Gene Page:CAPS

Summary?
GeneID 828
Symbol CAPS
Synonyms CAPS1
Description calcyphosine
Reference MIM:114212|HGNC:HGNC:1487|Ensembl:ENSG00000105519|HPRD:00250|Vega:OTTHUMG00000180619
Gene type protein-coding
Map location 19p13.3
Pascal p-value 0.579
Sherlock p-value 0.921
Fetal beta -0.273
DMG 1 (# studies)
eGene Myers' cis & trans

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS
DMG:Wockner_2014 Genome-wide DNA methylation analysis This dataset includes 4641 differentially methylated probes corresponding to 2929 unique genes between schizophrenia patients (n=24) and controls (n=24). 1
PMID:cooccur High-throughput literature-search Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
Literature High-throughput literature-search 与Sc Co-occurancehizophrenia keywords: schizophrenia,schizophrenic,schizophrenias Click to show details

Section I. Genetics and epigenetics annotation

@Differentially methylated gene

Probe Chromosome Position Nearest gene P (dis) Beta (dis) FDR (dis) Study
cg07535740 19 5915494 CAPS 1.98E-4 -0.257 0.035 DMG:Wockner_2014

@eQTL annotation

SNP ID Chromosome Position eGene Gene Entrez ID pvalue qvalue TSS distance eQTL type
rs17360973 chr1 25197276 CAPS 828 0.14 trans
rs12122035 chr1 50726051 CAPS 828 6.21E-5 trans
rs17109968 chr1 54633542 CAPS 828 0 trans
rs3754260 chr1 57552238 CAPS 828 0.05 trans
rs7541477 chr1 68764659 CAPS 828 3.617E-4 trans
rs10159115 chr1 68789890 CAPS 828 0.02 trans
rs7511937 0 CAPS 828 0.03 trans
rs2782784 chr1 71195282 CAPS 828 0.12 trans
rs17541646 chr1 71373644 CAPS 828 0.07 trans
rs6703905 chr1 89656748 CAPS 828 0.08 trans
rs6659821 chr1 110339827 CAPS 828 0.03 trans
snp_a-1965574 0 CAPS 828 0.16 trans
rs10797912 chr1 183785173 CAPS 828 0.01 trans
rs2491444 chr1 183785595 CAPS 828 0.01 trans
rs17049050 chr1 219294926 CAPS 828 0.01 trans
rs12617409 chr2 1649924 CAPS 828 0.18 trans
snp_a-1953711 0 CAPS 828 0.17 trans
rs6713473 chr2 11284414 CAPS 828 0.12 trans
rs908276 chr2 11285692 CAPS 828 0.19 trans
rs11903207 chr2 11286089 CAPS 828 0.19 trans
rs2543668 chr2 24447490 CAPS 828 0.2 trans
rs2551132 chr2 24566587 CAPS 828 0.17 trans
rs11692361 chr2 66723698 CAPS 828 0.11 trans
rs7561516 chr2 101059209 CAPS 828 0.01 trans
rs17024415 chr2 101108828 CAPS 828 0.01 trans
rs17024434 chr2 101112463 CAPS 828 0.01 trans
rs12614705 chr2 101122720 CAPS 828 0.01 trans
rs17024473 chr2 101139101 CAPS 828 0.01 trans
rs13412567 chr2 110457213 CAPS 828 0.05 trans
rs10186260 chr2 129538777 CAPS 828 0.01 trans
rs2683815 chr2 142078002 CAPS 828 6.015E-4 trans
rs6413977 0 CAPS 828 3.629E-5 trans
rs4346320 chr2 142150284 CAPS 828 3.629E-5 trans
rs7565413 chr2 142151284 CAPS 828 3.629E-5 trans
rs10497012 chr2 148319726 CAPS 828 0.04 trans
rs16827839 chr2 150987417 CAPS 828 1.157E-6 trans
rs11679772 chr2 158292302 CAPS 828 0.02 trans
rs16843564 chr2 159877285 CAPS 828 0.01 trans
rs264663 chr2 159910205 CAPS 828 0.01 trans
rs12476502 chr2 172086674 CAPS 828 0 trans
rs2674600 chr2 182917339 CAPS 828 0.17 trans
rs3731885 chr2 220084468 CAPS 828 0.09 trans
rs6723299 chr2 220125203 CAPS 828 0.09 trans
rs10203144 chr2 238024758 CAPS 828 0.05 trans
rs1814902 chr3 43251753 CAPS 828 0.04 trans
rs9681394 chr3 43256230 CAPS 828 5.042E-4 trans
rs4683367 chr3 43257826 CAPS 828 0.04 trans
rs7621511 chr3 43279877 CAPS 828 0.04 trans
rs4682682 chr3 43387222 CAPS 828 0.05 trans
rs17075597 chr3 43396220 CAPS 828 0.05 trans
rs17053128 chr3 53553459 CAPS 828 2.203E-4 trans
rs6795912 chr3 66700815 CAPS 828 3.516E-4 trans
rs4327353 chr3 71403693 CAPS 828 0.13 trans
rs16861358 chr3 113542315 CAPS 828 0.06 trans
rs6766110 chr3 156043032 CAPS 828 0.01 trans
rs9824778 chr3 156071119 CAPS 828 0.01 trans
rs16826030 chr3 156082850 CAPS 828 0.01 trans
rs7619608 chr3 172541129 CAPS 828 0.12 trans
rs16898145 chr4 19243840 CAPS 828 0.05 trans
rs2215848 chr4 25065220 CAPS 828 0 trans
rs1865660 chr4 30309146 CAPS 828 0.12 trans
rs1981925 chr4 34348578 CAPS 828 3.853E-9 trans
rs1542988 chr4 41009491 CAPS 828 0.07 trans
rs1542990 chr4 41009745 CAPS 828 0.01 trans
rs6832671 chr4 41010022 CAPS 828 0.07 trans
rs16851670 chr4 41017226 CAPS 828 0.07 trans
rs7683150 chr4 41028441 CAPS 828 0.07 trans
rs16852734 chr4 41030109 CAPS 828 0.07 trans
rs10006892 chr4 66308480 CAPS 828 0.18 trans
rs2291715 chr4 75485871 CAPS 828 0.01 trans
rs17017726 chr4 91768656 CAPS 828 0.03 trans
rs6836195 chr4 120756689 CAPS 828 0.01 trans
rs2647125 chr4 125949981 CAPS 828 0.01 trans
rs17252095 chr5 35466080 CAPS 828 0.01 trans
rs764912 chr5 35476733 CAPS 828 0.05 trans
rs2102438 chr5 35507735 CAPS 828 0.02 trans
rs435331 chr5 35541773 CAPS 828 0.17 trans
rs2468527 chr5 36515582 CAPS 828 0.05 trans
rs6862696 chr5 66724676 CAPS 828 0.02 trans
rs2950032 chr5 89438994 CAPS 828 0.04 trans
rs6898716 chr5 89439104 CAPS 828 0.14 trans
rs16868422 chr5 89573849 CAPS 828 1.381E-4 trans
rs10515239 chr5 95852768 CAPS 828 0.17 trans
rs10054076 chr5 96701778 CAPS 828 0.03 trans
rs1350578 chr5 116310282 CAPS 828 0.01 trans
rs9327725 chr5 134887432 CAPS 828 0.02 trans
rs1432789 chr5 160172598 CAPS 828 0.04 trans
snp_a-2275210 0 CAPS 828 0.2 trans
rs7740689 chr6 7888065 CAPS 828 0.14 trans
rs16874593 chr6 14040008 CAPS 828 5.548E-5 trans
rs647531 chr6 16776745 CAPS 828 0.02 trans
rs16881502 chr6 18933418 CAPS 828 0.06 trans
rs16889143 chr6 36757182 CAPS 828 0.1 trans
rs12663450 chr6 38135729 CAPS 828 0.01 trans
rs2268637 chr6 39050917 CAPS 828 2.973E-17 trans
rs16896683 chr6 43687846 CAPS 828 1.44E-4 trans
rs2815732 chr6 73151761 CAPS 828 1.199E-5 trans
rs1891395 chr6 73660343 CAPS 828 0.06 trans
rs4839895 chr6 97478137 CAPS 828 0.05 trans
rs9399023 chr6 132731357 CAPS 828 0.15 trans
rs6914861 chr6 138719751 CAPS 828 0.17 trans
rs10253642 chr7 19250373 CAPS 828 0.08 trans
rs12667955 chr7 30878707 CAPS 828 0 trans
rs17160028 chr7 31292738 CAPS 828 0.18 trans
rs10486710 chr7 41315585 CAPS 828 1.198E-4 trans
rs17564776 chr7 54888058 CAPS 828 0.01 trans
rs2287179 chr7 92080394 CAPS 828 0.05 trans
rs17138714 chr7 116114273 CAPS 828 0.03 trans
rs1049334 chr7 116200379 CAPS 828 0.03 trans
rs38847 chr7 116325325 CAPS 828 3.092E-6 trans
rs41796 chr7 116510238 CAPS 828 1.965E-7 trans
rs7791922 chr7 125130234 CAPS 828 0.02 trans
rs2524879 chr7 125222439 CAPS 828 0.06 trans
rs2524880 chr7 125222519 CAPS 828 0.06 trans
rs834063 chr7 137227543 CAPS 828 0.14 trans
rs3823550 chr7 137346101 CAPS 828 0 trans
rs17161272 chr7 139636617 CAPS 828 0.1 trans
snp_a-1911731 0 CAPS 828 0.09 trans
rs10235838 chr7 147798728 CAPS 828 0.15 trans
rs17152930 chr8 11010825 CAPS 828 0 trans
rs17056484 chr8 26848327 CAPS 828 5.298E-4 trans
rs7013952 chr8 26848444 CAPS 828 1.217E-5 trans
rs17056530 chr8 26850758 CAPS 828 4.068E-5 trans
rs17056895 chr8 27064032 CAPS 828 0.11 trans
rs7465259 0 CAPS 828 0.16 trans
rs10104622 chr8 63333773 CAPS 828 0.16 trans
rs2218911 chr8 63371015 CAPS 828 0.16 trans
rs1551199 chr8 63388117 CAPS 828 0.16 trans
rs12544529 chr8 74106553 CAPS 828 0.19 trans
rs3102477 chr8 96746099 CAPS 828 0.01 trans
rs16899930 chr8 125666587 CAPS 828 0.2 trans
rs4909503 chr8 136671520 CAPS 828 0.04 trans
rs16925320 chr9 890523 CAPS 828 0.03 trans
rs16925404 chr9 892999 CAPS 828 0.09 trans
rs1033833 chr9 894408 CAPS 828 0.09 trans
rs16925457 chr9 894713 CAPS 828 0.09 trans
rs10970372 chr9 31470279 CAPS 828 0.14 trans
rs7041035 chr9 31472314 CAPS 828 0.16 trans
rs16917077 chr9 31532211 CAPS 828 0.07 trans
rs817830 chr9 110154420 CAPS 828 0.16 trans
rs16913986 chr9 111968294 CAPS 828 0.12 trans
rs7846857 chr9 118043488 CAPS 828 0.02 trans
rs16909312 chr9 122771462 CAPS 828 0.05 trans
rs2002822 chr9 122776531 CAPS 828 0.01 trans
rs12349092 chr9 124018184 CAPS 828 0.2 trans
rs6478513 chr9 124238226 CAPS 828 0.04 trans
rs17294054 chr10 1719371 CAPS 828 0.05 trans
rs17294061 chr10 1720739 CAPS 828 0.05 trans
rs12570407 chr10 1854772 CAPS 828 0.16 trans
rs636819 chr10 6499605 CAPS 828 0.18 trans
rs10458641 chr10 77406953 CAPS 828 0.11 trans
rs10824325 chr10 77410900 CAPS 828 0.11 trans
rs1864486 chr10 77411623 CAPS 828 0.05 trans
rs17746747 chr10 84571921 CAPS 828 0.01 trans
rs1421049 chr10 113754346 CAPS 828 0.13 trans
rs7920992 chr10 130402940 CAPS 828 0 trans
rs4838740 chr10 135206353 CAPS 828 0.17 trans
rs12421276 chr11 4870498 CAPS 828 0.02 trans
rs1486220 chr11 94650449 CAPS 828 0.06 trans
rs16922394 chr11 95419045 CAPS 828 0.17 trans
rs17836464 chr12 4066927 CAPS 828 0.05 trans
rs11044062 chr12 8371319 CAPS 828 2.694E-4 trans
rs16933408 chr12 29001173 CAPS 828 0.08 trans
rs16933414 chr12 29001961 CAPS 828 0.05 trans
rs16933429 chr12 29003503 CAPS 828 0.18 trans
rs10506043 chr12 29003596 CAPS 828 0.18 trans
rs16933478 chr12 29026033 CAPS 828 0 trans
rs11838106 chr12 29026122 CAPS 828 0.15 trans
rs17174558 chr12 32994828 CAPS 828 0.12 trans
rs10877174 chr12 59236728 CAPS 828 0.01 trans
rs11172758 chr12 59238385 CAPS 828 0.05 trans
rs10877185 chr12 59297985 CAPS 828 6.037E-4 trans
rs11172818 chr12 59298289 CAPS 828 0.01 trans
rs10784924 chr12 71927246 CAPS 828 0.19 trans
rs11106191 chr12 78060911 CAPS 828 0.01 trans
rs10746188 chr12 81718315 CAPS 828 0.08 trans
rs11065588 chr12 121914241 CAPS 828 0.15 trans
rs12815249 chr12 130677246 CAPS 828 0.13 trans
rs1538922 chr13 29185821 CAPS 828 0.17 trans
rs4943304 chr13 36058065 CAPS 828 0.19 trans
rs7320986 chr13 61267175 CAPS 828 0.18 trans
rs7316938 chr13 73991407 CAPS 828 0.02 trans
rs9582434 chr13 101581060 CAPS 828 0.2 trans
rs8003636 chr14 59381327 CAPS 828 0.19 trans
rs85425 chr14 59384952 CAPS 828 0.11 trans
rs1209157 chr14 102082909 CAPS 828 0.15 trans
rs2091236 chr15 31180458 CAPS 828 0.12 trans
rs2701519 chr15 37408650 CAPS 828 0.01 trans
rs2701517 chr15 37411019 CAPS 828 0.16 trans
rs3973348 chr15 39694651 CAPS 828 0.06 trans
rs640875 chr15 40376395 CAPS 828 0.11 trans
rs8026050 chr15 45142418 CAPS 828 0.06 trans
rs16975906 chr15 45144803 CAPS 828 0.06 trans
rs16960698 chr15 48523283 CAPS 828 0.05 trans
rs16976035 chr15 96604839 CAPS 828 0.06 trans
rs1553612 chr16 7605345 CAPS 828 0.01 trans
snp_a-4226262 0 CAPS 828 0.05 trans
rs1406181 chr16 8442603 CAPS 828 0.11 trans
rs12599418 chr16 8443101 CAPS 828 0.11 trans
rs12599961 chr16 8443409 CAPS 828 0.03 trans
rs13338548 chr16 31472602 CAPS 828 0.12 trans
snp_a-2238348 0 CAPS 828 0.02 trans
rs4782606 chr16 84351788 CAPS 828 0.19 trans
rs11648858 chr16 85832291 CAPS 828 0.01 trans
rs2228133 chr17 7412402 CAPS 828 0.01 trans
rs11656351 chr17 9489574 CAPS 828 3.665E-5 trans
rs11078060 chr17 12119478 CAPS 828 0.09 trans
rs9893703 chr17 35175331 CAPS 828 0.08 trans
rs7219986 chr17 53263206 CAPS 828 0.01 trans
rs9909402 chr17 71721265 CAPS 828 0 trans
rs312907 chr17 75431977 CAPS 828 0.08 trans
rs500876 chr18 4388536 CAPS 828 0 trans
rs16953782 chr18 8564832 CAPS 828 1.942E-4 trans
rs2034023 chr18 8589186 CAPS 828 0.17 trans
rs9949772 chr18 31042632 CAPS 828 0 trans
rs16951170 chr18 47402487 CAPS 828 0.02 trans
rs1942461 chr18 70509159 CAPS 828 0.02 trans
rs1942462 chr18 70509823 CAPS 828 0.02 trans
rs1942463 chr18 70509841 CAPS 828 0.02 trans
rs1942464 chr18 70509877 CAPS 828 0 trans
rs1942466 chr18 70517154 CAPS 828 0.02 trans
rs2156494 chr18 70518084 CAPS 828 0.02 trans
rs884230 chr18 74331309 CAPS 828 0.15 trans
rs10425739 chr19 29582202 CAPS 828 0.11 trans
rs16962554 chr19 29590544 CAPS 828 2.337E-8 trans
rs7256478 chr19 52373987 CAPS 828 0.17 trans
rs7268977 chr20 221536 CAPS 828 0.03 trans
rs3790267 chr20 19565692 CAPS 828 0.01 trans
rs6515028 chr20 19576068 CAPS 828 0.01 trans
rs6035760 chr20 20993286 CAPS 828 0.18 trans
rs7268640 chr20 47150267 CAPS 828 1.167E-4 trans
rs259991 chr20 57728347 CAPS 828 0.03 trans
rs6015452 chr20 57782312 CAPS 828 0.05 trans
rs4270401 chr20 61343887 CAPS 828 0.12 trans
rs2826760 chr21 22645100 CAPS 828 0.04 trans
rs1893573 chr21 27965705 CAPS 828 2.014E-4 trans
rs16994521 chr21 38208009 CAPS 828 0.04 trans
rs14115 chr22 30163525 CAPS 828 0.12 trans
rs17711508 chr22 30220833 CAPS 828 0.12 trans
rs16988381 chr22 30592807 CAPS 828 0.07 trans
rs2267312 chr22 34288043 CAPS 828 1.551E-8 trans
rs7052166 chrX 17716493 CAPS 828 0.01 trans
rs7062071 chrX 17724830 CAPS 828 9.117E-4 trans
rs16983508 chrX 99747940 CAPS 828 0.08 trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

前co-expressed genes in brain regions

前10 positively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
NDUFA10 0.90 0.84
ARFIP2 0.90 0.82
RAB7A 0.88 0.83
SNAP47 0.88 0.77
TFG 0.86 0.76
ACAD9 0.86 0.77
C11orf49 0.86 0.79
C20orf3 0.86 0.77
MED8 0.86 0.77
ATP5B 0.85 0.79
前10 negatively co-expressed genes
Gene Pearson's Correlation Spearman's Correlation
AF347015.21 -0.77 -0.53
AF347015.2 -0.73 -0.51
AF347015.8 -0.73 -0.52
MT-CO2 -0.73 -0.51
AF347015.18 -0.72 -0.56
MT-CYB -0.71 -0.51
AF347015.31 -0.70 -0.50
AF347015.26 -0.69 -0.50
AF347015.27 -0.68 -0.53
AF347015.15 -0.68 -0.49

Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
SENGUPTA NASOPHARYNGEAL CARCINOMA DN 349 157 All SZGR 2.0 genes in this pathway
ODONNELL TFRC TARGETS UP 456 228 All SZGR 2.0 genes in this pathway
DODD NASOPHARYNGEAL CARCINOMA UP 1821 933 All SZGR 2.0 genes in this pathway
COLDREN GEFITINIB RESISTANCE DN 230 115 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS POORLY UP 236 139 All SZGR 2.0 genes in this pathway
RICKMAN TUMOR DIFFERENTIATED WELL VS MODERATELY UP 109 69 All SZGR 2.0 genes in this pathway
BENPORATH CYCLING GENES 648 385 All SZGR 2.0 genes in this pathway
MOREAUX MULTIPLE MYELOMA BY TACI UP 412 249 All SZGR 2.0 genes in this pathway
MOREAUX B LYMPHOCYTE MATURATION BY TACI UP 92 58 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 2 473 224 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720 440 All SZGR 2.0 genes in this pathway
ENGELMANN CANCER PROGENITORS DN 70 44 All SZGR 2.0 genes in this pathway
CHANDRAN METASTASIS DN 306 191 All SZGR 2.0 genes in this pathway
WHITFIELD CELL CYCLE S 162 86 All SZGR 2.0 genes in this pathway