka \|Pel98	S100 calcium binding protein A4	两个杂交	BioGRID	16169070
SETDB1	eset \|kg1t \|KIAA0067 \|KMT1E	SET domain, bifurcated 1	两个杂交	BioGRID	16169070
SMN1	BCD541 \| SMA \| SMA1 \| SMA2 \| SMA3 \| SMA4 \| SMA@ \| SMN \| SMNT \| T-BCD541	survival of motor neuron 1, telomeric	两个杂交	BioGRID	16169070
STX5	SED5 \| STX5A	syntaxin 5	两个杂交	BioGRID	16169070
TAC1	Hs.2563 \| NK2 \| NKNA \| NPK \| TAC2	tachykinin, precursor 1	两个杂交	BioGRID	16169070
TDGF1	Cr \|CRGF \|Cripto \|Cripto-1	teratocarcinoma-derived growth factor 1	两个杂交	BioGRID	16169070
TOMM20	KIAA0016 \|MAS20 \|MGC117367 \|MOM19 \|TOM20	translocase of outer mitochondrial membrane 20 homolog (yeast)	两个杂交	BioGRID	16169070
TSC22D1	DKFZp686O19206 \| MGC17597 \| RP11-269C23.2 \| TGFB1I4 \| TSC22	TSC22 domain family, member 1	亲和力捕获ms	BioGRID	17353931
UBL7	BMSC-UbP \| MGC14421 \| TCBA1	ubiquitin-like 7 (bone marrow stromal cell-derived)	-	HPRD	14667819
WDR8	FLJ20430 \| MGC99569	WD repeat domain 8	亲和力捕获ms	BioGRID	17353931
XRN1	DKFZP434P0721 \|DKFZP686B22225 \|DKFZP686F19113 \|FLJ41903 \|Sep1	5'-3' exoribonuclease 1	-	HPRD,BioGRID	15231747

V.途径注释

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
Liu Sox4靶向DN	309	191	该途径中的所有SZGR 2.0基因
Ginestier乳腺癌20Q13扩增DN	180	101	该途径中的所有SZGR 2.0基因
DARWICHE SKIN TUMOR PROMOTER DN	185	115	该途径中的所有SZGR 2.0基因
DARWICHE PAPILLOMA RISK LOW DN	165	107	该途径中的所有SZGR 2.0基因
Darwiche Papilloma风险高DN	180	110	该途径中的所有SZGR 2.0基因
darwiche鳞状细胞癌DN	181	107	该途径中的所有SZGR 2.0基因
伊万诺夫在结肠癌中突变	13	9	该途径中的所有SZGR 2.0基因
RASHI RESPONSE TO IONIZING RADIATION 6	84	54	该途径中的所有SZGR 2.0基因
MARTORIATI MDM4 TARGETS FETAL LIVER DN	514	319	该途径中的所有SZGR 2.0基因
Benporath Nanog目标	988	594	该途径中的所有SZGR 2.0基因
MCCLUNG DELTA FOSB TARGETS 8WK	47	38	该途径中的所有SZGR 2.0基因
Lee Calorie限制性新皮层	83	66	该途径中的所有SZGR 2.0基因
BLALOCK ALZHEIMERS DISEASE DN	1237	837	该途径中的所有SZGR 2.0基因
BURTON ADIPOGENESIS 7	51	34	该途径中的所有SZGR 2.0基因
MARSON BOUND BY E2F4 UNSTIMULATED	728	415	该途径中的所有SZGR 2.0基因
MATZUK SPERMATOCYTE	72	55	该途径中的所有SZGR 2.0基因
MUELLER PLURINET	299	189	该途径中的所有SZGR 2.0基因
MOOTHA PGC	420	269	该途径中的所有SZGR 2.0基因
Yoshimura mapk8靶向	1305	895	该途径中的所有SZGR 2.0基因
FONTAINE FOLLICULAR THYROID ADENOMA UP	75	43	该途径中的所有SZGR 2.0基因
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR UP	756	494	该途径中的所有SZGR 2.0基因
KIM BIPOLAR DISORDER OLIGODENDROCYTE DENSITY CORR UP	682	440	该途径中的所有SZGR 2.0基因

Section VI. microRNA annotation

mirna家族	Target position			mirna id	miRNA seq
mirna家族	UTR start	UTR end	Match method	mirna id	miRNA seq
miR-200bc/429	60	66	m8	HSA-MIR-200B	UAAUACUGCCUGGUAAUGAUGAC
				HSA-MIR-200C	UAAUACUGCCGGGUAAUGAUGG
				HSA-MIR-429	UAAUACUGUCUGGUAAAACCGU
miR-331	31	37	1A	HSA-MIR-331^brain	GCCCCUGGGCCUAUCCUAGAA

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click这里查看与SZ相关的miRNA列表。
大脑：基于miRNA微阵列表达研究在大脑中表达的miRNA。点击这里to see the list of brain related miRNAs.

Gene Page:BAG6