Gene Page:MED28
Summary?
| GeneID | 80306 |
| Symbol | MED28 |
| Synonyms | 1500003D12Rik|EG1|magicin |
| Description | mediator complex subunit 28 |
| Reference | MIM:610311|HGNC:HGNC:24628|HPRD:14381| |
| Gene type | protein-coding |
| Map location | 4p16 |
| Pascal p-value | 0.005 |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section IV. Protein-protein interaction annotation
| Interactors | Aliases B | Official full name B | Experimental | Source | PubMed ID |
|---|---|---|---|---|---|
| CCNC | CycC | cyclin C | Affinity Capture-MS | BioGRID | 15175163 |
| CDC2L6 | CDK11 | KIAA1028 | bA346C16.3 | cell division cycle 2-like 6 (CDK8-like) | Affinity Capture-MS | BioGRID | 15175163 |
| CDK8 | K35 | MGC126074 | MGC126075 | cyclin-dependent kinase 8 | Affinity Capture-MS | BioGRID | 15175163 |
| GRB2 | ASH | EGFRBP-GRB2 | Grb3-3 | MST084 | MSTP084 | growth factor receptor-bound protein 2 | - | HPRD,BioGRID | 15467741 |
| KLHL12 | C3IP1 | DKIR | FLJ27152 | kelch-like 12 (Drosophila) | Two-hybrid | BioGRID | 16189514 |
| MAGEA11 | MAGE-11 | MAGE11 | MAGEA-11 | MGC10511 | melanoma antigen family A, 11 | Two-hybrid | BioGRID | 16189514 |
| MED1 | CRSP1 | CRSP200 | DRIP205 | DRIP230 | MGC71488 | PBP | PPARBP | PPARGBP | RB18A | TRAP220 | TRIP2 | mediator complex subunit 1 | Affinity Capture-MS | BioGRID | 15175163 |
| MED10 | L6 | MGC5309 | NUT2 | TRG20 | mediator complex subunit 10 | Affinity Capture-MS | BioGRID | 15175163 |
| MED11 | HSPC296 | MGC88387 | mediator complex subunit 11 | Affinity Capture-MS | BioGRID | 15175163 |
| MED12 | CAGH45 | HOPA | KIAA0192 | OPA1 | TNRC11 | TRAP230 | mediator complex subunit 12 | Affinity Capture-MS | BioGRID | 15175163 |
| MED13 | ARC250 | DRIP250 | HSPC221 | KIAA0593 | THRAP1 | TRAP240 | mediator complex subunit 13 | Affinity Capture-MS | BioGRID | 15175163 |
| MED13L | DKFZp781D0112 | FLJ21627 | KIAA1025 | PROSIT240 | THRAP2 | TRAP240L | mediator complex subunit 13-like | Affinity Capture-MS | BioGRID | 15175163 |
| MED14 | CRSP150 | CRSP2 | CSRP | CXorf4 | DRIP150 | EXLM1 | MGC104513 | RGR1 | TRAP170 | mediator complex subunit 14 | Affinity Capture-MS | BioGRID | 15175163 |
| MED15 | ARC105 | CAG7A | CTG7A | DKFZp686A2214 | DKFZp762B1216 | FLJ42282 | FLJ42935 | PCQAP | TIG-1 | TIG1 | TNRC7 | mediator complex subunit 15 | Affinity Capture-MS | BioGRID | 15175163 |
| MED16 | DRIP92 | THRAP5 | TRAP95 | mediator complex subunit 16 | Affinity Capture-MS | BioGRID | 15175163 |
| MED17 | CRSP6 | CRSP77 | DRIP80 | FLJ10812 | TRAP80 | mediator complex subunit 17 | Affinity Capture-MS | BioGRID | 15175163 |
| MED18 | FLJ20045 | p28b | mediator complex subunit 18 | Affinity Capture-MS | BioGRID | 15175163 |
| MED19 | DT2P1G7 | LCMR1 | mediator complex subunit 19 | - | HPRD,BioGRID | 15175163 |
| MED20 | DKFZp586D2223 | MGC29869 | PRO0213 | TRFP | mediator complex subunit 20 | Affinity Capture-MS | BioGRID | 15175163 |
| MED21 | SRB7 | SURB7 | mediator complex subunit 21 | Affinity Capture-MS | BioGRID | 15175163 |
| MED22 | MED24 | MGC48682 | SURF5 | mediator complex subunit 22 | Affinity Capture-MS | BioGRID | 15175163 |
| MED23 | CRSP130 | CRSP133 | CRSP3 | DKFZp434H0117 | DRIP130 | SUR2 | mediator complex subunit 23 | Affinity Capture-MS | BioGRID | 15175163 |
| MED24 | ARC100 | CRSP100 | CRSP4 | DRIP100 | KIAA0130 | MGC8748 | THRAP4 | TRAP100 | mediator complex subunit 24 | Affinity Capture-MS | BioGRID | 15175163 |
| MED25 | ACID1 | ARC92 | DKFZp434K0512 | MGC70671 |只有| PTOV2 | TCBAP0758 | mediator complex subunit 25 | Affinity Capture-MS | BioGRID | 15175163 |
| MED26 | CRSP7 | CRSP70 | mediator complex subunit 26 | - | HPRD,BioGRID | 15175163 |
| MED27 | CRAP34 | CRSP34 | CRSP8 | MGC11274 | TRAP37 | mediator complex subunit 27 | Affinity Capture-MS | BioGRID | 15175163 |
| MED28 | 1500003D12Rik | DKFZp434N185 | EG1 | magicin | mediator complex subunit 28 | Affinity Capture-MS | BioGRID | 15175163 |
| MED29 | DKFZp434H247 | IXL | mediator complex subunit 29 | Affinity Capture-MS | BioGRID | 15175163 |
| MED30 | MGC9890 | THRAP6 | TRAP25 | mediator complex subunit 30 | Affinity Capture-MS | BioGRID | 15175163 |
| MED30 | MGC9890 | THRAP6 | TRAP25 | mediator complex subunit 30 | - | HPRD | 11591653 |
| MED31 | 3110004H13Rik | CGI-125 | FLJ27436 | FLJ36714 | Soh1 | mediator complex subunit 31 | Affinity Capture-MS | BioGRID | 15175163 |
| MED4 | DRIP36 | FLJ10956 | HSPC126 | RP11-90M2.2 | TRAP36 | VDRIP | mediator complex subunit 4 | Affinity Capture-MS | BioGRID | 15175163 |
| MED6 | NY-REN-28 | mediator complex subunit 6 | Affinity Capture-MS | BioGRID | 15175163 |
| MED7 | CRSP33 | CRSP9 | MGC12284 | mediator complex subunit 7 | Affinity Capture-MS | BioGRID | 15175163 |
| MED8 | ARC32 | MGC17544 | MGC19641 | mediator complex subunit 8 | Affinity Capture-MS | BioGRID | 15175163 |
| MED9 | FLJ10193 | MED25 | MGC138234 | mediator complex subunit 9 | - | HPRD,BioGRID | 15175163 |
| NF2 | ACN | BANF | SCH | neurofibromin 2 (merlin) | Affinity Capture-Western Two-hybrid |
BioGRID | 15467741 |
| NF2 | ACN | BANF | SCH | neurofibromin 2 (merlin) | - | HPRD | 15175163 |
| POLR2A | MGC75453 | POLR2 | POLRA | RPB1 | RPBh1 | RPO2 | RPOL2 | RpIILS | hRPB220 | hsRPB1 | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2B | POL2RB | RPB2 | hRPB140 | hsRPB2 | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2C | RPB3 | RPB31 | hRPB33 | hsRPB3 | polymerase (RNA) II (DNA directed) polypeptide C, 33kDa | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2D | HSRBP4 | HSRPB4 | RBP4 | polymerase (RNA) II (DNA directed) polypeptide D | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2G | MGC138367 | MGC138369 | RPB7 | hRPB19 | hsRPB7 | polymerase (RNA) II (DNA directed) polypeptide G | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2J | MGC71910 | POLR2J1 | RPB11 | RPB11A | RPB11m | hRPB14 | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | Affinity Capture-MS | BioGRID | 15175163 |
| POLR2L | RBP10 | RPABC5 | RPB10 | RPB10beta | RPB7.6 | hRPB7.6 | hsRPB10b | DNA聚合酶(RNA) II(导演)多肽L,7.6kDa | Affinity Capture-MS | BioGRID | 15175163 |
| USHBP1 | AIEBP | FLJ38709 | FLJ90681 | MCC2 | Usher syndrome 1C binding protein 1 | Two-hybrid | BioGRID | 16189514 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| NAKAMURA TUMOR ZONE PERIPHERAL VS CENTRAL DN | 634 | 384 | All SZGR 2.0 genes in this pathway |
| CHARAFE BREAST CANCER LUMINAL VS MESENCHYMAL UP | 450 | 256 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO ANDROGEN UP | 29 | 21 | All SZGR 2.0 genes in this pathway |
| WANG RESPONSE TO FORSKOLIN UP | 23 | 17 | All SZGR 2.0 genes in this pathway |
| DODD NASOPHARYNGEAL CARCINOMA DN | 1375 | 806 | All SZGR 2.0 genes in this pathway |
| LINDGREN BLADDER CANCER CLUSTER 3 DN | 229 | 142 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP | 552 | 347 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY DOXORUBICIN UP | 1142 | 669 | All SZGR 2.0 genes in this pathway |
| LASTOWSKA NEUROBLASTOMA COPY NUMBER DN | 800 | 473 | All SZGR 2.0 genes in this pathway |
| STARK PREFRONTAL CORTEX 22Q11 DELETION DN | 517 | 309 | All SZGR 2.0 genes in this pathway |
| WANG SMARCE1 TARGETS DN | 371 | 218 | All SZGR 2.0 genes in this pathway |
| TOYOTA TARGETS OF MIR34B AND MIR34C | 463 | 262 | All SZGR 2.0 genes in this pathway |
| YOSHIOKA LIVER CANCER EARLY RECURRENCE DN | 65 | 31 | All SZGR 2.0 genes in this pathway |
| LINSLEY MIR16 TARGETS | 206 | 127 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN PREDNISOLONE RESISTANCE B ALL UP | 22 | 16 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN DAUNORUBICIN B ALL DN | 12 | 10 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN PREDNISOLONE RESISTANCE ALL UP | 19 | 15 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN DAUNORUBICIN ALL DN | 8 | 6 | All SZGR 2.0 genes in this pathway |
| HOLLEMAN ASPARAGINASE RESISTANCE ALL DN | 25 | 14 | All SZGR 2.0 genes in this pathway |
| ZWANG EGF INTERVAL DN | 214 | 124 | All SZGR 2.0 genes in this pathway |