Gene Page:HIST1H4D
Summary?
GeneID | 8360 |
Symbol | HIST1H4D |
Synonyms | H4/b|H4FB|dJ221C16.9 |
Description | histone cluster 1, H4d |
Reference | MIM:602823|HGNC:HGNC:4782|Ensembl:ENSG00000277157|HPRD:11914|Vega:OTTHUMG00000014423 |
Gene type | protein-coding |
Map location | 6p22.2 |
Pascal p-value | 0.002 |
eGene | Myers' cis & trans |
Gene in Data Sources
Gene set name | Method of gene set | Description | Info |
---|---|---|---|
CV:PGCnp | Genome-wide Association Study | GWAS | |
GSMA_I | Genome scan meta-analysis | Psr: 0.033 |
Section I. Genetics and epigenetics annotation
eQTL annotation
SNP ID | Chromosome | Position | eGene | Gene Entrez ID | pvalue | qvalue | TSS distance | eQTL type |
---|---|---|---|---|---|---|---|---|
rs17012898 | chr2 | 33601648 | HIST1H4D | 8360 | 0.14 | trans | ||
rs17012916 | chr2 | 33606031 | HIST1H4D | 8360 | 0.19 | trans | ||
rs2716734 | chr2 | 39947720 | HIST1H4D | 8360 | 0 | trans | ||
rs2716736 | chr2 | 39947946 | HIST1H4D | 8360 | 0 | trans | ||
rs17044826 | chr3 | 66620522 | HIST1H4D | 8360 | 0.1 | trans | ||
rs17023105 | chr4 | 96074164 | HIST1H4D | 8360 | 0.13 | trans | ||
snp_a-2169623 | 0 | HIST1H4D | 8360 | 0.05 | trans | |||
rs1474284 | chr7 | 67987882 | HIST1H4D | 8360 | 0.02 | trans | ||
rs2294031 | chr8 | 1812077 | HIST1H4D | 8360 | 0.07 | trans | ||
rs870686 | chr8 | 25253521 | HIST1H4D | 8360 | 0.07 | trans | ||
rs10503771 | chr8 | 25304019 | HIST1H4D | 8360 | 0.03 | trans | ||
rs12255258 | chr10 | 106306927 | HIST1H4D | 8360 | 6.364E-4 | trans | ||
rs17126694 | chr14 | 54103604 | HIST1H4D | 8360 | 0.09 | trans |
Section II. Transcriptome annotation
General gene expression (GTEx)
![Not available](http://www.tjghsg.com/bioinfo/SZGR/GeneImg/HIST1H4D_DE_GTEx.png)
Gene expression of temporal and spatial changes (BrainSpan)
Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception周),ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.
No co-expressed genes in brain regions
Section V. Pathway annotation
Pathway name | Pathway size | # SZGR 2.0 genes in pathway | Info |
---|---|---|---|
KEGG SYSTEMIC LUPUS ERYTHEMATOSUS | 140 | 100 | All SZGR 2.0 genes in this pathway |
REACTOME MEIOSIS | 116 | 81 | All SZGR 2.0 genes in this pathway |
REACTOME CELL CYCLE | 421 | 253 | All SZGR 2.0 genes in this pathway |
REACTOME RNA POL I TRANSCRIPTION | 89 | 64 | All SZGR 2.0 genes in this pathway |
REACTOME TRANSCRIPTION | 210 | 127 | All SZGR 2.0 genes in this pathway |
REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION | 122 | 80 | All SZGR 2.0 genes in this pathway |
REACTOME CHROMOSOME MAINTENANCE | 122 | 80 | All SZGR 2.0 genes in this pathway |
REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | 64 | 43 | All SZGR 2.0 genes in this pathway |
REACTOME RNA POL I PROMOTER OPENING | 62 | 49 | All SZGR 2.0 genes in this pathway |
REACTOME MEIOTIC RECOMBINATION | 86 | 62 | All SZGR 2.0 genes in this pathway |
REACTOME MEIOTIC SYNAPSIS | 73 | 57 | All SZGR 2.0 genes in this pathway |
REACTOME AMYLOIDS | 83 | 63 | All SZGR 2.0 genes in this pathway |
REACTOME PACKAGING OF TELOMERE ENDS | 48 | 40 | All SZGR 2.0 genes in this pathway |
REACTOME TELOMERE MAINTENANCE | 75 | 57 | All SZGR 2.0 genes in this pathway |
NUYTTEN EZH2 TARGETS DN | 1024 | 594 | All SZGR 2.0 genes in this pathway |
GARCIA TARGETS OF FLI1 AND DAX1 DN | 176 | 104 | All SZGR 2.0 genes in this pathway |
SCHAEFFER PROSTATE DEVELOPMENT 6HR DN | 514 | 330 | All SZGR 2.0 genes in this pathway |
BENPORATH EED TARGETS | 1062 | 725 | All SZGR 2.0 genes in this pathway |
MARSON BOUND BY FOXP3 STIMULATED | 1022 | 619 | All SZGR 2.0 genes in this pathway |
MARSON BOUND BY FOXP3 UNSTIMULATED | 1229 | 713 | All SZGR 2.0 genes in this pathway |
MARSON BOUND BY E2F4 UNSTIMULATED | 728 | 415 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER WITH H3K27ME3 DN | 228 | 114 | All SZGR 2.0 genes in this pathway |
ACEVEDO LIVER CANCER WITH H3K9ME3 DN | 120 | 71 | All SZGR 2.0 genes in this pathway |
TOYOTA TARGETS OF MIR34B AND MIR34C | 463 | 262 | All SZGR 2.0 genes in this pathway |
DANG BOUND BY MYC | 1103 | 714 | All SZGR 2.0 genes in this pathway |
ZWANG CLASS 1 TRANSIENTLY INDUCED BY EGF | 516 | 308 | All SZGR 2.0 genes in this pathway |
Section VI. microRNA annotation
miRNA family | Target position | miRNA ID | miRNA seq | ||
---|---|---|---|---|---|
UTR start | UTR end | Match method | |||
miR-328 | 45 | 51 | m8 | hsa-miR-328brain | CUGGCCCUCUCUGCCCUUCCGU |
- SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Clickhereto see the list of SZ related miRNAs.
- Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Clickhereto see the list of brain related miRNAs.