Gene Page:CTTNBP2

Summary?
GeneID 83992
Symbol CTTNBP2
Synonyms C7orf8|CORTBP2|Orf4
Description cortactin binding protein 2
Reference MIM:609772|HGNC:HGNC:15679|Ensembl:ENSG00000077063|HPRD:09890|Vega:OTTHUMG00000022880
Gene type protein-coding
Map location 7q31
Pascal p-value 0.008
支持 G2Cdb.humanPSD
G2Cdb.humanPSP

Gene in Data Sources
Gene set name Method of gene set Description Info
CV:PGCnp Genome-wide Association Study GWAS

Section I. Genetics and epigenetics annotation

@认为table

Gene Chromosome Position Ref Alt Transcript AA change Mutation type Sift CG46 Trait Study
CTTNBP2 chr7 117422921 A G NM_033427 . silent Schizophrenia 认为:Fromer_2014


Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
死神:胎儿(13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

No co-expressed genes in brain regions


Section IV. Protein-protein interaction annotation

Interactors Aliases B Official full name B Experimental Source PubMed ID
CCT2 99D8.1 | CCT-beta | CCTB | MGC142074 | MGC142076 | PRO1633 | TCP-1-beta chaperonin containing TCP1, subunit 2 (beta) Affinity Capture-MS BioGRID 18782753
CCT3 CCT-gamma | CCTG | PIG48 | TCP-1-gamma | TRIC5 chaperonin containing TCP1, subunit 3 (gamma) Affinity Capture-MS BioGRID 18782753
CCT5 CCT-epsilon | CCTE | KIAA0098 | TCP-1-epsilon chaperonin containing TCP1, subunit 5 (epsilon) Affinity Capture-MS BioGRID 18782753
CCT6A CCT-zeta | CCT-zeta-1 | CCT6 | Cctz | HTR3 | MGC126214 | MGC126215 | MoDP-2 | TCP-1-zeta | TCP20 | TCPZ | TTCP20 chaperonin containing TCP1, subunit 6A (zeta 1) Affinity Capture-MS BioGRID 18782753
CCT8 C21orf112 | Cctq | D21S246 | KIAA0002 | PRED71 chaperonin containing TCP1, subunit 8 (theta) Affinity Capture-MS BioGRID 18782753
CTTNBP2NL DKFZp547A023 | FLJ13278 CTTNBP2 N-terminal like Affinity Capture-MS BioGRID 18782753
FAM40A FLJ14743 | KIAA1761 | MGC148091 | RP4-773N10.1 family with sequence similarity 40, member A Affinity Capture-MS BioGRID 18782753
FAM40B - family with sequence similarity 40, member B Affinity Capture-MS BioGRID 18782753
MOBKL3 2C4D | CGI-95 | MGC12264 | MOB1 | MOB3 | PREI3 MOB1, Mps One Binder kinase activator-like 3 (yeast) Affinity Capture-MS BioGRID 18782753
PDCD10 CCM3 | MGC1212 | MGC24477 | TFAR15 programmed cell death 10 Affinity Capture-MS BioGRID 18782753
PPP2CA PP2Ac | PP2CA | RP-C protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform Affinity Capture-MS BioGRID 18782753
PPP2CB PP2CB protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform Affinity Capture-MS BioGRID 18782753
PPP2R1A MGC786 | PR65A protein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform Affinity Capture-MS BioGRID 18782753
RP6-213H19.1 MASK | MST4 serine/threonine protein kinase MST4 Affinity Capture-MS BioGRID 18782753
STK24 MST-3 | MST3 | MST3B | STE20 | STK3 serine/threonine kinase 24 (STE20 homolog, yeast) Affinity Capture-MS BioGRID 18782753
STRN MGC125642 | SG2NA striatin, calmodulin binding protein Affinity Capture-MS BioGRID 18782753
STRN3 SG2NA striatin, calmodulin binding protein 3 Affinity Capture-MS BioGRID 18782753
STRN4 FLJ35594 | ZIN | zinedin striatin, calmodulin binding protein 4 Affinity Capture-MS BioGRID 18782753
TCP1 CCT-alpha | CCT1 | CCTa | D6S230E | TCP-1-alpha t-complex 1 Affinity Capture-MS BioGRID 18782753


Section V. Pathway annotation

Pathway name Pathway size # SZGR 2.0 genes in pathway Info
SENGUPTA NASOPHARYNGEAL CARCINOMA WITH LMP1 UP 408 247 All SZGR 2.0 genes in this pathway
HAMAI APOPTOSIS VIA TRAIL UP 584 356 All SZGR 2.0 genes in this pathway
MIDORIKAWA AMPLIFIED IN LIVER CANCER 55 38 All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR DN 428 306 All SZGR 2.0 genes in this pathway
CUI TCF21 TARGETS 2 DN 830 547 All SZGR 2.0 genes in this pathway
CREIGHTON ENDOCRINE THERAPY RESISTANCE 3 720 440 All SZGR 2.0 genes in this pathway
RIGGI EWING SARCOMA PROGENITOR UP 430 288 All SZGR 2.0 genes in this pathway
ZHANG BREAST CANCER PROGENITORS UP 425 253 All SZGR 2.0 genes in this pathway