Gene Page:DNAJB14

Summary?
GeneID 79982
Symbol DNAJB14
Synonyms EGNR9427|PRO34683
Description DnaJ heat shock protein family (Hsp40) member B14
Reference HGNC:HGNC:25881|Ensembl:ENSG00000164031|HPRD:07013|Vega:OTTHUMG00000131049
Gene type protein-coding
Map location 4q23
Pascal p-value 0.003
Sherlock p-value 0.563

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
Expression Meta-analysis of gene expression Pvalue: 2.358

Section I. Genetics and epigenetics annotation


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
POLR1B 0.95 0.96
VEZT 0.95 0.96
DHX57 0.95 0.97
TMEM57 0.95 0.96
ZNF512 0.95 0.96
ZNF527 0.94 0.93
DHX29 0.94 0.95
ZNF45 0.94 0.95
COPG2 0.94 0.95
ZNF280D 0.94 0.95
Top 10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.31 -0.79 -0.90
FXYD1 -0.79 -0.91
MT-CO2 -0.79 -0.91
HLA-F -0.79 -0.82
AF347015.27 -0.78 -0.88
TSC22D4 -0.78 -0.85
AF347015.33 -0.78 -0.88
S100B -0.77 -0.85
AIFM3 -0.77 -0.81
IFI27 -0.77 -0.88

Section III. Gene Ontology annotation

Molecular function 去的术语 Evidence Neuro keywords PubMed ID
GO:0031072 heat shock protein binding IEA -
GO:0051082 unfolded protein binding IEA -
Biological process 去的术语 Evidence Neuro keywords PubMed ID
GO:0006457 protein folding IEA -
Cellular component 去的术语 Evidence Neuro keywords PubMed ID
GO:0016020 membrane IEA -
GO:0016021 integral to membrane IEA -

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408 247 All SZGR 2.0 genes in this pathway
OSMAN BLADDER CANCER UP 404 246 All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER ZNF217 AMPLIFIED UP 78 48 All SZGR 2.0 genes in this pathway
GINESTIER BREAST CANCER 20Q13 AMPLIFICATION UP 119 66 All SZGR 2.0 genes in this pathway
SENESE HDAC1 TARGETS UP 457 269 All SZGR 2.0 genes in this pathway
SENESE HDAC1 AND HDAC2 TARGETS UP 238 144 All SZGR 2.0 genes in this pathway
SENESE HDAC2目标了 114 66 All SZGR 2.0 genes in this pathway
SENESE HDAC3 TARGETS UP 501 327 All SZGR 2.0 genes in this pathway
BUYTAERT PHOTODYNAMIC THERAPY STRESS UP 811 508 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
HADDAD B LYMPHOCYTE PROGENITOR 293 193 All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI DN 172 107 All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022 619 All SZGR 2.0 genes in this pathway
MARSON BOUND BY E2F4 UNSTIMULATED 728 415 All SZGR 2.0 genes in this pathway
YOSHIMURA MAPK8 TARGETS UP 1305 895 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS OLIGODENDROCYTE NUMBER CORR DN 36 19 All SZGR 2.0 genes in this pathway
KIM ALL DISORDERS DURATION CORR UP 9 7 All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 1 DN 63 39 All SZGR 2.0 genes in this pathway
GOBERT OLIGODENDROCYTE DIFFERENTIATION DN 1080 713 All SZGR 2.0 genes in this pathway
ACEVEDO FGFR1 TARGETS IN PROSTATE CANCER MODEL DN 308 187 All SZGR 2.0 genes in this pathway

Section VI. microRNA annotation

miRNA family Target position miRNA ID miRNA seq
UTR start UTR end Match method
miR-124/506 976 982 m8 hsa-miR-506 UAAGGCACCCUUCUGAGUAGA
hsa-miR-124brain UAAGGCACGCGGUGAAUGCC
miR-132/212 133 139 m8 hsa-miR-212SZ UAACAGUCUCCAGUCACGGCC
hsa-miR-132brain UAACAGUCUACAGCCAUGGUCG
miR-30-3p 168 175 1A,m8 hsa-miR-30a-3p CUUUCAGUCGGAUGUUUGCAGC
hsa-miR-30e-3p CUUUCAGUCGGAUGUUUACAGC
miR-496 319 326 1A,m8 hsa-miR-496 AUUACAUGGCCAAUCUC
miR-505 1452 1458 1A hsa-miR-505 GUCAACACUUGCUGGUUUCCUC