Gene Page:CALM2

Summary？
基因 805
象征 CALM2
Synonyms camii | lqt15 | phkd | phkd2 | cam
Description 钙调蛋白2（磷酸化酶激酶，三角洲）
Reference MIM:114182|HGNC：HGNC：1445|ENSEMBL：ENSG00000143933|HPRD:00242|Vega：Otthumg00000128850
基因类型 蛋白质编码
Map location 2P21
Pascal p-value 0.008
Sherlock p-value 0.798
Support 细胞内信号转导
5-羟色胺

Gene in Data Sources
基因集名称 Method of gene set Description 信息
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation


第二节。转录组注释

一般基因表达（GTEX）

Not available

时间变化的基因表达（brainspan）

Footnote:
SC：亚皮质区域；SM：感觉运动区域；FC：额叶皮层；和TP：颞顶皮层
ST1：胎儿（13-26个概念后周），ST2：婴儿早期至童年（4个月至11年）和ST3：青春期至成年期（13-23年）
所示的栏表示表达分布的较低25％和上层25％。

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

互动者 别名b 官方全名b 实验 Source PubMed ID
AKAP9 AKAP350 |AKAP450 |cg-nap |Hyperion |KIAA0803 |MU-RMS-40.16A |prka9 |Yotiao 激酶（PRKA）锚蛋白（Yotiao）9 Two-hybrid Biogrid 12221128
ASCL2 Ash2 |哈希2 |mash2 |BHLHA45 Achaete-Scute复合物同源2（果蝇） - HPRD 10757985
CALD1 CDM |H-CAD |l-cad |MGC21352 |NAG22 caldesmon 1 - HPRD 11736632
ESR1 DKFZp686N23123 | ER | ESR | ESRA | Era | NR3A1 estrogen receptor 1 - HPRD 11981030
ESR2 er-beta |ESR-Beta |ESRB |estrb |ERB |NR3A2 雌激素受体2（ERβ） - HPRD 11981030
GRM5 gprc1e |mglur5 |mglur5a |mglur5b |mglu5 glutamate receptor, metabotropic 5 - HPRD 9242710|11953448
GRM7 FLJ40498 | GLUR7 | GPRC1G | MGLUR7 | mGlu7 glutamate receptor, metabotropic 7 - HPRD 11953448
INVS Inv |KIAA0573 |MGC133080 |MGC133081 |nph2 |NPHP2 inversin INVS的未指定同工型与Calm2相互作用2。 绑定 15723066
IQCB1 NPHP5 | PIQ | SLSN5 含有B1的智商主题 IQCB1与Calm2相互作用2。 绑定 15723066
KCNQ2 BFNC |EBN |EBN1 |enb1 |HNSPC |KCNA11 |KV7.2 |Kvebn1 钾电压门控通道，类似KQT的亚家族，成员2 - HPRD,BioGRID 12032157
KCNQ5 Kv7.5 钾电压门控通道，类似KQT的亚家族，成员5 - HPRD 12032157
KIAA1683 MGC131731 KIAA1683 Two-hybrid Biogrid 16189514
马克克斯 80K-L | FLJ14368 | FLJ90045 | MACS | MRACKS | PKCSL | PRKCSL 肉豆蔻酰化富含丙氨酸的蛋白激酶C底物 - HPRD,BioGRID 12577052
MRPL20 L20MT |MGC4779 |MGC74465 |MRP-L20 线粒体核糖体蛋白L20 Two-hybrid Biogrid 16169070
MYF5 BHLHC2 f肌原性的actor 5 - HPRD 10757985
MYF6 MRF4 | bHLHc4 肌原因子6（巨蛋白） - HPRD 10757985
myo6 DFNA22 |DFNB37 |KIAA0389 肌球蛋白VI Two-hybrid Biogrid 16169070
MYOD1 MYF3 | MYOD | PUM | bHLHc1 myogenic differentiation 1 - HPRD 10757985
myog myf4 |肌蛋白|BHLHC3 肌原（肌原因子4） - HPRD 10757985
Neurod1 BETA2 | BHF-1 | NEUROD | bHLHa3 neurogenic differentiation 1 - HPRD 10757985
PCNT KEN | MOPD2 | PCN | PCNT2 | PCNTB | PCTN2 | SCKL4 包中心 - HPRD 10823944|12221128
PPEF1 pp7 |PPEF |PPP7C protein phosphatase, EF-hand calcium binding domain 1 - HPRD 12051765
PPEF2 - protein phosphatase, EF-hand calcium binding domain 2 - HPRD 12051765
Rab3b - Rab3b, member RAS oncogene family - HPRD 11741295
TCF4 E2-2 |itf2 |MGC149723 |MGC149724 |pths |sef2 |sef2-1 |SEF2-1A |sef2-1b |BHLHB19 转录因子4 - HPRD 10757985


Section V. Pathway annotation

路径名 路径大小 # SZGR 2.0 genes in pathway 信息
kegg钙信号通路 178 134 All SZGR 2.0 genes in this pathway
KEGG磷脂酰肌醇信号传导系统 76 56 All SZGR 2.0 genes in this pathway
Kegg卵母细胞减数分裂 114 79 All SZGR 2.0 genes in this pathway
KEGG VASCULAR SMOOTH MUSCLE CONTRACTION 115 81 All SZGR 2.0 genes in this pathway
KEGG LONG TERM POTENTIATION 70 57 All SZGR 2.0 genes in this pathway
KEGG生成信号通路 126 103 All SZGR 2.0 genes in this pathway
kegg嗅觉转导 389 85 All SZGR 2.0 genes in this pathway
KEGG INSULIN SIGNALING PATHWAY 137 103 All SZGR 2.0 genes in this pathway
kegg gnRH信号通路 101 77 All SZGR 2.0 genes in this pathway
KEGG MELANOGENESIS 102 80 All SZGR 2.0 genes in this pathway
KEGG ALZHEIMERS DISEASE 169 110 All SZGR 2.0 genes in this pathway
Kegg神经胶质瘤 65 56 All SZGR 2.0 genes in this pathway
Biocarta No1途径 33 24 All SZGR 2.0 genes in this pathway
BIOCARTA AT1R PATHWAY 36 28 All SZGR 2.0 genes in this pathway
Biocarta BCR途径 37 28 All SZGR 2.0 genes in this pathway
生物卡丁生物肽途径 45 35 All SZGR 2.0 genes in this pathway
Biocarta Cacam途径 16 11 All SZGR 2.0 genes in this pathway
BIOCARTA HDAC PATHWAY 32 25 All SZGR 2.0 genes in this pathway
BIOCARTA GCR PATHWAY 22 17 All SZGR 2.0 genes in this pathway
生物钙化蛋白途径 21 17 All SZGR 2.0 genes in this pathway
BIOCARTA NDKDYNAMIN PATHWAY 21 15 All SZGR 2.0 genes in this pathway
BIOCARTA FCER1 PATHWAY 41 30 All SZGR 2.0 genes in this pathway
BIOCARTA FMLP PATHWAY 39 29 All SZGR 2.0 genes in this pathway
Biocarta Pyk2途径 31 24 All SZGR 2.0 genes in this pathway
Biocarta VIP途径 29 26 All SZGR 2.0 genes in this pathway
BIOCARTA NFAT PATHWAY 56 45 All SZGR 2.0 genes in this pathway
BIOCARTA NOS1 PATHWAY 24 21 All SZGR 2.0 genes in this pathway
BIOCARTA CCR5 PATHWAY 20 16 All SZGR 2.0 genes in this pathway
Biocarta PGC1A途径 26 20 All SZGR 2.0 genes in this pathway
Biocarta MEF2D途径 23 16 All SZGR 2.0 genes in this pathway
Biocarta GPCR途径 37 31 All SZGR 2.0 genes in this pathway
BIOCARTA TCR PATHWAY 49 37 All SZGR 2.0 genes in this pathway
REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS 18 10 All SZGR 2.0 genes in this pathway
REACTOME SIGNALLING BY NGF 217 167 All SZGR 2.0 genes in this pathway
REACTOME DAG AND IP3 SIGNALING 32 25 All SZGR 2.0 genes in this pathway
Reactome四氢无菌蛋白BH4合成回收的挽救和调节 13 9 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY ERBB2 101 78 All SZGR 2.0 genes in this pathway
EGFR在癌症中的反应组信号传导 109 80 All SZGR 2.0 genes in this pathway
Reactome抗原激活B细胞受体，导致第二使者产生 29 24 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY THE B CELL RECEPTOR BCR 126 90 All SZGR 2.0 genes in this pathway
Reactome NGF信号通过TRKA从质膜发出 137 105 All SZGR 2.0 genes in this pathway
FGFR的Reactome信号传导IN DISEASE 127 88 All SZGR 2.0 genes in this pathway
Reactome Enos激活和调节 20 14 All SZGR 2.0 genes in this pathway
REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 89 56 All SZGR 2.0 genes in this pathway
REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES 186 155 All SZGR 2.0 genes in this pathway
REACTOME NEURONAL SYSTEM 279 221 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY GPCR 920 449 All SZGR 2.0 genes in this pathway
Reactome阿片类药物信号传导 78 56 All SZGR 2.0 genes in this pathway
REACTOME CA DEPENDENT EVENTS 30 23 All SZGR 2.0 genes in this pathway
Reactome darpp 32事件 25 20 All SZGR 2.0 genes in this pathway
反应组神经递质受体结合和突触后细胞中的下游传播 137 110 All SZGR 2.0 genes in this pathway
REACTOME PLC BETA MEDIATED EVENTS 43 32 All SZGR 2.0 genes in this pathway
REACTOME SIGNALING BY PDGF 122 93 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNAL TRANSDUCTION 95 76 All SZGR 2.0 genes in this pathway
REACTOME MUSCLE CONTRACTION 48 24 All SZGR 2.0 genes in this pathway
Reactome RAS激活UOPN CA2通过NMDA受体Infux 17 15 All SZGR 2.0 genes in this pathway
REACTOME SMOOTH MUSCLE CONTRACTION 25 14 All SZGR 2.0 genes in this pathway
NMDA受体在谷氨酸结合和突触后事件上的反应组激活 37 32 All SZGR 2.0 genes in this pathway
REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS 27 23 All SZGR 2.0 genes in this pathway
反应组后NMDA受体激活事件 33 28 All SZGR 2.0 genes in this pathway
Reactome Creb通过CAMKII的激活来磷酸化 15 14 All SZGR 2.0 genes in this pathway
REACTOME DOWNSTREAM SIGNALING OF ACTIVATED FGFR 100 74 All SZGR 2.0 genes in this pathway
Reactome磷脂酶C介导的级联 54 40 All SZGR 2.0 genes in this pathway
谷氨酸结合上海藻酸盐受体的反应组激活 31 23 All SZGR 2.0 genes in this pathway
海藻酸盐受体的反应组离子型活性 11 11 All SZGR 2.0 genes in this pathway
碳水化合物的反应组代谢 247 154 All SZGR 2.0 genes in this pathway
反应组止血 466 331 All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM 933 616 All SZGR 2.0 genes in this pathway
反应组葡萄糖代谢 69 42 All SZGR 2.0 genes in this pathway
Reactome适应性免疫系统 539 350 All SZGR 2.0 genes in this pathway
Reactome血小板激活信号传导和聚集 208 138 All SZGR 2.0 genes in this pathway
FGFR的Reactome信号传导 112 80 All SZGR 2.0 genes in this pathway
Landis Erbb2乳腺肿瘤324向上 150 93 All SZGR 2.0 genes in this pathway
Baris甲状腺癌DN 59 45 All SZGR 2.0 genes in this pathway
Darwiche皮肤肿瘤启动子DN 185 115 All SZGR 2.0 genes in this pathway
Darwiche Papilloma风险低DN 165 107 All SZGR 2.0 genes in this pathway
DARWICHE PAPILLOMA RISK HIGH DN 180 110 All SZGR 2.0 genes in this pathway
DARWICHE SQUAMOUS CELL CARCINOMA DN 181 107 All SZGR 2.0 genes in this pathway
SCHLOSSER SERUM RESPONSE DN 712 443 All SZGR 2.0 genes in this pathway
带有E盒的WEI MYCN目标 795 478 All SZGR 2.0 genes in this pathway
gotzmann上皮到间充质过渡dn 206 136 All SZGR 2.0 genes in this pathway
BENPORATH NANOG TARGETS 988 594 All SZGR 2.0 genes in this pathway
Benporath SOX2目标 734 436 All SZGR 2.0 genes in this pathway
Benporath Myc Max目标 775 494 All SZGR 2.0 genes in this pathway
Mori大型BII淋巴细胞向上 86 49 All SZGR 2.0 genes in this pathway
Mori未成熟B淋巴细胞DN 90 55 All SZGR 2.0 genes in this pathway
Mori浆细胞DN 33 20 All SZGR 2.0 genes in this pathway
THEILGAARD NEUTROPHIL AT SKIN WOUND DN 225 163 All SZGR 2.0 genes in this pathway
Iglesias E2F目标 151 103 All SZGR 2.0 genes in this pathway
MUNSHI MULTIPLE MYELOMA UP 81 52 All SZGR 2.0 genes in this pathway
卫生部对干扰素beta的反应 71 49 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
MA垂体胎儿与成人DN 19 17 All SZGR 2.0 genes in this pathway
WELCSH BRCA1 TARGETS UP 198 132 All SZGR 2.0 genes in this pathway
Hedenfalk乳腺癌BRCA1与BRCA2 163 113 All SZGR 2.0 genes in this pathway
贝尔德糖尿病性肾病DN 434 302 All SZGR 2.0 genes in this pathway
江口大脑皮层DN 54 43 All SZGR 2.0 genes in this pathway
Bild HRAS致癌特征 261 166 All SZGR 2.0 genes in this pathway
Lein神经元标记 69 45 All SZGR 2.0 genes in this pathway
ZHANG BREAST CANCER PROGENITORS UP 425 253 All SZGR 2.0 genes in this pathway
马洛尼对17AAG DN的回应 79 45 All SZGR 2.0 genes in this pathway
LEE LIVER CANCER SURVIVAL DN 175 103 All SZGR 2.0 genes in this pathway
Ruiz TNC靶向DN 142 79 All SZGR 2.0 genes in this pathway
霍夫曼大到小淋巴细胞向上 163 102 All SZGR 2.0 genes in this pathway
Hsiao家政基因 389 245 All SZGR 2.0 genes in this pathway
FOURNIER ACINAR DEVELOPMENT LATE 2 277 172 All SZGR 2.0 genes in this pathway
由MYC约束 1103 714 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE S 162 86 All SZGR 2.0 genes in this pathway
马滕斯三维诺蛋白响应DN 841 431 All SZGR 2.0 genes in this pathway
Kim所有疾病Calb1 Corr Up 548 370 All SZGR 2.0 genes in this pathway
VERHAAK GLIOBLASTOMA NEURAL 129 85 All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS DN 1972 1213 All SZGR 2.0 genes in this pathway
棕熊UVC响应迟到 1137 655 All SZGR 2.0 genes in this pathway
Smad2或Smad3的Koinuma目标 824 528 All SZGR 2.0 genes in this pathway