Gene Page:DPF3
Summary?
| GeneID | 8110 |
| Symbol | DPF3 |
| Synonyms | BAF45C|CERD4 |
| Description | double PHD fingers 3 |
| Reference | MIM:601672|HGNC:HGNC:17427|Ensembl:ENSG00000205683|HPRD:03395|Vega:OTTHUMG00000171364 |
| Gene type | protein-coding |
| Map location | 14q24.2 |
| Pascal p-value | 0.006 |
| Sherlock p-value | 0.632 |
| eGene | Myers' cis & trans |
Gene in Data Sources
| Gene set name | Method of gene set | Description | Info |
|---|---|---|---|
| CV:PGCnp | Genome-wide Association Study | GWAS |
Section I. Genetics and epigenetics annotation
eQTL annotation
eQTL annotation| SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
|---|---|---|---|---|---|---|---|---|
| rs6687849 | chr1 | 175904808 | DPF3 | 8110 | 0.06 | trans | ||
| rs2481653 | chr1 | 176044120 | DPF3 | 8110 | 0.07 | trans | ||
| rs2502827 | chr1 | 176044216 | DPF3 | 8110 | 0 | trans | ||
| rs12405921 | chr1 | 206695730 | DPF3 | 8110 | 0.15 | trans | ||
| rs17572651 | chr1 | 218943612 | DPF3 | 8110 | 0.03 | trans | ||
| rs16829545 | chr2 | 151977407 | DPF3 | 8110 | 9.864E-12 | trans | ||
| rs3845734 | chr2 | 171125572 | DPF3 | 8110 | 8.59E-6 | trans | ||
| rs1967327 | chr2 | 179314358 | DPF3 | 8110 | 0.1 | trans | ||
| rs7584986 | chr2 | 184111432 | DPF3 | 8110 | 2.175E-9 | trans | ||
| rs2183142 | chr4 | 159232695 | DPF3 | 8110 | 0.06 | trans | ||
| rs17762315 | chr5 | 76807576 | DPF3 | 8110 | 4.888E-4 | trans | ||
| rs1368303 | chr5 | 147672388 | DPF3 | 8110 | 0.1 | trans | ||
| rs2530313 | chr7 | 148112233 | DPF3 | 8110 | 0.09 | trans | ||
| rs3118341 | chr9 | 25185518 | DPF3 | 8110 | 0.03 | trans | ||
| rs11139334 | chr9 | 84209393 | DPF3 | 8110 | 0.02 | trans | ||
| rs2393316 | chr10 | 59333070 | DPF3 | 8110 | 0.13 | trans | ||
| rs11846721 | chr14 | 63903555 | DPF3 | 8110 | 0.15 | trans | ||
| rs17104720 | chr14 | 77127308 | DPF3 | 8110 | 0.11 | trans | ||
| rs16955618 | chr15 | 29937543 | DPF3 | 8110 | 2.374E-27 | trans | ||
| rs3743068 | chr15 | 79047284 | DPF3 | 8110 | 0.16 | trans | ||
| rs17202303 | chr16 | 63131959 | DPF3 | 8110 | 0.13 | trans | ||
| rs1041786 | chr21 | 22617710 | DPF3 | 8110 | 0.01 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
Top co-expressed genes in brain regions
| Top 10 positively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| XRCC5 | 0.97 | 0.97 |
| KLHL7 | 0.97 | 0.96 |
| MCPH1 | 0.97 | 0.96 |
| MATR3 | 0.97 | 0.97 |
| SRP72 | 0.97 | 0.96 |
| CCT6A | 0.97 | 0.96 |
| NOL11 | 0.97 | 0.96 |
| WDR3 | 0.96 | 0.97 |
| POLR2B | 0.96 | 0.96 |
| INTS7 | 0.96 | 0.95 |
| Top 10 negatively co-expressed genes | ||
| Gene | Pearson's Correlation | Spearman's Correlation |
| AF347015.31 | -0.75 | -0.90 |
| MT-CO2 | -0.74 | -0.92 |
| AF347015.33 | -0.74 | -0.90 |
| HLA-F | -0.74 | -0.83 |
| FXYD1 | -0.73 | -0.91 |
| AF347015.27 | -0.73 | -0.89 |
| AIFM3 | -0.72 | -0.81 |
| MT-CYB | -0.72 | -0.88 |
| IFI27 | -0.72 | -0.88 |
| S100B | -0.71 | -0.85 |
Section V. Pathway annotation
| Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
|---|---|---|---|
| ZHOU INFLAMMATORY RESPONSE LIVE DN | 384 | 220 | All SZGR 2.0 genes in this pathway |
| THUM SYSTOLIC HEART FAILURE DN | 244 | 147 | All SZGR 2.0 genes in this pathway |
| ZHOU INFLAMMATORY RESPONSE FIMA DN | 284 | 156 | All SZGR 2.0 genes in this pathway |
| KINSEY TARGETS OF EWSR1 FLII FUSION UP | 1278 | 748 | All SZGR 2.0 genes in this pathway |
| GOZGIT ESR1 TARGETS DN | 781 | 465 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN APOPTOSIS BY SERUM DEPRIVATION UP | 552 | 347 | All SZGR 2.0 genes in this pathway |
| GRAESSMANN RESPONSE TO MC AND SERUM DEPRIVATION UP | 211 | 136 | All SZGR 2.0 genes in this pathway |
| LI LUNG CANCER | 41 | 30 | All SZGR 2.0 genes in this pathway |
| MARTORIATI MDM4 TARGETS FETAL LIVER DN | 514 | 319 | All SZGR 2.0 genes in this pathway |
| BENPORATH SUZ12 TARGETS | 1038 | 678 | All SZGR 2.0 genes in this pathway |
| BENPORATH EED TARGETS | 1062 | 725 | All SZGR 2.0 genes in this pathway |
| BENPORATH ES WITH H3K27ME3 | 1118 | 744 | All SZGR 2.0 genes in this pathway |
| BENPORATH PRC2 TARGETS | 652 | 441 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE INCIPIENT UP | 390 | 242 | All SZGR 2.0 genes in this pathway |
| BLALOCK ALZHEIMERS DISEASE UP | 1691 | 1088 | All SZGR 2.0 genes in this pathway |
| KONDO EZH2 TARGETS | 245 | 148 | All SZGR 2.0 genes in this pathway |
| 国外RB1增长目标 | 243 | 155 | All SZGR 2.0 genes in this pathway |
| CHICAS RB1 TARGETS CONFLUENT | 567 | 365 | All SZGR 2.0 genes in this pathway |
| BRUINS UVC RESPONSE VIA TP53 GROUP A | 898 | 516 | All SZGR 2.0 genes in this pathway |
| MIYAGAWA TARGETS OF EWSR1 ETS FUSIONS UP | 259 | 159 | All SZGR 2.0 genes in this pathway |
| ZWANG TRANSIENTLY UP BY 2ND EGF PULSE ONLY | 1725 | 838 | All SZGR 2.0 genes in this pathway |